High-coverage allele-resolved single-cell DNA methylation profiling reveals cell lineage, X-inactivation state, and replication dynamics by Nathan J. Spix, Walid Abi Habib, Zhouwei Zhang, Emily Eugster, Hsiao-yun Milliron, David Sokol, KwangHo Lee, Paula A. Nolte, Jamie L. Endicott, Kelly F. Krzyzanowski, Toshinori Hinoue, Jacob Morrison, Benjamin K. Johnson, Wanding Zhou, Hui Shen, Peter W. Laird

“…Inefficient library generation and low CpG coverage mostly preclude direct cell-to-cell comparisons and necessitate the use of cluster-based analyses, imputation of methylation states, or averaging of DNA methylation measurements across large genomic bins. …”
Get full text

Reduction in DALYs lost due to soil-transmitted helminthiases and schistosomiasis from 2000 to 2019 is parallel to the increase in coverage of the global control programmes. by Antonio Montresor, Pauline Mwinzi, Denise Mupfasoni, Amadou Garba

“…Preventive chemotherapy interventions for the control of soil-transmitted helminthiases (STH) and schistosomiasis scaled up from a global coverage level of around 5% in the year 2000 to a coverage that surpassed 60% in the year 2019. …”
Get full text

Human papillomavirus vaccination at age 9 or 10 years to increase coverage – a narrative review of the literature, United States 2014–2024 by Sarah K. Brewer, Ruth Stefanos, Neil C. Murthy, Amimah F. Asif, Shannon Stokley, Lauri E. Markowitz

“…U.S. HPV vaccination coverage is lower than other adolescent vaccinations. …”
Get full text

The accuracy of capture per unit effort in predicting density of a cryptic snake was more sensitive to reductions in spatial than temporal coverage. by Melia G Nafus, Emma B Hanslowe, Scott M Goetz

“…The spatial area of coverage required for CPUE to accurately predict changes in abundance was, however, intense with > 50% of the spatial area required to be sampled on a given sampling night. …”
Get full text

Association of socio-demographic factors with measles vaccination coverage among Indonesian children aged 12-23 months: a nationwide study by Asep Hermawan, Irlina Raswanti Irawan, Mirna Widiyanti, Rosnani Rosnani, Hidayat Arifin

“…This study aimed to examine the socio-demographic factors associated with measles vaccination coverage among Indonesian children aged 12–23 months, using data from a nationally representative survey. …”
Get full text

Performance of Malaria Volunteers regarding Malaria Control Activities in Southeastern Myanmar: A Study in the Areas under Coverage of an Ethnic Health Organization by Ye Thiha, Thant Zin, Kyawt Mon Win, Myat Thu Soe, Pyae Linn Aung

Get full text

Effects of medication procurement reforms and extended prescription duration on medication coverage for hypertension in India’s public health system: a modelling study by Kunihiro Matsushita, Andrew E Moran, Matti Marklund, Prabhdeep Kaur, Lawrence J Appel, T Joseph Mattingly, Swagata Kumar Sahoo

“…Objectives To estimate the effects of procurement reforms and extended prescription duration on medication coverage for hypertension in India’s public health system.Design Simulation study incorporating data from governmental medication price lists, prescription pattern analyses, and market sales surveys.Setting Simulated hypothetical public healthcare facility in India treating 1000 patients with hypertension.Participants Patients with medication-treated hypertension.Interventions (1) Focused procurement by reducing antihypertensive medication classes from 5 to 3 and selecting one medication within class; (2) Increased use of single-pill combinations (SPC) and (3) Only SPC dispensation. …”
Get full text

The impact on urban accessibility conditions of a proposed cableway line in the city of Manizales, Colombia by Montoya Jorge Alberto, Aguilera Juan Camilo, Escobar Diego Alexander

Get full text

Vaccination coverage and factors associated with incomplete polio vaccine schedule in children born in 2017-2018, in state capitals and interior region municipalities of Northeast... by Alberto Novaes Ramos Jr., Ramon da Costa Saavedra, Adjoane Mauricio Silva Maciel, Anderson Fuentes Ferreira, Taynara Lais Silva, Luisa Helena de Oliveira Lima, Carla Magda Allan Santos Domingues, Jaqueline Caracas Barbosa, Ligia Regina Franco Sansigolo Kerr, Ana Paula França, Pallysson Paulo da Silva, Maria da Gloria Teixeira, José Cássio de Moraes, Adriana Ilha da Silva, Alberto Novaes Ramos Jr., Ana Paula França, Andrea de Nazaré Marvão Oliveira, Antonio Fernando Boing, Carla Magda Allan Santos Domingues, Consuelo Silva de Oliveira, Ethel Leonor Noia Maciel, Ione Aquemi Guibu, Isabelle Ribeiro Barbosa Mirabal, Jaqueline Caracas Barbosa, Jaqueline Costa Lima, José Cássio de Moraes, Karin Regina Luhm, Karlla Antonieta Amorim Caetano, Luisa Helena de Oliveira Lima, Maria Bernadete de Cerqueira Antunes, Maria da Gloria Teixeira, Maria Denise de Castro Teixeira, Maria Fernanda de Sousa Oliveira Borges, Rejane Christine de Sousa Queiroz, Ricardo Queiroz Gurgel, Rita Barradas Barata, Roberta Nogueira Calandrini de Azevedo, Sandra Maria do Valle Leone de Oliveira, Sheila Araújo Teles, Silvana Granado Nogueira da Gama, Sotero Serrate Mengue, Taynãna César Simões, Valdir Nascimento, Wildo Navegantes de Araújo

“…ABSTRACT Objective To analyse vaccination coverage and factors associated with incomplete polio vaccination in a cohort of children born in 2017-2018, in state capitals and interior region municipalities of Northeast Brazil. …”
Get full text

Household-based Survey of Diphtheria Vaccination in Osogbo Vis-à-vis 2023 Diphtheria Outbreak in Osun State, Nigeria: A Snapshot Assessment by Waidi Folorunso Sule, Hannah Ifedayo Ajayi, Ayokunle David Obayomi, Omolola Yinka Adeagbo, Omotayo Opemipo Oyedara, Olayode Olayiwola, Sunday Babatunde Akinde

“…Full diphtheria vaccination coverage (81.2% [95% CI: 75.9%–85.6%]) was acceptably high, with statistical association of five caregivers’ and two children’s variables. …”
Get full text

Epidemiology of sepsis in hospitalised neonates in Indonesia: high burden of multidrug-resistant infections reveals poor coverage provided by recommended antibiotic regimens by Michael Sharland, Tetty Yuniati, Nina Dwi Putri, Michelle Harrison, Jannah Baker, Dominicus Husada, Benjamin FR Dickson, Riyadi Adrizain, Leny Kartina, Distiayu Sukarja, Fabiola Cathleen, Martono T Utomo, Adhi K Suginali, Phoebe CM Williams

“…Overall, the pathogens causing neonatal sepsis exhibit very low susceptibility to WHO-recommended antibiotic regimens for the treatment of neonatal sepsis, with only 25% coverage provided by aminopenicillins plus gentamicin (95% credible interval (CI) 22% to 29%) and 20% by third-generation cephalosporins (95% CI 17% to 23%). …”
Get full text

Coverage, timeliness of measles immunisation and its predictors in Pakistan: an analysis of 6.2 million children enrolled in the Provincial Electronic Immunisation Registry by Subhash Chandir, Hamidreza Setayesh, Danya Arif Siddiqi, Sundus Iftikhar, Vijay Kumar Dharma, Mubarak Taighoon Shah, Manaksha Memon

“…Background Measles-related morbidity and mortality persists due to suboptimal and delayed vaccination, predominantly in low- and middle-income countries where more than 95% of global measles deaths occur. We evaluated the coverage, timeliness of measles vaccination and its predictors for children aged 12–23 months in Sindh, Pakistan.Methods We analysed immunisation data from Sindh Province's Electronic Immunisation Registry for 6.2 million children aged 12–23 months. …”
Get full text

Facebook Sentiment Analysis on Healthcare of Timor-Leste: Analysing public perception through social media by Cristovao De Alexandria Barros, Marcelo Amaral Mali, Evalisa Adão Mendonça, Osmenia de jesus Neto

Get full text

‘Who assisted with the delivery of (NAME)?’ Issues in estimating skilled birth attendant coverage through population-based surveys and implications for improving global tracking... by Emma Radovich, Loveday Penn-Kekana, Kerry Wong, Oona Maeve Renee Campbell

“…In response to the 2018 revised definition of SBA and the push for improved measurement of progress in maternal and newborn health, this paper examines the evidence on what women can tell us about who assisted them during childbirth and methodological issues in estimating SBA coverage via population-based surveys. We present analyses based on Demographic and Health Surveys and Multiple Indicator Cluster Surveys conducted since 2015 for 23 countries. …”
Get full text

Recent changes to adult national immunization programs for pneumococcal vaccination in Europe and how they impact coverage: A systematic review of published and grey literature by Stuti Arya, Nicholas Norton, Puneet Kaushik, Agnes Brandtmüller, Eleana Tsoumani

“…Third, most health economic analyses assessing higher-valency PCVs for adults found its inclusion in NIPs cost-effective. …”
Get full text

Coverage disparities and delayed immunization: Assessing 12-month vaccination completion in Canadian children using data from a digital immunization platform by Mohamed Serhan, Adhiba Nilormi, Blaise Ntacyabukura, Katherine Atkinson, Robin Ducharme, Steven Hawken, Tim Ramsay, Joyce Ang, Kumanan Wilson

“…We conducted bivariate and multivariate logistic regression analyses to investigate associations between factors such as account holder gender, active integration of vaccine record with a public health unit (PHU) and inclusion of linked records in CANImmunize, with vaccination coverage. …”
Get full text

Gaps in health coverage for racialized im/migrant sex workers in metro Vancouver: Findings of a community-based cohort study (2014–2021) by Shira M. Goldenberg, Maggie Hamel-Smith Grassby, Alaina Ge, Melissa Braschel, Charlie Zhou, Kate Shannon

“…We examined associations between im/migration status, duration, and racialization on gaps in health insurance coverage in a cohort of women sex workers. Methods: Analyses used data from a prospective, community-based cohort of women sex workers in Vancouver, BC (Sept 2014-August 2021). …”
Get full text

Low-coverage whole genome sequencing of cell-free DNA to predict and track immunotherapy response in advanced non-small cell lung cancer by Florian Janke, Mateo Gasser, Arlou K. Angeles, Anja L. Riediger, Magdalena Görtz, Louise Appenheimer, Astrid K. Laut, Simon Ogrodnik, Sabrina Gerhardt, Albrecht Stenzinger, Marc A. Schneider, Michael Thomas, Petros Christopoulos, Holger Sültmann

“…Methods Tumor-agnostic low-coverage ctDNA whole genome sequencing (lcWGS) was used to longitudinally track genome-wide copy number variations (CNVs) and fragmentation features in advanced NSCLC patients (n = 118 samples from 49 patients) and healthy controls (n = 57). …”
Get full text

Coverage estimation of benthic habitat features by semantic segmentation of underwater imagery from South-eastern Baltic reefs using deep learning models by Andrius Šiaulys, Evaldas Vaičiukynas, Saulė Medelytė, Kazimieras Buškus

“…However, the processing and analysing of vast amounts of imagery can become very labour-intensive, thus making it ineffective both time-wise and financially. …”
Get full text

Analysis of the utilisation of Chuna manual therapy for musculoskeletal disorders after its coverage under national health insurance in Korea: a retrospective analysis by In-Hyuk Ha, Yoon Jae Lee, Byung-Cheul Shin, Gil Geun Baek, Yeong-Jae Shin

Get full text