Effects of Osteocalcin on Synthesis of Testosterone and INSL3 during Adult Leydig Cell Differentiation by Gulfidan Coskun, Leman Sencar, Abdullah Tuli, Dilek Saker, Mustafa Muhlis Alparslan, Sait Polat

“…After evaluation of findings altogether, it is put forward that, for the first time in this study, although osteocalcin treatment made no significant difference in the number of Leydig cells, it increased the level of testosterone through improving the function of existing adult Leydig cells during normal postnatal development process and post-EDS regeneration. …”
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Regulation of plant immunity through histone H3 β-hydroxybutyrylation-mediated transcriptional control by Qiutao Xu, Zhengting Chen, Rui Wang, Xuan Ma, Yuhang Duan, Du Hai, Jing Chen, Zhongyi Cheng, Lu Zheng, Junbin Huang, Jisen Zhang, Yu Zhao, Xiaoyang Chen

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Assessment of Vitamin A versus Vitamin E effect on Motility and DNA Integrity of Human Cryopreserved Sperms by Samir Al-Anbari, Mustafa Ibraheem, Thaer Farhan

“… Background: It is well known that cryopreservation procedure may result in negative impact on spermatozoa function throughout relative overproduction of reactive oxygen species (ROS). …”
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Outcomes of liver transplantation in the era of modern antiviral therapy for hepatitis C by K. Yu. Kokina, Yu. O. Malinovskaya, Ya. G. Moysyuk

“…In the non-AVT group, one patient showed improved liver function (11.1%); in the rest, MELD/Na either remained stable or continued to increase - 44.5% (n = 4). …”
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Diethyl nitrosamine-induces neurobehavioral deficit, oxido-nitrosative stress in rats' brain: a neuroprotective role of diphenyl diselenide by Solomon Owumi, Joseph Chimezie, Praise Dyap Emmanuel, Anthony Chukwuma Okeibuno, Olatunde Owoeye

“…DPDS treatment (pre- and post-DEN exposure) significantly alleviated these neurotoxic, oxidative, and nitration effects, reversed DEN-induced histopathological alterations, and improved locomotive and cognitive functions. …”
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Impact of Enterococcus faecium AL41 on growth performance, immune parameters, morphology, and tight junction proteins in intestine of chicks by Levkut Martin, Karaffová Viera, Grešáková Ľubomíra, Čechová Michaela, Faixová Zita, Szabóová Renáta, Rudolf Žitňan, Róbert Herich

“…Our trial indicated that early administration of EFAL41after hatching affects growth performance improves health function as intestinal morphology, barrier integrity of gut and intestinal immunity.…”
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CircSpna2 attenuates cuproptosis by mediating ubiquitin ligase Keap1 to regulate the Nrf2‐Atp7b signalling axis in depression after traumatic brain injury in a mouse model by Mengran Du, Jiayuanyuan Fu, Jie Zhang, Ziyu Zhu, Xuekang Huang, Weilin Tan, Lian Liu, Zhijian Huang, Xin Liu, Qiuhao Tan, ZhengBu Liao, Yuan Cheng

“…The overexpression of circSpna2 also improved mitochondrial function and synaptic integrity, which are typically impaired by copper dysregulation. …”
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Effects of Incremental Shuttle Walk Test on Maximal Oxygen Consumption and Comfort in Patients with Coronary Artery Disease Undergoing Phase 3 Cardiac Rehabilitation by Mutarobin Mutarobin, Tutiany Tutiany

“…Coronary artery disease (CAD) is a condition characterized by impaired cardiac function due to a reduced blood supply to the myocardial tissue, resulting from narrowing or obstructing of the coronary arteries. …”
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Genicular Nerve Ultrasound-Guided Cryoanalgesia for the Treatment of Chronic Knee Joint Pain: An Observational Retrospective Study by Giuliano Lo Bianco, Francesco Paolo D’angelo, Guillherme Ferreira Dos Santos, Agnes Stogicza, Matteo Luigi Giuseppe Leoni, Andrea M. Trescot, Robert Jason Yong, Christopher L. Robinson

“…Clinical outcomes were assessed at baseline and at 1, 3, 6, and 9 months post-procedure. Outcome measures included the Visual Analog Scale (VAS, 0–10) for pain intensity, the Western Ontario and McMaster Universities Arthritis Index (WOMAC, 0–100) for assessing pain, stiffness, and physical function related to OA, the Douleur Neuropathique en 4 Questions (DN4, 0–10) for neuropathic pain, and the EuroQol 5-Dimension (EQ-5D, 0–100) for quality of life. …”
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Local government response to urban biodiversity conservation challenges within a global biodiversity hotspot by Cameron T. McLean, Cameron T. McLean, Debra C. Roberts, Debra C. Roberts, Debra C. Roberts, Rob Slotow

“…Development of land management and restoration functions have further advanced conservation outcomes through restored ecological processes, and improved management of threats. …”
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Long-Term Effect of Semaglutide on the Glomerular Filtration Rate Slope in High-Risk Patients with Diabetic Nephropathy: Analysis in Real-World Clinical Practice by Enrique Luna, Álvaro Álvarez, Jorge Rodriguez-Sabiñón, Juan Villa, Teresa Giraldo, Maria Victoria Martín, Eva Vázquez, Noemi Fernández, Belén Ruiz, Guadalupe Garcia-Pino, Coral Martínez, Lilia Azevedo, Rosa María Diaz, Nicolas Roberto Robles, Guillermo Gervasini

“…<b>Results:</b> In the whole study population, the median eGFR slope significantly improved from −3.29 (IQR 7.54) to −0.79 (IQR 6.01) mL/min/1.73 m²/year post-treatment (<i>p</i> < 0.001). …”
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Clinical investigation on nebulized human umbilical cord MSC-derived extracellular vesicles for pulmonary fibrosis treatment by Meng Li, Huaping Huang, Xiaofei Wei, Huajuan Li, Jun Li, Bingchen Xie, Yuze Yang, Xingyue Fang, Lei Wang, Xiaona Zhang, Heyu Wang, Mengdi Li, Yuting Lin, Dezhi Wang, Yinyin Wang, Tongbiao Zhao, Jianqiu Sheng, Xinbao Hao, Muyang Yan, Lu Xu, Zhijie Chang

“…Patients receiving the combined therapy of nebulized hUCMSC-EVs and routine treatment demonstrated significant improvements in both lung function indices (forced vital capacity and maximal voluntary ventilation) and respiratory health status (as measured by the Saint George’s Respiratory Questionnaire and Leicester Cough Questionnaire. …”
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Breathing therapy for patients with medically unexplained physical symptoms and dysfunctional breathing: A pilot and feasibility trial. by Hege Svenningsen, Trine Stub, Rosalba Courtney, Tor-Ivar Karlsen

“…At 3 months post-intervention, sustained improvements were seen in dysfunctional breathing, general well-being, musculoskeletal pain, and additionally lower pseudoneurological, gastrointestinal, and allergy complaints, as well as lower overall symptom burden and improved end-tidal CO2 levels. …”
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Features of coronary heart disease in a cohort of tajik patients and the condition of the vascular endothelium in its different clinical forms by F. A. Shukurov, M. S. Tabarov

“…In recent decades, there has been great interest among research scientists in studying the functioning of the endothelium in various forms of coronary heart disease, as well as in individuals with post-infarction cardiosclerosis as a complication of coronary heart disease. …”
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Comparison of the effects of different physical stimulation therapies on reducing upper limb spastic paralysis and motor dysfunction in stroke survivors after stroke: a network met... by Mingtong Bian, Mingtong Bian, Fuyan Chen, Fuyan Chen, Fuyan Chen, Huizhen Su, Zhiying Li, Zhiying Li, Xiaowei Sun, Xiaowei Sun, Yang Liu, Yang Liu, Jinyuan Shi, Jinyuan Shi, Shuo Liu, Shuo Liu, Ru Rong, Ru Rong

“…BackgroundUpper limb spasticity is a common and disabling sequela of stroke, which significantly impairing motor function and the capacity to perform activities of daily living (ADL). …”
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Optimization of Rosa roxburghii Tratt pomace fermentation process and the effects of mono- and mixed culture fermentation on its chemical composition by Xinxin Yi, Xinxin Yi, Shuo Zhang, Shuo Zhang, Duo Meng, Duo Meng, Jian Zhang, Jian Zhang, Chencen Lai, Chencen Lai, Min Zhang, Min Zhang, Xiaodong Sun, Xiaodong Sun, Haoxiang Yu, Pengjiao Wang, Pengjiao Wang, Xiuli Gao, Xiuli Gao, Xiuli Gao

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Tablet- and Group-Based Multicomponent Cognitive Stimulation for Older Adults With Mild Cognitive Impairment: Single-Group Pilot Study and Protocol for Randomized Controlled Trial by Khanitin Jornkokgoud, Pattrawadee Makmee, Peera Wongupparaj, Alessandro Grecucci

“…ResultsThe pilot study showed significant cognitive improvement (P<.001), reduced depression (P=.002), and decreased state anxiety (P=.001) post intervention. …”
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Impact of Life Skills Training on Distress Tolerance, Quality of Life, and Marital Conflicts in Married Students by Bahareh Boustani1, Mahin Eksir, Atefeh Pouraskar Borazjani4

“…Methods: This experimental design with a pre-test post-test setup along with a control group was conducted on married students enrolled at Shiraz Azad University in the first half of the year 2024. …”
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Production and Assessment of Biscuit from Wheat and Bambara Nut as Fat Substitute by Izuwa Iwanegbe, Joseph Oghenewogaga Owheruo

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Comparison of effectiveness of the addition of neuromuscular electrical stimulation of quadriceps muscle to standard rehabilitation protocol of ACL reconstruction by Anamika Lohiya, Himanshu Kataria, Himanshu Gupta, Diganta Bohra, Vineet Jain

“…Neuromuscular electrical stimulation (NMES) activates muscles in precise sequence and magnitude to directly accomplish functional tasks. This prospective comparative study compared the outcomes of rehabilitation post-ACLR with and without NMES.Methods: A total of 70 post-ACLR patients were divided into 2 groups. …”
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