Physiological effects and technical strategies of LED supplemental lighting for pitaya cultivation: a review by Ren Chen, Yiming Ding, Wenke Liu, Xianwei Zhan, Kexin Lin, Kaifeng Lian, Weilong Chen, Keyu Wang, Shangfei Lin

“…These strategies aim to improve the efficiency of LED lighting systems and provide a theoretical foundation for developing a precise and efficient pitaya LED supplemental lighting technology system. …”
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Synthesis, Anticancer Screening, and In Silico Evaluations of Thieno[2,3-<i>c</i>]pyridine Derivatives as Hsp90 Inhibitors by Balakumar Chandrasekaran, Mohammad F. Bayan, Ali Hmedat, Bilal A. Al-Jaidi, Deniz M. Al-Tawalbeh, Duaa Abuarqoub, Anas J. Rasras, Da’san M. M. Jaradat, Abdel Naser Dakkah, Wafa Hourani, Rajshekhar Karpoormath

“…<b>Background</b>: Thieno[2,3-<i>c</i>]pyridines and their analogs are not well explored for their anticancer properties. Hence, our research aimed to establish the anticancer potential of thieno[2,3-<i>c</i>]pyridines through cell-based assays and in silico evaluations. …”
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Ovarian Reserve: A Critical Indicator of Female Reproductive Health by Julia Ufnal, Anna Wolff, Maria Morawska, Dominika Lewandowska, Dominika Rosińska-Lewandoska, Marcelina Szewczyk, Klaudia Kożuchowska, Dawid Pilarz, Kinga Jarosz, Szymon Gruszka

“…Conclusions: Assessing ovarian reserve is crucial for predicting pregnancy outcomes, optimizing ART protocols, and guiding reproductive decisions. …”
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Discovery and validation of frameshift-derived neopeptides in Lynch syndrome: paving the way for novel cancer prevention strategies by Marta Pineda, Sabela Carballal, María Pellisé, Liseth Rivero, Francesc Balaguer, Fátima Marín, Leticia Moreira, Teresa Ocaña, Manel Juan, Daniel Benitez-Ribas, Georgina Flórez-Grau, Joaquín Castillo-Iturra, Cristina Bayó, Giancarlo Castellano, Hardeep Kumari, Maria Daca-Alvarez, Oswaldo Ortiz, Rebeca Moreira, Julia Canet-Hermida, Capella Gabriel

“…Cancer vaccines targeting FSDNs offer a promising approach for immune interception in LS. This study aimed to identify and validate LS-related FSDNs to develop vaccines for cancer prevention.Methods We identified LS-related coding MS mutations and predicted FSDN with high coverage on common Human Leukocyte Antigen (HLA)-I and II alleles. …”
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Evaluation of Patient Benefits from the Superficial Circumflex Iliac Artery Perforator Flap in Elderly Patients by Hongmin Luo, Huining Bian, Zuan Liu, Chuanwei Sun, Hanhua Li, Lianghua Ma, Xiaoyan Wang, Zhifeng Huang, Xu Mu, Shenghua Chen, Yuyang Han, Lin Zhang, Shaoyi Zheng, Zeyang Yao, Wen Lai

“…These findings support the continued use of SCIP flaps in aging populations, emphasizing the need for individualized surgical approaches to optimize patient outcomes.…”
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Impacts of the COVID-19 Pandemic on the CODE ST-Segment Elevation Myocardial Infarction Program: A Quantitative and Qualitative Analysis by Eka Ginanjar, Arif Mansjoer, Lusiani Rusdi, Rizky Ramadantie, Hadiki Habib, Lies Dina Liastuti, Sally Aman Nasution, Idrus Alwi, Abdul Rashid

“…The emerging coronavirus disease 2019 (COVID-19) outbreak brought about many changes in the management of healthcare services, including the CODE STEMI program. This study aimed to evaluate the healthcare service quality of the CODE STEMI program during the COVID-19 pandemic based on the Donabedian concept.  …”
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A comparison of healthcare resource utilization and costs between patients with chronic lymphocytic leukemia treated with first-line ibrutinib or acalabrutinib using two large US r... by Kerry A Rogers, Benyam Muluneh, Zaina P Qureshi, Jinghua He, Alex Bokun, Zhijie Ding, Marie-Helene Lafeuille, Priyanka Gogna, Bruno Emond, Michael Fradley

“…Aim: Real-world evidence comparing healthcare resource utilization (HRU) and costs between ibrutinib and acalabrutinib, two Bruton’s tyrosine kinase inhibitors for the treatment of chronic lymphocytic leukemia and small lymphocytic lymphoma (CLL/SLL) is limited. …”

Transcranial photobiomodulation improves functional brain networks and working memory in healthy older adults: An fNIRS study by Qin Yang, Xiujuan Qu, Can Sheng, Xing Zhao, Guanqun Chen, Xiaoni Wang, Yuxia Li, Wenying Du, Xiaoqi Wang, Yu Sun, Xiaobo Li, Haijing Niu, Ying Han

“…Objective: This randomized, single-blind, sham-controlled crossover study aimed to investigate the hypothesis that tPBM improved working memory in healthy older adults through the mechanism of optimizing the properties of the resting-state functional brain networks. …”
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Towards a universal implementation of labor companionship: a synthesis of the policy and facility environment of eight low-and-middle income countries by Soha El-Halabi, Andrea Barnabas Pembe, Alexandre Dumont, Ana Pilar Betrán, Charles Kaboré, Effie Chipeta, Guillermo Carroli, Helle Mölsted Alvesson, Hussein Kidanto, Jean-Paul Dossou, Kristi Sidney Annerstedt, Lenka Beňová, Mechthild M. Gross, Peter Waiswa, Pisake Lumbiganon, Quoc Nhu Hung Mac, Meghan A. Bohren, Claudia Hanson, Claudia Hanson

“…However, implementation remains sub-optimal, especially in low-and-middle-income countries (LMICs). …”
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Population pharmacokinetics of high-dose methotrexate in patients with primary central nervous system lymphoma by Shifeng Wei, Shifeng Wei, Sitian Zhang, Dan Wang, Dan Wang, Dongjie Zhang, Qian Lu, Jiayi Mo, Jiayi Mo, Zhilin Yang, Zhilin Yang, Leyi Guan, Yingjun He, Zhigang Zhao, Zhigang Zhao, Shenghui Mei, Shenghui Mei

“…The PPK models developed will aid in optimizing and personalizing HD-MTX treatment for PCNSL patients.…”
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Supplementation of DHA enhances the cryopreservation of yak semen via alleviating oxidative stress and inhibiting apoptosis by Yanjin Zhu, Yanjin Zhu, Jun Yu, Xupeng Li, Zhuo Chen, Yuan Li, Yan Xiong, Honghong He, Shi Yin, Daoliang Lan, Jian Li, Jian Li, Lixue Yang, Xianrong Xiong, Xianrong Xiong

“…However, the frozen-thawed process often leads to physical and chemical damage in semen, resulting in oxidative stress that diminishes sperm vitality and fertilization potential. This study aimed to explore the effects of docosahexaenoic acid (DHA) on the quality of frozen-thawed yak semen.MethodsSemen samples were collected from six healthy adult Maiwa yaks and cryopreserved in liquid nitrogen using extenders with varying DHA concentrations: 0, 0.1, 1, 10, and 100 ng/mL. …”
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Dietary black soldier fly oil enhances growth performance, flesh quality, and health status of largemouth bass (Micropterus salmoides) by Hailin Yuan, Junru Hu, Xiangce Li, Qiuxuan Sun, Xiaohong Tan, Cuihong You, Yewei Dong, Yanhua Huang, Meng Zhou

“…The study aimed to assess the effects of dietary black soldier fly oil (BSFO) on the growth performance, flesh quality, and health status of largemouth bass (Micropterus salmoides). …”
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Design and Validation of a Simplified Method to Determine Minimum Bactericidal Concentration in Nontuberculous Mycobacteria by Sara Batista, Mariana Fernández-Pittol, Lorena San Nicolás, Diego Martínez, Sofía Narváez, Mateu Espasa, Elena Garcia Losilla, Marc Rubio, Montserrat Garrigo, Griselda Tudó, Julian González-Martin

“…Treating NTM infections is challenging due to their poor response to antibiotics. This study aimed to optimize the treatment of NTM infection by selecting antibiotics with bactericidal activity for combination therapy. …”
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Diabetes management during and after Ramadan among pregnant women in Saudi Arabia: exploring self-efficacy, self-care, and glycemic control by Omar Mohammed Alamri, António Raposo, Ayoub Ali Alshaikh, Hani A. Alfheeaid, Ali Mohammed Alamri, Mohammed Abdullah Alasmri, Nada Mohammed Alwubayran, Ahmed Khaled Shukri, Thamer Alslamah, Najla A. Albaridi, Md Faruque Ahmad, Abdullah Y. Otayf, Ariana Saraiva, Ariana Saraiva, Najim Z. Alshahrani

“…Sustained education, individualized care, and preparation before Ramadan were linked to better outcomes, highlighting the importance of ongoing support beyond the fasting period for optimal diabetes management.…”
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Microbiological aspects and clinical impact of lower lung field tuberculosis: An observational cohort study in Peru by Qi Tan, Chuan-Chin Huang, Roger Calderon, Leonid Lecca, Milagros Mendoza, Gabriela Reyes Rocha, Karen Tintaya, Ximena Tovar, Jia-Yih Feng, Sheng-Wei Pan, Yen-Han Tseng, Jhong-Ru Huang, Zibiao Zhang, Megan B. Murray

“…It may contribute to increased TB transmission and mortality. We aimed to identify microbiological determinants of LLF TB and evaluate treatment responses to optimize care. …”
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Predictive Factors for Super Responder Status and Long-Term Effectiveness of Guselkumab in Psoriasis: A Multicenter Retrospective Study by Edoardo Mortato, Marina Talamonti, Lorenzo Marcelli, Matteo Megna, Annunziata Raimondo, Giacomo Caldarola, Nicoletta Bernardini, Anna Balato, Anna Campanati, Maria Esposito, Claudio Bonifati, Viviana Lora, Luca Potestio, Serena Lembo, Francesco Loconsole, Eleonora De Luca, Nevena Skroza, Dario Buononato, Tommaso Bianchelli, Maria Concetta Fargnoli, Nello Tommasino, Felice Primavera, Clara De Simone, Luca Bianchi, Marco Galluzzo

“…However, preliminary identification of super responders (SRe: patients achieving PASI 100 at week 20) can help optimize treatment strategies. This study aims to identify predictive factors for SRe status in patients receiving guselkumab therapy for psoriasis and to evaluate long-term effectiveness in the entire cohort and both SRe and non-super-responder (nSRe) groups to understand whether SRe status is also a predictor of long-term response to guselkumab in a real-world setting. …”
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Knowledge and Practice Regarding Pressure Injury Prevention among Nurses at King Abdul-Aziz Specialist Hospital by Afnan Sahrah, Wafaa Althobaiti, Sahar Albalawi, Ensherah Althobiti, Turki Alfattah, Abdulellah Almalki, Ahlam Alotaibi, Maha Alkhaldi, Talal Alqurashi, Faten Sahrah, Munirah Alfifi, Rami Alnemari, Alaa Alzahrani

“…Thus, prevention requires an interdisciplinary approach to care. Aim: To determine knowledge and practice regarding pressure injury prevention among nurses at King Abdulaziz Specialist Hospital (KAASH).  …”
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Investigation of statistical methods used in prognostic prediction models for obstetric care: A 10 year‐span cross‐sectional study by Jing Tan, Chunrong Liu, Min Yang, Yiquan Xiong, Shiyao Huang, Yana Qi, Meng Chen, Lehana Thabane, Xinghui Liu, Lin He, Xin Sun

“…Conclusions The use of statistical methods is not yet optimal. Ten recommendations were offered to assist the statistical methods of prognostic prediction models in obstetric care.…”
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Breast tumors from ATM pathogenic variant carriers display a specific genome-wide DNA methylation profile by Nicolas M. Viart, Anne-Laure Renault, Séverine Eon-Marchais, Yue Jiao, Laetitia Fuhrmann, Sophia Murat El Houdigui, Dorothée Le Gal, Eve Cavaciuti, Marie-Gabrielle Dondon, Juana Beauvallet, Virginie Raynal, Dominique Stoppa-Lyonnet, Anne Vincent-Salomon, Nadine Andrieu, Melissa C. Southey, Fabienne Lesueur

“…Germline biallelic inactivation of the ATM gene causes ataxia-telangiectasia (A-T), and heterozygous pathogenic variant (PV) carriers are at increased risk of cancer, notably breast cancer. This study aimed to investigate whether DNA methylation profiling can be useful as a biomarker to identify tumors arising in ATM PV carriers, which may help for the management and optimal tailoring of therapies of these patients. …”
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Fecal microbiota is more stable during degradation and more diverse for ex situ cheetahs in Namibia compared to the USA by Morgan A. Maly, Morgan A. Maly, Morgan A. Maly, Morgan A. Maly, Reade B. Roberts, Mia M. Keady, Anne Schmidt-Küntzel, Meagan Maxwell, Laurie Marker, Matthew Breen, Carly R. Muletz-Wolz, Adrienne E. Crosier

“…Unfortunately, fresh samples are challenging to collect in the wild. This study had two aims: 1) to determine the optimal collection time point for cheetah feces after deposit in their native environment of Namibia as a guide for wild cheetah fecal microbiome studies; and 2) to compare the fecal microbiota of two ex situ cheetah populations (Front Royal, VA, USA and Otjiwarongo, Namibia), which also consume different diets. …”
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