Ponatinib and other clinically approved inhibitors of Src and Rho-A kinases abrogate dengue virus serotype 2- induced endothelial permeability by Srishti Rajkumar Mishra, Ayan Modak, Mansi Awasthi, Archana Sobha, Easwaran Sreekumar

“…In in-vivo studies using DENV2-infected AG129 IFN receptor-α/β/γ deficient mice, ponatinib, when administered 24 h post-infection onwards, demonstrated significant benefits in improving body weight, clinical outcomes, and survival rates. …”
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Alpha absolute power: motor learning of practical pistol shooting Potência absoluta de alfa: aprendizagem motora do tiro prático de pistola by Clayton Amaral Domingues, Sergio Machado, Emerson Garcia Cavaleiro, Vernon Furtado, Mauricio Cagy, Pedro Ribeiro, Roberto Piedade

“…A One-way ANOVA with repeated measures and a post hoc analysis were employed to observe modifications on behavioral and electrophysiological measures (p<0.05). …”
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Intravenous patient-controlled analgesia versus epidural anesthesia in the treatment of patients undergoing total hip arthroplasty: a retrospective comparative study by Qian Wu, Xiao Jun Zhi

“…Abstract Background Total hip arthroplasty is a common surgical procedure used to reduce pain and improve hip joint function in patients with advanced hip inflammation. …”
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The effectiveness of ERCP in managing preoperative complications of choledochal cysts in children and its role in facilitating early surgical intervention by Tian Zhang, Wenjie Wu, Yijun Shu, Hao Weng, Mingzhe Weng, Ying Zhou, Xuefeng Wang

“…Sixty-five patients successfully completed their treatments, with 64 experiencing alleviation of symptoms. Significant improvements were observed in serum amylase levels and liver function tests following ERCP. …”
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Safety and efficacy of outpatient intravenous diuresis in decompensated heart failure: a systematic review by Roshni S. Kalkur, John P. Hintz, Girish Pathangey, Katharine A. Manning

“…Demographics, visit data, and outcomes were collected, and 30-day outcomes were compared to inpatient IV (IP IV) diuresis from 2021 Medicare HF hospitalizations.ResultsThe review included 1,590 unique patients treated with OP IV diuretics, with a mean age of 70 ± 6 years, 69.7% male, and 74.8% NYHA III-IV. Minimal adverse post-diuresis events such as hypokalemia, hypotension, and worsening renal function occurred (4.5%, 0.7%, and 2.3% respectively). …”
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Feasibility and usability of remote transcranial direct current stimulation (tDCS) for self-regulation in children with autism: protocol for a randomized controlled pilot study by Norna Abbo, Trina Mitchell, Seyed Hassan Tonekaboni, Evdokia Anagnostou, Brendan F. Andrade, Kevin Thorpe, Deryk S. Beal

“…Impaired response inhibition and self-regulation in ASD have been shown to be related to abnormal functional network connectivity in the dorsolateral prefrontal cortices (DLPFC). …”
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Effectiveness of Walking Prescription Using Mobile Health Technology on the Changes in Daily Steps in Older Adults With Cognitive Impairment: Randomized Controlled Study by Hee Jung Kim, Yun Jung Hwang, Jee Eun Park, Dong Young Lee

“…Changes in daily steps (primary outcome), cognitive function, physical status, and depressive symptoms from baseline to post-intervention (12 weeks) and follow-up (24 weeks) were assessed by unblinded researchers. …”
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Navigating the Risk Landscape in ST-Elevation Myocardial Infarction Patients Postpercutaneous Coronary Intervention: A Narrative Review by Utkarsh Gaur, Charuta Gadkari, Aditya Pundkar

“…The paper underscores the need for continuous innovation and research at both pre-hospital and post-PCI management levels to reduce mortality rates and improve the long-term outcomes of high-risk STEMI patients.…”
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Adipose tissue deficiency impairs transient lipid accumulation and delays liver regeneration following partial hepatectomy in male Seipin knockout mice by Qianqian Dong, Ziwei Liu, Yidan Ma, Xin Chen, Xiaowei Wang, Jinye Tang, Kexin Ma, Chenxi Liang, Mengyu Wang, Xiaoqin Wu, Yang Liu, Yaru Zhou, Hongyuan Yang, Mingming Gao

“…Liver and plasma samples were collected at various time points post‐surgery. Histological assessments, lipid accumulation analyses and measurements of hepatocyte proliferation markers were conducted. …”
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Symptomatic and cognitive effects of D-amino acid oxidase inhibitors in patients with schizophrenia: a meta-analysis of double-blind randomized controlled trials by Chun-Hung Chang, Yu-Der Hsia, Wen-Chun Liu, Jia-Hau Lee, Chieh-Hsin Lin, Hsien-Yuan Lane

“…Clinical and cognitive improvements were compared between baseline and post-DAOI treatment using standardized mean differences (SMDs) with 95% confidence intervals (CIs). …”
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Physical activity interventions in adult kidney transplant recipients: an updated systematic review and meta-analysis of randomized controlled trials by Roseanne E. Billany, Nicolette C. Bishop, Ellen M. Castle, Matthew P. M. Graham-Brown, Sharlene A. Greenwood, Courtney J. Lightfoot, Thomas J. Wilkinson

“…Most studies used a mixture of aerobic and resistance training but reporting and intervention content was highly varied. Significant improvements were observed in CRF (V̇O2peak; +3.87 mL/kg/min, p = .0004), physical function (sit-to-stand-60; +7.72 repetitions, p = .0001), and high-density lipoprotein (HDL; +0.13 mmol/L, p = .02). …”
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Implementing My PreHab Program: How digital technology helped to bridge the hospital-community gap and streamline hospital processes by Eleanor R Bills, Anastasia D Westin, Jane M Andrews

“…These complications are associated with worse psychosocial outcomes, delayed function recovery, financial costs and reduced patient flow. …”
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Low molecular weight hyaluronates: biological action, efficacy, safety and clinical experience in the treatment of musculoskeletal pain syndromes (literature review and clinical ob... by M. A. Strakhov, L. I. Alekseeva, K. K. Maremkulov

“…The authors present their own clinical experience in the treatment of patients with musculoskeletal (MS) pain syndromes.It has been shown that i/a administration of HA can effectively reduce the intensity of pain and improve joint function, and when injected into the synovial sheaths of tendons, it can also relieve pain of extra-articular localization. …”
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Spinal cord injury repair based on drug and cell delivery: From remodeling microenvironment to relay connection formation by Wanrong Ma, Xing Li

“…Recently, tissue engineering (TE) has emerged as a promising approach for promoting neural regeneration and functional recovery in SCI, which can effectively delivery drugs into injury site and delivery cells and improve the survival and differential. …”
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Mission Planning for LEO Satellite IoT Constellation Based on Genetic Algorithm by Yanhong LI, Qiang LYU, Junmin LIANG, Shigang FENG, Junhou MIAO

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Automated assembly of molecular mechanisms at scale from text mining and curated databases by John A Bachman, Benjamin M Gyori, Peter K Sorger

“…Abstract The analysis of omic data depends on machine‐readable information about protein interactions, modifications, and activities as found in protein interaction networks, databases of post‐translational modifications, and curated models of gene and protein function. …”
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Rehabilitation of the Upper Extremity after Stroke: A Case Series Evaluating REO Therapy and an Auditory Sensor Feedback for Trunk Control by G. Thielman, P. Bonsall

“…With both interventions, clinically relevant improvements were found for measures of body function and structure, as well as for activity, for two participants. …”
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Pro: Clinical remission in asthma – implications for asthma management by Stefania Principe, Nizar N. Jarjour

“…Real-world studies and post hoc analyses of clinical trials emphasise the potential of biologics in achieving clinical remission in a significant proportion of patients. …”
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Breaking the Mold: Bilateral Lateral End Clavicle Fractures Treated with Dog Bone Button Fixation - A Rare Case by Nitesh Kumar Rathi, D Raja Sujith Kumar, J Benjamin Vinodh, Naveen Sathyaseelan, Arun Vignesh

“…Surgical fixation using the dog bone button technique was performed bilaterally. Post-operative rehabilitation involved early mobilization, and at 6 weeks, the patient demonstrated significant functional improvement, confirmed by disabilities of the arm, shoulder and hand and Oxford shoulder scores. …”
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The Relationship Between Obesity, Bariatric Surgery, and Infertility: A Systematic Review by Charalampos Voros, Antonia Varthaliti, Kyriakos Bananis, Despoina Mavrogianni, Diamantis Athanasiou, Antonia Athanasiou, Aikaterini Athanasiou, Anthi-Maria Papahliou, Constantinos G. Zografos, Panagiota Kondili, Menelaos Darlas, Ioannis Papapanagiotou, Maria Anastasia Daskalaki, Marianna Theodora, Panagiotis Antsaklis, Georgios Daskalakis, Dimitrios Loutradis

“…More than 75% of the studies analyzed showed improvements in ovulatory function, monthly regularity, or spontaneous pregnancy after bariatric surgery. …”
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