IDE-SVM algorithm and it's usage in physical layer security method for IoT by WANG Qiang, ZHU Chenming, PAN Su, QIN Yuxi

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Patient-Reported Continued Benefits in Patients Treated with Pexidartinib for Tenosynovial Giant Cell Tumor Based on a Real-World Study in the United States by Margaret Wooddell PhD, MBA, Dong Dai PhD, Feng Lin PhD, Irene Pan MS, Klaus Freivogel PhD, Xin Ye PhD, Kristen Tecson PhD, William D. Tap MD

“…Since the start of the study, the majority (85.7%) of respondents experienced improved overall symptoms. Conclusion: In this study, most TGCT patients reported symptom improvement in physical function, stiffness and pain during pexidartinib treatment. …”
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An Analysis of the Outcomes and Complications of Ultrasound Guided Corticosteroid Injection on Tendinopathy in the Foot and Ankle by Benjamin Jacques MS, Miraj N. Desai MD, Chase Gauthier MD, Tyler Gonzalez MD, MBA, J. Benjamin Jackson MBA. MD

“…Overall, patients who received a corticosteroid injection had significant improvements in their pain interference (63.3 vs 58.7, p< 0.001), physical function (38.9 vs 41.3, p=0.032), and mobility (37 vs 39.7, p=0.006) scores. …”
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Implementing psychosocial guidelines into specialized spinal cord injury rehabilitation services to strengthen person-centred health care: protocol for a mixed methods study by Candice McBain, Candice McBain, Anne Marie Sarandrea, Anne Marie Sarandrea, Anne Marie Sarandrea, Ilaria Pozzato, Ilaria Pozzato, Mohit Arora, Mohit Arora, Daniel Myles, Daniel Myles, John Bourke, John Bourke, Yvonne Tran, Ian D. Cameron, Ian D. Cameron, James W. Middleton, James W. Middleton, James W. Middleton, Ashley Craig, Ashley Craig

“…BackgroundSpinal cord injury (SCI) is a severe neurological disorder resulting in loss of movement and altered sensation with lifelong impacts on health, function, and social integration. Multidisciplinary SCI rehabilitation primarily focuses on enhancing function and independence while simultaneously managing secondary health conditions and providing psychosocial support. …”
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Comparative efficacy of Pirfenidone and Meloxicam on early radiotherapy-induced anal sphincter dysfunction in rats by Dragoș Viorel Scripcariu, Cezar Cătălin Caratașu, Mitică Ciorpac, Teodora Alexa-Stratulat, Andrei Szilagyi, Cristian Răzvan Buga, Bogdan Ionuţ Dobrovăț, Bogdan Ionuţ Dobrovăț, Lucian Eva, Andrei Daniel Timofte, Ludmila Lozneanu, Irina-Draga Căruntu, Radu Iliescu, Bogdan Ionel Tamba

“…The groups treated with Pirfenidone, alone and in combination with Meloxicam exhibited significant improvements in sphincter contractility and showed a notable mitigation in external anal sphincter thickness, concomitant with reduction in collagen deposition and preservation of muscular tissue, compared with untreated irradiated animals.ConclusionThis study demonstrates that Pirfenidone, either as monotherapy or in combination with Meloxicam, mitigates radiation-induced fibrotic remodeling and preserves anal sphincter function. …”
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Long‐term immune changes after COVID‐19 and the effect of BCG vaccination and latent infections on disease severity by Kamila Bendíčková, Ioanna Papatheodorou, Gabriela Blažková, Martin Helán, Michaela Haláková, Petr Bednář, Erin Spearing, Lucie Obermannová, Julie Štíchová, Monika Dvořáková Heroldová, Tomáš Tomáš, Roman Panovský, Vladimír Šrámek, Marco De Zuani, Marcela Vlková, Daniel Růžek, Marcela Hortová‐Kohoutková, Jan Frič

“…Conclusion These findings highlight the long‐term alterations of immune cells in post‐COVID‐19 patients, emphasising the substantial impact of COVID‐19 on immune function.…”
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A Case Report: Electrotonic Modulation‐Related T‐Wave Over‐Sensing After Left Bundle Branch Pacing by Linlin Li, Manxin Lin, Jincun Guo, Qiang Li, Fanqi Meng, Xinyi Huang, Simei Chen, Binni Cai

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Biophysical and nutritional combination treatment for myosteatosis in patients with sarcopenia: a study protocol for single-blinded randomised controlled trial by Maoyi Tian, Ling Qin, Simon Kwoon Ho Chow, Wing Hoi Cheung, A A Welch, Can Cui, Parco M Siu, Meng Chen Michelle Li, Yu Kin Cheng, Ronald Man Yeung Wong, Timothy CY Kwok, Minghui Yang, Clinton Rubin, Sheung Wai Law

“…Previous studies showed that β-hydroxy β-methylbutyrate (HMB) supplement and vibration treatment (VT) enhanced muscle quality, while the coapplication of the two interventions had further improved muscle mass and function in sarcopenic mice model. …”
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Multimodal Non-Pharmacological Interventions for Fibromyalgia: Targeting Emotional and Cognitive Symptoms by Anca Maria Amzolini, Daniela Matei, Magdalena Rodica Traistaru, Ana Maria Bumbea, Miruna Andreiana Matei, Maria Teodora Amzolini, Anda Patru, Mihai Cealicu, Constantin Munteanu, Simona Patru

“…Stretching exercises contributed to sustained symptom relief, CBT was effective for emotional regulation, and OT improved cognitive function. Clinicians should consider patient-specific needs when designing rehabilitation strategies. …”
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Aging Population and the Changing Paradigm of Hip Fracture Management by Amit Sharma

“…Centralized hip fracture wards with standardized protocols have better outcomes than fragmented care models.4 A key change in hip fracture management is the emphasis on early surgery, ideally within 36 hours of admission, which has been shown to decrease mortality and improve functional outcomes. Delays should be avoided, even for chronic conditions that cannot be immediately addressed. …”
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Co-modulation of a circular form of PCDH11Y during neuroendocrine differentiation of prostate cancer by Giovanni Pecoraro, Ilaria Leone, Silvia Nuzzo, Santiago Negueruela, Giovanni Smaldone, Lorena Buono

“…To achieve that, we applied CirComPara2 pipeline to publicly available datasets to identify the differently expressed circRNAs in the LNCaP cell lines pre- and post-transdifferentiation. After that, validation and functional analysis by RNA-interference was applied to a selected circRNA to explore its role during NED. …”
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Prevalence and therapeutic outcomes of intraoperative MCL injury in subjects undergoing total knee arthroplasty by Sepehr Shirouei, Mehdi Karimi, Gholamreza Ghorbani Amjad, Morteza Majidi, Niyousha Shirsalimi, Abbas Moradi

“…Patients showed significant improvements in pain and knee function, with no complications or instability at one-year follow-up, indicating that MCL injuries do not compromise TKA success.…”
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Comparison of different electrotherapy methods and exercise therapy in shoulder impingement syndrome: A prospective randomized controlled trial by Sevtap Gunay Ucurum, Derya Ozer Kaya, Yasemin Kayali, Ayhan Askin, Mustafa Agah Tekindal

“…Conclusion: Application of ultrasound, interferential current and TENS in addition to exercise therapy in shoulder impingement syndrome treatment had similar improvements in terms of pain, function and physical component of quality of life. …”
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A 24‐week double‐blind placebo‐controlled study of the efficacy and safety of the AMPA modulator S47445 in patients with mild to moderate Alzheimer's disease and depressive symptom... by Katy Bernard, Sylvie Gouttefangeas, Sylvie Bretin, Stéphanie Galtier, Philippe Robert, Vjera Holthoff‐Detto, Jeffrey Cummings, Maria Pueyo

“…An improvement on neuropsychiatric symptoms assessed by NPI was evidenced at the lower dose 5 mg/d (Δ ‐2.55, P = .023, post hoc analysis) compared to placebo. …”
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The Nebraska Nomogram for Autograft Planning (NNAP) a surgical planning tool for ipsilateral rotational autokeratoplasty by Collin Asheim, Ashok Puri, Helen Song, Brian Armstrong, Sam Navon, Ronald Krueger

“…A patient undergoing IRA with this software achieved successful graft placement, improved visual function, and no post-operative complication or rejection. …”
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Docosahexaenoic Acid and Nervonic Acid Synergically Enhance Cognitive Memory in Normal Mice via Brain Fatty Acids Remodeling by Hai‐Yan Ou, Lei Feng, Rui‐Ye Chen, Hui‐Yun Lu, Shuang Cai, Zhi‐You Yang

“…Preclinical and clinical studies suggest the effects of DHA or NA supplementation on memory improvement in aging and Alzheimer's disease models. …”
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Is a multidimensional robotic rehabilitation approach feasible in Guillain-Barrè syndrome? Report from a clinical case by Caterina Tramonti, Benedetta Gnetti, Paola Gemignani, Stefania Callegari, Marco Germanotta, Francesca Cecchi, Irene Giovanna Aprile, Pietro Balbi

“…Despite the residual global impairment, this treatment, specifically tailored on patient’s skills and progress, promoted improvements in functional abilities such as motricity, trunk control, and activities of daily living. …”
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Extracting Realistic Pedestrian, Cycling, and Driving Street Networks from OpenStreetMap by J. P. Duque, M. A. Brovelli

“…The methodology also offers an assessment functionality to identify potential inconsistencies in OSM extracted networks, providing support for mapping campaigns seeking to improve its quality. …”
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Evobrutinib mitigates neuroinflammation after ischemic stroke by targeting M1 microglial polarization via the TLR4/Myd88/NF-κB pathway by Yixiang Jiang, Ning Wang, Jingyi Liu, Jiayi Li, Lulu Chang, Changxin Yang, Zhengyi Chen, Wei Huang, Jing Wang, Xiujuan Lang, Xijun Liu, Yumei Liu, Bo Sun, Hulun Li

“…Graphical abstract Evobrutinib treatment improves neurological function of mice with cerebral ischemia, and alleviates neuroinflammation by inhibiting M1 microglia polarization through TLR4/Myd88/NF-κB pathway.…”
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Stabilization of influenza vaccine enhances protection by microneedle delivery in the mouse skin. by Fu-Shi Quan, Yeu-Chun Kim, Dae-Goon Yoo, Richard W Compans, Mark R Prausnitz, Sang-Moo Kang

“…Importantly, a single microneedle-based vaccination using stabilized influenza vaccine was found to be superior to intramuscular immunization in controlling virus replication as well as in inducing rapid recall immune responses post challenge.<h4>Conclusions/significance</h4>The functional integrity of hemagglutinin is associated with inducing improved protective immunity against influenza. …”
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