Ambulatory Catheter-based Interscalene Block for Proximal Humerus Fracture Rehabilitation: Safety, Efficacy and Lessons from a Pilot Study by Nah MFK, Seng ZQ, Tan YJB

“…Introduction: Proximal humerus fractures (PHFs) are associated with morbidity/functional impairment. Rehabilitation adherence is crucial to regain independent function yet is often hindered by pain. …”
Get full text

Assessment of an integrated therapeutic protocol for sheep with acute ruminal impaction: diagnostic and prognostic significance of rumen functions and hepatorenal biomarkers by Enas Elmeligy, Ebtsam S. Abdel-lah, Abdulaziz H. Almuhanna, Eman A. R. Abdelghffar, Eman A. R. Abdelghffar, Mustafa Shukry, Mahmoud Saber, Ashraf M. Abu-Seida, Sayed Fathi El-Hawari, Sayed Fathi El-Hawari, Laila A. Al-Shuraym, Lamya Ahmed Alkeridis, Khaled A. Khesruf, Arafat Khalphallah

“…The investigated sheep had a full clinical examination and hemato-biochemical tests from day 0 (pre-therapy) up to day’s 3–90 post-therapy.Results and conclusionThe applied therapeutic regimen (1–5 days’ therapeutic program) was highly effective in cases of acute ruminal impaction in sheep, as evidenced by a clear improvement in their clinical health status (up to 15 days post-therapy) as well as restoring their reference intervals of ruminal functions biomarkers, blood picture indices, and hepatorenal functions throughout the current study (15–60 days post-therapy). …”
Get full text

A decrease in functional microbiomes represented as Faecalibacterium affects immune homeostasis in long-term stable liver transplant patients by Soon Kyu Lee, JooYeon Jhun, Seung Yoon Lee, Sukjung Choi, Sun Shim Choi, Myeong Soo Park, Seon-Young Lee, Keun-Hyung Cho, A Ram Lee, Joseph Ahn, Ho Joong Choi, Young Kyoung You, Pil Soo Sung, Jeong Won Jang, Si Hyun Bae, Seung Kew Yoon, Mi-La Cho, Jong Young Choi

“…This study aimed to document the functional microbiome affecting immune homeostasis in long-term post-liver transplantation (LT) patients. …”
Get full text

Effects of the High-Intensity Early Mobilization on Long-Term Functional Status of Patients with Mechanical Ventilation in the Intensive Care Unit by Chuanlin Zhang, Xueqin Wang, Jie Mi, Zeju Zhang, Xinyi Luo, Ruiying Gan, Shaoyu Mu

“…The aim of this study was to investigate whether high-intensity early mobility improves post-ICU discharge functional status of IMV patients. …”
Get full text

A window into the mind-brain-body interplay: Development of diagnostic, prognostic biomarkers, and rehabilitation strategies in functional motor disorders. by Marialuisa Gandolfi, Angela Sandri, Sara Mariotto, Stefano Tamburin, Anna Paolicelli, Mirta Fiorio, Giulia Pedrotti, Paolo Barone, Maria Teresa Pellecchia, Roberto Erro, Sofia Cuoco, Immacolata Carotenuto, Claudia Vinciguerra, Annibale Botto, Lucia Zenere, Elisa Canu, Elisa Sibilla, Massimo Filippi, Elisabetta Sarasso, Federica Agosta, Michele Tinazzi, Group Collaborators Consortium

“…<h4>Background and aims</h4>Functional motor disorders (FMD) present a prevalent, yet misunderstood spectrum of neurological conditions characterized by abnormal movements (i.e., functional limb weakness, tremor, dystonia, gait impairments), leading to substantial disability and diminished quality of life. …”
Get full text

The impact of reduced skeletal muscle mass at stroke onset on 3-month functional outcomes in acute ischemic stroke patients. by Kyong Young Kim, Seunguk Jung, Eun Bin Cho, Tae-Won Yang, Seung Joo Kim, Hyunsung Kim, Sunhye Jung

“…This study aims to evaluate the effect of RMM at stroke onset on 3-month functional outcomes in acute ischemic stroke patients.…”
Get full text

Understanding oncological and sexual function outcomes with gynaecological organ preserving cystectomy in women with bladder cancer; a systematic review by Rebecca Martin, Harriet Wylie, Charlotte Moss, Shaista Hafeez, Pardeep Kumar, Anne Marie Rafferty, Mieke Van Hemelrijck

“…While SF initially declined, recovery improved over time, with Female Sexual Function Index (FSFI) scores exceeding the 26.2 dysfunction threshold in two studies by 12 months. …”
Get full text

Using Ecological Momentary Assessment to Assess Family Functioning in Spanish-Speaking Parent and Adolescent Dyads: Daily Questionnaire Study by Alejandra Fernandez, Savannah Bernal, Lana Kim, Subodh Potla

“… Abstract BackgroundFamily functioning is associated with several adolescent health outcomes, and many family-based interventions (FBIs) exist to improve family functioning. …”
Get full text

Effect of fixed dental prosthesis on the brain functions of partially edentulous patients – pilot study with power spectrum density analysis by Uddipta Prafulla Saikia, N. Gopi Chander, Muthukumar Balasubramanian

“…Power spectral density (PSD) analysis of EEG alpha waves was made pre- treatment, post treatment and 3 months after FDP treatment to analyse the brain function. …”
Get full text

Impact on physical function of the +AGIL Barcelona program in community-dwelling older adults with cognitive impairment: an interventional cohort study by Cristina Arnal, L Monica Pérez, Luís Soto, Álvaro Casas Herrero, Joan Ars, Sonia Baró, Francisco Díaz, Araceli Abilla, M Belén Enfedaque, Matteo Cesari, Marco Inzitari

“…Physical performance was measured at baseline, three and six months follow-up. The pre-post impact on physical function was assessed by paired sample t-test for repeated samples. …”
Get full text

Machine Learning Framework for Conotoxin Class and Molecular Target Prediction by Duc P. Truong, Lyman K. Monroe, Robert F. Williams, Hau B. Nguyen

“…We have previously demonstrated that the inclusion of post-translational modifications, collisional cross sections values, and other structural features, when added to the standard primary sequence features, improves the prediction accuracy of conotoxins against non-toxic and other toxic peptides across varied datasets and several different commonly used machine learning classifiers. …”
Get full text

Peculiarities of children’s health status after acute respiratory viral infections: a look at the problem, ways to solve it by Yu.V. Marushko, T.V. Marushko, O.A. Dmytryshyn, O.A. Bovkun, T.V. Iovitsa, B.Ya. Dmytryshyn

“…The persistence of these manifestations hinders the adequate restoration of the child’s adaptive capacity and the fight against hypoxia, acidosis, metabolic disorders due to ARVI, and post-viral asthenic syndrome. This determines the urgency of finding appropriate methods of correction with etiopathogenetic (inhibition of oxidative stress, reduction of acidosis and hypoxia, restoration of liver function), immunoregulatory (improvement of the immune system), and symptomatic (improvement of appetite) effects. …”
Get full text

Top-Down Dual-Interface Carrier Management for Highly Efficient and Stable Perovskite/Silicon Tandem Solar Cells by Xin Li, Zhiqin Ying, Shuo Li, Lei Chen, Meili Zhang, Linhui Liu, Xuchao Guo, Jun Wu, Yihan Sun, Chuanxiao Xiao, Yuheng Zeng, Jian Wu, Xi Yang, Jichun Ye

“…Highlights An innovated top-down dual-interface carrier management strategy is developed to effectively improve both interfaces of the wide-bandgap perovskite using a multi-functionalized piperazinium chloride post-treatment. …”
Get full text

Autophagy-enhancing strategies to promote intestinal viral resistance and mucosal barrier function in SARS-CoV-2 infection by Anusca G. Rader, Alexandra P.M. Cloherty, Kharishma S. Patel, Dima D.A. Almandawi, Jimena Perez-Vargas, Manon E. Wildenberg, Vanesa Muncan, Renée R.C.E. Schreurs, François Jean, Carla M.S. Ribeiro

“…In addition, the autophagy blockers restored the barrier function of infected intestinal epithelium. In this addendum, using human intestinal organoids, we present evidence for a protective role of intrinsic higher levels of autophagy flux in limiting intestinal SARS-CoV-2 infection. …”
Get full text

Effect of family-oriented interviews on family function of young persons attending the family practice clinic in Oauthc, Ile Ife, south-western Nigeria by Akinjide O. Ogundokun, Emmanuel A. Abioye-Kuteyi, Ibrahim S. Bello, Olanrewaju O. Oyegbade, Samuel A. Olowookere, Akintunde J. Olowookere

“…Family-oriented interview may have significantly improved perceived family function in the study. Family-oriented interview of young persons presenting for medical care is recommended.…”
Get full text

Fibroblasts‐specific p16INK4a exacerbates inflammageing‐mediated post‐infarction ventricular remodelling through interacting with STAT3 to regulate NLRP3 transcription by Xin Gu, Yingqiang Du, Jin'ge Zhang, Jiyu Li, Haiyun Chen, Yujie Lin, Yue Wang, Chunli Zhang, Shiyu Lin, Nannan Hao, Chengyi Peng, Jiacheng Ge, Jin Liu, Yan Liang, Yongjie Zhang, Xiaoyan Wang, Fang Wang, Jianliang Jin

“…POSTN‐driven p16INK4a knockout improved cardiac function, and reduced ventricular remodelling, myocardial inflammation and NLRP3 signalling activation following MI through downregulating STAT3‐mediated NLRP3 inflammasome and upregulating glutathione metabolism pathway in fibroblasts. …”
Get full text

Radiological Healing Patterns and Functional Outcomes After Conservative Treatment of Unilateral Condylar Fractures: A Report of Two Cases by Edoardo Staderini, Irene Cavalcanti, Anna Schiavelli, Patrizia Gallenzi, Gabriele Di Carlo, Massimo Cordaro

“…The radiological healing patterns were associated with slightly different functional outcomes. Both patients also exhibited an improvement in skeletal asymmetry and TMJ function. (4) <b>Conclusions:</b> According to the findings in the present study, the condylar remodeling and bone apposition after conservative treatment of condylar fractures in growing patients can exhibit different radiological and functional outcomes. …”
Get full text

Evaluation of the clinical effectiveness of bundled care interventions on pressure ulcer incidence in neurosurgical patients by Ai-Hua Lv, Xi Zhang, Xiu-Ling Sun, Xiu-Lan Liu, Jun-Qing Qi, Hui-Na Li

“…Emotional functioning also improved significantly, with the study group scoring 85.32 ± 2.05 compared to 76.41 ± 2.12 in the control group. …”
Get full text

CEST imaging combined with 1H-MRS reveal the neuroprotective effects of riluzole by improving neurotransmitter imbalances in Alzheimer’s disease mice by Yuanyu Shen, Xiaolei Zhang, Siqi Liu, Lijing Xin, Wentao Xuan, Caiyu Zhuang, Yue Chen, Beibei Chen, Xinhui Zheng, Renhua Wu, Yan Lin

“…Conclusions CEST imaging combined with 1H-MRS demonstrated the effectiveness of riluzole in modulating Glu- and GABA-related changes and improving cognitive function in 3xTg AD mice, potentially through regulating key proteins involved in neurotransmitter metabolism. …”
Get full text

Improved Sleep Associated With Triamcinolone Acetonide Extended-Release Injections for Knee Osteoarthritis: Use of a New Real-World Registry by Michael A. Mont, MD, Jennifer H. Lin, PhD, Andrew I. Spitzer, MD, Vinod Dasa, MD, Adam Rivadeneyra, MD, David Rogenmoser, DO, Andrew L. Concoff, MD, Mitchell K. Ng, MD, Mary DiGiorgi, PhD, MPH, Stan DySart, MD, Joshua Urban, MD, William M. Mihalko, MD, PhD

“…Patient demographics were gathered/analyzed, adjusting for age, sex, study site, Kellgren-Lawrence grade, baseline score of pain severity/function, pain-catastrophizing, and analgesic use in each assessment. …”
Get full text