Effect of high-tone external muscle stimulation on fatigue and functional outcomes in multiple sclerosis: A randomized controlled trial by Khalid Taha Yassin Turky, Nevin M Shalaby, Asmaa Foad Abdelmonem, Tayseer Saber Abdeldayem, Mohammed Ali Mohammed Sarhan, Ghada S M Omar, Lama Saad El-Din Mahmoud

“…Both groups showed a significant improvement post-study compared with pre-study. There was a significant reduction in Disability Status Scale (p=0.002), Fatigue Severity Scale scores (p=0.004), and total scores of Modified Fatigue Impact Scale (p=0.001) of the study group compared with that of the control group. …”
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Functional characterisation of CD8+ T cells mobilised with acute supramaximal high‐intensity interval exercise: implications for immune surveillance by Anna Strömberg, Mirko Mandić, Brennan J Wadsworth, Sebastian Proschinger, Seher Alam, Lisa MJ Eriksson, Laura Barbieri, Eric Rullman, Helene Rundqvist

“…Importantly, CD8+ T cells maintained their viability and expansion properties despite the metabolic challenges induced by exercise. Functionally, post‐exercise CD8+ T cells showed increased release of IFN‐gamma and an enhanced unspecific cell killing capacity as demonstrated by co‐culture with the immortalised cell line HEK293T. …”
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Efficacy of Nusinersen Treatment in Type 1, 2, and 3 Spinal Muscular Atrophy: Real-World Data from a Single-Center Study by Anna Lemska, Piotr Ruminski, Jakub Szymarek, Sylwia Studzinska, Maria Mazurkiewicz-Beldzinska

“…SMA is classified into types 0 through 4 based on the age of symptom onset and the severity of motor function decline. Recent advances in SMA treatment, including nusinersen, onasemnogene abeparvovec, and risdiplam, have significantly improved the prognosis of SMA patients. …”
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Upper extremity function and disability recovery with vibration therapy after stroke: a systematic review and meta-analysis of RCTs by Yueh-Hsun Lu, Hung-Ju Chen, Chun-De Liao, Po-Jung Chen, Xin-Miao Wang, Chieh-Hsiang Yu, Po-Yin Chen, Chueh-Ho Lin

“…Abstract Background This study aimed to investigate the therapeutic effects of vibration therapy for improving upper extremity motor impairment, function, and disability recovery in people with stroke. …”
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Effects of external Chinese herbal therapy combined with pulse electromagnetic field on older adults with knee osteoarthritis: study protocol for a randomized controlled trial by Xiang Li, Foxiao Li, An Yu, Qi Bu, Ruirui Wang, Lijing Li, Wei Zhang, Lei Yang

“…However, no research has directly compared the efficacy of ECHT, PEMF, and their combined use on pain relief and functional improvement in older adults with KOA. This highlights a significant research opportunity to explore the comparative benefits of these treatment modalities.Methods and analysisThis randomized controlled trial (RCT) aims to enroll 124 older adults with KOA and will randomly allocate them across four treatment groups: (1) exercise with health education, (2) exercise with ECHT, (3) exercise with PEMF therapy, and (4) exercise with a combination of ECHT and PEMF. …”
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Motor Imagery during Action Observation of Locomotor Tasks Improves Rehabilitation Outcome in Older Adults after Total Hip Arthroplasty by Uros Marusic, Sidney Grosprêtre, Armin Paravlic, Simon Kovač, Rado Pišot, Wolfgang Taube

“…Of initially 405 screened participants, 21 were randomly split into intervention group (N=10; mean age = 64 y; AO + MI of locomotor tasks: 30 min/day in the hospital, then 3×/week in their homes for two months) and control group (N=11, mean age = 63 y, active controls). The functional outcomes (Timed Up and Go, TUG; Four Step Square Test, FSST; and single- and dual-task gait and postural control) were measured before (PRE) and 2 months after surgery (POST). …”
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Efficacy and safety of moxibustion treatment for upper extremity pain disorder and motor impairment in patients with stage I post-stroke shoulder-hand syndrome: a systematic review... by Xiaonan Meng, Xiaonan Meng, Jie Sun, Xintong Su, David Jung Seto, David Jung Seto, Liping Wang, Ying Li, Haikuo Yu, Baixiao Zhao, Jiping Zhao

“…There was no significant difference in the occurrence of adverse events (AEs) between corresponding experimental and control groups (RR = 1.62, 95% CI: 0.63, 4.16, p > 0.05).ConclusionThis study demonstrates that moxibustion as an adjuvant therapy may play a positive role in relieving pain and improving upper extremity motor function for patients with stage I SHS, given its convenience in generating prolonged effects in communities. …”
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Nifedipine and losartan effects on endothelial function during acute pharmacological test in arterial hypertension patients with various risk factors by M. O. Argunova, A. G. Avtandilov

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Effects of oral lycopene supplementation on vascular function in patients with cardiovascular disease and healthy volunteers: a randomised controlled trial. by Parag R Gajendragadkar, Annette Hubsch, Kaisa M Mäki-Petäjä, Martin Serg, Ian B Wilkinson, Joseph Cheriyan

“…At baseline, CVD patients had impaired EDV compared with HV (30% lower; 95% CI: -45% to -10%, P = 0.008), despite lower LDL cholesterol (1.2 mmol/L lower, 95% CI: -1.6 to -0.9 mmol/L, P<0.001). Post-therapy EDV responses for lycopene-treated CVD patients were similar to HVs at baseline (2% lower, 95% CI: -30% to +30%, P = 0.85), also suggesting lycopene improved endothelial function.…”
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A systematic review of alterations in sensorimotor networks following stroke: implications for integration and functional outcomes across recovery stages by Nur Shaheera Aidilla Sahrizan, Noorazrul Yahya, Zhe Kang Law, Wan Asyraf Wan Zaidi, Umi Nabilah Ismail, Naela Himayati Afifah, Amirul Azri, Hanani Abdul Manan, Hanani Abdul Manan

“…Despite initial impairments, most studies reported improvement in SMN connectivity over time, attributed to compensatory mechanisms, cortical reorganisation, and functional rewiring. …”
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Clinical feasibility and cortical effects of synchronous mirror therapy on speech-language and upper limb motor function after stroke by Shuo Xu, Wenrong Wang, Chenfang Liang, Shaofan Chen, Zhiming Huang, Xiaokun Li, Yanjuan Chen, Xiaoting Lin, Yilong Zou, Jie Jia, Haoqing Jiang

“…The results indicate potential benefits of SMT in improving language and UL motor function for post-stroke patients. fNIRS findings suggest possible enhanced cortical activation during SMT, which may be associated with neural recovery processes. …”
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Metabolic Effects of Sodium Thiosulfate During Resuscitation from Trauma and Hemorrhage in Cigarette-Smoke-Exposed Cystathionine-γ-Lyase Knockout Mice by Maximilian Feth, Felix Hezel, Michael Gröger, Melanie Hogg, Fabian Zink, Sandra Kress, Andrea Hoffmann, Enrico Calzia, Ulrich Wachter, Peter Radermacher, Tamara Merz

“…In mice with a genetic deletion of the H₂S-producing enzyme cystathione-γ-lyase (CSE^−/−), providing exogenous H₂S using sodium thiosulfate (Na₂S₂O₃) improved organ function after chest trauma and hemorrhagic shock. …”
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Open pilot study of a guided digital self-help intervention targeting sleep and the biological clock in university students using a pre-test post-test design by Laura M. Pape, Niki Antypa, Philip Spinhoven, Annemieke van Straten, Sascha Y. Struijs, Caring Universities Consortium

“…Study completers (n = 39) showed large improvements in insomnia severity (p < 0.001, d = 1.04), and moderate improvements in depression (p < 0.001, d = 0.63), anxiety (p < 0.001, d = 0.35), and functioning (p < 0.001, d = 0.56). …”
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Quick sequential organ failure assessment score combined with other sepsis-related risk factors to predict in-hospital mortality: Post-hoc analysis of prospective multicenter study... by Ryo Ueno, Takateru Masubuchi, Atsushi Shiraishi, Satoshi Gando, Toshikazu Abe, Shigeki Kushimoto, Toshihiko Mayumi, Seitaro Fujishima, Akiyoshi Hagiwara, Toru Hifumi, Akira Endo, Takayuki Komatsu, Joji Kotani, Kohji Okamoto, Junichi Sasaki, Yasukazu Shiino, Yutaka Umemura

“…Other key statistic values were similar among all models, with sensitivity and specificity of 0.55-0.65 and 0.60-0.75, respectively. In this post-hoc data analysis from a prospective multicenter study based in Japan, combining qSOFA with other sepsis-related risk factors only marginally improved the model's predictive value.…”
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Delayed remote ischemic postconditioning improves long term sensory motor deficits in a neonatal hypoxic ischemic rat model. by Pradilka N Drunalini Perera, Qin Hu, Junjia Tang, Li Li, Margaret Barnhart, Desislava M Doycheva, John H Zhang, Jiping Tang

“…Neurobehavioral tests, brain weights, gross and microscopic brain tissue morphologies, and systemic organ weights were evaluated at five weeks post surgery.<h4>Results</h4>HI induced rats performed significantly worse than sham but both groups of delayed RIPC treatment showed improvement of sensory motor functions. …”
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Indoor High Precision Three-Dimensional Positioning System Based on Visible Light Communication Using Improved Hybrid Bat Algorithm by Yong Chen, Han Zheng, Huanlin Liu, Zhaozhong Han, Zhimiao Ren

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Feasibility of Smartphone-Based Exercise Training Integrated with Functional Electrical Stimulation After Stroke (SETS): A Preliminary Study by Rudri Purohit, Juan Pablo Appelgren-Gonzalez, Gonzalo Varas-Diaz, Shuaijie Wang, Matias Hosiasson, Felipe Covarrubias-Escudero, Tanvi Bhatt

“…Participants also showed pre-post improvements in all measures of gait and balance function (<i>p</i> < 0.05). …”
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Improved DSSC performance with acidic extract of Euphorbia milii red flower, the effect of pH variation and DFT analysis of phytoconstituents by Nikhil Srivastav, Kalpajyoti Dihingia, Himanshu Patel, Yoganand Singh, Ananya Rai, Biswajit Maiti, Pankaj Srivastava

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Preliminary Effects of Extended Reality-Based Rehabilitation on Gross Motor Function, Balance, and Psychosocial Health in Children with Cerebral Palsy by Onebin Lim, Yunhwan Kim, Chanhee Park

“…Outcome measures included the Gross Motor Function Measure-88 (GMFM-88), Pediatric Balance Scale (PBS), Functional Independence Measure (FIM), Parenting Stress Index (PSI), and Pediatric Quality of Life Inventory (PedsQL), assessed pre- and post-intervention. …”
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Effectiveness of Structural Couple Therapy and Intensive Short-Term Dynamic Psychotherapy on Intrapersonal-Interpersonal Skills and Family Function in Couples by Nayereh Sadat Sadatmand, Ozra Etemadi, Fatemeh Bahrami, Maryam Fatehizadeh

“…Objective: The current investigation sought to evaluate the efficacy of structural couple therapy in conjunction with Intensive Short-Term Dynamic Psychotherapy (ISTDP) regarding the enhancement of intrapersonal-interpersonal skills and family function of couples. Methods: The research methodology employed was a quasi-experimental design incorporating pre-test and post-test assessments alongside a control group. …”
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