Reversible ubiquitination conferred by domain shuffling controls paired NLR immune receptor complex homeostasis in plant immunity by Zhiyi Chen, Jianhua Huang, Jianyu Li, Frank L. H. Menke, Jonathan D. G. Jones, Hailong Guo

“…Phylogenetic analysis suggests this regulation likely transferred from WRKY70/WRKY41 to RRS1 upon WRKY domain integration. Our findings improve our understanding of homeostatic regulation of paired NLR complex and uncover a paradigm whereby domain integration can co-opt preexisting post-translational modification to regulate novel protein functions.…”
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The use of brain-machine interface, motor imagery, and action observation in the rehabilitation of individuals with Parkinson's disease: A protocol study for a randomized clinical... by Kátine Marchezan Estivalet, Tatiana Salayaran de Aguiar Pettenuzzo, Natália Lopes Mazzilli, Luis Fernando Ferreira, Fernanda Cechetti

“…Each participant will be assessed at three points: pre-intervention, post-intervention, and at a follow-up four weeks after the intervention ends. …”
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Preventing muscle loss through early mobilization in non-critically ill older adults admitted to surgical intensive care units by Onuma Chaiwat, Thanadol Wachiramatee, Benjaporn Sathitkarnmanee, Suchera Rattanamung, Piyapat Dajpratham, Napat Thikom, Chayanan Thanakiattiwibun

“…Early mobilization did not significantly alter muscle strength or mass but safely increased mobilization intensity, reduced infections, and improved short-term functional outcomes in older SICU patients. …”
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Pain Reduction After Laser Acupuncture Treatment in Geriatric Patients with Knee Osteoarthritis: a Randomized Controlled Trial by Dwi R Helianthi, Christina Simadibrata, Adiningsih Srilestari, Edy R Wahyudi, Rudy Hidayat

“…Aim: to compare the effectiveness of active laser acupuncture with placebo on reducing pain intensity and improving functional outcome in geriatric patients with knee osteoarthritis (OA). …”
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Pain Reduction After Laser Acupuncture Treatment in Geriatric Patients with Knee Osteoarthritis: a Randomized Controlled Trial by Dwi R Helianthi, Christina Simadibrata, Adiningsih Srilestari, Edy R Wahyudi, Rudy Hidayat

“…Aim: to compare the effectiveness of active laser acupuncture with placebo on reducing pain intensity and improving functional outcome in geriatric patients with knee osteoarthritis (OA). …”
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Efficacy of vericiguat in patients with chronic heart failure and reduced ejection fraction: a prospective observational study by Yinge Zhan, Liu Li, Jie Zhou, Yishan Ma, Xuchong Guan, Suo Wang, Ya Chang

“…Data were collected at baseline and at 1, 3, and 6 months post-discharge, including NT-proBNP, sST2, and echocardiographic assessments. …”
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Systematic review and meta-analysis: do best-evidenced trauma-focused interventions for children and young people with PTSD lead to changes in social and interpersonal domains? by Alice R. Phillips, Sarah L. Halligan, Megan Bailey, Marianne Skogbrott Birkeland, Iris Lavi, Richard Meiser-Stedman, Hannah Oram, Susan Robinson, Tamsin H. Sharp, Rachel M. Hiller

“…Objective: Young people with post-traumatic stress disorder experience difficulties in social and interpersonal domains. …”
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The impact of dental intervention under general anesthesia in Kohlschutter-Tonz Syndrome: a case series by Mervat Khoury Absawi, Ali Shama, Kholoud Fahoum, Iris Slutzky-Goldberg, Fares Kablan, Idan Redenski, Samer Srouji

“…Reports indicated a clear improvement both in patients and family domains of ECOHIS post-operatively. …”
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Combined effect of prefrontal transcranial direct current stimulation and a working memory task on heart rate variability. by Stevan Nikolin, Tjeerd W Boonstra, Colleen K Loo, Donel Martin

“…Response time on the WM task, but not accuracy, improved from baseline to during-tDCS and post-tDCS with sham, but not active, stimulation. …”
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Catalase Activity in the Brain Is Associated with Recovery from Brain Injury in a Piglet Model of Traumatic Brain Injury by Stephanie T. Dubrof, Sarah L. Schantz, Taylor H. LePage, Sydney E. Sneed, Savannah R. Cheek, Holly A. Kinder, Kylee J. Duberstein, David A. DeWahl, Jerry O. Stern, Alexander B. Baguisi, Erin E. Kaiser, Franklin D. West, Hea Jin Park

“…Importantly, within CMX-2043 treated TBI groups, piglets with significantly decreased lesion volumes, midline shift, and combined swelling and atrophy had better brain recovery, determined by MRI on day 1, 7, and 42 days post-injury TBI, exhibited higher brain catalase activity at 42 days post-injury TBI regardless of administration route, suggesting a link between improved recovery and sustained local catalase activity. …”
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Automatic detection of optic canal fractures and recognition and segmentation of anatomical structures in the orbital apex based on artificial intelligence by Yu-Lin Li, Yu-Hao Li, Mu-Yang Wei, Guang-Yu Li

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Selective Vein Graft Cold Cardioplegia and Warm Reperfusion to Enhance Early Recovery in Patients with Left Ventricle Depression Undergoing Coronary Artery Surgery by Pasquale Totaro, Martina Musto, Eduardo Tulumello, Antonella Degani, Vincenzo Argano, Stefano Pelenghi

“…In patients with depressed left ventricular function, however, especially if associated with severe multiple coronary stenosis, increased pharmacological and/or mechanical support in the early post-CPB period is often required to support left ventricular recovery. …”
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The impact of pituitary adenomas on cognitive performance: a systematic review by Ting-Chia Young, Kai-Yen Lin, Wan-Cheng Li, Chi-Ning Huang, Wen-Hsuan Tsai

“…Perioperative changes in cognitive performance were described in 14 studies, of which 11 reported post-surgical improvement in at least one cognitive domain. …”
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A Pilot Study Evaluating the Effectiveness of Platelet-Rich Plasma Therapy for Treating Degenerative Tendinopathies: A Randomized Control Trial with Synchronous Observational Cohor... by Marni Wesner, Terry Defreitas, Heather Bredy, Louisa Pothier, Ziling Qin, Ashley B McKillop, Douglas P Gross

“…Preliminary results indicate intratendinous, ultrasound-guided PRP injection may lead to improvements in pain, function, and MRI-documented tendon pathology.…”
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Successful Treatment of Transplanted Kidney Patient with 100% Lung Damage Caused by COVID-19 Bilateral Pneumonia: a Clinical Case by R. R. Nuriakhmetov, V. S. Panteleev, A. R. Zagitov, M. A. Nartailakov, M. N. Kornilov, I. I. Biganyakov

“…Within 5 months since discharge, there were observed a general well-being improvement, 98% oxygen saturation, absent oedema, satisfactory transplanted kidney function.Conclusion. …”
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The impact of local symptoms on health‐related quality of life in vulvar cancer survivors—A nationwide prospective study by Diana Zach, Pernille T. Jensen, Henrik Falconer, Zuzana Kolkova, Katja Stenström Bohlin, Preben Kjølhede, Ivette Raices Cruz, Elisabeth Åvall‐Lundqvist, Angelique Flöter Rådestad

“…Emotional‐, role‐, social‐, and cognitive functioning, global and mental health improved significantly after treatment. …”
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Practical Anemia Bundle for Sustained Blood Recovery (PABST-BR) in critical illness: a protocol for a randomised controlled trial by Laurie Meade, Andrea Cheville, Matthew A Warner, Phillip J Schulte, Daryl J Kor, Ognjen Gajic, Ronald S Go, William B Beam, Jonathan E Charnin, Kim A Droege, Brenda K Anderson, Matthew L Johnson, Brad Karon

“…However, the impact of interventions designed to attenuate or treat anaemia during critical illness on post-hospitalisation haemoglobin recovery and functional outcomes is unclear.Methods and analysis The Practical Anemia Bundle for Sustained Blood Recovery (PABST-BR) clinical trial is a pragmatic, open-label, parallel group, single-centre, randomised clinical trial assessing the impact of a multifaceted anaemia prevention and treatment strategy versus standard care for improvement of haemoglobin concentrations and functional outcomes after critical illness. …”
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First results of long-term follow-up of children in Russia after gene therapy for hereditary retinal dystrophies associated with biallelic mutations in the RPE65 gene by V. V. Neroev, L. A. Katargina, M. P. Kharlampidi, L. V. Kogoleva, I. V. Zolnikova, P. A. Ilyukhin, E. V. Denisova, S. V. Milash, N. A. Osipova, S. I. Kutsev, A. V. Polyakov, R. A. Zinchenko, V. V. Kadyshev, Yu. A. Bobrovskaya

“…The results of a one-year post VN treatment follow-up of Russian patients with RPE65-associated inherited retinal disease demonstrate stabilization and improvement of visual functions, which is especially important for otherwise incurable patients with a progressive course of the disease.…”
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Design and Implementation of Attention-Based CR System in the Context of Big Data by Zheyi Wang, Yanli Kuang, Xin Lyu

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Evaluating the short-term effects of dance on motor and non-motor outcomes in people living with Parkinson's: A crossover study. by Anna M Carapellotti, Matthew Rodger, Michail Doumas

“…<h4>Results</h4>Results showed functional mobility (measured by the Timed Up and Go) improved to a greater extent after dance compared to the lecture. …”
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