Arginine-loaded mesoporous silica nanoparticles modified 3D-printed nanocomposite denture base resin with improved mechanical and antimicrobial properties by Zixiang Dai, Jiali An, Xiaofeng Huang

“…Data were evaluated by one-way analysis of variance, followed by the Tukey honestly significant difference post hoc test, with a significance level set at 0.05. …”
Get full text

Clinical Efficacy of Mind-Regulating Acupuncture on Post-Stroke Depression Based on the “Microbiota-Gut-Brain Axis” Theory: A Randomized Controlled Study by Xie J, Li J, Sun Q, Jiang J

“…After 8 weeks of treatment, multiple indicators including depression scores, neurological function scores, and levels of neurotransmitters and gut microbiota were compared.Results: MRA significantly improved depressive symptoms, neurological function, and daily living abilities in PSD patients. …”
Get full text

Banxia Gualou Xiebai Tang and Qishen Yiqi Dropping Pills Combined Therapy for Qi Deficiency, Phlegm, and Blood Stasis Syndrome in Post-PCI Coronary Heart Disease Patients by Fan M, Du L, Jiang W, Ding T, Yang X, Peng Z

“…Treatment efficacy, TCM syndrome scores, cardiac function (LVEF, LVEDD, LVESD, CO), blood lipids (TC, TG, HDL-C, LDL-C), hemorheological parameters (PV, Hct, HSBV, LSBV), and adverse events were compared.Results: ① The total effective rate in the observation group (92.0%) was significantly higher than in the control group (76.0%) (P< 0.05). ② TCM syndrome scores significantly improved in both groups, with greater improvement in the observation group at 3 and 6 months (P< 0.05). ③ Cardiac function: LVEF and CO increased, while LVEDD and LVESD decreased in both groups, with more significant changes in the observation group (P< 0.05). ④ Blood lipids: TC, TG, and LDL-C decreased, and HDL-C increased in both groups, with greater changes in the observation group (P< 0.05). ⑤ Hemorheology: PV, Hct, HSBV, and LSBV decreased more in the observation group (P< 0.05). ⑥ Adverse events: The observation group had a higher incidence of adverse events (22.0% vs 14.0%, P< 0.05).Conclusion: Banxia Gualou Xiebai Tang combined with Qishen Yiqi Dropping Pills, alongside standard treatment, significantly improves efficacy, cardiac function, hemorheology, and blood lipids in post-PCI CHD patients without increasing adverse events.Keywords: banxia gualou xiebai tang, qishen yiqi dropping pills, coronary heart disease, PCI, Qi deficiency, phlegm, blood stasis syndrome, efficacy…”
Get full text

Luteolin reduces necroptosis in the diabetic heart after cardiac arrest and resuscitation by activating sirtuin 3 by Jin-Ting Yang, Chun-Yan Jiang, Zi-Yan Zhang, Li-Hui Tang, Yang-Yun Lou, Ling-Bo Qian

“…After 6 h of resuscitation, left ventricular function, myocardial infarction, oxidative stress markers, inflammatory cytokine release, mitochondrial function, necroptosis-associated protein expression, and both Sirt3 expression and enzymatic activity were assessed.ResultsLuteolin significantly improved post-resuscitation cardiac function and reduced myocardial infarction, oxidative stress, and pro-inflammatory cytokine levels in diabetic rats. …”
Get full text

‎‌The‌‎ ‎‌effect‌‎ ‎‌of‌‎ ‎‌eight‌‎ ‎‌weeks‌‎ ‎‌of‌‎ ‎‌perceptual‌‎-‎‌motor‌‎ ‎‌exercises‌‎ ‎‌on‌‎ ‎‌executive‌‎ ‎‌functions‌‎ ‎‌and‌‎ ‎‌the‌‎ ‎‌development‌‎ ‎‌of‌‎ ‎‌fundamental‌... by Yones‏‎ Anbari‏‎, ‎‏Farzad Mohammadi, ‎‏Negar Salehi‏‎ ‎‏Mobarakeh

“…‎‏Background‏‎ ‎‏and‏‎ ‎‏aims‏‎: ‎‏Children‏‎ ‎‏with‏‎ ‎‏intellectual‏‎ ‎‏disabilities‏‎ ‎‏often‏‎ ‎‏experience‏‎ ‎‏deficits‏‎ ‎‏in‏‎ ‎‏executive‏‎ ‎‏functions‏‎ ‎‏and‏‎ ‎‏motor‏‎ ‎‏skills.‏‎ ‎‏This‏‎ ‎‏study‏‎ ‎‏aimed‏‎ ‎‏to‏‎ ‎‏investigate‏‎ ‎‏the‏‎ ‎‏impact‏‎ ‎‏of‏‎ ‎‏perceptual‏‎-‎‏motor‏‎ ‎‏exercises‏‎ ‎‏on‏‎ ‎‏improving‏‎ ‎‏both‏‎ ‎‏executive‏‎ ‎‏functions‏‎ ‎‏and‏‎ ‎‏the‏‎ ‎‏development‏‎ ‎‏of‏‎ ‎‏fundamental‏‎ ‎‏motor‏‎ ‎‏skills‏‎ ‎‏in‏‎ ‎‏children‏‎ ‎‏with‏‎ ‎‏intellectual‏‎ ‎‏disabilities.‏‎ ‎‏…”
Get full text

The joint effects of inflammation and renal function status on in-hospital outcomes in patients with acute ischemic stroke treated with intravenous thrombolysis by Zhichao Huang, Xiaoyue Zhu, Xiuman Xu, Yi Wang, Yafang Zhu, Dongqin Chen, Yongjun Cao, Xia Zhang

“…Similarly, when we added CRP and eGFR to the basic model with conventional risk factors, the risk discrimination and prediction for post-stroke pneumonia and functional outcome was also significantly improved. …”
Get full text

Transplanting intact donor tissue enhances dopamine cell survival and the predictability of motor improvements in a rat model of Parkinson's disease. by Rosemary A Fricker, Jan Herman Kuiper, Monte A Gates

“…D-amphetamine- induced rotations revealed that animals receiving pieces of VM tissue or dissociated cells showed significant improvement in ipsilateral rotation 4 weeks post transplantation. …”
Get full text

Hand Function Recovers to Near Normal in Patients with Deep Dermal Hand Burns Treated with Enzymatic Debridement: A Prospective Cohort Study by Kelly Aranka Ayli Kwa, Annika Catherina Reuvers, Jorien Borst-van Breugel, Anouk Pijpe, Paul P. M. van Zuijlen, Roelf S. Breederveld, Annebeth Meij-de Vries

“…Short- and long-term hand function was evaluated in adult patients with deep dermal and full-thickness hand burns after treatment with enzymatic debridement (NexoBrid^® MediWound Ltd., Yavne, Israel), assessing the results at discharge and 3, 6, and 12 months post-burn. …”
Get full text

Nifedipine and losartan effects on endothelial function during acute pharmacological test in arterial hypertension patients with various risk factors by M. O. Argunova, A. G. Avtandilov

Get full text

Effects of oral lycopene supplementation on vascular function in patients with cardiovascular disease and healthy volunteers: a randomised controlled trial. by Parag R Gajendragadkar, Annette Hubsch, Kaisa M Mäki-Petäjä, Martin Serg, Ian B Wilkinson, Joseph Cheriyan

“…At baseline, CVD patients had impaired EDV compared with HV (30% lower; 95% CI: -45% to -10%, P = 0.008), despite lower LDL cholesterol (1.2 mmol/L lower, 95% CI: -1.6 to -0.9 mmol/L, P<0.001). Post-therapy EDV responses for lycopene-treated CVD patients were similar to HVs at baseline (2% lower, 95% CI: -30% to +30%, P = 0.85), also suggesting lycopene improved endothelial function.…”
Get full text

Efficacy of Nusinersen Treatment in Type 1, 2, and 3 Spinal Muscular Atrophy: Real-World Data from a Single-Center Study by Anna Lemska, Piotr Ruminski, Jakub Szymarek, Sylwia Studzinska, Maria Mazurkiewicz-Beldzinska

“…SMA is classified into types 0 through 4 based on the age of symptom onset and the severity of motor function decline. Recent advances in SMA treatment, including nusinersen, onasemnogene abeparvovec, and risdiplam, have significantly improved the prognosis of SMA patients. …”
Get full text

Ambulatory Catheter-based Interscalene Block for Proximal Humerus Fracture Rehabilitation: Safety, Efficacy and Lessons from a Pilot Study by Nah MFK, Seng ZQ, Tan YJB

“…Introduction: Proximal humerus fractures (PHFs) are associated with morbidity/functional impairment. Rehabilitation adherence is crucial to regain independent function yet is often hindered by pain. …”
Get full text

Effect of family-oriented interviews on family function of young persons attending the family practice clinic in Oauthc, Ile Ife, south-western Nigeria by Akinjide O. Ogundokun, Emmanuel A. Abioye-Kuteyi, Ibrahim S. Bello, Olanrewaju O. Oyegbade, Samuel A. Olowookere, Akintunde J. Olowookere

“…Family-oriented interview may have significantly improved perceived family function in the study. Family-oriented interview of young persons presenting for medical care is recommended.…”
Get full text

Clopidogrel Versus Aspirin as Chronic Maintenance Antiplatelet Monotherapy in Patients After Percutaneous Coronary Intervention With Chronic Kidney Disease: A Post Hoc Analysis of... by Jeehoon Kang, Sang‐Hyeon Park, Kyung Woo Park, Bon‐Kwon Koo, Huijin Lee, Minju Han, Doyeon Hwang, Han‐Mo Yang, In‐Ho Chae, Won‐Yong Shin, Ju Hyeon Oh, Yong Hoon Kim, Tae‐Ho Park, Bum Soo Kim, Jung‐Kyu Han, Eun‐Seok Shin, Hyo‐Soo Kim

“…However, it is uncertain whether the beneficial effect of clopidogrel over aspirin is different according to the renal function. Methods and Results We conducted a post hoc analysis of the HOST‐EXAM trial. …”
Get full text

The effect of preoperative oral carbohydrate administration on postoperative glucometabolic response, subjective well being and quality of life in patients undergoing colorectal su... by Murat Urkan, Cemile Celebi, Ulvi Mehmet Meral, Ikbal Cavdar

Get full text

Baseline Motor Impairment Predicts Transcranial Direct Current Stimulation Combined with Physical Therapy-Induced Improvement in Individuals with Chronic Stroke by Adriana Baltar, Daniele Piscitelli, Déborah Marques, Lívia Shirahige, Kátia Monte-Silva

“…A backward stepwise regression was used to assess the effect of age, sex, time since stroke, brain lesion side, and basal level of motor function on UE-FM improvement after treatment. Following the intervention, UE-FM significantly improved (p<0.05), and the magnitude of the change was clinically important (mean 6.2 points, 95% CI: 5.2–7.4). …”
Get full text

Quick sequential organ failure assessment score combined with other sepsis-related risk factors to predict in-hospital mortality: Post-hoc analysis of prospective multicenter study... by Ryo Ueno, Takateru Masubuchi, Atsushi Shiraishi, Satoshi Gando, Toshikazu Abe, Shigeki Kushimoto, Toshihiko Mayumi, Seitaro Fujishima, Akiyoshi Hagiwara, Toru Hifumi, Akira Endo, Takayuki Komatsu, Joji Kotani, Kohji Okamoto, Junichi Sasaki, Yasukazu Shiino, Yutaka Umemura

“…Other key statistic values were similar among all models, with sensitivity and specificity of 0.55-0.65 and 0.60-0.75, respectively. In this post-hoc data analysis from a prospective multicenter study based in Japan, combining qSOFA with other sepsis-related risk factors only marginally improved the model's predictive value.…”
Get full text

Clinical effect of Yishen Huashi Granules combined with conventional Western medicine on stage 2-4 chronic kidney disease by Zhou Huan, Li Jing, Xiao Xiao-fen, He Yong, Zhang Xin, Zhang Ying, Wang Xiao-hui

“…Subgroup analyses showed that renal function indexes were significantly improved after treatment in G2-3a and G3b-4 subgroups （<italic>P</italic>&lt;0.05）， and their improvements were superior than the control group （<italic>P</italic>&lt;0.05）. . …”
Get full text

The Impact of Sports Vision Training Under Manipulated Lighting Conditions on Static and Functional Balance and Fear of Falling in Older Adults by Pardis Pourkhosravani, Maryam Kavyani, Mahin Aghdaei

“…In both pre- and post-test phases, the berg balance scale test for static balance and timed up & go (TUG) test for functional balance were conducted under low and normal lighting conditions. …”
Get full text

Impact of precision nursing intervention based on DCO model on joint function and quality of life of elderly hip arthroplasty patients by Junyan Cui, Yuhong Liang, Yanfei Wang, Fangling Guo, Di Yang, Yuting Liao

“…Results Compared to pre-intervention, the hip joint function scores and BI scores in both groups significantly improved post-intervention, with the observation group scoring higher than the control group (P < 0.05). …”
Get full text