The role of muscle tissue in the pathogenesis of chronic heart failure — the potential of exposure (FORMA study) by T. A. Lelyavina, M. Yu. Sitnikova, V. L. Galenko, P. S. Kozlov, M. A. Bortsova, E. A. Demchenko, O. S. Ganenko, A. S. Golovkin, A. A. Kostareva, R. I. Dmitrieva

“…The study included 297 patients with stable III functional class (FC) CHF, receiving optimal therapy. The presence of heart failure was found in all patients at least 6 months before the start of the study (age — 18-65 years, body mass index (BMI) — 19-28 kg/height, m2. …”
Get full text

Exploring the Feasibility of a 5-Week mHealth Intervention to Enhance Physical Activity and an Active, Healthy Lifestyle in Community-Dwelling Older Adults: Mixed Methods Study by Kim Daniels, Sharona Vonck, Jolien Robijns, Kirsten Quadflieg, Jochen Bergs, Annemie Spooren, Dominique Hansen, Bruno Bonnechère

“… BackgroundAdvancements in mobile technology have paved the way for innovative interventions aimed at promoting physical activity (PA). …”
Get full text

Prognostic value and immunotherapy analysis of immune cell-related genes in laryngeal cancer by Sen Zhang, Jianrui Pan, Huina Guo, Xiaoya Guan, Chenxu Yan, Lingling Ji, Xiansha Wu, Hui Huangfu

“…Machine learning indicated that the optimal prognostic model was constructed from two biomarkers, RENBP and OLR1. …”
Get full text

Growth and body composition of adolescents and young adults with perinatal HIV infection: a systematic review and meta-analysis by Priscila R. F. Costa, Nathalia S. Guimarães, Carlos R. N. Lira, Luana O. Leite, Rita de Cássia Ribeiro da Silva, Maurício L. Barreto, Enny S. Paixão

“…Although there was a modest increase in height-for-age, persistent challenges in achieving optimal growth remain. The slight improvement in BMI is insufficient to fully address underweight concerns. …”
Get full text

The Assessment of the Effects of Implementing Special Improvement Plan on Rural Housing Development (Case Study: Abrisham Rural District) by Farhad Azizpour, Zohreh Sadeghi

“…This plan was implemented in the rural areas from 2005 to 2011 with the aim of retrofitting, preserving the identity of native architecture, promoting environmental health, optimizing energy consumption, and so forth. …”
Get full text

Evaluating the Health Implications of Kombucha Fermented with <i>Gardenia jasminoides</i> Teas: A Comprehensive Analysis of Antioxidant, Antimicrobial, and Cytotoxic Properties by Gayathree Thenuwara, Xu Cui, Zhen Yao, Bilal Javed, Azza Silotry Naik, Furong Tian

“…<b>Background/Objectives:</b> Plant-derived compounds are increasingly valued in drug discovery for their therapeutic potential. This study aims to examine the antimicrobial, antioxidant, and anticancer properties of kombucha beverages fermented with Gardenia jasminoides (GJ) and various types of <i>Camellia sinensis</i> teas: matcha green tea (MGT), organic green tea (OGT), and decaffeinated green tea (DGT). …”
Get full text

From gaps to compliance: a 12-year retrospective cohort study of trends in mismatch repair protein testing and Lynch syndrome identification in colorectal cancer in Central Switzer... by Bettina Marturet Fendt, Celina Geiss, Muriel Elhai, Joachim Diebold, Alexander Vogetseder

“… STUDY AIM: Alongside an analysis of incidence trends in colorectal cancer and Lynch syndrome over time, the study sought to evaluate the implementation and trends of reflex testing for mismatch repair proteins and key mutations in relevant genes (BRAF, KRAS, NRAS) in colorectal cancer in Central Switzerland from 2011 to 2022, specifically assessing adherence to the Swiss Academy for Quality in Medicine (SAQM) guidelines, in order to identify any gaps or inconsistencies in testing practices that may hinder the diagnosis of Lynch syndrome or microsatellite instability, highlighting areas requiring improvements for optimal patient care. …”
Get full text

Automated Digital Safety Planning Interventions for Young Adults: Qualitative Study Using Online Co-design Methods by Jonah Meyerhoff, Sarah A Popowski, Tanvi Lakhtakia, Emily Tack, Rachel Kornfield, Kaylee P Kruzan, Charles J Krause, Theresa Nguyen, Kevin Rushton, Anthony R Pisani, Madhu Reddy, Kimberly A Van Orden, David C Mohr

“…These tools should be designed in collaboration with young adults who have lived experience of suicide-related thoughts and behaviors to optimize acceptability and use. ObjectiveThis study aims to identify the needs, preferences, and features for an automated SMS text messaging–based safety planning service to support the self-management of suicide-related thoughts and behaviors among young adults. …”
Get full text

NIPT of Maternal Plasma-Originated cfDNA: Applications and Guide for the Implementation by Fernández Martínez FJ, Gil Mira MM, González González C, Madrigal Bajo I, Oancea Ionescu R, Orellana Alonso C

“…By establishing a minimum framework based on scientific evidence, this document aims to optimize NIPT implementation in a cost-effective manner, ensuring clinical validity and informed decision-making for both healthcare professionals and pregnant women.Keywords: prenatal diagnosis, non-invasive prenatal test, cell-free DNA, functional guide…”
Get full text

Visualized load-bearing-based robot control system improves early function in femoral neck fracture patients: a randomized controlled trial focusing on outcomes after total hip art... by Xiaofeng Liu, Changzhi Huang, Liang Lin, Jinshan Zhang, Zhenzhong Zhu

“…Sometimes, traditional treatment methods may not be sufficient to satisfactorily improve WBA and weight-bearing ratio (WBR) on the surgical side. This study aims to evaluate the effectiveness of a visualized load-bearing-based robot control system in promoting early functional recovery of elderly patients after THA. …”
Get full text

Elektroda Pasta Karbon Termodifikasi Bentonit Alam untuk Analisis Ion Pb(II) dalam Air Laut by Irdhawati Irdhawati, Ni Putu Gita Widi Saraswati, Emmy Sahara, Ayu Jyostisya Yotirani Arya Wijana

“…Optimized parameters were the concentration of natural bentonite in carbon paste, deposition time, deposition potential, and scan rate. …”
Get full text

Evaluation of seasonal variation, effect of extraction solvent on phytochemicals and antioxidant activity on Rosmarinus officinalis grown in different agro-ecological zones of Kiam... by Zelipha N. Kabubii, James M. Mbaria, Mbaabu P. Mathiu, John M. Wanjohi, Evans N. Nyaboga

“…The data provided in this study will be crucial for processors to select the optimal harvesting season for the extraction of desired bioactive compounds from Rosmarinus officinalis.…”
Get full text

The Roles of Vitamin D Levels, Gla-Rich Protein (GRP) and Matrix Gla Protein (MGP), and Inflammatory Markers in Predicting Mortality in Intensive Care Patients: A New Biomarker Lin... by Fatih Seğmen, Semih Aydemir, Onur Küçük, Recep Dokuyucu

“…Objectives: Identifying reliable biomarkers to predict mortality in critically ill patients is crucial for optimizing management in intensive care units (ICUs). …”
Get full text

Extracción fraccional de O2 y condición física entre niños activos e inactivos físicamente durante la recuperación post ejercicio (Fractional O2 extraction and fitness among physic... by Rodrigo Alejandro Yañez Sepulveda, Cristóbal Cortés-Morales, Benjamín Galindo-Guerrero, Tomás Olivares-Sepúlveda, Diego Zurita-Urmazábal, Ildefonso Alvear-Órdenes, Guillermo Cortés-Roco, Vicente Javier Clemente-Suárez, Claudio Hinojosa-Torres, Juan Pablo Zavala-Crichton, Jorge Olivares-Arancibia, Marcelo Tuesta

“…These findings underscore the potential of regular physical activity to optimize peripheral vascular response and muscle oxygen utilization during post-exercise recovery in children. …”
Get full text

Development a nomogram for predicting HELLP syndrome in women complicated with gestational hypertension by Ying Jiang, Lu-Jiao Chen, Hui-Hui Hu, Neng Jin, Shi-Rui Lv, Chen Fang, Chun-Mei Zhu, Meng-Meng Yang, Dong Xu, Qiong Luo

“…The AUC of the external validation dataset was 0.838 (95% CI: 0.785–0.892). The optimal cutoff value calculated using Youden’s index was 0.613, with a sensitivity of 0.891(95% CI: 0.473–0.836) and specificity of 0.722(95% CI: 0.667–0.818). …”
Get full text

FORMATION OF PROFESSIONAL COMPETENCE OF FUTURE VOCATIONAL TRAINING IN- VOCATIONAL TRAINING IN- STRUCTORS IN THE FIELD OF TRANSPORT USING DIGITAL TECHNOLOGIES by Pohorielov Mykhailo, Filatov Sergiy

“…Theoretical aspects of the research are complemented by an analysis of modern computer technologies in education, which significantly optimize the learning process for both instructors and students. …”
Get full text

EXPERIMENTAL STUDY OF EFFECTIVENESS OF DEEP FLUORIDATION OF ENAMEL DURING SECONDARY MINERALIZATION OF THE PERMANENT TEETH ENAMEL by H. V. Sorochenko

“…The chemical composition of the superficial layer of tooth enamel changed after using of methods of deep fluoridation of enamel. Achieving of the optimal level of mineralization under the influence of deep fluoridation occurs within 6-months of the experiment. …”
Get full text

EFFECTS OF LONG-TERM CONTINUOUS POSITIVE AIRWAY PRESSURE THERAPY (CPAP) ON EPICARDIAL FAT THICKNESS AND ARTERIAL STIFFNESS IN PATIENTS WITH OBSTRUCTIVE SLEEP APNEA AND HYPERTENSION by M. V. Gorbunova, S. L. Babak, A. G. Malyavin

“…The reactive hyperemia index (RHI) and augmentation index (AI) was calculated. Optimal level of A-Flex therapy was adjusted at home. …”
Get full text

Experiences of Oral Corticosteroid Use and Adverse Effects: A National Cross-Sectional Survey of People with Asthma by Jones AW, McDonald VM, McLoughlin RF, Vella TM, Flynn AW, Blakey JD, Wolfenden L, Hew M, Upham JW, Thomas D, Bardin P, Holland AE

“…People with asthma are not adequately informed about optimal OCS use or strategies to reduce overuse. These findings can help guide the implementation of OCS stewardship initiatives.Keywords: asthma, corticosteroids, consumer behaviour, attitude, patient participation…”
Get full text

Identification of age-specific risk factors for hyperuricemia: a machine learning-driven stratified analysis in health examination cohorts by ChuXia Tan, Yuan Liu, Lijun Li, Ying Li, Pingting Yang, Yinglong Duan, Xingxing Wang, Huiyi Zhang, Jingying Wang, Honglian Zhang

“…Abstract Background Hyperuricemia (HUA) as a global public health challenge, although its overall epidemiological characteristics have been widely reported, its age-specific risk pattern remains controversial. This study aims to reveal the risk factors of HUA in healthy physical examination populations of different age groups and construct a machine learning-driven risk prediction model to achieve precise intervention. …”
Get full text