Selective serotonin inhibitors and their perspectives in ophthalmology by E. Yu. Markova, E. G. Polunina, V. V. Kurenkov, M. L. Gadaeva

“…These data allow to include Dusopharm in the complex therapy of central retinal vein and its branches occlusion, diabetic retinopathy, age-related macular degeneration (AMD), glaucoma, peripheral retinal degeneration, and retinal detachment to improve and stabilize visual functions and microcirculation.…”
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N-glycosylation of ACTRIIB enhances protein stability leading to rapid cell proliferation and strong resistance to docetaxel in nasopharyngeal carcinoma by Qin Qin, Junfeng Li, Yinjian Shao, Lan Liu, Zhibin Luo

“…In conclusion, N-glycosylation of ACTRIIB was a critical post-translational modification that enhanced protein stability and induced membrane localization, which facilitates the functions of ACTRIIB in cell proliferation and invasion in NPC. …”
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The effect of six weeks hamstring eccentric exercises on the postural control ability and knee joint proprioception in adolescent football players. by Azita Mohamadi, Amir Letafatkar, Seyed Hosein Hosseini, Safoura Heshmati

“…Results: According to the results, there were no significant differences in the knee proprioception, dynamic postural control and hip flexion range of motion between the experimental and control groups in the pre-test (p> 0.05). In the post-test, there was no significant difference between the experimental and control groups in the knee active proprioception (p >0.05), but the knee passive proprioception (p = 0.014), dynamic postural control (P = 0.001) and hip flexion range of motion (p = 0.003), were significantly improved in experimental group. …”
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Effectiveness of a Family-Based Self-Management Intervention for Type 2 Diabetes Patients Receiving Family Doctor Contract Services: A Community-Based Randomized Controlled Trial by Lan Zhu, Jing Wang, Zhigang Pan, Wei Zhang, Jing Tang, Hua Yan, Fulai Shen, Yi Shen

“…The intervention group demonstrated significant improvements in family support, family function, diabetes knowledge, and self-efficacy. …”
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Efficacy and Safety of Initial Combination Treatment of an Alpha Blocker with an Anticholinergic Medication in Benign Prostatic Hyperplasia Patients with Lower Urinary Tract Sympto... by Hyun Jung Kim, Hwa Yeon Sun, Hoon Choi, Jae Young Park, Jae Hyun Bae, Seung Whan Doo, Won Jae Yang, Yun Seob Song, Young Myoung Ko, Jae Heon Kim

“…<h4>Methods</h4>We conducted a meta-analysis of improvement in LUTS using International Prostate Symptom Score (IPSS), maximal urinary flow rate (Qmax), post-voided residual volume (PVR), and quality of life (QoL).…”
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Chronic Progressive External Ophthalmoplegia (CPEO): Rehabilitation utilizing scleral contact lenses by Nir Erdinest, Nadav Shemesh, Naomi London, David Landau, Itay Lavy

“…Diagnosed with blepharoptosis, myogenic ptosis, dry eye syndrome, dermatochalasis, and lagophthalmos, she showed no improvement post-prolene frontalis suspension surgery. …”
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Effect of abdominal acupuncture combined with routine rehabilitation training on shoulder-hand syndrome after stroke: A randomized controlled trial by Jie Zhan, Yirang Ai, Lechang Zhan, Ruihuan Pan, Yiqiao Wang, Cong Dong, Qiuchun Wang, Hongxia Chen, Liming Lu, Mei Li

“…Conclusions: BAA combined with RT is superior to RT alone in improving shoulder pain, swelling, and ADL in post-stroke SHS patients. …”
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Delirium following mechanical thrombectomy for ischemic stroke – individuals at risk, imaging biomarkers and prognosis by Marianne Hahn, Lavinia Brockstedt, Sonja Gröschel, Katharina Geschke, Nils F. Grauhan, Marc A. Brockmann, Ahmed E. Othman, Klaus Gröschel, Timo Uphaus

“…AimPost-stroke-delirium has been linked to worse outcome in patients with acute cerebrovascular disease; identification of individuals at risk may prevent delirium and thereby improve outcome. …”
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Ketogenic metabolic therapy in the remission of chronic major depressive disorder: a retrospective case study by Nicole Laurent, Erin L. Bellamy, Donika Hristova, Ally Houston

“…Outcomes were assessed using validated tools for symptom severity, including PHQ-9 for depression and GAD-7 for anxiety, at baseline, 2 months, and 4 months post-intervention. Qualitative data on patient experiences and functional improvements were also collected.ResultsThe patient achieved remission of MDD within 8 weeks of initiating KMT, with PHQ-9 scores decreasing from 25 (severe depression) at baseline to 0 at 2- and 4-month assessments. …”
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Intensive Speech Therapy for Hypokinetic Dysarthria in Parkinson’s Disease: Targeting the Five Subsystems of Speech Production with Clinical and Instrumental Evaluation by Annalisa Gison, Marco Ruggiero, Davide Tufarelli, Stefania Proietti, Daniela Moscariello, Marianna Valente

“…<i>Conclusions</i>: Significant improvements were observed in tongue and lip strength, phonatory duration, intensity, and vocal quality between pre- (T1) and post-treatment (T2). …”
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Probiotics mitigate stress and inflammation in malnourished adults via gut microbiota modulation: a randomized controlled trial by Maryam Ahmadi-Khorram, Maryam Ahmadi-Khorram, Alireza Hatami, Alireza Hatami, Parastoo Asghari, Parastoo Asghari, Ali Jafarzadeh Esfehani, Asma Afshari, Fateme Javdan, Fateme Javdan, Mohsen Nematy, Mohsen Nematy

“…ObjectiveMalnutrition negatively affects mental health by altering neurotransmitter function and increasing stress responses. The gut-brain axis is pivotal in this process, and probiotics may mitigate stress. …”
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Feasibility and acceptability of a single-session perioperative acceptance and commitment therapy workshop for preventing chronic postsurgical pain: a single-arm, non-randomized pi... by Jolin B. Yamin, Jolin B. Yamin, Jenna M. Wilson, Jenna M. Wilson, Bethany D. Pester, Caroline Allen, JiHee Yoon, Marise C. Cornelius, Marise C. Cornelius, Diya Dharmendran, Diya Dharmendran, Kylie Steinhilber, Kylie Steinhilber, Madelyn Crago, Savannah Kazemipour, Angelina Franqueiro, Delia Fentazi, Kristin L. Schreiber, Kristin L. Schreiber, Kevin E. Vowles, Robert R. Edwards, Robert R. Edwards, Robert N. Jamison, Robert N. Jamison, Samantha M. Meints, Samantha M. Meints

“…CEQ and THQ scores indicated high credibility and helpfulness immediately after the intervention and at 1-month post-surgery. Exploratory analyses examining health outcome changes following ACT during the post-surgery period revealed that pain severity and interference, depression and anxiety all decreased over time.DiscussionThese findings suggest that a single-session ACT intervention is feasible and acceptable for patients undergoing SS and may enhance both pain-related functioning and improve psychological outcomes following surgery. …”
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Zingerone Attenuates Cadmium-Induced Neuroinflammation, Oxidative Stress and Cognitive Deficit on the Prefrontal Cortex of Adult Wistar Rats by Oviosun A, Oviosun EC, Nto NJ, Memudu AE, Anyanwu EG

“…Zingerone considerably improved cognitive function, as seen by significant improvements in the discrimination index and novel object recognition time. …”
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Comparison of Spencer muscle energy technique and conventional physiotherapy on pain and disability in shoulder adhesive capsulitis: a quasi-experimental study by Aisha Amin, Ramsha Malik, Sajjan Iqbal Memon, Zainab Zafar Awan, Faiza Almas, Rabia Talab Hussain, Qurat-ul-ain Zahra

“…The present study aims to evaluate the effectiveness of the Spencer muscle energy technique (SMET) in reducing pain and improving functional disability in patients diagnosed with adhesive capsulitis. …”
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Effect of cervical traction on cervicogenic headache in patients with cervical radiculopathy: a preliminary randomized controlled trial by Anis Jellad, Amine Kalai, Amr Chaabeni, Cyrine Ben Nasrallah, Atef Ben Nsir, Mahbouba Jguirim, Asma Belguith Sriha, Zohra Ben Salah Frih, Mohamed Hedi Bedoui

“…Both groups C and B showed a significant improvement in radicular pain compared to group A at one month follow-up (p = 0.05).The improvement in group C was significantly better in terms of function (p = 0.049) and anxiety (p = 0.011) at three months and quality of life at six months (Psychological p = 0.046 and Environment p = 0.006). …”
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Donor Lungs’ Procurement Implementation with Ex Vivo Lung Perfusion in a Low-Volume Lung Transplant Center by Matteo Petroncini, Elena Salvaterra, Leonardo Valentini, Silvia Bonucchi, Niccolò Daddi, Saverio Pastore, Pietro Bertoglio, Piergiorgio Solli, Filippo Antonacci

“…Despite an improvement in lung function, 47% of donor lungs were rejected after EVLP. …”
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The effects of dance intervention on clinical symptoms and cognitive deficits in hospitalized patients with chronic schizophrenia: a randomized controlled trial by Gujing Li, Hui He, Kexin Gao, Yuanyuan Yu, Yayun Liu, Tianhuan Li, Ping Xi, Frank Pollick, Jing Lu, Lixue Yin, Dezhong Yao, Mingjun Duan, Li Mi, Cheng Luo

“…Conclusion While both interventions resulted in improvements in clinical symptoms and cognitive function, the dance intervention specifically enhanced attention and verbal memory. …”
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Liver‐directed gene therapy for ornithine aminotransferase deficiency by Iolanda Boffa, Elena Polishchuk, Lucia De Stefano, Fabio Dell'Aquila, Edoardo Nusco, Elena Marrocco, Matteo Audano, Silvia Pedretti, Marianna Caterino, Ilaria Bellezza, Margherita Ruoppolo, Nico Mitro, Barbara Cellini, Alberto Auricchio, Nicola Brunetti‐Pierri

“…AAV‐injected mice showed improved electroretinogram response and partial restoration of retinal structure up to one‐year post‐injection. …”
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Extensive locally invasive nasopharyngeal carcinoma involving 10 cranial nerves palsies: an interesting case report by Abdulrazaq Albilali, Naif H. Alotaibi, Abdulaziz Alfadley, Khalid M. Alqarni, Abdullah Alhajlah

“…Partial recovery of cranial nerve function following chemoradiotherapy emphasize the potential for neurological improvement in advanced NPC with comprehensive, multidisciplinary care.…”
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Prevention and treatment of social anxiety disorder in adolescents: mixed method randomised controlled trial of the guided online intervention SOPHIE by Noemi Walder, Thomas Berger, Dominique Hürzeler, Emily McDougal, Julian Edbrook-Childs, Stefanie J. Schmidt

“…Subgroup analyses by diagnostic condition showed a significant between-group effect at follow-up in the subclinical social anxiety (d = 1.53, 95%CI [1.74;0.41]) but not in the SAD condition. Social functioning significantly improved at post-intervention and follow-up, with medium to large effects (post: d=-0.73, 95%CI [-1.08; -0.37]; follow-up: d=-0.32, 95%CI [-0.66; 0.02]). …”
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