Renal tubular GSDME protects cisplatin nephrotoxicity by impeding OGT-STAT3-S100A7A axis in male mice by Qingzhou Chen, Pengxiao Sun, Jiaxin Zhou, Tantan Long, An Xiao, Zhuoliang Liu, Shihui Xu, Wenjing Lei, Rui Zhang, Jianwei Tian, Miaomiao Zhou, Zheng Hu, Fengxin Zhu, Jing Nie

“…Tubule-specific depleting S100a7a improves renal function and reduces renal injury and inflammation. …”
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Encapsulated Gambir catechin-palm fatty acid distillate as an antibacterial and antioxidant feed additive and its effects on rumen fermentation products by Roni Pazla, Antonius, Novirman Jamarun, Elihasridas, Zaitul Ikhlas, Yelly Fitri, Eni Siti Rohaeni, Usman, Otih Rostiana, Waryat, Setyadjit, Meivie Lintang, Alvi Yani, Gabriel Herald Joseph, Leni Marlina, Ardinal

“…Although encapsulation had no significant effect on fermentation characteristics, it improved dry matter digestibility and protected catechins in the rumen, enabling higher availability in the post-rumen. …”
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Inhibition of S100A8/A9 ameliorates neuroinflammation by blocking NET formation following traumatic brain injury by Guihong Shi, Yiyao Cao, Jianye Xu, Bo Chen, Xu Zhang, Yanlin Zhu, Liang Liu, Xilei Liu, Luyuan Zhang, Yuan Zhou, Shenghui Li, Guili Yang, Xiao Liu, Fanglian Chen, Xin Chen, Jianning Zhang, Shu Zhang

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Clinical Outcomes of All-Inside Arthroscopic Lateral Ankle Ligament Reconstruction for Chronic Lateral Ankle Instability: A Prospective Series with Minimum 12 Month Outcomes by Thomas L. Lewis BSc (Hons) MBChB (Hons) FRCS (Tr&Orth) MFSTEd, Vikram Vignaraja MBBS BSc (Hons) MRCS, Samuel Franklin MBBCh (Hons) MRCS, Gabriel Ferreira MD MSc PhD, Gustavo Araujo Nunes MD, Peter Lam MBBS (Hons), FRACS, FAOA, Robbie Ray MBChB, ChM(T&O), FRCSed(Tr&Orth), FEBOT

“…In all patients, there was significant improvement in all post-operative PROMs (p < 0.05). …”
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Subtilases: a major prospect to the genome editing in horticultural crops by Umashankar Chandrasekaran, Umashankar Chandrasekaran, Woo Jong Hong, Hyeran Kim, Hyeran Kim

“…Over the past five years, research on proteolytic enzymes, especially SBTs, has increased markedly, yet reports involving loss- or gain-of function analyses aimed at improving crop yield and quality are still limited. …”
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Moderate Ischemic Mitral Insufficiency at the Time of Coronary Artery Bypass Graft; Repair or Spare? by Ahmed Abdelwahhab, Mohamad Rushdi, Mohamed Ayyad, Ahmed Elminshawy

“…Mid-term outcomes included MR degree, LV diameter and function. Results: Groups had similar age and gender distribution. …”
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Effect of Intramuscular Injection of Vitamin D on 25-Hydroxyvitamin D Levels, Glycaemic Control, and Liver Enzymes in Libyan Patients with Type 2 Diabetes Mellitus by Hafsa M. Alemam, Mouna M. ElJilani, Abdulla M. Bashein

“…In addition, it has a positive effect on improving liver enzyme function. …”
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Pre-operative therapeutic eyelid hygiene in the prevention of complications following excimer laser vision correction by V. V. Kurenkov, A. V. Zhemchugova, E. G. Polunina, S. I. Abramov, A. A. Kozhuchov

“…In both groups, Natural tears and Systane Ultra (Alcon) were used as tear replacement therapy.Results: Complex treatment, including therapeutic eyelid hygiene in study group, significantly improved tear film and ocular sur- face health as well as meibomian glands functions. …”
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Comparative analysis of surgical techniques for pediatric diaphyseal forearm fractures: A focus on titanium flexible nails versus plates and screws by Fatemeh Shahrahmani, Reza Khosravi, Shahab Ilka, Sahar Heidarabadipour

“…Surgical duration, length of hospitalization, and complications were assessed post-surgery. Three months post-surgery, functional outcomes and fracture union time were evaluated. …”
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High-Performance YOLOv5s: Traffic Sign Detection Algorithm for Small Target by Mengxia Hu, Shengwen Pi, Jinying Zhou, Xinming Wan, Qiaoshou Liu

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Combined robot motor assistance with neural circuit-based virtual reality (NeuCir-VR) lower extremity rehabilitation training in patients after stroke: a study protocol for a singl... by Meng Ren, Xu-Yun Hua, Jia-Jia Wu, Jian-Guang Xu, Zhi-Qing Zhou, Jing-Jing Xu, Chun-Lei Shan

“…Introduction Improving lower extremity motor function is the focus and difficulty of post-stroke rehabilitation treatment. …”
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Changes in brain-derived neurotrophic factors in schizophrenic patients with spiritual psychoreligious therapy by Lilin Rosyanti, Indriono Hadi, Akhmad, Teguh Faturrahman, Arip Hidayat

“…Conclusion: Spiritual Quranic Emotional Freedom Technique therapy could enhance clinical improvement and brain function in schizophrenic patients. …”
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Efficacy of Cooling Blankets and Cold Fluid Infusions in Classic Heatstroke Treatment: A Controlled Study in Rats by Chen L, Liu C, Zhang Z, Zhang Y, Feng X

“…While cooling blankets demonstrate limited therapeutic efficacy and potential risks when used in isolation, rapid cold fluid infusion emerges as the preferred cooling modality by preserving cardiac structure and renal function while attenuating systemic inflammation. Early rapid cooling improves organ function and prognosis in classic heatstroke rats. …”
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Clinical efficacy observation of repetitive magnetic stimulation for treating upper limb spasticity after stroke by Zhifa Wang, Qing Liu, Dongxia Li, Ligang Wei, Erxing Chu, Yangdong Bao, Zhen Liu, Lei Jin, Xiaoxia Chen, Kai Zhao

“…Abstract To investigate the efficacy of repetitive transcranial magnetic stimulation (rTMS) for managing upper limb muscular spasticity after stroke, and to examine its therapeutic effects on spasticity and motor function in the upper limb. A total of 110 post-stroke patients with upper limb spasticity were randomly assigned to the experimental or the control group. …”
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Thymic peptides in immune reconstitution and clinical outcome after allogeneic hematopoietic cell transplantation by Hannah Kunstek, Janneke Kieviet, Caroline Lindemans, Coco de Koning, Stefan Nierkens

“…Furthermore, we summarize current reports on clinical application of thymic peptides post-HCT and discuss their potential use in improving patient outcomes.…”
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Noninfectious retrovirus particles drive the APOBEC3/Rfv3 dependent neutralizing antibody response. by Diana S Smith, Kejun Guo, Bradley S Barrett, Karl J Heilman, Leonard H Evans, Kim J Hasenkrug, Warner C Greene, Mario L Santiago

“…The lack of plasma virion infectivity was associated with a significant post-entry block during early reverse transcription rather than G-to-A hypermutation. …”
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Advancing immunomodulation in organ transplantation: the therapeutic potential of self-assembled rapamycin nanoparticles in allograft rejection by Ruiqi Sun, Zhi Liang, Ning Wang, Xiaona Chen, Jialing Zhao, Hong Tang, Wentao Zhao, Hangxiang Wang, Shusen Zheng, Penghong Song, Haiyang Xie

“…Additionally, in a rat orthotopic liver transplantation model, intermittent low-dose sRNP treatment (1 mg/kg every other day intravenously) effectively inhibited T cell proliferation, reduced inflammatory cell infiltration, markedly extended graft survival, and significantly improved liver function. Conclusions This study highlights sRNP’s superiority over oral RAPA in managing allograft rejection by enhancing immune regulation, reducing T cell differentiation, and decreasing inflammation. …”
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Progressive subchondral bone cyst formation following autologous chondrocyte implantation with all-suture anchors: a Case Report with histological evaluation by Takuma Kaibara, Eiji Kondo, Masatake Matsuoka, Koji Iwasaki, Tomohiro Onodera, Daisuke Momma, Zen-Ichi Tanei, Shinya Tanaka, Norimasa Iwasaki

“…Postoperative follow-up demonstrated successful integration of the osteochondral graft and improved knee function scores over three years. Conclusion This case report documents SBC formation following knee surgery with all-suture anchors and provides histological evaluation of such a cyst. …”
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Three cases of atypical Rasmussen's encephalitis with delayed‐onset seizures by Hongru Guo, Pan Gong, Guojing Yu, Chongyang Tang, Guoming Luan, Qingzhu Liu, Lixin Cai, Taoyun Ji

“…During 18 months of follow‐up, the patient's motor function improved, and no seizures occurred. Seizures are common initial symptoms of RE. …”
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Biomechanical Changes to the Ankle After Zadek Osteotomy by Nicholas Bellas MD, Raghunandan Nayak BS, Mehreen Pasha BS, Megan R. Wolf MD, Elifho Obopilwe MS, Thomas McDonald MD, Lauren E. Geaney MD

“…These results may explain the improvements in pain and function seen in clinical studies. …”
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