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  1. 3341

    Unveiling Therapeutic Potential of Yoga Mitigating Oxidative Stress and Mitochondrial Dysfunction in PCOS: A Randomized Controlled Trial by Deepika Kumari, Manoj Kumar, Ashish Datt Upadhyay, Neena Malhotra, Reeta Mahey, Vatsala Dadhwal, Tushar Sehgal, Richa Mishra, Rima Dada

    Published 2025-01-01
    “…Result: The Yoga group showed a significant increase in mtDNA-CN and upregulation of transcripts responsible for maintaining mitochondrial integrity and the mitochondrial respiratory chain. In addition, the post-yoga group shows a reduction in, lipid peroxidation, inflammatory, OS markers, and an improvement in telomere length. …”
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  2. 3342

    Immediate management of a cirrhosis-induced severe pericardial effusion: a case report and review of the literature by Maryam Taheri, Arash Hassanpour Dargah, Pedram Ramezani, Mohsen Anafje, Amir Nasrollahizadeh, Pouya Ebrahimi, Mohammad Hossein Mandegar

    Published 2025-01-01
    “…Emergency pericardiocentesis was performed, aspirating 500 mL of serosanguinous fluid. Post-procedural management included continuous monitoring, repeat echocardiography, and a comprehensive pharmacological regimen addressing fluid overload, autoimmune hepatitis, and cardiac function. …”
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  3. 3343

    Effect of Individual Cognitive Stimulation Therapy on Dementia and Quality of Life in Older Adults: A Quasi-experimental Study by Pooja Motar Sublok, Mrunali Kerkar, Shivani Patil, Bhairavi Ugale

    Published 2025-02-01
    “…Introduction: Dementia is a chronic neurocognitive disorder that causes a decline in cognitive functions. As the global prevalence of dementia rises, non pharmacological therapies, such as Cognitive Stimulation (CS), have shown promise in preserving cognitive function and improving Quality of Life (QoL). …”
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  4. 3344

    Effectiveness of Educational Program on Nurse's Knowledge Concerning Management of Cardiogenic Shock at AL-Mosul Teaching Hospitals by Hakema S. Hassan, Ali M F. Hussein

    Published 2016-04-01
    “…Results: The results of the study showed that there is good improvement with highly significant differences in study group between pre and post tests in overall main domains. for the nurses' knowledge. …”
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  5. 3345

    Screening and transcriptomic analysis of anti-Sporothrix globosa targeting AbaA by Ying Wang, Xiaoyan Wu, Xiyuan Fan, Chanxu Han, Fangliang Zheng, Zhenying Zhang, Zhenying Zhang

    Published 2025-04-01
    “…Additionally, animal experiments demonstrated that Azelastine and Mefloquine reduced skin lesions in mice; post-treatment observations revealed improvements in inflammatory infiltration and granuloma formation. …”
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  6. 3346
  7. 3347

    Effect of Kegel Exercises on The Recurrence of Lower Urinary Tract Infection in Multiparty by Engy A. R. Khamis, Eman Abdelaziz, Ghada Hemdan

    Published 2024-02-01
    “…Multiple deliveries Reduced pelvic floor strength affects the bladder function because the bladder does not completely empty, leaving a 'pool' of urine, which can lead to recurrent urinary infection. …”
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  8. 3348

    Unravelling the neuroprotective effects of taxifolin against scopolamine-induced dementia in male Sprague Dawley rats: A comprehensive preclinical investigation by Heena Chauhan, Bhavya Nakum, Udit Chaube, Bhagawati Saxena

    Published 2025-03-01
    “…Taxifolin pre-treatment reversed these alterations, improving cognitive function, reducing oxidative stress and inflammation, and restoring antioxidant enzymes. …”
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  9. 3349

    Luteolin as an adjuvant effectively enhanced the efficacy of adoptive tumor-specific CTLs therapy by Zhiheng Lai, Yanyang Pang, Yujing Zhou, Leiyuan Chen, Kai Zheng, Shiguo Yuan, Wu Wang

    Published 2025-03-01
    “…Recent studies suggest that its anti-tumor effects are linked to enhanced CTL function—including proliferation, survival, and cytotoxicity-via inhibition of the YAP/Wnt signaling pathway in tumor cells. …”
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  10. 3350

    Effects of Surgery on Hemodynamics and Postoperative Delirium in Stanford Type A Aortic Dissection by Fan Y, Liu X, Li Z, Xiang D

    Published 2024-11-01
    “…Group sizes differ due to retrospective categorization based on observed outcomes rather than controlled sampling.Results: ① Hemodynamic parameters: Postoperative MAAD and LVEDd were significantly reduced, while LVEF increased compared to preoperative levels (P < 0.05). ② Surgical and postoperative conditions: Group A had longer surgery, cardiopulmonary bypass, and deep hypothermic circulatory arrest times than Group B (P < 0.05). ③ Univariate analysis of baseline data: Group A had higher rates of patients aged ≥ 60, hypertension, history of stroke, and elevated preoperative D-dimer levels (P < 0.05). ④ Multivariate logistic analysis: Independent risk factors for postoperative delirium included age ≥ 60, hypertension, history of stroke, surgery time > 6 hours, cardiopulmonary bypass time > 3 hours, and deep hypothermic circulatory arrest time > 40 minutes (OR > 1, P < 0.05).Conclusion: Surgical treatment of Stanford Type A aortic dissection has a good effect, significantly improving long-term cardiac function. However, the incidence of postoperative delirium is relatively high and is closely related to factors such as age, hypertension, history of stroke, surgery time, cardiopulmonary bypass time, and deep hypothermic circulatory arrest time.Keywords: Stanford Type A aortic dissection, surgical intervention, hemodynamic parameters, postoperative delirium, impact, investigation…”
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  11. 3351

    Approach to mechanical ventilation: a simplified approach for a pulmonologist by Pratap Upadhya, Sanjana H S, Harshith R, Vemuri Mahesh Babu, Karthik Balasoupramaniane, Zeenathaalam Nadaf

    Published 2025-06-01
    “…Successful weaning depends on maintaining stable respiratory function, with close monitoring to prevent post-extubation failure. …”
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  12. 3352

    Study protocol: a randomised controlled proof-of-concept real-world study – does maximising time in range using hybrid closed loop insulin delivery and a low carbohydrate diet rest... by Shareen Forbes, Faye Baxter, Nicola Baillie

    Published 2022-12-01
    “…Hybrid closed loop (HCL) technologies improve glycaemic time in range (TIR). However, post-prandial glycaemic excursions are still evident. …”
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  13. 3353

    Feasibility and accuracy of CARLO© guided optic canal unroofing by Schicker Martina, Tu Ha Thanh, Luder Yann, Morawska Marta, Röthlisberger Michel

    Published 2024-09-01
    “…This critical intervention focuses on relieving pressure and decompressing the optic nerve to safeguard vision, restore optimal nerve function, and enhance the surgical view during aneurysm therapy. …”
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  14. 3354

    513 A CTS team approach to investigate skeletal muscle diseases and countermeasures in a donor-derived bioengineered muscle platform by Karly Caples, Vinicius Mariani, Elisabeth Barton, Siobhan Malany

    Published 2025-04-01
    “…Objectives/Goals: Our team has developed a 24-well donor-derived skeletal muscle microphysiological system (MPS) to study signaling pathways associated with a variety of muscle diseases. 3D muscle will be utilized to evaluate pharmacologic interventions for these muscle conditions to improve both muscle mass and function. Methods/Study Population: In this study, muscle MPS were formed from healthy young female and male subjects. 3D muscle underwent a 21-day differentiation with an electrical stimulation (e-stim) regimen twice daily beginning on Day 14. …”
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  15. 3355

    Osteoperiosteal versus osteochondral for autologous transplantation in the treatment of large cystic osteochondral lesions of the talus by Lequan Liu, Jiangtao Jin, Jinping Pan, Huikang Guo, Sen Li, Jisheng Li, Zheng Zhang

    Published 2025-02-01
    “…Results The within-group comparison showed significant improvements in pain severity and function in both groups post-treatment compared with pre-treatment. …”
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  16. 3356

    Interventional Radiology Management of Renal Artery Stenosis After Kidney Transplant: Single-Center Experience and Management Strategies by Ahmad Mirza, Munazza Khan, Usman Baig, Shameem Beigh, Imran Gani

    Published 2025-06-01
    “…<b>Conclusions:</b> Percutaneous interventional treatment for renal artery stenosis is associated with improvements in hemodynamic parameters and the stabilization of allograft function. …”
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  17. 3357

    Smart Thrombosis Care: The Rise of Closed-Loop Diagnosis-to-Treatment Nano Systems by Wu J, Zhang Y, Chen W, Hao T, Ran C, Zhou Y, Shen Y, You W, Wang T

    Published 2025-06-01
    “…Techniques such as platelet aggregation assays, coagulation function tests, biomarker detection, and nanotechnology-based therapies are discussed. …”
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  18. 3358

    Evidence that multiple defects in lipid regulation occur before hyperglycemia during the prodrome of type-2 diabetes. by Simon G Anderson, Warwick B Dunn, Moulinath Banerjee, Marie Brown, David I Broadhurst, Royston Goodacre, Garth J S Cooper, Douglas B Kell, J Kennedy Cruickshank

    Published 2014-01-01
    “…<h4>Interpretation</h4>Defects in adipocyte function from excess energy storage as relatively hypoxic visceral and hepatic fat, and impaired mitochondrial fatty acid oxidation may initiate the observed perturbations in lipid metabolism. …”
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  19. 3359

    Weight-Bearing Versus Non-Weight-Bearing After Ankle Fracture: A Systematic Review and Meta-Analysis of Patient-Reported Outcome by Rafael Llombart-Blanco, Gonzalo Mariscal, Ibrahim Khalil, Violeta Cordón, María Benlloch, Carlos Barrios, Rafael Llombart-Ais

    Published 2025-02-01
    “…Results: Eleven studies (<i>n</i> = 939) showed favorable outcomes with weight-bearing. Significant functional improvements were observed at 6 weeks (MD 7.88, 95% CI 3.14–12.61), 3 months (MD 5.79, 95% CI 4.41–7.17), and 12 months (MD 4.74, 95% CI 3.01–6.46). …”
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  20. 3360

    Effect of minimally invasive posterior veneer Preparation designs on failure load and mode after fatigue (in-vitro study) by Islam Mohamed Mady, Ahmed Safwat El Kady, Moustafa Nabil Aboushelib, Mohamed Hussein A. Hussein

    Published 2025-07-01
    “…Abstract Background Ceramic veneers are a common option for enhancing dental aesthetics by improving tooth form, shade, and function. Preparation design is considered a critical factor in the success of dental veneers, as it influences the failure load and fatigue survival of posterior minimally invasive ceramic veneer restorations. …”
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