In-depth analysis of the safety of CAR-T cell therapy for solid tumors by Jiayi Dong, Jiayi Dong, Jiayi Dong, Jiayi Dong, Jiexiong Wu, Ye Jin, Ye Jin, Ye Jin, Ye Jin, Ye Jin, Zhu Zheng, Zhu Zheng, Zhu Zheng, Zhu Zheng, Zhu Zheng, Ting Su, Ting Su, Ting Su, Ting Su, Ting Su, Lijuan Shao, Lijuan Shao, Lijuan Shao, Lijuan Shao, Lijuan Shao, Jiaxin Bei, Jiaxin Bei, Jiaxin Bei, Jiaxin Bei, Size Chen, Size Chen, Size Chen, Size Chen, Size Chen

“…It typically occurs within the first week post-infusion, correlating with CAR-T cell expansion and often presents with fever and hypotension. …”
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Health perceptions of older individuals on the cognitive benefits of a multicomponent green physical activity program: A qualitative exploration in the Southwest Region of Bahia, B... by Carolina Rego Chaves Dias, Saulo Vasconcelos Rocha, Milena Fernandez Dias, Bruno Morbeck de Queiroz, Natália Nascimento Silva, Ariani França Conceição, Bruna Maria Palotino-Ferreira, Sonia Brito-Costa, Sofia de Lurdes Rosas da Silva, Clarice Alves dos Santos, Lélia Renata Carneiro Vasconcelos, Guilherme Eustáquio Furtado

“…Background and aims: A multicomponent exercise program (MEP) is a tailored, physical activity-based intervention that incorporates several exercise modalities to improve physical function and reduce negative health consequences, such as cognitive decline. …”
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Perampanel for alleviation of secondary injury in traumatic brain injury (PEACE-TBI): a protocol for a phase-II multicentre randomised clinical trial by Ryota Tamura, Yuki Kuranari, Yukina Morimoto, Masahiro Toda, Tokunori Kanazawa, Makoto Inaba, Ryo Yamamoto, Koichiro Homma, Takahiro Shoji, Junichi Sasaki, Masayuki Shimizu, Masato Nakaya, Satoshi Terao, Ryota Sasao, Makoto Katayama, Koichi Ueno, Yumiko Oishi, Akiyoshi Nakamura, Yo Kikuo, Ryosuke Murakami, Sota Wakahara, Konosuke Ishikawa, Kenzo Kosugi, Tatsuro Ozaki

“…Although no medication has been validated yet to prevent secondary injury of brain tissue, recent animal studies have reported that perampanel, a glutamine receptor antagonist, could improve the neurological functions of animals with TBI by mitigating the abnormal calcium influx and cell death around the site of primary injury. …”
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Ashwagandha (Withania somnifera (L.) Dunal) for promoting recovery in long covid: protocol for a randomised placebo-controlled clinical trial (APRIL Trial) by Kamlesh Khunti, Shailen Sutaria, Poppy Alice Carson Mallinson, Sanjay Kinra, Rohini Mathur, Anoop SV Shah, Tim Clayton, Judith Lieber, Alexander Perkins, Shereen Allaham, Nick Birk, Lily Hopkins, Manisha Joshi, Mahesh Mathpathi, Arandeep Dhillon, Sidra S Beg, Archie Khan, Vanessa TW Kam, Galib R, S Rajagopala, Amarjeet Bhamra, Geetha Krishnan G Pillai, Tanuja Nesari

“…The primary outcome of the Post-COVID Functional Status Scale score at 3 months will be assessed by baseline-adjusted ordinal logistic regression, according to a pre-published statistical analysis plan. …”
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Bisoprolol for patients with chronic obstructive pulmonary disease at high risk of exacerbation: the BICS RCT by Graham Devereux, Seonaidh Cotton, Mintu Nath, Nicola McMeekin, Karen Campbell, Rekha Chaudhuri, Gourab Choudhury, Anthony De Soyza, Shona Fielding, Simon Gompertz, John Haughney, Amanda Lee, Graeme MacLennan, Alyn Morice, John Norrie, David Price, Philip Short, Jorgen Vestbo, Paul Walker, Jadwiga Wedzicha, Andrew Wilson, Olivia Wu, Brian Lipworth

“…Total number of major adverse cardiovascular events. Lung function (NB, during the COVID-19 pandemic, lung function could not be assessed in participants). …”
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The Effect of Different Levels of CLA and Omega-3 Supplements Along with Essential Oils of Fennel, Peppermint, and Eucalyptus Medicinal Plants on Production Performance, Blood Para... by Yadollah Chashnidel, Matin Movagharnezhad, Mehdi Jafary charati

“…The overall results showed that the high level of CLA and Omega-3 supplements together with medicinal plants could improve the functional traits of laying hens of the Lehman breed. …”
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Hardcoded vulnerability detection approach for IoT device firmware by Chao MU, Xin WANG, Ming YANG, Heng ZHANG, Zhenya CHEN, Xiaoming WU

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Primary osteosarcoma of the breast during lactation: a case report and literature review by Huifang Zhuo, Huifang Zhuo, Yubei Duan, Shuangshuang Dong, Shuangshuang Dong, Jun Zhang, Jun Zhang, Zijing Wang, Zijing Wang, Lian Meng, Lian Meng, Chenyan Wang, Man Li, Xiaotian Yang, Ning Wang, Ning Wang, Jianming Hu

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Purification of Phycocyanin from Spirulina platensis Using Natural Deep Eutectic Solvents with Varied Hydrogen Bond Donor by Eirene Tentua, Safrina Dyah Hardiningtyas, Iriani Setyaningsih

“…Phycocyanin retained its structural integrity, with enhanced antioxidant activity (IC50 = 40.54 ppm) post-purification. The aqueous two-phase system (ATPs) efficiently separated impurities, improving extraction scalability. …”
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Co-modulation of a circular form of PCDH11Y during neuroendocrine differentiation of prostate cancer by Giovanni Pecoraro, Ilaria Leone, Silvia Nuzzo, Santiago Negueruela, Giovanni Smaldone, Lorena Buono

“…To achieve that, we applied CirComPara2 pipeline to publicly available datasets to identify the differently expressed circRNAs in the LNCaP cell lines pre- and post-transdifferentiation. After that, validation and functional analysis by RNA-interference was applied to a selected circRNA to explore its role during NED. …”
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Narrative Review on the Management of Neck of Femur Fractures in People Living with HIV: Challenges, Complications, and Long-Term Outcomes by Yashar Mashayekhi, Chibuchi Amadi-Livingstone, Abdulmalik Timamy, Mohammed Eish, Ahmed Attia, Maria Panourgia, Dushyant Mital, Oliver Pearce, Mohamed H. Ahmed

“…Despite the rising global prevalence of PLWHIV, no specific guidelines exist for the perioperative and post-operative care of PLWHIV undergoing NOF fracture surgery. …”
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Machine learning cluster analysis identifies increased 12-month mortality risk in transcatheter aortic valve replacement recipients by Thomas Meredith, Thomas Meredith, Thomas Meredith, Farhan Mohammed, Amy Pomeroy, Sebastiano Barbieri, Sebastiano Barbieri, Erik Meijering, Louisa Jorm, David Roy, Jason Kovacic, Jason Kovacic, Jason Kovacic, Jason Kovacic, Michael Feneley, Michael Feneley, Michael Feneley, Christopher Hayward, Christopher Hayward, Christopher Hayward, David Muller, David Muller, David Muller, Mayooran Namasivayam, Mayooran Namasivayam, Mayooran Namasivayam

“…Our results highlight the utility of machine learning applications for clinical risk prediction and scope to improve patient surveillance.…”
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F-box/LRR-repeat protein 12 reorchestrated microglia to inhibit scarring and achieve adult spinal cord injury repair by Xu Xu, Feng Gao, Qixin Chen, Bairu Chen, Wenyu Liang, Runzhi Huang, Yuchen Liu, Zhibo Liu, Yanjing Zhu, Gufa Lin, Bei Ma, Letao Yang, Shaorong Gao, Rongrong Zhu, Liming Cheng

“…Importantly, axons grew through the epicenter and reached a length of more than 2.4 mm 56 days post-SCI, significantly improving motor function and reconstructing the neural circuit. …”
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L’inadéquation entre l’offre et la demande d’éducation au Nord Cameroun : le cas du Département du Logone- et- Chari by Collins Etienne Kana

“…With the aim of attaining the Millennium Development Goals (MDGs) and recently the post 2015 Sustainable Development Goals (SDGs), significant efforts have been made since 2000 in the Cameroonian context. …”
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The role of physical exercise in the rehabilitation of children with surgically treated unilateral slipped capital femoral epiphysis by Marius Negru, Liliana Catan, Elena Amaricai, Adrian Emil Lazarescu, Marius Rezumes, Corina Maria Stanciulescu, Eugen Sorin Boia, Calin Marius Popoiu

“…The main objective of our study is to underline the im-portance of early rehabilitation in functional recovery of children with operated unilateral SCFE. 30 patients with unilateral SCFE treated by in situ fixation with a percutaneous screw have been evaluated using the Harris Hip Score (HHS) before surgery, 7 days post-op and three months post-operatively. …”
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ANXIETY AND DEPRESSION DIAGNOSTIC METHODS IN PATIENTS WITH ACUTE MYOCARDIAL INFARCTION by V. A. Lusov, N. A. Volov, A. Yu. Lebedeva, M. A. Benevskaya, M. A. Kudinova

“…Depressive disorders, accompanying acute myocardial infarction, affect clinical course in post-infarction phase, patients’ functioning and quality of life. …”
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Differentially expressed microRNAs in pre-transplant lung biopsies target immune checkpoint proteins and can predict primary graft dysfunction in lung transplantation by Vitale Miceli, Pia Ferrigno, Claudio Centi, Claudia Carcione, Gioacchin Iannolo, Valentina Agnese, Giovanna Lo Iacono, Rosa Liotta, Pier Giulio Conaldi, Massimo Pinzani, Lavinia De Monte, Alessandro Bertani

“…Lung transplantation (LTx) significantly improves outcomes for patients with end-stage respiratory failure. …”
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Efficacy of Chinese Medicine on Postoperative Rehabilitation of Non-small Cell Lung Cancer (NSCLC), a Randomized Controlled Study by Yifeng Gu MD, Yichao Wang MD, Huiling Zhou MD, Ao Qi PhD, Guanjin Wu MM, Jiaqi Li MMed, Congmeng Zhang MMed, Yong Yang MD, Jialin Yao MD, Wenxiao Yang PhD, Lingzi Su MMed, Yi Liu MMed, Xueqi Tian MMed, Jiajun Song MMed, Yabin Gong MD, Xiong Qin MD, Lijing Jiao PhD, Ling Xu PhD

“…The intervention group showed better post-treatment SF-36 scores in Role-Physical (RP), Social Function (SF), Role-Emotional (RE), and Mental Health Summary (MCS) ( P  < .05). …”
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A first-in-human, prospective pilot trial of umbilical cord-derived mesenchymal stem cell eye drops therapy for patients with refractory non-Sjögren's and Sjögren's syndrome dry ey... by Di Zhang, Taige Chen, Qi Liang, Xuebing Feng, Jiaxuan Jiang, Zeying Chen, Yun Tang, Yiran Chu, Bin Wang, Kai Hu

“…Secondary assessments focused on the evaluation of lipid layer, meibomian gland function, and bulbar conjunctival redness. Safety was monitored by recording adverse events (AEs) throughout the study. …”
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How reliable is the labeling of a commercial phytosteroid product? A 12-week randomized double-blind training study by Joshua Dissemond, Tim Havers, Steffen Held, Stephan Geisler, Tihomir Kostov, Patrick Diel, Svea Türschmann, Maria K. Parr, Eduard Isenmann

“…M. vastus lateralis and M. vastus intermedius). Liver and kidney function, along with endocrine parameters, were measured via blood samples pre- and post-intervention. …”
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