Effects of Supplementary Irrigation and some Stress Modifiers (Vermicompost, Nano Iron Oxide, and Humic Acid) on Grain Filling Components, Nodulation and Grain Yield of Chickpea (C... by R Seyed Sharifi, R Seyedsharifi

“…The chickpea cultivar ‘Adel’ was planted with the optimal density of 35 seeds.m-2. Vermicompost was prepared by Gilda Corporation and nano iron oxide from Pishgaman Nanomaterials Company. …”
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The Emergence of AI-Driven Virtual Hospitals: Redefining Patient Care Beyond Physical Boundaries by Ifrah Hameed, Hafiz Muhammad Haseeb Khaliq

“…For a similar reason, Apollo Hospitals in India have aimed to double their investment in AI-driven assistance to alleviate the workload of medical staff by automating simple tasks like medical documentation. …”
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Diagnostic Efficacy of Staging Laparoscopy Compared to CT and PET-CT in Gastric Cancer: A Retrospective Cohort Analysis by Cem Batuhan Ofluoğlu, Isa Caner Aydın, Fırat Mülküt, Orhan Uzun, Aziz Serkan Senger, Selçuk Gülmez, Uğur Duman, Erdal Polat, Mustafa Duman

“…<i>Background and Objectives</i>: This study aimed to assess the diagnostic accuracy and prognostic significance of staging laparoscopy (SL) compared to computed tomography (CT) and positron emission tomography–computed tomography (PET-CT) in gastric cancer staging. …”
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Evidence-based medicine: 5 steps to navigate uncertainty by Rafael Martín-Masot, Carlos Ochoa Sangrador, Jaime Javier Cuervo Valdés, Carolina Blanco Rodríguez, Paz González Rodríguez, Javier González de Dios, M. Salomé Albi Rodríguez, Pilar Aizpurua Galdeano, María Aparicio Rodrigo, Nieves Balado Insunza, Albert Balaguer Santamaría, Fernando Carvajal Encina, Eduardo Cuestas Montañes, M. Jesús Esparza Olcina, Sergio Flores Villar, Garazi Frailea Astorga, M. Victoria Martínez Rubio, Manuel Molina Arias, Eduardo Ortega Páez, Begoña Pérez-Moneo Agapito, M. José Rivero Martín, Álvaro Gimeno Díaz de Atauri, Laura Cabrera Morente, Elena Pérez González, Juan Ruiz-Canela Cáceres

“…In demanding clinical settings, evidence-based medicine aims to balance care quality, efficiency, and resource management, supporting professionals in making optimal, evidence-based decisions to improve health care. …”
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Combined thrombus fragmentation and catheter-directed thrombolysis in the treatment of pulmonary thromboembolism in high- and moderate-risk patients by V. Dimitrova, B. Vodenicharova, D. Dimitrov, P. Krastev

“…High mortality with a conservative approach in patients with high-risk PE and contraindications for fibrinolysis, as well as moderate-risk patients with a lack of clinical response to optimal anticoagulant therapy, requires a more selective treatment approach to ensure an inevitable positive hemodynamic response. …”
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Prediction of sinus rhythm maintenance after radiofrequency ablation in patients with atrial fibrillation using speckle tracking echocardiography and dynamics of left atrial struct... by T. I. Musin, Z. A. Bagmanova, D. A. Gareev, V. G. Rudenko, N. Sh. Zagidullin

“…Aim. To evaluate the dynamics of left atrial volume (LAV), strain (S) during the reservoir phase and strain rate (SR) in patients with paroxysmal and persistent atrial fibrillation (AF), scheduled for catheter radiofrequency ablation (RFA), as well as to compare the predictive value of S and SR as a marker of maintaining sinus rhythm.Material and methods. …”
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Evaluation of the Prebiotic Effect of Spirulina platensis Algal Extract on Lactobacillus acidophilus Survival and Physicochemical Properties of Feta Cheese by Ahmad Yazdani, Hamidreza Kazemeini, Ahmad Nazaktabar

“…It is also known that the optimal balance in the number of microbes in the digestive system depends on nutrition and health. …”
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Skrining Bakteri Termohalofilik Penghasil L-asparaginase dari Sumber Air Panas Wawolesea Sulawesi Tenggara dan Uji Aktivitas Enzimnya by Muzuni Muzuni, Jamaluddin Jamaluddin, Suriana Suriana, Ardiansyah Ardiansyah, Nur Arfa Yanti

“…The use of L-asparaginase on an industrial scale prioritizes L-asparaginase that exhibits optimal activity and stability at high temperatures due to the high reaction rate in hydrolyzing L-asparagine, stability against denaturants such as detergents and organic compounds, and stability under acidic or basic conditions. …”
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Protective Effects of GalNac-Modified Red Blood Cell-Derived Extracellular Vesicles Against Liver Diseases by Huang X, Yang J, Hu Y, Li S, Cai Z, Li C, Qin W, Zhang G

“…Extracellular vesicles (EVs) are optimal drug delivery vehicles, albeit with insufficient targeting specificity. …”
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Utilizing tumor deposit count as a stratification criterion in revising TNM staging system for patients with colorectal cancer: a nomogram review study by Lifei Zhang, Lifei Zhang, Yunna Ma, Jiantao Dong, Jiantao Dong, Jianhui Cai, Jianhui Cai, Jianhui Cai, Jianhui Cai

“…The dynamic nomogram could assist medical practitioners in diagnosing, providing prognoses, and optimizing treatment strategies more quickly and effectively.…”
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Development, Validation and Approbation Analytical Method for the Quantitative Determination of Taurine by HPLC-UV Method in the Test of Comparative Dissolution Kinetics by A. M. Poluyanov, A. Kochug, L. S. Mitrofanova, I. D. Nikitin, O. Yu. Vergasov, I. E. Shohin, E. N. Fisher

“…To solve this problem, one can apply the method of pre-column derivatization, because of which an fragment is introduced into the structure, providing a bathochromic shift in the UV spectrum of the starting compound.Aim. Development, validation and approbation analytical method for the quantitative determination of taurine by high-performance chromatography with ultraviolet detection as part of a test comparative kinetics dissolution of taurine tablets with a dosage of 250 and 500 mg.Materials and methods. …”
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Unlocking renewable energy potential: Overcoming knowledge sharing hurdles in rural EU regions on example of poland, sweden and france. by Justyna Żywiołek, Radosław Wolniak, Wieslaw Wes Grebski, Sunil Tiwari, Marek Matuszewski, Adam Koliński

“…The optimal technological choice for sustainable development lies in renewable energy sources (RES). …”
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Immunohistochemical analysis of PD-L1, CD4, CD8, CD20, and PU.1 expression in a dedifferentiated chondrosarcoma: the clinical and prognostic value by Olga V. Kovaleva, Irena V. Boulytcheva, Dmitrii V. Rogozhin, Alexei N. Gratchev, Polina L. Prishchep, Nikolay E. Kushlinskii

“…The IHC analysis was performed in the automated mode with a Ventana Bench Mark ULTRA IHC stainer (Ventana Medical Systems, USA) using an optimized protocol and anti-PD-L1 antibodies (clone SP142) and in the manual mode for staining with anti-PU.1, CD4, CD8 and CD20 antibodies. …”
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Biomarker, efficacy and safety analysis of transcatheter arterial chemoembolization combined with atezolizumab and bevacizumab for unresectable hepatocellular carcinoma by Shaobo Zhang, Zebin Zhu, Lianxin Liu, Björn Nashan, Shugeng Zhang

“…However, there is currently no published research on biomarkers that can predict the treatment outcomes of Atezo-Bev-TACE. This study aims to evaluate the predictive value of the baseline neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) in uHCC patients undergoing Atezo-Bev-TACE treatment. …”
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Final shade and whiteness: impact of various ultra-thin CAD/CAM veneers and tooth-colored resin substrates by Yinghui Wang, Xia Wei, Linjuan Gao, Dingkun Liu, Xing Chen, Liujun Lin, Yu Pan, Hao Yu, Guang Hong, Hui Cheng

“…Abstract Background Achieving optimal color control in chairside CAD/CAM ultra-thin veneers, remains a significant challenge for dental clinicians and technicians. …”
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Independent Association of Sleep Apnea-Specific Hypoxic Burden and Sleep Breathing Impairment Index with Thyroid Function in Obstructive Sleep Apnea: A Retrospective Study by Zhou Y, Shi Y, Zhu S, Cao Z, Xie Y, Lu C, Niu X, Ma L, Wang Z, Su Y, Xia Z, Yuan Y, Yang J, Lu R, Feng Y, Ren X, Hou W

“…Future research should further explore these mechanisms to optimize clinical management and treatment strategies for patients with OSA.Keywords: obstructive sleep apnea, sleep apnea-specific hypoxic burden, sleep breathing impairment index, thyroid function…”
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Impact of tumor diameter on post-radiofrequency ablation survival and local progression risk in patients with colorectal cancer lung metastasis by YING Leilei, LI Kening, CHEN Chao, WANG Ying, HUANG Haozhe, WANG Biao, LI Wentao, HE Xinhong

“…A tumor diameter of 3 cm can serve as a critical threshold for selecting RFA indications, and combining preoperative CEA levels can optimize patient stratification.…”
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Exergame (ExerG)-Based Physical-Cognitive Training for Rehabilitation in Adults With Motor and Balance Impairments: Usability Study by Silvia Herren, Barbara Seebacher, Sarah Mildner, Yanick Riederer, Ulrike Pachmann, Nija Sonja Böckler, Stephan Niedecken, Sabrina Alicia Sgandurra, Leo Bonati, Isabella Hotz, Alexandra Schättin, Roman Jurt, Christian Brenneis, Katharina Lenfert, Frank Behrendt, Stefan Schmidlin, Lennart Nacke, Corina Schuster-Amft, Anna Lisa Martin-Niedecken

“…The findings will inform future optimizations. Future work will assess long-term impact.…”
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The role of adipose-derived stem cells in knee osteoarthritis treatment: insights from a triple-blind clinical study by Simin Sajadi, Mohammad Amin Khadembashiri, Gholamreza Raissi, Mohamad Mehdi Khadembashiri, Korosh Mansouri, Homayoun Hadizadeh-Kharazi, Mohammad Taghi Joghataei, Seyed Pezhman Madani, Bijan Forogh, Sina Parsipour

“…While MSCs from bone marrow and umbilical cord have shown efficacy in treating OA, adipose-derived MSCs (ADMSC) are more accessible and cost-effective. This study aims to evaluate the safety and efficacy of allogeneic ADMSC in treating knee OA. …”
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Regulatory T Cell Responses in Participants with Type 1 Diabetes after a Single Dose of Interleukin-2: A Non-Randomised, Open Label, Adaptive Dose-Finding Trial. by John A Todd, Marina Evangelou, Antony J Cutler, Marcin L Pekalski, Neil M Walker, Helen E Stevens, Linsey Porter, Deborah J Smyth, Daniel B Rainbow, Ricardo C Ferreira, Laura Esposito, Kara M D Hunter, Kevin Loudon, Kathryn Irons, Jennie H Yang, Charles J M Bell, Helen Schuilenburg, James Heywood, Ben Challis, Sankalpa Neupane, Pamela Clarke, Gillian Coleman, Sarah Dawson, Donna Goymer, Katerina Anselmiova, Jane Kennet, Judy Brown, Sarah L Caddy, Jia Lu, Jane Greatorex, Ian Goodfellow, Chris Wallace, Tim I Tree, Mark Evans, Adrian P Mander, Simon Bond, Linda S Wicker, Frank Waldron-Lynch

“…Primary analysis of the evaluable population (n = 39) found that the optimal doses of aldesleukin to induce 10% and 20% increases in Tregs were 0.101 × 106 IU/m2 (standard error [SE] = 0.078, 95% CI = -0.052, 0.254) and 0.497 × 106 IU/m2 (SE = 0.092, 95% CI = 0.316, 0.678), respectively. …”
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