Serum and Urine Metabolic Fingerprints Characterize Renal Cell Carcinoma for Classification, Early Diagnosis, and Prognosis by Xiaoyu Xu, Yuzheng Fang, Qirui Wang, Shuanfeng Zhai, Wanshan Liu, Wanwan Liu, Ruimin Wang, Qiuqiong Deng, Juxiang Zhang, Jingli Gu, Yida Huang, Dingyitai Liang, Shouzhi Yang, Yonghui Chen, Jin Zhang, Wei Xue, Junhua Zheng, Yuning Wang, Kun Qian, Wei Zhai

“…For the early stage of RCC subtypes, the averaged diagnostic sensitivity of 90.5% and specificity of 91.3% in the test set is achieved. …”
Get full text

Hybrid closed-loop systems for managing blood glucose levels in type 1 diabetes: a systematic review and economic modelling by Asra Asgharzadeh, Mubarak Patel, Martin Connock, Sara Damery, Iman Ghosh, Mary Jordan, Karoline Freeman, Anna Brown, Rachel Court, Sharin Baldwin, Fatai Ogunlayi, Chris Stinton, Ewen Cummins, Lena Al-Khudairy

“…The EAG provides scenario analyses that estimate symptomatic and severe hypoglycaemia events based on the differences in the time < 3.0 mmol/l for HCL and CSII + CGM. …”
Get full text

A decade of Benzodiazepine and Z-drug use in Hong Kong: a longitudinal studyResearch in context by Kyung Jin Lee, Yue Wei, Shek-Ming Leung, Caige Huang, Hei Hang Edmund Yiu, Eunice Kehui Deng, David J. Castle, Simon S.Y. Lui, Vincent K.C. Wong, Ian C.K. Wong, Esther W. Chan

“…Methods: Using territory-wide electronic health record data from Hong Kong (2014–2023), we analysed the prevalence, incidence, and duration of BZD and Z-drug prescriptions in adults. …”
Get full text

Liver damage in patients living with HIV on antiretroviral treatment with normal baseline liver function and without HBV/HCV infection: an 11-year retrospective cohort study in Gua... by Jun Yu, Hao Liang, Fengxiang Qin, Junjun Jiang, Chunwei Qin, Yunxuan Huang, Bingyu Liang, Yuexiang Xu, Jiegang Huang, Zhiliang Xu, Chuanyi Ning, Yanyan Liao, Ning Zang, Jingzhen Lai, Wudi Wei, Li Ye, Xionglin Qin

“…The association between duration of ART and liver damage (grade II–IV liver enzyme elevation [LEE] and/or total bilirubin elevation [TBE]), was analysed. Cox regression was used to examine the factors related to liver damage.Results Of 2119 eligible patients, 12.41% (263/2119) developed liver damage (grade II–IV LEE/TBE) and contributed 4.11/100 person-years crude incidence rate. …”
Get full text

Effects of mosquito-proofing storm drains on adult and larval mosquito abundance: Protocol of the IDAlErt storm drAin randomiSed controlled trial (IDEAS) by Marina Treskova, Tomás Montalvo, Joacim Rocklöv, Charles Hatfield, Frederic Bartumeus, Shouro Dasgupta, João Encarnação, Rachel Lowe, Jan C. Semenza, Pascale Stiles, Jordi Noya, Andrea Valsecchi, Till Bärnighausen, John R.B. Palmer, Aditi Bunker

“…We will use generalised linear mixed models to estimate the time-averaged and peak mosquito month intervention effects, and conducted complimentary subgroup and sensitivity analyses. …”
Get full text

Global Burden of Oral Diseases in Adolescents and Young Adults Aged 10–24 Years by Wei Lu, Bing Wang, Mi Du, Shaohua Ge

“…Objectives: This study aims to analyse global trends in the burden of oral diseases, including dental caries and noncarious oral diseases (NCODs), in individuals aged 10 to 24 from 1990 to 2021 and project future trends up to 2050. …”
Get full text

Demographics, epidemiology, mortality and difficult-to-treat resistance patterns of bacterial bloodstream infections in the global US Military Health System from 2010 to 2019: a re... by Jing Wang, Carlos Morales, Dean Follmann, John H Powers, Alexander C Vostal, Melissa Grance, Sameer S Kadri, Sarah Warner, Uzo Chukwuma, Charlotte Lanteri, M Leigh Carson, Beth Poitras, Nicholas Seliga, Edward Parmelee, Katrin Mende

“…Crude mortality trends were assessed.Results The decade analysed included 15 357 BSI episodes in 12 748 patients; 6216 patients (48.8%) were≥65 years and 83.7% of episodes had≥1 comorbidity (12 856 of 15 357). …”
Get full text

Structures of immature EIAV Gag lattices reveal a conserved role for IP6 in lentivirus assembly. by Robert A Dick, Chaoyi Xu, Dustin R Morado, Vladyslav Kravchuk, Clifton L Ricana, Terri D Lyddon, Arianna M Broad, J Ryan Feathers, Marc C Johnson, Volker M Vogt, Juan R Perilla, John A G Briggs, Florian K M Schur

“…We have used in vitro assembly, cryo-electron tomography and subtomogram averaging, atomistic molecular dynamics simulations and mutational analyses to study the HIV-related lentivirus equine infectious anemia virus (EIAV). …”
Get full text

Diversification of macrophytes within aquatic nature-based solutions (NBS) developing under urban environmental conditions across European cities by Krzysztof Szoszkiewicz, Krzysztof Achtenberg, Robrecht Debbaut, Vladimíra Dekan Carreira, Daniel Gebler, Szymon Jusik, Tomasz Kałuża, Krister Karttunen, Niko Lehti, Silvia Martin Muñoz, Mariusz Sojka, Ana Júlia Pereira, Pedro Pinho, Jonas Schoelynck, Jan Staes, Doerthe Tetzlaff, Maria Magdalena Warter, Kati Vierikko

“…While aquatic NBS have been studied for engineering and social aspects, comprehensive biological analyses, particularly across geographical gradients, have been lacking. …”
Get full text

Peculiarity of Clinical Course of Childhood Hepatitis C Depending on the Viral Genotype by E. A. Leybman, L. I. Nikolaeva, E. I. Samokhvalov, K. K. Kyuregayn, O. V. Isaeva, G. V. Sapronov, T. V. Cherednechenko, A. G. Pisarev, A. E. Grishechkin, M. I. Michailov, V. F. Uchaikin

“…The aims of the study were to establish the structure of HCV genotype in infected children in Moscow region and to analyse the features of hepatitis, induced by different viral subtypes. …”
Get full text

Diverse actions of 15 structurally unrelated mitochondrial uncouplers in cells and mice by Divya P. Shah, Calum S. Vancuylenburg, Ellen M. Olzomer, Sing-Young Chen, Robert J. Grams, Martina Beretta, Frances L. Byrne, Webster L. Santos, Kyle L. Hoehn

“…Another group of mice was fed chow to receive ∼65% of the average daily food intake of control mice as a model of calorie restriction (CR). …”
Get full text

Study of optical scattering properties and direct radiative effects of high-altitude cirrus clouds in Barcelona, Spain, with 4 years of lidar measurements by C. Gil-Díaz, M. Sicard, M. Sicard, M. Sicard, O. Sourdeval, A. Saiprakash, C. Muñoz-Porcar, A. Comerón, A. Rodríguez-Gómez, D. C. F. D. S. Oliveira

“…Third, we present a case study analysing the direct radiative effect of a cirrus cloud along its back-trajectory using data from the Chemical LAgrangian Model of the Stratosphere with microphysics scheme for Ice clouds formation (CLaMS-Ice). …”
Get full text

Profil glucido-lipidique et risque cardiovasculaire chez les diabétiques de type 2 by Mourad Nachi, Ibtissem Kihel, Abdessamad Dali-Ali, Mouna Gourine, Fouzia Benrahal

“…Methods - It was about a retrospective study of 341 type 2 diabetes patients’ with an average age of 60.1 ± 11.71 years.The IBM® SPSS statistics 20.0 software was used for analyzing data. …”
Get full text

Dual Roles of HbA1c Variability and Body Composition for Cardiovascular Risk: A Cohort Study of 8224 Adults With Type 2 Diabetes Mellitus by Sunyoung Kim, Jiyoung Hwang, Dong Keon Yon, Hyunji Sang, Selin Woo, Ho Geol Woo, Hyunjung Lim, Jungha Park, Fei‐Yuan Hsiao, Liang‐Kung Chen, Sang Youl Rhee

“…Methods This retrospective cohort study analysed electronic health records from a university hospital (2011–2020), including 8224 adults (mean age 58.3 years, 50.1% women) with T2DM and no history of CVD. …”
Get full text

Sinhogarismo y salud mental: factores determinantes en la salida de la situación de calle en adultos residentes en un centro de acogida by Juan Manuel Rodilla, René Payri, Gloria Puchol, Maribel Pasarín

“…The methodology was based on pre-test post-test data, which was analysed by statistical tests. The study sample was composed by N=241 homeless adults who exit the housing program between 2019 and 2020. …”
Get full text

Effect of weaning and cow-calf contact on the physiological and clinical health, performance, and behaviour of dairy cows and their calves by S.E. McPherson, E.A.M. Bokkers, A.M. Sinnott, M.C. McFadden, L.E. Webb, E. Kennedy

“…After weaning and separation, the FT (0.36 mmol/L; P < 0.001) and PT (0.34 mmol/L; P = 0.001) calves had higher NEFA than CONV calves (0.13 mmol/L). Calf weekly average daily gain (ADGw) was similar preWS (0.9 ± 0.142 kg/d), but CONV calves had higher ADGw postWS than FT (0.42 kg/d) and PT calves (0.40 kg/d). …”
Get full text

Voluntary Activity Wheel Running Improves Hyperammonaemia‐Induced Skeletal Muscle Molecular and Metabolic Perturbations in Mice by Annette Bellar, Avinash Kumar, Khaviyaa Chandramohan, Saurabh Mishra, Muaz Alsabbagh‐Alchirazi, Artem Astafev, Pugazhendhi Kannan, Amy Attaway, Roman Kondratov, Thomas Jaramillo, Lopa Mishra, Takhar Kasumov, Nicole Welch, Srinivasan Dasarathy

“…Wheel runs were measured, and weekly average rotations, distance, and circadian patterns were analysed. …”
Get full text

Penentuan Lokasi Optimal Stasiun Bike Sharing Dalam Mendukung Pariwisata di Kota Surakarta by Muhammad Rizal Fernandita Pamungkas, Wartono Wartono, Danarti Karsono, Elisa Harlia Sandi, Allesandro Umbu Balla Rundi

“…Most of the bike sharing stations have an average distance of less than 3 kilometres to tourist attractions in Surakarta City. …”
Get full text

Profil glucido-lipidique et risque cardiovasculaire chez les diabétiques de type 2 by Mourad Nachi, Ibtissem Kihel, Abdessamad Dali-Ali, Mouna Gourine, Fouzia Benrahal

“…Methods - It was about a retrospective study of 341 type 2 diabetes patients’ with an average age of 60.1 ± 11.71 years.The IBM® SPSS statistics 20.0 software was used for analyzing data. …”
Get full text

Detection Method of Apple Alternaria Leaf Spot Based on Deep-Semi-NMF by FU Zhuojun, HU Zheng, DENG Yangjun, LONG Chenfeng, ZHU Xinghui

“…In a natural environment, where a dataset of 1 419 images of apple Alternaria leaf spot was analysed, DSNMFMAD demonstrated an 87.8% recognition accuracy, with an average detection speed of 0.091 0 s per image. …”
Get full text