KArAT (Knee Arthroplasty Activity Trial): Rationale and design features of a multicenter randomized controlled trial by Elena Losina, Jamie E. Collins, Mahima Kumara, Linda Ehrlich-Jones, Maame Opare-Addo, Clare Safran-Norton, Neil A. Segal, Lauren M. Mitchell, Paul T. Kopp, Faith Selzer, Hanna Mass, Michael Paskewicz, Rowland W. Chang, Dorothy Dunlop, Antonia F. Chen, Samuel Lerner, Samantha Chin, Christine Pellegrini, Jeffrey N. Katz

“…Despite substantial pain reduction and functional improvements, physical activity (PA) does not necessarily increase post TKA. …”
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Reconstitution of T cell‐mediated immunity by umbilical cord‐derived mesenchymal stem cells in ulcerative colitis by Xiaoying Luo, Jieping Deng, Xiaoke Jiang, Jun Mi, Yangqiu Bai, Huimin Zhang, Yalong Li, Min Liu, Conghui Cai, Pengju Li, Huanrong Huang, Yueping Xu, Yiwen Qin, Yang Mi, Hui Ding, Zhiyu Yang, Yue Wu, Zhenjuan Li, Ling Lan, Lida Zhang, Li Wang, Guobing Chen, Han Yue, Oscar Junhong Luo, Bingyong Zhang

“…The 26 enrolled patients were administered two UMSC doses intravenously. Pre‐ and post‐therapy colon biopsy specimens were analysed by single‐cell RNA sequencing (scRNA‐seq). …”
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The design of a context-aware service system in intelligent transportation system by Jingkun Chang, Wenbin Yao, Xiaoyong Li

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Gamma Knife stereotactic radiotherapy combined with tislelizumab as later-line therapy in pMMR/MSS/MSI-L metastatic colorectal cancer: a phase II trial analysis by Yiran Zhang, Hanyang Guan, Shijin Liu, Haoquan Li, Zili Bian, Jiashuai He, Zhan Zhao, Shenghui Qiu, Tianmu Mo, Xiangwei Zhang, Zuyang Chen, Hui Ding, Xiaoxu Zhao, Liang Wang, Yunlong Pan, Jinghua Pan

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Effectiveness of Blended Internet-based Self-help and Face-to-face Intervention for Depression: A Pilot Study from India by Sindhuja Sudarshan, Seema Mehrotra, Jagadisha Thirthalli

“…Conclusion: The blended intervention demonstrated effectiveness in reducing depression and improving self-esteem, and functional and psychological recovery.…”
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The lactylation modification of proteins plays a critical role in tumor progression by Dehao Yi, Ke Zhou, Yinlong Pan, Huazhong Cai, Pan Huang, Pan Huang

“…Lactylation modifications have been shown to be a novel type of protein post-translational modifications (PTMs), providing a new perspective for understanding the interaction between cellular metabolic reprogramming and epigenetic regulation. …”
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Progress on characteristics and application of yeasts and its derivatives in fruit wine brewing by FENG Jun, FENG Xiaohong, LI Ke, TIAN Xinhui, YUAN Jie, ZHAO Xingtong, HE Junyao, LIU Yao

“…The yeast derivatives can enhance the yeast vitality and fermentation efficiency in the fermentation stage of fruit wine, promote the coordination of the wine body and improve sensory quality in the post-fermentation stage. …”
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Prevention and treatment of cerebral vasospasm following aneurysmal subarachnoid hemorrhage by Kyle McGrath, Grace Hey, Ghaidaa Ebrahim, Noah Gilberstadt, David Mahan, Brandon Lucke-Wold

“…Future trials of these therapies and combinations of existing therapies are needed, and functional outcomes should be included as an endpoint. …”
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Relationships Matter Most: A Mixed Methods Study into Meaning in Life in Personality Disorder, Before and After Treatment by Angelien Steen, Pauline Sam, Carmen Schuhmann, Arjan W. Braam

“…Here, addressing interpersonal functioning represents a key element, probably by improving connectedness with loved ones.…”
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Fitts’ law-based identification of motor development stages for the upper limb: proof of concept in three age groups by Cristina Sanchez, Eloy Urendes, Alejandra Aceves, María Martínez-Olagüe, Rafael Raya

“…This process is closely tied to neurological maturation, with “reaching and pointing tasks” considered fundamental upper limb functions. According to Fitts’ law, movement time (MT) depends on the task’s index of difficulty (ID). …”
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Promoting sleep and mental well-being in children: Protocol for a naturalistic pilot in-app study among users of the Aumio app. by Nadja Ruckser, Melissa Röcken, Jean Ochel, Alfred Wiater, Claudia Calvano

“…Sleep problems are widespread among children and can have a negative impact on their development, everyday functioning and pose an additional burden on the parents. …”
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Pemberdayaan Masyarakat Muda Sekolah Melalui Upaya Penerapan Mitigasi dan Tanggap Darurat Bencana by Esi Afriyanti, Nofrizon Nofrizon, Rika Fatmadona, Emil Huriani, Fitri Mailani, Boby Febri Krisdianto, Rahmi Muthia, Devia Putri Lenggogeni, Leni Merdawati

“…Schools play an important role and have several functions in disaster risk reduction including facilitating and cooperating with the surrounding environment, improving community skills, refugee centers when disaster strikes. …”
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Use of client-centered virtual reality in rehabilitation after stroke: a feasibility study by Alberto Luiz Aramaki, Rosana Ferreira Sampaio, Alessandra Cavalcanti, Fabiana Caetano Martins Silva e Dutra

“…In the interviews, the participants described their post-stroke difficulties; how the video game motivated their engagement in rehabilitation; and the improvement of occupational performance and social participation after participating in the program. …”
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The Subjective and Objective Evaluation of the Efficacy of Public Spaces in University Complexes: A Case Study of the Center for Balance Architecture at Zhejiang University by Linfeng Yao, Danshen Dong, Yuxi He, Jing Wang

“…Our results reveal significant post-renovation improvements in spatial accessibility, particularly in terms of First Floor Plan connectivity. …”
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Extracting Realistic Pedestrian, Cycling, and Driving Street Networks from OpenStreetMap by J. P. Duque, M. A. Brovelli

“…The methodology also offers an assessment functionality to identify potential inconsistencies in OSM extracted networks, providing support for mapping campaigns seeking to improve its quality. …”
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Understanding the impact of diabetes on bone health: A clinical review by Preeti Sharma, Rahul Kumar Sharma, Khushboo Gaur

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INSTITUTIONAL DETERMINANTS OF NON-PERFORMING LOANS OF DEPOSIT MONEY BANKS IN SUB-SAHARAN AFRICA by Olusegun Opeyemi Oni, Henry Jonathan

“…The study therefore, recommended among others, that government of Sub-Saharan Africa countries need to adopt effective legal restructuring with respect to bad loans, improve the functioning of their regulatory bodies, reduce corruption and government interference in banking businesses so as to decline the issues of NPLs …”
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Explainable data mining model for hyperinsulinemia diagnostics by Nevena Rankovic, Dragica Rankovic, Mirjana Ivanovic, Igor Lukic

“…Unlike standard Principal Component Analysis (PCA), which is sensitive to the initial positions of cluster centers influencing the final outcome, our model integrates FPCA with K-Means clustering to improve the preprocessing stage. Additionally, we have incorporated the post-hoc explanatory method SHAP (SHapley Additive exPlanations) alongside algorithms such as Random Forest, XGBoost, and LightGBM to provide deeper insights into our model, identifying the most contributory features for the development of hyperinsulinemia. …”
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An Observational Study on Pre-natal Diagnosis of Congenital Talipes Equinovarus by Gaurav Vatsa, Saurabh Suman, Siddharth Kumar Singh

“…Participants underwent anomaly scans, with fetal lower limbs assessed for clubfoot indicators. Follow-up included post-natal examinations and Pirani scoring for confirmed cases. …”
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Development of an Augmented Reality-Integrated Student Worksheet (LKPD) to Enhance Mathematics Learning Outcomes by Sri Murni Hidayani, Arif Muchyidin, Arif Abdul Haqq

“…Future research should focus on improving AR functionality for broader accessibility. …”
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