Targeting Immunoproteasome in Polarized Macrophages Ameliorates Experimental Emphysema Via Activating NRF1/2‐P62 Axis and Suppressing IRF4 Transcription by Bingxin Guo, Xing Shi, Qiong Jiang, Yuanwei Pan, Yuqiong Yang, Yuanyuan Liu, Shuyu Chen, Wenjiao Zhu, Laibin Ren, Ruifang Liang, Xue Chen, Haizhao Xu, Laiyou Wei, Yongjian Lin, Jinyong Wang, Chen Qiu, Haibo Zhou, Lang Rao, Lingwei Wang, Rongchang Chen, Shanze Chen

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A Proteome-Level Investigation Into Plasmodiophora brassicae Resistance in Brassica napus Canola by Dinesh Adhikary, Devang Mehta, R. Glen Uhrig, Habibur Rahman, Nat N. V. Kav

“…Root samples were collected at three distinct stages of pathogenesis, 7−, 14−, and 21-days post inoculation (DPI), protein samples were isolated, digested with trypsin and subjected to liquid chromatography with tandem mass spectrometry (LC-MS/MS) analysis. …”
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Possibilities of Combination of Beta-blockers and Ivabradine in Patients with Stable Angina Pectoris by V. V. Kashtalap, O. L. Barbarash, D. Yu. Sedykh, K. E. Krivoshapova, D. P. Tsygankova, O. V. Tsygankova

“…A prospective observational post-registration study was performed at the Research Institute for Complex Issues of Cardiovascular Diseases. …”
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Epithelial stem cells from human small bronchi offer a potential for therapy of idiopathic pulmonary fibrosisResearch in context by Zeyu Liu, Qi Zheng, Zhoubin Li, Moli Huang, Cheng Zhong, Ruize Yu, Rong Jiang, Haotian Dai, Jingyuan Zhang, Xiaohua Gu, Yongle Xu, Chunwei Li, Shan Shan, Feng Xu, Yue Hong, Tao Ren

“…Autologous BCs transplantation in three advanced IPF patients with small airway dysfunction yielded significant clinical improvements in pulmonary function, particularly evidence in lung volume and small airway function. …”
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The Role of IL-6 and TNF-Alpha Biomarkers in Predicting Disability Outcomes in Acute Ischemic Stroke Patients by Ciprian-Ionuț Băcilă, Maria-Gabriela Vlădoiu, Mădălina Văleanu, Doru-Florian-Cornel Moga, Pia-Manuela Pumnea

“…Introduction: Inflammatory biomarkers, including Interleukin-6 (IL-6) and Tumor Necrosis Factor-alpha (TNF-alpha), play a significant role in influencing stroke outcomes, particularly in the progression of post-stroke disability. While numerous studies have suggested a correlation between elevated levels of these cytokines and poor functional recovery, further investigation is needed to understand their prognostic value in acute ischemic stroke. …”
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Mindfulness vs. sleep education during autologous hematopoietic cell transplantation for multiple myeloma: Feasibility of a randomized controlled pilot study by Elisabeth C. Henley, Hannah A. Liphart, Keayra J. Morris, Iwalola Awoyinka, Michael R. Irwin, Erin S. Costanzo, Diana Winston, Anita D'Souza, Melinda Stolley, Binod Dhakal, Meera Mohan, Marcelo C. Pasquini, Steven W. Cole, Erin S. Doerwald, Peyton C. Bendis, Kelly E. Rentscher, Meredith E. Rumble, Aniko Szabo, Sridhar Rao, Jennifer M. Knight

“…Mindfulness-based interventions (MBIs) can improve sleep quality during and following cancer treatment by reducing treatment-related symptoms and enhancing immune function. …”
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Effects of fermented Arctium lappa L. root by Lactobacillus casei on hyperlipidemic mice by MingJu Chen, Yuxiao Wu, Hongxuan Yang, Tianfeng Liu, Tongkun Han, Wangqiang Dai, Junyue Cen, Fan Ouyang, Jingjing Chen, Jianxin Liu, Lin Zhou, Xuguang Hu

“…In vitro antioxidant activity, liver injury, lipid levels, pro-inflammatory cytokine levels, and cholesterol-related mRNA expression were assessed. 16S rRNA sequencing was conducted to evaluate changes in gut microbiota composition.ResultsLC-AR exhibited stronger antioxidant activity and higher metabolite levels than AR. It also improved liver injury as well as better regulation of lipid levels, pro-inflammatory cytokine levels, and cholesterol-related mRNA. 16S rRNA analysis revealed that LC-AR decreased the Firmicutes/Bacteroidetes ratio, which correlated negatively with triglycerides, total cholesterol, and low-density lipoprotein cholesterol levels.DiscussionThese findings suggest that LC-AR may serve as a promising functional food and drug raw material for improving hyperlipidemia, particularly through its beneficial effects on gut microbiota and lipid regulation.…”
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A biomechanical pilot case study on the effect of spinal fusion surgery on gait loading asymmetry in scoliosis patients by Sadiq J. Hamandi, Hamza Abbas, Basma A. AlGhali, Safaa K. Alhussainy

“…Post-operative therapy is recommended to restore kinetic balance and functional gait.…”
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Characterization and z-score calculation of cardiovascular magnetic resonance imaging parameters in patients after the Fontan operation: A Fontan Outcome Registry using Cardiovascu... by Tarek Alsaied, Runjia Li, Adam B. Christopher, Mark Fogel, Timothy C. Slesnick, Rajesh Krishnamurthy, Vivek Muthurangu, Adam L. Dorfman, Christopher Z. Lam, Justin D. Weigand, Jong-Hyeon Jeong, Joshua D. Robinson, Laura J. Olivieri, Rahul H. Rathod, Yue-Hin Loke, Kenan Stern, Jonathan H. Soslow, Manish Aggarwal, Tiffanie Johnson, Markus Renno, Amee Shah, Michael Quail, Shelby Kutty, Ruchira Garg, Jeremy Steele, Pierangelo Renella, Madhuradhar Chegondi, Aswathy Vaikom House, Alison Marsden, Francesca Raimondi

“…ABSTRACT: Background: Cardiac magnetic resonance (CMR) offers valuable hemodynamic insights post-Fontan, but is limited by the absence of normative single ventricle data. …”
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Pramipexole in addition to mood stabilisers for treatment-resistant bipolar depression: the PAX-BD randomised double-blind placebo-controlled trial by Hamish McAllister-Williams, Nicola Goudie, Lumbini Azim, Victoria Bartle, Michael Berger, Chrissie Butcher, Thomas Chadwick, Emily Clare, Paul Courtney, Lyndsey Dixon, Nichola Duffelen, Tony Fouweather, William Gann, John Geddes, Sumeet Gupta, Beth Hall, Timea Helter, Paul Hindmarch, Eva-Maria Holstein, Ward Lawrence, Phil Mawson, Iain McKinnon, Adam Milne, Aisling Molloy, Abigail Moore, Richard Morriss, Anisha Nakulan, Judit Simon, Daniel Smith, Bryony Stokes-Crossley, Paul Stokes, Andrew Swain, Zoë Walmsley, Christopher Weetman, Allan H Young, Stuart Watson

“…Secondary analysis indicated significant improvements in psychosocial function at 36 and 48 weeks. …”
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A comprehensive evaluation of the transition to a biosimilar of adalimumab in rheumatoid arthritis and psoriatic arthritis: a single-center experience with a focus on imaging outco... by Rodrigo Garcia-Salinas, Sebastian Magri, Alvaro Ruta, Santiago Ruta

“…In this analysis of the switch between oADA and bADA, no differences were found in disease activity, functional capacity, or radiographic progression. Ultrasonography indicated improvement of PD findings. …”
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Cardiomyocyte-specific NHE1 overexpression confers protection against myocardial infarction during hyperglycemia by Kai Jiang, Fanghua Su, Ruhua Deng, Yue Xu, Anqi Qin, Xun Yuan, Dongmei Xing, Yang Chen, Dandan Wang, Lan Shen, John Hwa, Lei Hou, Yaozu Xiang

“…We previously reported that inhibiting Na+/H+ exchanger 1 (NHE1) activity post-MI may improve outcomes, but not in the setting of MI with acute hyperglycemia. …”
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3‐HKA Promotes Vascular Remodeling After Stroke by Modulating the Activation of A1/A2 Reactive Astrocytes by Jun‐Min Chen, Guang Shi, Lu‐Lu Yu, Wei Shan, Jing‐Yu Sun, An‐Chen Guo, Jian‐Ping Wu, Tie‐Shan Tang, Xiang‐Jian Zhang, Qun Wang

“…In conclusion, 3‐HKA may promote post‐stroke vascular remodeling by regulating A1/A2 astrocyte activation, thereby improving long‐term neurological recovery, suggesting that supplementation with 3‐HKA may be an efficient therapy for stroke.…”
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Schizochytrium sp. as a promising Artemia tibetiana nauplii fortifier for yellow drum (Nibea albiflora) larviculture by Zihan Zhang, Pian Zhang, Kangjia Su, Peng Tan, Ligai Wang, Rijin Jiang, Xiaojun Yan, Yuming Zhang, Dongdong Xu

“…This enhancement was attributed to improved intestinal digestive functions, characterized by significant increases in muscular fold height, perimeter ratio, microvilli length, and microvilli density (P < 0.05). …”
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Acute effect of proprioceptive exercises on balance, joint position sense and muscle strength among elder and adult by Mansour Sahebozamani, Abdolhamid Daneshjoo, Saeid Bahiraei, Shima Sheikhbahaie, Sanaz Namazi Zadegan, Faeze Firouzi, Elahe Nasrolahzade, Maliheh Soltanabi

“…Assessments were conducted before, immediately after, and one hour post exercises. Data analysis was performed using a mixed model for repeated measures design. …”
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Exploring the associations between gut microbiota composition and SARS-CoV-2 inactivated vaccine response in mice with type 2 diabetes mellitus by Long Liu, Xianzhen He, Jiaqi Wang, Moran Li, Xiuli Wei, Jing Yang, Gong Cheng, Weixing Du, Zhixin Liu, Xiao Xiao

“…Compared with healthy mice, T2DM mice showed a higher Firmicutes/Bacteroidetes ratio 28 days post-vaccination. Significant alterations in gut microbiota composition were detected following vaccination, while lung microbiota remained unchanged. …”
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Impact of Acute Kidney Injury, Co-Existing with and without Chronic Kidney Disease on the Short&#x2010;Term Adverse Outcomes Following Atherosclerotic Cardiovascular Disease Events... by Chou CL, Zheng CM, Chiu HW, Tsou LLC, Kao PF, Hsu YH, Lin CL, Sung LC

“…Patients with DM who experienced the first ASCVD event were categorized by kidney function: no known kidney disease (NKD), AKI, CKD, and acute-on-CKD (AoCKD). …”
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Investigation of DC-Biased Optical OFDM With Precoding Matrix for Visible Light Communications: Theory, Simulations, and Experiments by Tao Jiang, Ming Tang, Rui Lin, Zhenhua Feng, Xi Chen, Lei Deng, Songnian Fu, Xiang Li, Wu Liu, Deming Liu

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Does model type influence the effectiveness of combined action observation and motor imagery training for novices learning an Ankle Pick takedown? by Samantha Chye, Ashika Chembila Valappil, Ryan Knight, Andrew Greene, David Shearer, Cornelia Frank, Ceri Diss, Adam Bruton, Adam Bruton

“…Both the AOMIOTHER and Control conditions led to improved functional changes in mental representation structures while the structures for the AOMISELF condition became less similar to the reference structure over time.DiscussionCollectively, the largely null findings (n = 13, 92.86%) suggest that physical practice has the strongest influence on motor adaptations for this complex motor skill at these early stages of learning. …”
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Effects of Weizmannia faecalis DSM 32016 on growth performance, gut microbiota, and health parameters in Holstein Friesian calves by Luca Marchetti, Raffaella Rebucci, Camilla Ceccarani, Lydia Zeibich, Caterina Piantoni, Paola Cremonesi, Bianca Castiglioni, Alexandra Schlagheck, Sabrina Bertani, Donata Cattaneo, Valentino Bontempo

“…Colostrum samples, collected from dams at 6 h and 12 h post-birth to assess immunoglobulins G content, showed IgG levels above 50 g/l. …”
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