Impact of intermediate-dose tertiary prophylaxis on quality of life and psychological aspects of adult patients with severe/moderate hemophilia A by Hua Gao, Jia Liu, Shiqiu Zhou, Jing Gao, Jing Tan, Rong Chen

“…Better functional independence correlates with improved quality of life. …”
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Safety helmet detection methods in heavy machinery factory by Liu Baoju, Wei Xiangqian, Chen Qingshan, Liu Jiaqi, Chen Ye, Yu Peng, Lei shi, Hu Yongfeng

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Research on IoT security situation awareness method based on evidence theory by Jian LI, Tinglu DONG, Jie LI

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Pro-repair macrophages driven by CGRP rescue white matter integrity following intracerebral hemorrhage by Huaping Huang, Yirui Kuang, Yang Chen, Yi Zhang, Jiayin Zhou, Xian Yu, Yonghe Zheng, Lingxin Cai, Wanglu Hu, Liansheng Gao, Haijian WU, Hui Ling, Xiao Dong, Hang Zhou, Xiaobo Yu, Yucong Peng, Gao Chen, Xiaoyu Wang, Wei Yan

“…CGRP administration expanded THBS1-positive macrophages in the bone marrow and brain, improving WM integrity (reduced radial diffusivity, higher fractional anisotropy) and sensorimotor function. …”
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Acute haemodynamic impact of transcatheter aortic valve implantation in patients with severe aortic stenosis by Francesca Graziani, Pio Cialdella, Rosa Lillo, Gabriella Locorotondo, Lorenzo Genuardi, Gessica Ingrasciotta, Stefano Cangemi, Marialisa Nesta, Piergiorgio Bruno, Cristina Aurigemma, Enrico Romagnoli, Michele Calabrese, Nicole Giambusso, Antonella Lombardo, Francesco Burzotta, Carlo Trani

“…Post‐TAVI echo showed a significant reduction in LV end‐diastolic (P = 0.036) and end‐systolic (P ˂ 0.001) diameters, improvement in LV ejection fraction (from 55 ± 12% to 57.2 ± 10.5%, P ˂ 0.001), and pulmonary artery systolic pressure (42.1 ± 14.2 vs. 33.1 ± 10.7 mmHg, P < 0.001). …”
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Understanding the effectiveness and underlying mechanisms of lifestyle modification interventions in adults with learning disabilities: a mixed-methods systematic review by Dikshyanta Rana, Sophie Westrop, Nishant Jaiswal, Evi Germeni, Arlene McGarty, Louisa Ells, Phillippa Lally, Michael McEwan, Craig Melville, Leanne Harris, Olivia Wu

“…These interventions targeted anthropometric, cardiorespiratory, functional and general health outcomes. In RCTs, intervention effectiveness was mixed, leading to improvements in outcomes as well as instances of no change or worsened outcomes. …”
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Estimulación temprana como programa neurológico en las capacidades y destrezas en niños en etapa infantil by Ruth Narciza Zambrano Pintado, Hugo Luis Moncayo Cueva, Soraya Nathaly López Arcos, Diego Mauricio Bonilla Jurado

“…The results indicate that once the values of the instruments were used and analyzed in their phases I and II (pretest and post-test), in a period of time between each one of 6 months, improvements were observed in the participants in terms of development psychomotor and linguistic, showing that repetitions and reinforcements between the trident (children, educators and parents) are effective for the evolution of the minors evaluated. …”
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Adverse Tissue Reaction to Metal and Polyethylene Particles as the Major Underlying Pathogenesis in Revision Total Ankle Arthroplasty by Jensen Henry MD, Yaxia Zhang MD, PhD, Emily Teehan MS, Thomas W. Bauer MD, PhD, Constantine Demetracopoulos MD

“…Category: Ankle Arthritis; Basic Sciences/Biologics Introduction/Purpose: Recent advancements in prosthesis design and surgical techniques have improved the clinical outcomes of total ankle arthroplasty (TAA) for end-stage ankle arthritis, leading to pain relief and better function. …”
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Metabolic Health Consequences of Switching to the Bictegravir/Emtricitabine/Tenofovir Alafenamide and Dolutegravir Plus Lamivudine Regimens in Virologically Suppressed People Livin... by Shi J, Zhang W, Han J, Zhang Z, Yan D, Zheng R, Li F, Wang Y

“…All participants were examined the changes in weight, BMI, GLU levels, lipid parameters (TC, LDL-C, HDL-C, and TG), and eGFR at post-12-month.Results: The mean age of included participants was 50.8 years (SD: 11.3). …”
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Non-lethal sonodynamic therapy mitigates hypertensive renal fibrosis through the PI3K/AKT/mTORC1-autophagy pathway by DanDan Liu, Hui Wang, Jialong Li, Siqi Sheng, Shu Wang, Ye Tian

“…However, enhancing autophagy by activating the PI3K/AKT, AMPK, and mTOR pathways, improves podocyte injury and renal pathological changes, and ameliorates renal function. …”
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Engineered supercooling systems for enhanced long-term preservation of large-volume red blood cells in commercial blood bags by Qi Liu, Shichun Wang, Jie Yan, Ronghua Diao, Haishui Huang, Feng Xu, Chunyan Yao

“…This engineered protocol significantly reduces hemolysis, metabolic degradation, and oxidative stress while preserving RBC membrane integrity and functionality for up to 63 days. In vivo transfusion studies in New Zealand white rabbits demonstrate that supercooling-preserved RBCs achieve higher post-transfusion recovery rates, outperforming conventional storage methods. …”
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NGAL: An Upcoming Biomarker of Interest by Khushboo Jasotani, Kiran Dahiya, Raunak Ahlawat, Mohit Gupta, Sushil Kumar, Rakesh Dhankhar, Pragati Singh

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The role of extracellular vesicles in the diagnosis of glioblastoma progression by A. I. Ryabova, V. A. Novikov, N. V. Yunusova, A. A. Ponomareva, L. V. Spirina, O. V. Gribova

“…Current treatment of tumor recurrence allows to increase patient survival, improve functional outcome and decrease caregivers» load. …”
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Children’s perspectives on autonomous vehicles: A usability and user experience study in a high-fidelity prototype by Vanessa Stange, Kerstin Kuhlmann, Tobias Schräder, Leon Johann Brettin, Markus Maurer

“…Driverless or autonomous vehicles (AVs) have the potential to improve the mobility of children and young people without a driver’s license, who are currently dependent on adult drivers in everyday life. …”
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Tablet computer-based cognitive training for visuomotor integration in children with developmental delay: a pilot study by Jee Hyun Suh, Soo Jeong Han, Sun Ah Choi, Hyesung Yang, Sihyun Park

“…The primary visuomotor function was measured using the Beery-Buktenica Developmental Test of Visual-Motor Integration, 6th Edition (VMI-6). …”
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Multi-objective optimization placement strategy for SDN security controller considering Byzantine attributes by Tao WANG, Hongchang CHEN

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Central slip defect reconstruction utilizing partial ulnar side of flexor digitorum superficial tendon for chronic boutonniere deformity: A case report by Andriessanto Ceelvin Lengkong, Albertus Djarot Noersasongko, Haryanto Sunaryo, R. Tommy Suharso, Rangga B.V. Rawung, Stefan A.G.P Kambey, Alfons Datui

“…Background: Post-traumatic central slip injuries, resulting in boutonniere deformity, are a complex issue that can significantly impact hand function and quality of life. …”
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Optilume drug‐coated balloon for anterior urethral stricture: 2‐year results of the ROBUST III trial by Maia E. VanDyke, Allen F. Morey, Karl Coutinho, Kaiser J. Robertson, Richard D'Anna, Kent Chevli, Christopher H. Cantrill, Michael J. Ehlert, Alexis E. Te, Jeffrey Dann, Jessica M. DeLong, Ramón Virasoro, Judith C. Hagedorn, Richard Levin, Euclid DeSouza, David DiMarco, Brad A. Erickson, Carl Olsson, Sean P. Elliott

“…Primary efficacy endpoints measured at 2 years included freedom from re‐intervention and changes in IPSS, Qmax and post‐void residual (PVR). Secondary endpoint was impact on sexual function using the International Index of Erectile Function (IIEF). …”
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Synergistic combinations of Angelica sinensis for myocardial infarction treatment: network pharmacology and quadratic optimization approach by Wen-Di Wang, Xin-Yi Fan, Xiao-Qi Wei, Wang-Jing Chai, Fang-He Li, Kuo Gao, Bin Liu, Bin Liu, Shu-Zhen Guo

“…In vivo, Z-LIG/CGA significantly improved cardiac function and reduced the fibrotic area in mice post-MI, surpassing the results in groups treated with Z-LIG or CGA alone. …”
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Left atrial strain predicts paroxysmal atrial fibrillation recurrence after catheter ablation: a 1-year study using three-dimensional speckle-tracking echocardiography by Rui Zhang, He Li, Yan Wang, Tianle Yu, Jiacheng Li, Yumeng Wu, Zhiwen Yu, Cuixing Liang, Dan Yu, Li Xue

“…Conclusions RFCA plays a pivotal role in preserving SR and restoring LA function in patients with PAF. 3D-STE is highly effective for post-RFCA prognostic assessment. …”
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