Construction and validation of frailty risk prediction model in elderly patients with colorectal cancer by Yuxiao Xia, Mengzhang He, Yiqun Guo, Fenghua Zhang, Xiongting Wu, Rong Chen, Linli Duan, Fang Chen, Xuewei Yang, Xiuli Feng

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Regulation of plant gene expression by tsRNAs in response to abiotic stress by Chunmei Li, Jing Zhu, Han Jin, Haotian Feng, Haimin Zhuang, Zijun Du, Guolin Zhu, Haiyang He, Fuyang Ye, Zhaohui Mo, Qingtao Hu, Zhenbang Chen, Kai Liu, Xiaorong Wan

“…This review aims to summarize recent advances in the classification, biogenesis, and biological functions of tsRNAs, with a focus on their roles in plant stress responses and the methodologies for investigating these molecules. …”
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Abstract 055: Reperfusion Therapy for Acute Ischemic Stroke in Cardiomyopathy Patients with Heart Failure: A NIS‐based Analysis by Serena Wong, Bridget Dolan, Fawaz Al‐Mutfi, Brittany Russo, Chaitanya Medicherla, Kevin Clare, Aiden Liu

“…We hypothesized that CM and HF patients would have higher rates of mortality and complications but would still benefit from reperfusion therapy with improved functional outcomes. Methods This is a multi‐center, retrospective study. …”
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THE USE OF CRYOCONSERVATED PLACENTA FOR PREVENTION OF PATHOLOGIC SCAR FORMATION OF THE HEAD AND NECK AT THE INTRA- AND POSTOPERATIVE STAGE IN PLANNED SURGERY by O.A. Toropov, D.S. Avetikov, K.P. Lokes, D.V. Steblovskyi, V.M. Skrypnyk, R.A. Prykhidko

“…Multiple studies report a significant scar thickness improvement when applying the right program. Conclusion. …”
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A mechanism-based group psychotherapy approach to aggressive behavior (MAAP) in borderline personality disorder: a multicenter randomized controlled clinical trial by Christine Sigrist, Andreas Bechdolf, Katja Bertsch, Robin Bullenkamp, Martin Busse, Ute gr. Darrelmann, Astrid Dempfle, Martin Driessen, Thomas Frodl, Jan-Michael Kersting, Jessica Kesik, Burkhart Matzke, Corinne Neukel, Eva Niessen, Svenja Nückel, Viola Oertel, Frank Padberg, Alexandra Philipsen, Dorothee Pink, Andreas Reif, Matthias Reinhard, Carolin Steuwe, Larissa Wolkenstein, Sabine C. Herpertz, the MAAP Consortium

“…In BPD, patterns of reactive aggression often lead to functional impairment affecting important areas of life. …”
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Deciphering the tumor ecosystem dynamics undergoing immunochemotherapy therapy across multiple cancer types unveils the immunosuppressive role of S100A4 in fibroblasts by promoting... by Bo Yang, Bo Yang, Ruiji Chen, Ruiji Chen, Mali Zu, Jie Yao, Hong Ren, Hong Ren, Yingxue Lin, Yingxue Lin, Bo Zhang, Tianjiao Ji, Yang Liu

“…BackgroundNeoadjuvant therapy (NAT) has transformed cancer treatment by improving surgical outcomes and survival rates, yet resistance mechanisms across multiple cancer types remain unclear. …”
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About relevance of fundamentalisation of mathematical training of students of the pedagogical directions during the digital era by E. A. Perminov, D. D. Gadjiev, M. M. Abdurazakov

“…Introduction. The era of post-industrial society of knowledge differs from the previous socio-economic period in many important aspects: total digitalisation, automation and robotisation, and furthermore, cross-disciplinary integration of various scientific fields, among which mathematics is of particular relevance. …”
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Implementation of group interpersonal therapy to treat depression in people living with HIV: A first evaluation of IPT dissemination in Senegal by Hawa Abou Lam, Hélène Font, Véronique Petit, Salaheddine Ziadeh, Judicaël Malick Tine, Ibrahima Ndiaye, Ndeye Fatou Ngom, Babacar Ndiaye, Daniel Sarr, Dominique Diouf, Nathalie de Rekeneire, Antoine Jaquet, Moussa Seydi, Charlotte Bernard, the IeDEA West Africa Cohort Collaboration

“…Depressive symptoms severity (PHQ-9) and functioning (WHODAS) were measured pre-, post-treatment and at 3-month follow-up. …”
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Genome-Wide Identification of <i>G3BP</i> Family in U’s Triangle <i>Brassica</i> Species and Analysis of Its Expression in <i>B. napus</i> by Alain Tseke Inkabanga, Qiheng Zhang, Shanshan Wang, Yanni Li, Jingyi Chen, Li Huang, Xiang Li, Zihan Deng, Xiao Yang, Mengxin Luo, Lingxia Peng, Keran Ren, Yourong Chai, Yufei Xue

“…The RasGAP SH3 domain binding protein (G3BP) is a highly conserved family of proteins in eukaryotic organisms that coordinates signal transduction and post-transcriptional gene regulation and functions in the formation of stress granules. …”
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Tenecteplase thrombolytic therapy for acute ischaemic stroke in China: a real-world, multicentre, retrospective, controlled study by Peng Li, Qiang Dong, Anqi Zhang, Qiang Li, Hong Zhang, Yibin Fang, Ye Liu, Gang Li, Hui Luo, Xiaoyu Zhou, Chao Wu, Dan li, Yu Yao, Kun Fang, Xiangjun Li, Yin Liu, Jingyu Guo, Huaying Wang, Jianjun Tang, Xin Cheng, Jianhong Yang, Lan Hong, Guozhi Lu, Guang Wu, Rongbo Qu, Yongren Fang, ZhiJiao He, Lian Zuo, Jinchun Wang, Dongya Huang, Ge-Fei Li, Yanzhang Xiao, Zongyan Dang, Yeqiu Jiao, Yang Zhu, Yulei Deng, Linghao Cao

“…A higher proportion of patients achieving early neurological improvement at 24 hours (OR: 1.76, 95% CI: 1.48 to 2.09, p=0.000), better 90-day mRS (OR: 0.67, 95% CI: 0.57 to 0.79, p=0.000) as well as higher percentages of 90-day mRS 0–1 (OR: 1.27, 95% CI: 1.05 to 1.54, p=0.012) and mRS 0–2 (OR: 1.41, 95% CI: 1.14 to 1.75, p=0.001) compared with alteplase.Conclusions Thrombolysis with TNK is not associated with an increased risk of sICH, and may result in better early neurological improvement and 90-day functional outcomes compared with alteplase in patients with AIS.…”
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Left ventricle myocardial remodeling following septal myectomy in patients with hypertrophic obstructive cardiomyopathy by Guanyu Lu, Liqi Cao, Jiehao Ou, Xinyi Luo, Wei Zhu, Zhicheng Du, Jian Liu, Yuelong Yang, Xinyue Zhang, Peijian Wei, Hongxiang Wu, Huiming Guo, Hui Liu

“…These changes were accompanied by improvement of New York Heart Association functional class, 6-min walk test results, N-terminal pro-B-type natriuretic peptide, and high-sensitivity cardiac troponin T. …”
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CAR-T cells and TRUCKs that recognize an EBNA-3C-derived epitope presented on HLA-B*35 control Epstein-Barr virus-associated lymphoproliferation by Michael Hudecek, Anna Christina Dragon, Katharina Zimmermann, Thomas Nerreter, Deborah Sandfort, Julia Lahrberg, Stephan Klöß, Christina Kloth, Caroline Mangare, Agnes Bonifacius, Sabine Tischer-Zimmermann, Rainer Blasczyk, Britta Maecker-Kolhoff, Barbara Uchanska-Ziegler, Hinrich Abken, Axel Schambach, Britta Eiz-Vesper

“…Of note, TÜ165 TRUCKs with inducible IL-12 showed highly improved effector functions and additionally led to recruitment of monocyte and NK cell lines.Conclusions Our results demonstrate that TÜ165 CAR-Ts recognize EBV peptide/HLA complexes in a TCR-like manner and thereby allow for recognizing an intracellular EBV target. …”
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Time dependency of thrombectomy for large artery atherosclerosis versus cardioembolic stroke subtypes: evidence from the ANGEL-ACT registry by Yue Yin, Hanlin Chen, Anxin Wang, Anxin Wang, Anxin Wang, Xiaoli Zhang, Xiaoli Zhang, Xiaoli Zhang, Miao Li, Ligang Song, Ligang Song, Ligang Song, Baixue Jia, Baixue Jia, Baixue Jia, Ning Ma, Ning Ma, Ning Ma, Dapeng Mo, Dapeng Mo, Dapeng Mo, Xuan Sun, Xuan Sun, Xuan Sun, Feng Gao, Feng Gao, Feng Gao, Yiming Deng, Yiming Deng, Yiming Deng, Zhongrong Miao, Zhongrong Miao, Zhongrong Miao

“…Methods: Study participants were selected from the Endovascular Treatment Key Technique and Emergency Workflow Improvement of Acute Ischemic Stroke Registry to conduct a post-hoc analysis of a prospective, observational study. …”
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Ecological resources of a heavily modified and utilised temperate coastal embayment: Cockburn Sound by Peter J. Mitchell, Daniel E. Yeoh, Kurt N. Krispyn, Claire N. Greenwell, Sorcha Cronin-O’Reilly, Delphine B.H. Chabanne, Glenn A. Hyndes, Danielle Johnston, David V. Fairclough, Claire Wellington, Alan Cottingham, Gary Jackson, Jeffrey V. Norriss, Matias Braccini, Hector Lozano-Montes, Chandra P. Salgado Kent, Erin Clitheroe, Alissa Tate, James W. Penn, Marion Massam, Neil R. Loneragan, James R. Tweedley

“…Nevertheless, while still biodiverse, there are signs of considerable ecological stress from escalating anthropogenic pressures and the cumulative impacts of ongoing and future developments, including climate change, which may severely impact the functioning of this important ecosystem.…”
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EarthRanger: An open‐source platform for ecosystem monitoring, research and management by Jake Wall, Jes Lefcourt, Chris Jones, Chris Doehring, Dan O'Neill, Dennis Schneider, Jordan Steward, Joshua Krautwurst, Tiffany Wong, Bruce Jones, Karen Goodfellow, Ted Schmitt, Kathleen Gobush, Iain Douglas‐Hamilton, Frank Pope, Eric Schmidt, Jonathan Palmer, Emma Stokes, Andrea Reid, L. Mark Elbroch, Peter Kulits, Catherine Villeneuve, Victor Matsanza, Geoff Clinning, Jordi vanOort, Kristen Denninger Snyder, Alina Peter Daati, Wesley Gold, Stephen Cunliffe, Batian Craig, Barry Cork, Grant Burden, Marc Goss, Nathan Hahn, Sarah Carroll, Eric Gitonga, Ray Rao, Jared A. Stabach, Frédéric Dulude‐de Broin, Patrick Omondi, George Wittemyer

“…EarthRanger consists of seven main components (Core Server, API, Storage, Gundi, Web App, Mobile App, Ecoscope) that provide functionality for data (i) aggregation & collection, (ii) storage & management, (iii) real‐time and post hoc analysis, (iv) visualisation and (v) dissemination. …”
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Phenotypic evaluation of worldwide germplasm of arugula (Eruca sativa Mill.) and identification of underlying latent factors contributing to phenotypic variation under indoor farmi... by Seam Choon Law, Ting Xiang Neik, Ethan Tze Cherng Lim, Adrian Ming Jern Lee, Yi Lin Lim, Wan Zu Tang, Shuang Song, Pei-Wen Ong, Sin Joe Ng, Fook Tim Chew

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Development mechanism and practical significance of deep coalbed methane (coal rock gas) infiltration and displacement by Lihong ZHOU, Xia YAN, Hongtao LIU, Xianyue XIONG, Feng WANG, Shuguang LI, Jiyuan ZHANG, Chuanqing LIU, Xiong HU, Pu YUAN, Qianli MA, Xueguang ZHU

“…For 2 nm pores under reservoir and post-fracturing pressure conditions, strong hydrophilic (30° contact angle) and weakly hydrophilic (70°) pores generated capillary forces exceeding 40.1 MPa and 15.8 MPa, respectively, creating intense imbibition driving forces. …”
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Clarifying confusions over carbon conclusions: antecedent soil carbon drives gains realised following intervention by Albert Muleke, Matthew Tom Harrison, Rowan Eisner, Maria Yanotti, Peter de Voil, Shah Fahad, Wang Fei, Puyu Feng, Carla Ferreira, Daniel Forster, Xionghui Gao, Ke Liu, Jianguo Man, Lixiao Nie, Jiangwen Nie, Zhiming Qi, Narasinha Shurpali, Weilu Wang, Rui Yang, Xiaogang Yin, Feng Zhang, Yunbo Zhang, Jin Zhao

“…We contend that (1) management interventions primarily impacted SOC in the soil surface (0–30 cm) and had de minimus impact on deep SOC stocks (30–100 cm), (2) crop rotations including wheat, canola and faba beans were more conducive to improvement in SOC stocks, (3) scenarios with high status quo SOC had little impact on crop productivity, and not necessarily the lowest GHG emissions intensity, (4) productivity and GHG emissions intensity were largely a function of the quantum of nitrogenous fertiliser added, rather than SOC stocks, and (5) aspirations for improving SOC are likely to be futile if antecedent SOC stocks are already high (4–5 %). …”
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A randomised controlled trial of amygdala fMRI-neurofeedback versus sham-feedback in borderline-personality disorder – systematic literature review and introduction to the BrainSTE... by Christian Paret, Miroslava Jindrová, Nikolaus Kleindienst, Judith Eck, Hester Breman, Michael Lührs, Beatrix Barth, Thomas Ethofer, Andreas J. Fallgatter, Rainer Goebel, Andreas Hoell, Denise Lockhofen, Annika S. Reinhold, Simon Maier, Swantje Matthies, Christoph Mulert, Christian Schönholz, Ludger Tebartz van Elst, Christian Schmahl

“…Trial registration The study protocol was first posted 2024/10/04 on ClinicalTrials.gov and received the ID NCT06626789.…”
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Dietary mixtures of Bacillus spp. modulates intestinal morphology, resistance to Vibrio parahaemolyticus, response of immune-antioxidant genes, and growth of Dicentrarchus labrax by El-Sayed Hemdan Eissa, Afaf N. Abdel Rahman, Ragaa A. Ahmed, Basma M. Hendam, Yasmin M. Abd El-Aziz, Hagar Sedeek Dighiesh, Moaheda E.H. Eissa, Ekemini Moses Okon, Norhan H. Ahmed

“…From overall results, MBs (3 g/kg diet) are recommended in European seabass to promote growth rate, feed utilization, immune-antioxidant status, and V. parahaemolyticus resistance without any hazardous impact on liver functions. These advantageous gains may help to ensure a sustainable aquaculture.…”
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