Complementary interventions for cognitive rehabilitation in patients with cerebral palsy: a single-center study by Ammara Rafique

“…These cognitive functions are likely attributable to increased neuronal activity in the prefrontal cortex and elevated serotonin levels. …”
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Generation and evaluation of a novel PI3K-targeting gene therapy in the failing mouse heart and healthy sheep heart by Sebastian Bass-Stringer, Daniel G. Donner, Clive N. May, Aya Matsumoto, Emma I. Masterman, Aascha A. D'Elia, Yi Ching Chen, Helen Kiriazis, Jieting Luo, Roger Chooi, Clara Liu Chung Ming, Paul Gregorevic, Colleen J. Thomas, Bianca C. Bernardo, Kate L. Weeks, Julie R. McMullen

“…I/R mouse hearts treated with the AAV6-cTnT-IVS2-iSH2 displayed increased phosphorylation of Akt, but no improvement in cardiac function or structure was observed. …”
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Public and patient involvement (PPI) in the design, execution and dissemination of a trial: the BISTRO trial by David Coyle, Paula Ormandy, Nancy Fernandes da Silva, Simon Davies

“…Background For people receiving haemodialysis, a balance has to be struck between removing sufficient but not too much fluid during a treatment session and maintaining any remaining kidney function they might have. In the BISTRO trial, this study sought to establish if getting the balance right might be improved by the additional use of bioimpedance, a device that measures body fluid composition to help decide how much fluid to remove during dialysis. …”
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Reperfusion injury case following cervical fusion with OPLL: a case report and literature review by Assil Mahamid, Sana Zahalka, David Maman, Liad Alfandari, Amit Keren, Eyal Behrbalk

“…After a few days, we observed a significant improvement in motor function in the right leg; however, there was no change in the right hand. …”
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Effects of bronchoscopic alveolar lavage–assisted mechanical ventilation on postoperative pulmonary infection and inflammatory factors in patients undergoing lung cancer surgery by Hui Zhu, Haiyang Lu

“…Conclusions: BAL-assisted MV can achieve better results in treating postoperative PI than MV alone, effectively improving respiratory function and reducing systemic inflammatory response.…”
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Chronic hepatitis B and risk of kidney involvement by M. V. Mayevskaya, I. N. Tikhonov, V. T. Ivashkin

“…Telbivudine is a drug of choice among new anti-HBV agents for treatment of patients, having high risk of renal disease, which demonstrates not only absence of nephrotoxicity, but also the proved predictable improvement of renal function.…”
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Comparing the effects of positional versus myofascial release of gluteus medius to manage patellofemoral pain syndrome: single blinded randomized clinical trial by Priyanka Ratan Kumar, Rabail Rani Soomro

“…Both the groups showed a significant reduction in pain, improvement in function, pressure pain threshold, strength, and quality of life (p<0.05). …”
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Effect of vestibular rehabilitation treatment (VRT) on patients with unsteadiness after intratympanic gentamicin in Menière’s disease: protocol for a randomised controlled trial by Peixia Wu, Yue Zhou, Qiling Tong, Huiqian Yu

“…The outcomes assessments will be conducted at baseline and at eighth week and sixth month post-randomisation. The primary outcome will be the improvements in vestibular function quantified through the Functional Gait Assessment. …”
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Translational research from bioinformatics to animal studies: Exploring gene expression and muscle health in COPD through selenium nanoparticles and exercise by Mahdi Bakhshi, Abdolali Bnaeifar, Sajjad Arshadi, Behzad Bazgir

“…This study underscores the importance of PGC-1α in regulating mitochondrial function and oxidative stress in COPD. The findings suggest that PGC-1α could serve as a potential therapeutic target, offering insights into the development of interventions aimed at improving respiratory health in COPD patients. …”
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Single-cell RNA sequencing reveals adrb1 as a sympathetic nerve-regulated immune checkpoint driving T cell exhaustion and impacting immunotherapy in esophageal squamous cell carcin... by Qun Li, Shuning Xu, Yulin Ren, Cheng Zhang, Ke Li, Ying Liu

“…Blocking this pathway could restore T cell function. Recent advances in single-cell RNA sequencing (scRNA-seq) have enabled deeper insights into tumor heterogeneity and the immune landscape, opening the door for personalized treatment strategies that may improve survival and reduce resistance to therapy.MethodsWe combined scRNA-seq with bulk RNA analysis to explore adrenergic receptor signaling in ESCC, focusing on changes before and after neoadjuvant therapy. …”
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System‐wide optimization of an orthogonal translation system with enhanced biological tolerance by Kyle Mohler, Jack M Moen, Svetlana Rogulina, Jesse Rinehart

“…However, despite significant advances in OTS design and function, the systems‐level biology of OTS development and utilization remains underexplored. …”
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Psychotic Symptoms in Cataract Patients Without Overt Psychosis Are Ameliorated Following Successful Cataract Surgery by Georgios D. Floros, Ioanna Mylona, Stylianos Kandarakis

“…Higher improvement in those variables was associated with higher improvement in visual acuity while controlling for age, gender and stressful life events during the past six months. …”
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Therapeutic effects of a horse riding simulator in children with cerebral palsy by Maria Beatriz Silva Borges, Maria José da Silva Werneck, Maria de Lourdes da Silva, Lenora Gandolfi, Riccardo Pratesi

“…CONCLUSION: The horse ridding simulator produced significant improvement in the postural control of children in sitting position, additionally showing a higher motor functionality and a better acceptance of the therapeutic intervention.…”
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The impact of preoperative anxiety and depression on the prognosis of patients with painful accessory navicular by Jia-chen Liang, Qiang Zan, Shi-Hang Cao, Xiao-cong Liu, Jing Huang, Yi Li, Jun-kui Xu

“…Furthermore, it investigated the differences between patients’ pre- and post-operatively, analyzing the impact on post-operative pain and functional recovery. …”
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Multicentre pilot randomised clinical trial of early in-bed cycle ergometry with ventilated patients by Michelle E Kho, Alexander J Molloy, France J Clarke, Julie C Reid, Margaret S Herridge, Timothy Karachi, Bram Rochwerg, Alison E Fox-Robichaud, Andrew JE Seely, Sunita Mathur, Vincent Lo, Karen EA Burns, Ian M Ball, Joseph R Pellizzari, Jean-Eric Tarride, Jill C Rudkowski, Karen Koo, Diane Heels-Ansdell, Deborah J Cook

“…Introduction Acute rehabilitation in critically ill patients can improve post-intensive care unit (post-ICU) physical function. …”
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Dietary Probiotic <i>Bacillus subtilis</i> AAHM-BS2360 and Its Postbiotic Metabolites Enhance Growth, Immunity, and Resistance to Edwardsiellosis in <i>Pangasianodon hypophthalmus<... by Nugroho Wiratama, Pakapon Meachasompop, Benchawan Kumwan, Yosapon Adisornprasert, Prapansak Srisapoome, Phornphan Phrompanya, Patcharapong Thangsunan, Pattanapong Thangsunan, Kanokporn Saenphet, Supap Saenphet, Wararut Buncharoen, Anurak Uchuwittayakul

“…Dietary supplementation with <i data-eusoft-scrollable-element="1">B. subtilis</i> AAHM-BS2360, its metabolites, and their combination enhanced immune response, reduced oxidative stress, and improved growth performance in pangasius, highlighting its potential as a functional feed additive for sustainable aquaculture.…”
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Possibilities of hyperuricemia correction in acute decompensation of heart failure by Laura H. Sarieva, Svetlana N. Nasonova, Marina D. Muksinova, Igor V. Zhirov, Sergey N. Tereshchenko

“…The use of allopurinol reduces uric acid concentration, which is accompanied by improvement of renal function as HF signs are compensated, and also has a favourable safety profile when used in patients with ADHF, hyperuricemia and Chronic Kidney Disease.…”
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Sex differential impact of comorbidities in spondyloarthritis: data from COMOSPA study by Maxime Dougados, Anna Molto, Jordi Gratacós, Clementina López-Medina, Mireia Moreno, Maria Llop, Marta Arevalo Salaet, Joan Calvet, Antoni Berenguer-Llergo

“…In contrast, osteoporosis had a more pronounced effect on physical function in male patients.Conclusions Comorbidities exert distinct influences on disease activity, physical function and health-related quality of life in male and female patients with SpA. …”
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A novel second-stage surgical strategy for severely obese patient with pancreatic neuroendocrine tumor: a case report by Akira Umemura, Akira Sasaki, Hiroyuki Nitta, Hirokatsu Katagiri, Shoji Kanno, Daiki Takeda, Taro Ando, Satoshi Amano, Masao Nishiya, Noriyuki Uesugi, Tamotsu Sugai

“…LSG before pancreatectomy may have a potential to reduce pancreas thickness and recovery of islet β cell function in severely obese patients, thereby reducing the risk of clinically relevant POPF and post-pancreatectomy T2D onset.…”
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Electrophysiological Evidence on Mirror Therapy for Promoting Perceptuo-Motor Processes in Stroke Patients by Li Ding, Dan Wang, Chengcheng Wu, Xu Wang, Jinyang Zhuang, Xiaoli Guo, Jie Jia

“…Behavioral analysis showed that enhanced accuracy of the HMR task, correlating with greater improvement in upper extremity motor function, was only observed in the MG. …”
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