Intraoperative virtual reality for older patients undergoing total knee arthroplasty: study protocol for a randomized clinical trial by Juan P. Espinosa-Leon, Ryan Mathura, Guanqing Chen, Melisa Joseph, Trishna Sadhwani, Najla Beydoun, Edjay R. Hernandez, Tyler Riley, Lisa J. Kunze, Valerie Goodspeed, Brian P. O’Gara

“…Secondary outcomes include patient satisfaction, post-anesthesia care unit (PACU) length of stay, postoperative pain scores and analgesic requirements, functional outcomes, postoperative delirium, and postoperative neurocognition. …”
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Head-to-head comparison of 68Ga-PSMA-11 and 18F-FDG in delayed PET/CT imaging in prostate cancer diagnosis by Biyao Hu, Haonan Yu, Meijie Pan, Meijie Pan, Hailei Yang, Xiling Xing, Dong Li, Shaobo Yao, Shaobo Yao, Qiusong Chen

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Long‐term outcomes of electrical storm patients listed for urgent heart transplantation but not transplanted acutely by Miloud Cherbi, Philippe Maury, Léa Benabou, Maxime Faure, Matteo Pozzi, Laurent Sebbag, Estelle Gandjbakhch, Karim Benali, Pierre Groussin, Redwane Rakza, Raphael P. Martins, Clément Delmas

“…Finally, five (12.5%) were removed from the HTx waiting list due to functional improvement, distinguished by a median LVEF of 45.0% (20.0%–45.0%). …”
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Longitudinal study on quality of life following cervical cancer treatment in Botswana by Natalie Taylor, Doreen Ramogola-Masire, Karen Canfell, Katharine A Rendle, Lesego Gabaitiri, Surbhi Grover, Nicola Zetola, Memory Bvochora-Nsingo, Sebathu Chiyapo, Dawn Balang, Lilie L Lin, Mark N Polizzotto, Erle Robertson, Salman Khan, Rohini K Bhatia, Shalini Vinod, Paseka Tladi

“…Per QLQ-C30, the mean global health status score (72.21 vs 78.37; p<0.01) and the symptom (12.70 vs 7.63; p=0.04) and functional scales (88.34 vs 91.85; p<0.01) improved significantly from the EOT to the 24 month follow-up for all patients; however, using the QLQ-Cx24 survey, no significant differences in the symptom burden (12.53 vs 13.67; p=0.6) or functional status (91.23 vs 89.90; p=0.53) were found between these two time points.Conclusion The QoL increased significantly for all patients undergoing CRT, underscoring the value of pursuing curative CRT, regardless of the HIV status.…”
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Endovascular therapy and medical management of large-core infarcts: prognostic determinants in a retrospective cohort by Yi Li, Yi Li, Hao Tao, Hao Tao, Huan Liu, Huan Liu, Xiang Fan, Xiang Fan, Meng-Yu Zhong, Meng-Yu Zhong, Jie Huang, Neng-Wei Yu, Neng-Wei Yu, Bing-Hu Li, Bing-Hu Li

“…In the EVT subgroup (n = 62), hyperglycemia remained significantly associated with poor outcomes (OR = 1.70, 95% CI: 1.04–2.78, p = 0.034).ConclusionEVT significantly improves functional outcomes in large-core infarcts. …”
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Comprehensive Structural, Chemical, and Optical Characterization of Cu₂ZnSnS₄ Films on Kapton Using the Automated Successive Ionic Layer Adsorption and Reacti... by Perla J. Vázquez-González, Martha L. Paniagua-Chávez, Lizette A. Zebadua-Chavarria, Rafael Mota-Grajales, C. A. Meza-Avendaño, Enrique Campos-González, A. Escobosa-Echavarría, Yaoqiao Hu, Aldo E. Pérez-Ramos, Manuel-Matuz, Carlos A. Hernández-Gutiérrez

“…A pole figure analysis indicates a decrease in texture disorder with annealing, suggesting improved crystalline orientation at higher temperatures. …”
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Analgesic efficacy and safety of erector spinae plane block versus serratus anterior plane block in breast surgery—a meta-analysis and systematic review of randomized controlled tr... by Samiullah Shaikh, Umm E Salma Shabbar Banatwala, Paranshi Desai, Muhammad Arham Khan, Rimsha Bint-e-Hina, Sidra Samad, Muhammad Hamza Sikandari, Ali Nawaz, Rana Ijaz, Shayan Asmat, Abeer Fatima, Harim Mirza, Noor Mahal Azam, Qurat Ul Ain Muhammad, Satesh Kumar, Mahima Khatri

“…Many undergoing breast surgery experience postoperative pain compromising their functionality and quality of life. While multiple pain management strategies are available, evidence comparing the erector spinae (ESPB) and serratus anterior plane blocks (SAPB) for improving post-surgical pain management in breast cancer surgery patients is limited. …”
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Comprehensive analysis of lactylation-related gene and immune microenvironment in atrial fibrillation by Yazhe Ma, Youcheng Wang, Yuanjia Ke, Yuanjia Ke, Yuanjia Ke, Qingyan Zhao, Qingyan Zhao, Qingyan Zhao, Jie Fan, Yang Chen

“…Immune infiltration plays a crucial role in AF pathogenesis, yet its mechanisms remain unclear. Lactylation, a novel post-translational modification, has been implicated in immune regulation, but its association with AF remains unexplored. …”
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Efficacy of Different Doses of Intra‐Articular Tranexamic Acid for Reducing Blood Loss and Lower Limb Swelling After Total Knee Arthroplasty: A Prospective, Randomized, Controlled... by Shuwei Ye, Yue Luo, Qianhao Li, Lijun Cai, Pengde Kang

“…One‐way analysis of variance (ANOVA), post hoc Bonferroni correction, Pearson chi‐square test and Fisher exact test were used for statistical analysis. …”
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Feasibility of a Web-Based and Mobile-Supported Follow-Up Treatment Pathway for Adult Patients With Orthopedic Trauma in the Netherlands: Concurrent Mixed Methods Study by Gijs J A Willinge, Jelle F Spierings, Kim A G J Romijnders, Elke G E Mathijssen, Bas A Twigt, J Carel Goslings, Ruben N van Veen

“…Semistructured interviews were performed at 10‐12 weeks post injury. Anonymous data from a pre-existing database were used to compare health care resource use between the digital treatment pathways and traditional treatment. …”
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Impact of the COVID-19 pandemic on outcomes of acute ischemic stroke patients treated with endovascular therapy: A multicenter Canadian study. by Shenghua Zhu, Ammar Alam, Rebecca Thornhill, Vered Tsehmaister-Abitbul, Grant Stotts, Hailey Pettem, Richard Aviv, Ronit Agid, Aleksandra Pikula, Jai Jai Shiva Shankar, Genevieve Milot, Brian Van Adel, Samuel Yip, Manraj Heran, Robert Fahed, Fabio Settecase, Marlise P Dos Santos

“…Patients were more likely to have favourable outcomes (mRS at 90 days score of ≤ 2) post-EVT pre-pandemic than pandemic (53% vs 44%; p = 0.02). …”
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Design and Evaluation of Real-Time Data Storage and Signal Processing in a Long-Range Distributed Acoustic Sensing (DAS) Using Cloud-Based Services by Abdusomad Nur, Yonas Muanenda

“…We employ the DynamoDB functionality of Amazon Web Services (AWS), which allows highly expandable storage capacity with latency of access of a few tens of milliseconds. …”
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The effect of acute beetroot juice consumption prior to climbing on lower-body isokinetic and isometric strength, aerobic power, and muscle soreness among mountain climbers by Alireza Daneshparvar, Mohammad Hemmatinafar, Mohsen Salesi, Rasoul Rezaei, Babak Imanian, Sepideh Pirmohammadi

“…One week later, during the climbing session, they consumed 70 mL of BRJ (400 mg nitrate), PLA, or water 2.5 hours before ascending to 3720 meters. Functional tests (HJ, wall-sit, and estimated VO₂max) were performed at the altitude. …”
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Tribological properties of polymer like carbon coatings on NBG-18 nuclear graphite under nitrogen environment by HAN Hai, LIU Huichuan, CHENG Jinjuan, CHEN Xinchun, LIU Pengxiao, QI Wei, TANG Xian

“…Simultaneously, the lubrication and failure mechanisms of the PLC coatings were investigated.ResultsThe experimental results demonstrate a significant increase in the hardness of NBG-18 nuclear graphite, from 0.44 GPa to 4.16 GPa, marking an 845% improvement post-PLC coating deposition. The elastic modulus rose from 9.00 GPa to 27.21 GPa, reflecting a 202% enhancement. …”
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WABAH CORONA DAN UNGGAHAN DI INSTAGRAM: ANALISIS KOMPONEN TINDAK TUTUR by Anak Agung Ayu Dian Andriyani, I Gusti Agung Sri Rwa Jayantini

“…Various posts aimed to provide current information, to suggest people to listen to the government's rules to stay at home, practice social restriction, improve healthy lifestyle as well as give criticism concerning lack of discipline behavior. …”
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In Vitro Evaluation of the Efficient Passage of PLGA-Formulated Trastuzumab for Nose-to-Brain Delivery by Léa Kengne Kamkui, Clémence Disdier, Amaury Herbet, Narciso Costa, Anne-Cécile Guyot, Didier Boquet, Aloïse Mabondzo

“…Importantly, the TZB released from the nanoparticles retained all of its physicochemical properties and functionality. We observed that the NP-TZB formulation results in at least a nine-fold increase in TZB permeability across the nasal epithelium 24 h post-exposure, depending on the exposure conditions, but shows no significant improvement across the BBB model. …”
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POSSIBILITIES OF SURGICAL CORRECTION OF INTERNAL CAROTID ARTERY THROMBOSIS IN PATIENTS WITH ACUTE ISCHEMIC STROKE by V. A. Lukyanchikov, E. V. Udodov, N. A. Polunina, A. S. Tokarev, V. A. Dalibaldyan, O. Y. Nakhabin, E. V. Grigoryeva, Y. I. Shatokhina, N. Y. Kudryashova, G. K. Guseynova, E. A. Khodykin, V. G. Dashyan, V. L. Lemenyov, V. V. Krylov

“…The excellent outcomes were seen in 7 (33.4%) patients, good outcomes — in 11 (52.3%) and satisfactory outcomes were observed in 3 (14.3%) patients. The improvement of functional deficit in the early post-operative period was 4.85 scores according to NIHSS, 1.2 scores according to Rankin scale and 2.3 scores according to Rivermead mobility index. …”
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Network Pharmacology Approaches to Myocardial Infarction Reperfusion Injury: Exploring Mechanisms, Pathophysiology, and Novel Therapies by Joy Das, Ashok Kumar Sah, Ranjay Kumar Choudhary, Rabab H. Elshaikh, Utpal Bhui, Shreya Chowdhury, Anass M. Abbas, Manar G. Shalabi, Nadeem Ahmad Siddique, Raji Rubayyi Alshammari, Navjyot Trivedi, Khoula Salim Ali Buwaiqi, Said Al Ghenaimi, Pranav Kumar Prabhakar

“…The pathophysiology of MIRI involves complex, interrelated mechanisms including oxidative stress, calcium overload, mitochondrial dysfunction, inflammatory responses, apoptosis, and dysregulated autophagy. Post-reperfusion recovery is further complicated by structural and functional abnormalities such as microvascular obstruction, endothelial dysfunction, and myocardial stunning. …”
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Metabolomics and proteomics insights into hepatic responses of weaned piglets to dietary Spirulina inclusion and lysozyme supplementation by Cátia Falcão Martins, Manolis Matzapetakis, David M. Ribeiro, Josipa Kuleš, Anita Horvatić, Nicholas Guillemin, Peter David Eckersall, João P. B. Freire, André M. Almeida, José A. M. Prates

“…This includes fewer differentially expressed proteins and improved dry matter, organic matter and energy digestibility. …”
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The influence of dental occlusion on hamstring muscle isokinetic parameters in active competitive soccer athletes: a randomized controlled trial by Stine Hecht, Yoon Jeong Choi, Andrea Stroux, Florian Beuer, Manja von Stein-Lausnitz, Till E. Bechtold

“…IntroductionThe improvement of athletic performance depends on numerous factors including physical health, training status, neuromuscular coordination and psychological state. …”
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