Unraveling the role of long non-coding RNAs in therapeutic resistance in acute myeloid leukemia: New prospects & challenges by Siddhant Sharma

“…In recent years, long non-coding RNAs (lncRNAs) have increasingly become important prognostic and therapeutic hotspots, due to their contributions to dysregulating many functional epigenetic, transcriptional, and post-translational mechanisms leading to alterations in cell expressions, resulting in increased chemoresistance and reduced apoptosis in leukemic cells. …”
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Drawing to remember: external support of older adults' eyewitness performance. by Coral J Dando

“…Although healthy aging is accompanied by a general decline in memory functioning, environmental support at retrieval can improve older adults' (+65 years) episodic remembering. …”
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Attachment and trauma-informed programme to support forcibly displaced parents of youth in Sweden: feasibility and preliminary outcomes of the eConnect Online programme by Raziye Salari, Fatumo Osman, Anna Kristen, Marlene Moretti

“…Youth mental health problems (η2=0.29) and family functioning significantly improved (η2=0.18) over the course of the programme. …”
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Symptomatic and cognitive effects of D-amino acid oxidase inhibitors in patients with schizophrenia: a meta-analysis of double-blind randomized controlled trials by Chun-Hung Chang, Yu-Der Hsia, Wen-Chun Liu, Jia-Hau Lee, Chieh-Hsin Lin, Hsien-Yuan Lane

“…Clinical and cognitive improvements were compared between baseline and post-DAOI treatment using standardized mean differences (SMDs) with 95% confidence intervals (CIs). …”
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Fractional CO𝟐 laser therapy for vulvar lichen sclerosus in adults by Xiaojuan Wang, Yisong Chen, Luwen Wang, Zhong Lin, Keqin Hua

“…Background: The CO2 laser has been used to treat vulvar lichen sclerosus (VLS) with a significant reduction in symptoms, and there is a paucity data on the efficacy, sexual function, and quality of life (QOL) improved. This study was to evaluate the efficacy of fractional CO2 laser for VLS and assess sexual function and QOL from multi-centers. …”
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Physical activity interventions in adult kidney transplant recipients: an updated systematic review and meta-analysis of randomized controlled trials by Roseanne E. Billany, Nicolette C. Bishop, Ellen M. Castle, Matthew P. M. Graham-Brown, Sharlene A. Greenwood, Courtney J. Lightfoot, Thomas J. Wilkinson

“…Most studies used a mixture of aerobic and resistance training but reporting and intervention content was highly varied. Significant improvements were observed in CRF (V̇O2peak; +3.87 mL/kg/min, p = .0004), physical function (sit-to-stand-60; +7.72 repetitions, p = .0001), and high-density lipoprotein (HDL; +0.13 mmol/L, p = .02). …”
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Implementing My PreHab Program: How digital technology helped to bridge the hospital-community gap and streamline hospital processes by Eleanor R Bills, Anastasia D Westin, Jane M Andrews

“…These complications are associated with worse psychosocial outcomes, delayed function recovery, financial costs and reduced patient flow. …”
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Telerehabilitation for Exercise Training in Pregnancy by Esra Uzelpasaci, Levent Ozcakar, Serap Ozgul, Ozgur Ozyuncu, Mehmet Sinan Beksac, Turkan Akbayrak

“…The evaluations were repeated after the exercise program and the Wilcoxon test was used to compare the pre- vs. post-treatment results. RESULTS: Physical function, physical and emotional role difficulty, pain subscale of SF-36, low back pain severity, walking distance in the 6-minute walking test, Oswestry Low Back Pain Disability Questionnaire scores seemed to have improved after the exercise program. …”
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Rehabilitation of the Upper Extremity after Stroke: A Case Series Evaluating REO Therapy and an Auditory Sensor Feedback for Trunk Control by G. Thielman, P. Bonsall

“…With both interventions, clinically relevant improvements were found for measures of body function and structure, as well as for activity, for two participants. …”
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In cats with cranial cruciate rupture are better long-term outcomes achieved by surgical or conservative management? by Philip Montgomery

“…Question In cats diagnosed with isolated rupture of the cranial cruciate ligament, does surgical intervention result in improved long-term function, when compared with conservative management?   …”
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Pro: Clinical remission in asthma – implications for asthma management by Stefania Principe, Nizar N. Jarjour

“…Real-world studies and post hoc analyses of clinical trials emphasise the potential of biologics in achieving clinical remission in a significant proportion of patients. …”
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Breaking the Mold: Bilateral Lateral End Clavicle Fractures Treated with Dog Bone Button Fixation - A Rare Case by Nitesh Kumar Rathi, D Raja Sujith Kumar, J Benjamin Vinodh, Naveen Sathyaseelan, Arun Vignesh

“…Surgical fixation using the dog bone button technique was performed bilaterally. Post-operative rehabilitation involved early mobilization, and at 6 weeks, the patient demonstrated significant functional improvement, confirmed by disabilities of the arm, shoulder and hand and Oxford shoulder scores. …”
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Mobilization with movement plus exercise versus exercise alone for patients with central sensitization associated with chronic subacromial pain syndrome: a sham-controlled randomiz... by Volkan Deniz, Bayram Kelle

“…Results At baseline, there were no significant differences in age, gender, or clinical characteristics among the groups. At the post-intervention stage, MWM combined with exercise did not result in superior improvements in CSI scores, local-widespread PPTs, or functional disability compared to sham-MWM or exercise alone (p > 0.05 for all). …”
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Study of the Repair Action and Mechanisms of a Moisturizing Cream on an SLS-Damaged Skin Model Using Two-Photon Microscopy by Yixin Shen, Ying Ye, Lina Wang, Huiping Hu, Caixia Wang, Yuxuan Wu, Dingqiao Lin, Jiaqi Shen, Hong Zhang, Yanan Li, Peiwen Sun

“…Notably, the cream facilitated a significant increase in epidermal thickness and improved the dermal–epidermal junction index (DEJI), as observed through TPM, indicating profound skin repair and enhanced barrier functionality. …”
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Potential Role of Exosomes in Mending a Broken Heart: Nanoshuttles Propelling Future Clinical Therapeutics Forward by Julie A. Dougherty, Muhamad Mergaye, Naresh Kumar, Chun-An Chen, Mark G. Angelos, Mahmood Khan

“…Stem cell transplantation therapy is a promising adjunct for regenerating damaged heart tissue; however, only modest improvements in cardiac function have been observed due to poor survival of transplanted cells in the ischemic heart. …”
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Guidelines for standard operation of imaging modalities in orbital diseases (2024) by Yi Shao, Jian-Min Ma, Xiao-Ming Huang, Expert Workgroup of Guidelines for the use of imaging equipment in orbital diseases (2024), Ophthalmic Imaging and Intelligent Medicine Branch Chinese Medicine Education Association, Ocular Oncology Committee of the Ophthalmology Branch of the Chinese Medical Doctor Association, Ophthalmology Committee of International Association of Translational Medicine, Chinese Ophthalmic Imaging Study Groups

“…As such, the vital instruments for diagnosing and evaluating orbital illnesses have become ophthalmic imaging modalities, including ocular ultrasonography (B-scan), computed tomography (CT), and magnetic resonance imaging (MRI). One way to improve the precision and promptness of diagnosing orbital diseases is to standardize the functioning of widely used imaging equipment and define the radiological features of orbital abnormalities. …”
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Therapeutic Potential of Kelp Fucoidan in Rebiosis of Gut Microflora and Immune Homeostasis in Cyclophosphamide-Induced Immunosuppressed Mice by Yaqing Liu, Ruining Kang, Yanfei Zhao, Heng Zhang, Qingfeng Rong, Shaoxuan Yu, Yaoguang Chang, Zhengpeng Wei, Lanlan Zhu

“…Furthermore, the levels of acetic, propionic, and butyric acids in the colonic contents of the kelp fucoidan group significantly improved (<i>p</i> < 0.01). This research demonstrates that kelp fucoidan enhances immune function in immunosuppressed mice by modulating gut microbiota balance and promoting short-chain fatty acid production.…”
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Effects of Esketamine Combined With Remimazolam Tosylate on Hemodynamics During Cardiovascular Anesthesia by Lei Xi, Hui Liu, XiaoJuan Tang, ZhenZhen Jiang

“…The combination of esketamine and remimazolam tosylate offers hemodynamic stability, enhances cerebral oxygen metabolism, improves cognitive function, and reduces myocardial injury in patients undergoing heart valve replacement surgery. …”
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The Psychological and Physical Benefits of Progressive Muscle Relaxation in Chronic Respiratory Diseases: A Systematic Review by Adelina Maritescu, Alexandru Florian Crisan, Camelia Corina Pescaru, Cristian Oancea, Daniela Iacob

“…Some also reported improvements in dyspnea and mild pulmonary function tests, but these were more variable. …”
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Neocondylar Formation with Vascularized Fibular Free Flap: A Report of Three Rare Cases and Review of Literature by Mark Lim, Ignacio A. Velasco Martinez, Tina Woods, Ben McIntyre, Ibrahim Sevki Bayrakdar, Sevda Kurt-Bayrakdar, Rohan Jagtap

“…Neocondylar formation after a vascularized free flap reconstruction can improve anatomical functions such as mastication and decrease post-operative complications. …”
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