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Microbiota as diagnostic biomarkers: advancing early cancer detection and personalized therapeutic approaches through microbiome profiling
Published 2025-05-01“…The important function of microbiota as therapeutic modulators and diagnostic biomarkers in cancer has been shown by recent developments in microbiome research. …”
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Hierarchical multi step Gray Wolf optimization algorithm for energy systems optimization
Published 2025-03-01Get full text
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Advancements in Hyperspectral Imaging and Computer-Aided Diagnostic Methods for the Enhanced Detection and Diagnosis of Head and Neck Cancer
Published 2024-10-01“…<b>Conclusion:</b> Despite these promising findings, challenges persist, such as HSI’s sensitivity to external conditions, the need for high-resolution and high-speed imaging, and the lack of comprehensive spectral databases. Future research should emphasize dimensionality reduction techniques, the integration of multiple machine learning models, and the development of extensive spectral libraries to enhance HSI’s clinical utility in HNC diagnostics. …”
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Decoding the diagnostic biomarkers of mitochondrial dysfunction related gene variants in pediatric T cell acute lymphoblastic leukemia
Published 2025-07-01“…The intersection of LASSO regression and RF algorithms highlighted two pivotal genes: RNLS and ULK1. …”
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Integrated Bioinformatics and Experimental Validation Reveal Macrophage Polarization-Related Biomarkers for Osteoarthritis Diagnosis
Published 2025-08-01“…Least absolute shrinkage and selection operator (LASSO), random forest (RF), and support vector machine recursive feature elimination (SVM-RFE) algorithms were used to identify hub genes and construct a diagnostic model validated through internal datasets and multiple external bulk RNA-seq and single-cell RNA-seq data. …”
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Eosinophilic Fasciitis: A Review of Research and Therapeutic Possibilities
Published 2024-12-01“…Current treatment mainly consists of corticosteroids, but further research is needed to assess various therapeutic strategies. …”
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Diagnosing schizophrenia with routine blood tests: a comparative analysis of machine learning algorithms
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Implementing the Result Decoding Algorithm of the Conditioned and Unconditioned Quest in Controling the Discipline Competence Level
Published 2015-03-01“…In addition, the algorithm of filling the matrix is illustrated along with the correlation of diagnostic indices and ratings with the assessment scales; the decoding algorithm of the unconditional testing procedure is described including the computation examples and outcome analysis. …”
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Identification of Serum miRNAs as Effective Diagnostic Biomarkers for Distinguishing Primary Central Nervous System Lymphoma from Glioma
Published 2022-01-01“…Invasive surgical cerebrum biopsy results in delayed treatment for the definitive diagnosis of primary central nervous system lymphoma (PCNSL). The existent research was aimed at confirming the underlying diagnostic miRNAs of distinguishing PCNSL from glioma. …”
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PRe-hospital Evaluation of Sensitive TrOponin (PRESTO) Study: multicentre prospective diagnostic accuracy study protocol
Published 2019-10-01“…The Troponin-only Manchester Acute Coronary Syndromes (T-MACS) decision rule is a validated tool used in the emergency department (ED) to stratify patients with suspected ACS following a single blood test.We are seeking to evaluate the diagnostic accuracy of the T-MACS decision aid algorithm to ‘rule out’ ACS when used in the prehospital environment with point-of-care troponin assays. …”
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