Development and evaluation of customized software to automatically align macula and optic disc centered scanning laser ophthalmoscope fundus images by M. Elena Martinez-Perez, Franziska G. Rauscher, Pingping Zhao, Tobias Elze

“…Obtaining it post-measurement requires manual registration of the macula and optic disc optical coherence tomography (OCT) imaging data. …”
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Variation-resilient spike-timing-dependent plasticity in memristors using bursting neuron circuit by Yize Liu, Jiayi Zhao, Yu Xiao, Peng Chen, Haisong Chen, Enhui He, Peng Lin, Gang Pan

“…Spike-timing-dependent plasticity (STDP) is a classic synaptic function that facilitates learning and memory in a biological brain. …”
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Cardiac resynchronization therapy via left bundle branch pacing in heart failure with complete left bundle branch block: is the defibrillator needed? by Dandan Yang, Dandan Yang, Qunchao Ma, Qunchao Ma, Hong Zhu, Lihua Wang, Meixiang Xiang, Meixiang Xiang, Jian’an Wang, Jian’an Wang, Jian’an Wang, Jian’an Wang, Xiaohong Pan, Xiaohong Pan

“…All patients exhibited a super-response to LBBP cardiac resynchronization therapy, achieving complete improvement in cardiac function with a LVEF exceeding 50%. …”
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Salvianolic Acid B Alleviates LPS-Induced Spleen Injury by Remodeling Redox Status and Suppressing NLRP3 Inflammasome by Hao Wang, Xiao Dou, Ruixue Wang, Yuxin Jiang, Jinsong Zhang, Xianjuan Qiao, Yingjun Liu, Hao Zhang, Chenhuan Lai, Yanan Chen, Qiang Yong

“…Blood and spleen tissues were harvested 6 h post-injection for biochemical analysis. <b>Results</b>: LPS induced systemic immune disorders in piglets, as evidenced by increased immune organ indices and decreased white blood cell, lymphocyte, and basophil counts in blood (<i>p</i> < 0.05). …”
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Ultrasound-Guided Versus Landmark-Based Extracorporeal Shock Wave Therapy for Calcific Shoulder Tendinopathy: An Interventional Clinical Trial by Iosif Ilia, Caius Calin Miuta, Gyongyi Osser, Brigitte Osser, Csongor Toth, Manuela Simona Pop, Ramona Nicoleta Suciu, Veronica Huplea, Victor Niculescu, Laura Ioana Bondar

“…<b>Conclusions</b>: Ultrasound-guided ESWT was significantly more effective than landmark-based ESWT in improving shoulder function, reducing pain, and promoting calcific deposit resorption. …”
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TBK1 is involved in programmed cell death and ALS-related pathways in novel zebrafish models by Quentin Raas, Gregoire Haouy, Hortense de Calbiac, Elena Pasho, Anca Marian, Ida Chiara Guerrera, Marion Rosello, Patrick Oeckl, Filippo Del Bene, Alberto Catanese, Sorana Ciura, Edor Kabashi

“…This gene is linked to autophagy and inflammation, two cellular mechanisms reported to be dysregulated in ALS patients, although its functional role in the pathogenesis could involve other players. …”
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The impact of six weeks of swimming exercise on the levels of proteins associated with the myelination of hippocampal tissue in Wistar rats with multiple sclerosis by Mohammad Rami, Samaneh Rahdar, Sayed Shafa Marashi, Abdolhamid Habibi

“…The data were analyzed using one-way ANOVA and post-hoc comparisons were made by using Tukey's test at a significance level of p<0.05.Results: The findings of the shuttle box and rotarod tests revealed that the MS group had impaired memory function and balance maintenance, but these improved significantly after swimming training (p<0.001). …”
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Influence of crouch angle on lower-extremity kinetic gait profile and walk distance in children with cerebral palsy: a cross-sectional study by Rajani Mullerpatan, Triveni Shetty, Sailakshmi Ganesan, Ashok Johari

“…Precise knowledge of magnitude and pattern of net joint moments and power along with the timing of moments and decline in walking distance in children with severe crouch, can guide therapeutic interventions to restore the optimum dynamic lever arm function for improved walking performance. Trial registration CTRI registration no. …”
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Gubi Decoction Ameliorates Porous Cartilage Endplate in an Intervertebral Disc Degeneration Model Mouse Through Inhibition of NF-&kappa;B Activity and Pyroptosis by Yao S, Li Y, Ruan H, Wu L, Zeng H

“…In parallel, GBD significantly improved the matrix metabolism-related indexes of IVD at 8 weeks after modeling. …”
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Synergistic effects of human umbilical cord mesenchymal stem cells/neural stem cells and epidural electrical stimulation on spinal cord injury rehabilitation by Zhiping Mu, Jiaodi Qin, Xiaohua Zhou, Kunzheng Wang

“…Abstract Spinal cord injury (SCI) is a severe neurological condition marked by a complex pathology leading to irreversible functional loss, which current treatments fail to improve. …”
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E2F1/CDK5/DRP1 axis mediates microglial mitochondrial division and autophagy in the pathogenesis of cerebral ischemia‐reperfusion injury by Ya‐Jing Yuan, Tingting Chen, Yan‐Ling Yang, Hao‐Nan Han, Li‐Ming Xu

“…Abstract Background The integrity of brain function is at stake due to cerebral ischemia‐reperfusion injury (CIRI), which encompasses mitochondrial dysfunction, autophagy, and neuroinflammation. …”
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Arthrodesis with Hybrid Nail-Frame Construct Allows for Expedited Frame Removal During Neuropathic Limb Salvage by William Polachek MD, Philip H. Locker MD, Jacob R. Zide MD, Veerabhadra Reddy MD, David Vier MD

“…Conclusion: Limb salvage in neuropathic patients is a resource intensive endeavor, however successful salvage reduces long term expenditures and may allow for improved patient function compared to amputation. Arthrodesis with hindfoot nail-frame constructs results in similar rates of stable fusion while reducing the amount of time required for external fixation by nearly a third. …”
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Unraveling the Role of Oxygen Pulse Variability in Endurance Exercise Training in Individuals with COPD: A Novel Approach to Response of Oxygen Pulse and Quality of Life in Pulmona... by Huang SY, Hsieh PC, Huang KL, Yang MC, Jao LY, Tzeng IS, Lan CC, Wu YK

“…However, improvements in O2P, maximal inspiratory pressure, and tidal volume at rest were observed only in Group 2 but not in Group 1.Conclusion: PR improves exercise capacity, HRQL and specific respiratory function in participants with COPD, regardless of baseline O2P levels. …”
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Targeting miRNA‐1a and miRNA‐15b: A Novel Combinatorial Strategy to Drive Adult Cardiac Regeneration by Ting Yuan, Meiqian Wu, Chaonan Zhu, Hao Yu, Minh Duc Pham, Katharina Bottermann, Yijie Mao, Yue Wang, Mathias Langner, Mirko Peitzsch, Arka Provo Das, Silke Kauferstein, Jonathan Ward, Peter Mirtschink, Andreas Michael Zeiher, Stefanie Dimmeler, Jaya Krishnan

“…Due to miRNA‐1a/15b function on multiple processes modulating adult cardiomyocyte mitosis, its inhibition augmented adult cardiomyocyte cell‐cycle completion and daughter cell formation, and improved contractility in 3D human cardiac organoids, and in a mouse model of ST‐segment elevation myocardial infarction. …”
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IMPACT-ICU feasibility study: pragmatic mixed-methods randomised controlled trial of a follow-up care intervention for survivors of critical illness and caregivers by Sunita Mathur, John Muscedere, David M Maslove, Miranda Hunt, John Gordon Boyd, Stephanie Sibley, Tracy Boyd, Michelle Tryon, Natasha Arianne Jawa, Michaela Hanley, Robin Westphal, Afolasade Fakolade

“…Introduction Survivors of critical illness and their caregivers are at risk for long-term cognitive, physical and psychiatric impairments known as post-intensive care syndrome (PICS) and PICS-family, respectively. …”
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How prior experience, cognitive skills and practice are related with eye-hand span and performance in video gaming by Markus Nivala, Agnes Cichy, Hans Gruber

“…Thirty-three participants played a platformer video game in a pre-test/practice/post-test experiment. Eye movements and keypresses were recorded. …”
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Correction of Midline Deviation and Unilateral Crossbite Treated with Fixed Appliance by Domenico Ciavarella, Marta Maci, Laura Guida, Angela Pia Cazzolla, Eleonora Lo Muzio, Michele Tepedino

“…At the end of the treatment, optimal functional and aesthetic results were obtained: realignment of the midline improved facial symmetry, correction of the crossbite on both sides, and a good occlusal relationship.…”
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A Study of Hypothyroidism in Chronic Kidney Disease (CKD) Patients by Sudharsanan V, Prabhu Shankar S, Viknesh V

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Associations of resuscitation fluid load, colloid-to-crystalloid infusion ratio and clinical outcomes in children with dengue shock syndrome. by Vo Thanh Luan, Vo Thi-Hong Tien, Ngo Thi-Mai Phuong, Do Chau Viet, Trinh Huu Tung, Nguyen Tat Thanh

“…The primary outcomes were the need for MV and renal function within 48 h post-admission. A predictive model for MV was developed based on covariates from the first 24 h of PICU admission. …”
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The implications of surgery on sexual dysfunction in patients with lumbar disc herniation with cauda equina syndrome: a systematic review by Zahra Moradi, Shadab Shahali, Fazlollah Ahmadi, Ali Montazeri

“…Conclusion Studies indicated a considerable enhancement in sexual function post-surgery for lumbar disc herniation patients (68% to 99%). …”
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