A Randomized Controlled Trial: Evaluating the Impact of Mirror Therapy on Mobility, Motor Recovery, and Functional Independence after Stroke by Brijesh Kumar, Anjana Chandran, Ranjeet Kumar Sinha

“…Conclusion: Structured MT significantly enhances motor and functional recovery post-stroke, independent of sociodemographic factors. …”
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Effects of the High-Intensity Early Mobilization on Long-Term Functional Status of Patients with Mechanical Ventilation in the Intensive Care Unit by Chuanlin Zhang, Xueqin Wang, Jie Mi, Zeju Zhang, Xinyi Luo, Ruiying Gan, Shaoyu Mu

“…The aim of this study was to investigate whether high-intensity early mobility improves post-ICU discharge functional status of IMV patients. …”
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Fibroblasts‐specific p16INK4a exacerbates inflammageing‐mediated post‐infarction ventricular remodelling through interacting with STAT3 to regulate NLRP3 transcription by Xin Gu, Yingqiang Du, Jin'ge Zhang, Jiyu Li, Haiyun Chen, Yujie Lin, Yue Wang, Chunli Zhang, Shiyu Lin, Nannan Hao, Chengyi Peng, Jiacheng Ge, Jin Liu, Yan Liang, Yongjie Zhang, Xiaoyan Wang, Fang Wang, Jianliang Jin

“…POSTN‐driven p16INK4a knockout improved cardiac function, and reduced ventricular remodelling, myocardial inflammation and NLRP3 signalling activation following MI through downregulating STAT3‐mediated NLRP3 inflammasome and upregulating glutathione metabolism pathway in fibroblasts. …”
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Impact of digital health management on clinical outcomes during post-PCI outpatient care in patients with acute coronary syndrome: study protocol for a multicentre, randomized cont... by Hang Yu, Wei Zhang, Wei Zhang, Guoliang Li, Tao Chen, Shaonong Dang, Xiaofeng Ma, XiaoWei Zhang, Xiaofeng Ma, Zhibin Hong, Pengyi He, Xiaohui Xu, Xiuying Chen, Yanyan Geng, Xinjun Lei, Xinjun Lei

“…The primary clinical endpoint of this study is major adverse cardiovascular and cerebrovascular events (MACCEs), whereas the secondary clinical endpoints include cardiac function indicators, quality of life scores, and mental health scores, among other endpoints.ConclusionsThis clinical trial will provide evidence to demonstrate whether digital health management is a better approach for improving clinical outcomes in patients with post-PCI ACS.If proven effective, this digital model could address the global underutilization of cardiac rehabilitation by providing scalable, low-cost solutions, particularly in rural and resource-limited settings. …”
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Efficacy and safety of moxibustion treatment for upper extremity pain disorder and motor impairment in patients with stage I post-stroke shoulder-hand syndrome: a systematic review... by Xiaonan Meng, Xiaonan Meng, Jie Sun, Xintong Su, David Jung Seto, David Jung Seto, Liping Wang, Ying Li, Haikuo Yu, Baixiao Zhao, Jiping Zhao

“…There was no significant difference in the occurrence of adverse events (AEs) between corresponding experimental and control groups (RR = 1.62, 95% CI: 0.63, 4.16, p > 0.05).ConclusionThis study demonstrates that moxibustion as an adjuvant therapy may play a positive role in relieving pain and improving upper extremity motor function for patients with stage I SHS, given its convenience in generating prolonged effects in communities. …”
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Kyphoplasty as a Treatment Option for Traumatic Burst Fractures: A Case Series Evaluating Patient Outcomes and Functional Benefits by Anoop S. Chinthala, Barnabas Obeng-Gyasi, Trenton A. Line, Matthew K. Tobin, Gordon Mao, Bradley N. Bohnstedt

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Using Web-Based Continuing Education to Improve New Diagnoses of Alzheimer Disease in Claims Data: Retrospective Case-Control Study by Katie Lucero, Thomas Finnegan, Soo Borson

“…Early and accurate diagnosis of AD is crucial for effective management and care to enable timely treatment interventions that can preserve cognitive function and improve patient quality of life. However, there are often significant delays in diagnosis. …”
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Evaluation of the clinical effectiveness of bundled care interventions on pressure ulcer incidence in neurosurgical patients by Ai-Hua Lv, Xi Zhang, Xiu-Ling Sun, Xiu-Lan Liu, Jun-Qing Qi, Hui-Na Li

“…Emotional functioning also improved significantly, with the study group scoring 85.32 ± 2.05 compared to 76.41 ± 2.12 in the control group. …”
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Neddylation status determines the therapeutic sensitivity of tyrosine kinase inhibitors in chronic myeloid leukemia by Congyi Zhang, Yikai Yao, Qiuting Qian, Xiongyu Han, Yunkun Lu, Xinyi Jiang, Hongqiang Cheng, Xue Zhang, Ying Chi, Yuehai Ke, Peng Xiao

“…Hence, our study offers new insights into the post-translational modification (PTM)-mediated drug resistance, and highlights the potential clinical benefits of neddylation agonists in improving the responsiveness of BCR::ABL1 TKIs in CML.…”
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Cannulated intravaginal injection technique (CIVIT) A Novel Vaginal Injection Technique  by Ozgur Leylek, Berna Haliloglu Peker, Ergul Demircivi, Hakan Peker

“…However, CIVIT is significantly more effective than the random technique in improving genitourinary symptoms, vaginal health index and sexual function.…”
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Effects of music training on executive functions in preschool children aged 3–6 years: systematic review and meta-analysis by Yanan Lu, Lin Shi, Lin Shi, Ahmad Faudzi Musib

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Differential cognitive and clinical improvements in Schizophrenia and bipolar disorder following hospitalization: A comparative analysis based on the Clock Drawing Test. by Ahmad Pirani, Atiye Sarabi-Jamab, Faeze Bostan, Razieh Salehian, Mehran Ilaghi, Ali Aledavoud, Seyed Vahid Shariat, Fatemeh Sadat Mirfazeli

“…<h4>Conclusion</h4>While both groups exhibited cognitive and clinical improvements following hospitalization, patients with SCZ showed relatively less improvement in the CDT compared to those with BDP. …”
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Short-term outcome and predictors of post-operative complications following transurethral resection of the prostate among patients with benign prostate hyperplasia in Northern Tanz... by Esther E. Lekei, Jasper S. Mbwambo, Frank Bright, Magreth Elias, Zerra I. Cheyo, Alfred Kien Mteta, Orgeness Mbwambo, Bartholomeo Nicholaus Ngowi

“…The average change of IPSS score was 78.42% ± 18.62 (P ≤ 0.001), while for QoL was 76.22 ± 30.96 (P ≤ 0.001) hence significant improvement. Overall, 86 (58.9%) patients had at least one complication post-operative. …”
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Effects of Home-Based Computerized Cognitive Training in Community-Dwelling Adults With Mild Cognitive Impairment by Ji Soo Baik, Ji Hong Min, Sung-Hwa Ko, Mi Sook Yun, Byunghoon Lee, Nae Yoon Kang, Byeongil Kim, Hyunsuk Lee, Yong-Il Shin

“…Results: In baseline and post-evaluation comparisons, the HB-CCT group showed significant improvements, while the control group did not show significant changes. …”
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Metabolic Effects of Sodium Thiosulfate During Resuscitation from Trauma and Hemorrhage in Cigarette-Smoke-Exposed Cystathionine-γ-Lyase Knockout Mice by Maximilian Feth, Felix Hezel, Michael Gröger, Melanie Hogg, Fabian Zink, Sandra Kress, Andrea Hoffmann, Enrico Calzia, Ulrich Wachter, Peter Radermacher, Tamara Merz

“…In mice with a genetic deletion of the H₂S-producing enzyme cystathione-γ-lyase (CSE^−/−), providing exogenous H₂S using sodium thiosulfate (Na₂S₂O₃) improved organ function after chest trauma and hemorrhagic shock. …”
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Research on Personnel Image Segmentation Based on MobileNetV2 H-Swish CBAM PSPNet in Search and Rescue Scenarios by Di Zhao, Weiwei Zhang, Yuxing Wang

“…In post-disaster search and rescue scenarios, the accurate image segmentation of individuals is essential for efficient resource allocation and effective rescue operations. …”
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Sheffield Adaptive Patterned Electrical Stimulation (SHAPES) Therapy for Post Stroke Arm spasticity: study protocol for a 3-arm, a partially blinded, randomised controlled trial by Ali Ali, Avril D. McCarthy, Mark Reeves, Jamie Healey, Louise Moody, Adewale Adebajo, Tim Good, Simon Dixon, Kathleen Baster, Wendy Tindale, Krishnan Padmakumari Sivaraman Nair

“…Abstract Introduction Post stroke elbow spasticity (PSES) affects over a third of individuals following stroke and negatively impacts on functional recovery, comfort and quality of life. …”
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Pattern of Pulmonary Dysfunctions in Craniovertebral Junction Anomaly and Its Persistence after Rigid Occipitocervical Fixation by Shaam Bodeliwala, Vikas Nagar, Hukum Singh, Daljit Singh, Anita Jagetia, Sharad Pandey, Rajesh Ruttala, Pankaj Kumar

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Abstract 013: Infarct density: a novel imaging biomarker of long‐term functional outcome after endovascular thrombectomy by Christopher G. Favilla, Heta Patel, Mohammad Hossein Abassi, Jesse Thon, Michael T. Mullen, Scott E. Kasner, Jae W. Song, Stephanie Cummings, Steven R. Messe

“…Here we aimed to quantify the relationship between functional outcome and a range of ADC thresholds on post‐EVT MRI. …”
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Understanding oncological and sexual function outcomes with gynaecological organ preserving cystectomy in women with bladder cancer; a systematic review by Rebecca Martin, Harriet Wylie, Charlotte Moss, Shaista Hafeez, Pardeep Kumar, Anne Marie Rafferty, Mieke Van Hemelrijck

“…While SF initially declined, recovery improved over time, with Female Sexual Function Index (FSFI) scores exceeding the 26.2 dysfunction threshold in two studies by 12 months. …”
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