Cellular dynamics of myogenic cell migration: molecular mechanisms and implications for skeletal muscle cell therapies by SungWoo Choi, Giulia Ferrari, Francesco Saverio Tedesco

“…Here, we review mechanisms of myogenic stem/progenitor cell migration during skeletal muscle development and post‐natal regeneration. Furthermore, strategies utilised to improve migratory capacity of myogenic cells are examined in order to identify potential treatments that may be applied to future transplantation protocols.…”
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Protocol for a Field Trial of a Hearing and Vision Support Intervention for People Living in Long‐Term Care in Australia by Carly Meyer, Najwan El‐Saifi, Naomi Rose, Kasia Bail, Colette Browning, Dayna Cenin, Antonio Ahumada‐Canale, Megan Campbell, Tim England, Melanie Ferguson, Yuanyuan Gu, Reema Harrison, Chyrisse Heine, Lisa Keay, Sheela Kumaran, Iracema Leroi, Gerald Liew, Angelita Martini, Ralph Martins, John Newall, Smriti Raichand, Emma Scanlan, Hamid R. Sohrabi, Melinda Toomey, Johanna Westbrook, Piers Dawes

“…This protocol involves a systematic evaluation of the effectiveness and implementation challenges of a pragmatic SSI to optimise hearing and vision function and improve the quality of life for long‐term care residents and their caregivers.…”
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Natural killer cells adopt an activated and decidual-like phenotype after autologous hematopoietic stem cell transplantation in children with cancer by Gabirel Astarloa-Pando, Diego Polanco-Alonso, Víctor Sandá, Ane Orrantia, Ainhoa Amarilla-Irusta, Silvia Pérez-Fernández, Raquel Pérez-Garay, Arrate Sevilla, Ainara Lopez-Pardo, Aritz Tijero, José J. Úriz, Mercedes Rey, Itziar Astigarraga, Bárbara Manzanares-Martin, Aitor Zarandona-Garai, Naiara G. Bediaga, Laura Amo, Olatz Zenarruzabeitia, Francisco Borrego

“…Investigating NK cell recovery could improve understanding of post-autoHSCT immune reconstitution and optimize clinical outcomes. …”
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Therapeutic Efficacy of Alpha-Lipoic Acid against Acute Myocardial Infarction and Chronic Left Ventricular Remodeling in Mice by Zequan Yang, Yikui Tian, Stuart S. Berr, Brent A. French

“…Treatment with ALA (75 mg/kg·d) or H2O was initiated 1 day post-AMI and continued until study’s end. Both LVESV and LVEF in ALA-treated mice were significantly improved over control when assessed 28 or 56 days post-AMI. …”
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Contribution of brain pericytes to neuroinflammation following repetitive head trauma by Arianna Cembran, Maxwell Eisenbaum, Daniel Paris, Michael Mullan, Fiona Crawford, Scott Ferguson, Corbin Bachmeier

“…As the platelet-derived growth factor (PDGF) pathway is critical to pericyte function, we also assessed the effect of PDGF-BB stimulation on the inflammatory response in pericytes. …”
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Protocol Biopsies in Kidney Transplant Recipients: Current Practice After Much Discussion by Christina Lazarou, Eleni Moysidou, Michalis Christodoulou, Stamatia Stai, Georgios Lioulios, Efstratios Kasimatis, Asimina Fylaktou, Maria Stangou

“…Early detection facilitates timely therapeutic interventions, including immunosuppressive regimen adjustments, which are pivotal in preserving graft function and improving long-term outcomes. While the optimal timing and frequency of protocol biopsies vary, early post-transplant biopsies within the first year are widely advocated. …”
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Treatment-related toxicity, utility and patient-reported outcomes of head and neck cancer patients treated with proton therapy: A longitudinal study by Yi Hsuan Chen, Michiel Kroesen, Mischa Hoogeman, Matthijs Versteegh, Carin Uyl-de Groot, Hedwig M. Blommestein

“…Most of the functions recovered within six months and improved beyond baseline. …”
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Examining acquired brain injury-associated symptoms and fluid-based biomarkers in females surviving intimate partner violence: An observational pilot study protocol by Michelle Patch, Allison Jacobi-Dorbeck, Tamar Rodney, Gabor Kelen, Jacquelyn C Campbell, Leah H Rubin, Chelsea Wagner, Nancy Perrin, Jessica Gill

“…Future research should focus on translating these findings into evidence-based practice to improve outcomes for women with ABI, particularly those resulting from IPV.…”
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Application of different approaches in interventional thrombolysis of deep vein thrombosis of lower extremities by YUAN Xiaopu, YANG Lili, WU Hongfang

“…Conclusion：Both the popliteal vein approach and the infrapatellar vein approach for interventional thrombolysis effectively clear thrombus, improve coagulation function, and reduce limb swelling in DVT patients, with good long-term effects and safety. …”
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Hesperetin attenuates ischemia/reperfusion-induced acute kidney injury by regulating ferroptosis in mice by Xiaoyu Xie, Chen Guan, Ningxin Zhang, Chenyu Li, Zengying Liu, Chengyu Yang, Liting Wang, Yan Xu

“…Bioinformatics and molecular docking confirmed hesperetin’s binding affinity with Src, and immunohistochemistry showed altered phosphorylated Src expression in kidneys post-intervention.Results Hesperetin effectively improved renal function and alleviated renal injury. …”
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Tibial tubercle osteotomy for the exposure of complex primary and revision Total Knee Arthroplasty- our 21 years of experience by Ameya Katariya, P. Suryanarayan, Vijay Bose, P.S. Ashok Kumar, Kalaivanan Kanniyan, Shantanu Patil

“…However, good surgical technique and titrated rehabilitation program remain the key to achieve good post-operative function and minimise complications.…”
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Clinical Utility of Speckle Tracking Echocardiography in Heart Transplantation by Qin Shuxuan, He Qing, Wu Zhenni, Lin Yixia, Ji Mengmeng, Zhang Li, Xie Mingxing, Li Yuman

“…Speckle tracking echocardiography (STE), a key non-invasive diagnostic method, has become indispensable for providing an in-depth analysis of myocardial mechanics and function. This review focuses on the clinical utility of STE in both pre- and post-transplant settings. …”
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EART HEMODYNAMICS IN EARLY PERIOD OF ACUTE ST ELEVATION ANTERIOR MYOCARDIAL INFARCTION BY 2D SPECKLE TRACKING ECHOCARDIOGRAPHY by M. A. Kercheva, T. R. Ryabova, V. V. Ryabov, R. S. Karpov

“…Changes in biomechanics of the heart by 2D speckle tracking echocardiography in patients with the use of modern and on-time pharmacoinvasive strategy at early post-infarction period represented the restoring of cardiac function, while standard parameters (ESV, EDV, EF LV) did not show dynamics. …”
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Ureter‐ileum‐interposition: Combined experience from two high‐volume centres by Maksym Pikul, David Pfister, Constantin Rieger, Christian Bach, Oleg Voylenko, Oleksandr Stakhovskyi, Sofiya Semko, Iurii Vitruk, Oleksii Kononenko, Eduard Stakhovsky, Axel Heidenreich

“…Metabolic acidosis was clinically significant in 7.5% of cases. A slight improvement in renal function was observed during the first year post‐surgery (average postoperative eGFR = 76 ± 22 ml/min; Mann–Witney U test, p = 0,0198). …”
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ADMINISTRATION OF LACTULOSE IN COMPLEX PEHABILITATION TREATMENT AFTER RADICAL AND RECONSTRUCTIVE RESTORATIVE SURGERY OF BOWELS IN CHILDREN by I.V. Kirgizov, I.A. Shishkin, A.A. Gusev, P.V. Ivanov

“…It was shown, that prolonged (1 month and more) administration of lactulose (Duphalac) results in improvement of motor and evacuation function of bowel, and decreases «sensor inability» of reduced parts of bowel. …”
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Global Longitudinal Strain: A Novel Predictor of Postoperative Outcomes in Children Undergoing Rheumatic Valve Surgery by Sowmya Kasturi, Srinath Reddy Narahari, Anand Kumar Gowdhaman, Dipesh Trivedi, Ganapathy Subramaniam, Abhinav Singh Chauhan

“…The immediate outcomes studied were the duration of intensive care unit (ICU) and hospital stay, average vasoactive inotrope score (VIS), duration of inotropes and medium term outcomes were LV function and GLS at one year. Results: A peak GLS value of ≤−15% was associated with longer post operative ventilation and inotrope requirement. …”
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Analyses of the redistribution of work following cardiac resynchronisation therapy in a patient specific model. by Steven Alexander Niederer, Pablo Lamata, Gernot Plank, Phani Chinchapatnam, Matt Ginks, Kawal Rhode, Christopher Aldo Rinaldi, Reza Razavi, Nicolas Peter Smith

“…Simulations of electromechanical cardiac function in the model estimate the regional stress, strain and work pre- and post-CRT. …”
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Comparison of outcomes between 2 week versus 4 week stenting in pediatric pyeloplasty—A single centre observational study by Santosh Dey, Venkat Shankar Raman, Tarun Peela, Karunesh Chand, Naveen Chandra

“…Forty-three underwent late stent removal (Group 1) and 29 underwent early stent removal (Group 2). Pre-operative and post-operative follow-up data were compared to see the effect of early stent removal on the postoperative drainage pattern at 6 months after surgery and improvement in split function of affected kidney. …”
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Evaluating a Web-Based Application to Facilitate Family-School-Health Care Collaboration for Children With Neurodevelopmental Disorders in Inclusive Settings: Protocol for a Nonran... by Eric Meyer, Hélène Sauzéon, Isabeau Saint-Supery, Cecile Mazon

“…The control group is asked to function as usual to support the child in inclusive settings. …”
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Muscle growth and anabolism in intensive care survivors (GAINS 2.0): Protocol for a multi-centre randomised; placebo controlled clinical trial of nandrolone in deconditioned adults... by Matthew Anstey, Ed Litton, Maryam Habibi, Lisa Van der Lee, Robert Palmer, Natalie Tran, Bianca Mammana, Stacey Scheepers, Annamaria Palermo, Xavier Fiorilla, Bhaumik Mevavala, Adrian Regli, Angela Jacques, Bradley Wibrow

“…We hypothesize nandrolone will improve muscle strength and physical functioning at hospital discharge and at follow-up. …”
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