Selumetinib in Adult Neurofibromatosis 1 with Plexiform Neurofibroma by Carlen A. Yuen, Eleanor Chu, Ryan O’Connell, Bryan K. Sun, Raj Vyas, Michelle Zheng, Emma Elliott, Changrui Xiao

“…<b>Background/Objectives:</b> Neurofibromatosis Type 1 (NF1) plexiform neurofibroma (PN) can cause morbidity, including disfigurement that can negatively impact social functioning. Historically, the mainstay treatment is surgical resection. …”
Get full text

Development and evaluation of spirometry reference equations at high altitude by Yanyan Li, Zhenzhen Xing, Xiangda Zhang, Yanlu Hu, Yanfei Guo

“…The reference equations utilise age and height as independent variables, with improved accuracy achieved through spline functions. …”
Get full text

The Effectiveness of Sand Play Therapy on Social Skills and Adaptation of Children with Separation Anxiety by Ehsan Kazemi, Meisam Ashrafi, Maryam Sadat Hosseinzadeh Maryam Sadat Hosseinzadeh, Zahra Andalibipour, Shohreh Rajab Ali, Mehran Mohebian Far Mehran Mohebian Far

“…Objective: The aim of this current research was to examine the effectiveness of sand play therapy in improving the social skills and adjustment of children experiencing separation anxiety. …”
Get full text

Boxe4Ageing: Investigating the Effects of Boxing and Multicomponent Training on Health of Older Adults – A Quasi-Experimental Study Protocol by Kessketlen Alves-Miranda, Simão Pedro-Costa, Ewetton de Souza Bezerra, José Oliveira, Lucimere Bohn

“… Introduction: Physical exercise is essential for maintaining functionality and independence in later life. However, the specific benefits of boxing as a form of exercise remain unclear. …”
Get full text

Boxe4Ageing: Investigating the Effects of Boxing and Multicomponent Training on Health of Older Adults – A Quasi-Experimental Study Protocol by Kessketlen Alves-Miranda, Simão Pedro-Costa, Ewetton de Souza Bezerra, José Oliveira, Lucimere Bohn

“… Introduction: Physical exercise is essential for maintaining functionality and independence in later life. However, the specific benefits of boxing as a form of exercise remain unclear. …”
Get full text

CXCL10 and IL15 co-expressing chimeric antigen receptor T cells enhance anti-tumor effects in gastric cancer by increasing cytotoxic effector cell accumulation and survival by Siyue Nie, Yujie Song, Kun Hu, Wei Zu, Fengjiao Zhang, Lixia Chen, Qiang Ma, Zishan Zhou, Shunchang Jiao

Get full text

Metaverse Support Groups for LGBTQ+ Youth: An Observational Study on Safety, Self-Expression, and Early Intervention by Joe Hasei, Yosuke Matsumoto, Hiroki Kawai, Yuko Okahisa, Manabu Takaki, Toshifumi Ozaki

Get full text

Multifunctional dietary approach reduces intestinal inflammation in relation with changes in gut microbiota composition in subjects at cardiometabolic risk: the SINFONI project by Hugo Hornero-Ramirez, Arianne Morissette, Bruno Marcotte, Armelle Penhoat, Béryle Lecomte, Baptiste Panthu, Jacob Lessard Lord, Florence Thirion, Laurie Van-Den-Berghe, Emilie Blond, Chantal Simon, Cyrielle Caussy, Nathalie Feugier, Joël Doré, Philippe Sanoner, Alexandra Meynier, Yves Desjardins, Geneviève Pilon, André Marette, Patrice D. Cani, Martine Laville, Sophie Vinoy, Marie-Caroline Michalski, Julie-Anne Nazare

Get full text

Current advances in the development of microRNA-integrated tissue engineering strategies: a cornerstone of regenerative medicine by Luis Germán Castañón-Cortés, Luis Alberto Bravo-Vázquez, Grecia Santoyo-Valencia, Sara Medina-Feria, Padmavati Sahare, Asim K. Duttaroy, Sujay Paul

“…Regenerative medicine is an innovative scientific field focused on repairing, replacing, or regenerating damaged tissues and organs to restore their normal functions. A central aspect of this research arena relies on the use of tissue-engineered scaffolds, which serve as structural supports that mimic the extracellular matrix, providing an environment that orchestrates cell growth and tissue formation. …”
Get full text

Structured Comparison Approach in Remote Interprofessional Education: Enhancing Role Clarity and Collaborative Identity Through Video-Based Reflection by Ysuhisa Nakamura, Kazuko Ando, Kyoko Otani, Mayumi Yoshikawa, Ayako Furuzawa

“…In the first session, the students independently assessed a video case using the International Classification of Functioning, Disability and Health (ICF) core sets. …”
Get full text

Preventing muscle loss through early mobilization in non-critically ill older adults admitted to surgical intensive care units by Onuma Chaiwat, Thanadol Wachiramatee, Benjaporn Sathitkarnmanee, Suchera Rattanamung, Piyapat Dajpratham, Napat Thikom, Chayanan Thanakiattiwibun

“…Early mobilization did not significantly alter muscle strength or mass but safely increased mobilization intensity, reduced infections, and improved short-term functional outcomes in older SICU patients. …”
Get full text

Effect of electroacupuncture on restoration of traumatic vertebral compression fracture: two case studies and literature review by Ji-Sung Yeum, Ye-Rim Yun, No-Hyun Kim, Jong-Ho Choi, Do-Young Kim, Do-Young Kim

“…Both patients experienced marked pain relief and functional improvements. Their NRS scores decreased from 70 to 40 (patient 1) and 30 (patient 2), ODI scores decreased from ∼85 to 64.4 and 42.2, respectively, and EQ-5D scores improved to 67.7 (patient 1) and 73.0 (patient 2). …”
Get full text

Long-term effectiveness of a multicomponent frailty management program in Singapore: One-year preliminary findings of a cluster-randomised controlled trial by Tianma Xu, Rhin Tok, Yan Ying Tay, Shi Ting Lai, Grace Hui Ling Tan

“…There was no significant difference found in most outcome measures between groups across all time points. Fall reduction post-intervention was observed. SNTF demonstrated potential long-term effectiveness in improving frailty status, physical functions, self-efficacy, community participation, quality of life and fall reduction in the community-dwelling older adults with pre-frailty and frailty in Singapore, regardless of the training background of the program facilitators.…”
Get full text

Application of ferrofluids for enhanced oil recovery: Impact on heavy and light oils in heterogeneous and homogeneous micromodels by Milad Khashay, Tarek Ganat, Ehsan Esmaeilnezhad

“…Additionally, their magnetic properties allow for easy post-recovery separation, enhancing environmental sustainability and reusability. …”
Get full text

Clinical outcomes of a novel single-stage cartilage repair technique using calcified cartilage zone debridement with hyalofast. by Badrul Akmal Hisham Md Yusoff, Muhammad Ikmal Hazli, Norlelawati Mohamad, Muhamad Karbela Reza Ramlan, Nik Kamarul Arif Bin Nik Kamrulzaman, Mohamed Razzan Rameez, Mohamad Azwan Aziz

“…Patients were followed up at baseline, 1, 6, and 18 months post-operative, using visual analog scale, KOOS, IKDC, and Lysholm Score.…”
Get full text

An Energy-Efficient Dynamic Feedback Image Signal Processor for Three-Dimensional Time-of-Flight Sensors by Yongsoo Kim, Jaehyeon So, Chanwook Hwang, Wencan Cheng, Jong Hwan Ko

“…Furthermore, These functionalities are designed for hardware-efficient implementation, improving processing speed and minimizing power consumption. …”
Get full text

Transbuccal films in veterinary medicine: a comparative study of the effect of dosage forms on clinical and biochemical parameters of blood by Arfenya S. Karamyan, Georges Bannud

“…In modern veterinary pharmacology and therapy, the ability to control the dosage, delivery, release of the drug, as well as minimal fixation of the animal and absence of post-injection reactions are extremely important. …”
Get full text

Market Regime Identification and Variable Annuity Pricing: Analysis of COVID-19-Induced Regime Shifts in the Indian Stock Market by Mohammad Sarfraz, Guglielmo D’Amico, Dharmaraja Selvamuthu

“…Advanced methodologies, including regime-switching hidden Markov models, artificial neural networks, and Monte Carlo simulations, were applied to analyze pre- and post-COVID-19 market behavior. The regime-switching hidden Markov models effectively capture latent market regimes and their transitions, which traditional models often overlook, while neural networks provide flexible functional approximations that enhance pricing accuracy in highly non-linear environments. …”
Get full text

Presymptomatic microRNA-based biomarker signatures for the prognosis of localized radiation injury in mice. by Lucie Ancel, Jules Gueguen, Guillaume Thoër, Jules Marçais, Aïda Chemloul, Bernard Le Guen, Marc Benderitter, Radia Tamarat, Maâmar Souidi, Mohamed Amine Benadjaoud, Stéphane Flamant

“…These results suggest miRNA profiling could be a powerful tool for early LRI diagnosis, thereby improving patient management and treatment outcomes in radiological emergency situations.…”
Get full text

Effectiveness of resistance training on resilience in Hong Kong Chinese older adults by Ming Yu Claudia Wong, Chun-Qing Zhang, Yanan Zhao, Chun Hu, Kailing Ou

“…The effects on resilience, functional fitness, and quality of life were measured immediately after the intervention and 12 weeks later. …”
Get full text