Primary Mediastinal (Thymic) Large B-Cell Lymphoma: Experience in Treating 131 Patients at a National Medical Research Center in Russia by IZ Zavodnova, MYu Kichigina, EV Paramonova, YuE Ryabukhina, OA Kolomeitsev, OP Trofimova, NV Volkova, YuI Pryamikova, NV Kokosadze, GS Tumyan

“…The advantages of one immunochemotherapy regimens over the other in controlled studies have not been shown. Aim. To study current approaches to chemoradiation in PMBCL patients with an attempt to individualize them focusing on various prognostic factors. …”
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“Comprehensive Analysis of Factors Influencing Recurrence and Survival in Glioblastoma: Implications for Treatment Strategies”: A Single Center Study by Ahmed Bendari, Sunder Sham, Hamed Hammoud, Oana Vele, Brett Baskovich, David Huang, Alaa Bendari, Rachel Saks, Reham Al-Refai, Tasneem Bendari, Layth Kataw, Fnu Kiran, Fnu Anjali, Sanjay Kirshan Kumar, Manju Harshan

“…Understanding these factors could aid in optimizing treatment strategies and improving patient outcomes. …”
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Efficacy and safety of intensive triglyceride-lowering therapy on reducing recurrence of hypertriglyceridemia-associated pancreatitis (REDUCE): protocol for a multicentre, randomis... by Tao Chen, Weiqin Li, Chunping Zhu, Na Liu, Xin Xu, Lihui Deng, Dong Wu, Yao Wu, Jianhua Wan, Xin Huang, Lu Ke, Wenhua He, Hongwei Zhang, Duan Wang, Nong-Hua Lu, Yin Zhu, Ling Ding, Jianing Li, Jianwen Sheng, Nonghua Lu, Huifang Xiong, Liang Xia, Gaifang Liu, Jinyi Sheng, Lingyu Luo, Yupeng Lei, Huajing Ke, Lanting Wang, Shihang Zhang, Zhihua Tang, Youshun Liu, Guan Gui, Yingjie Chen, Yinyu Pan

“…Uncontrolled HTG after hospital discharge is an important risk factor for recurrence. However, the optimal triglyceride (TG) goal of lipid-lowering therapy for outpatients remains unclear. …”
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Donafenib versus sorafenib in triple therapy for unresectable hepatocellular carcinoma: a propensity score-matched multicenter analysis by Yaohong Wen, Shuyi Zhou, Yuyan Xu, Cheng Zhang, Zhoubin Feng, Yinghui Song, Bai Ding, Chuang Peng, Hongkun Tan, Chunming Wang, Jianan Feng, Jingyuan Pei, Guolin He, Shunjun Fu, Lvhuan Wang, Lei Cai, Sulai Liu, Mingxin Pan

“…Abstract Background In recent years, triple therapy (molecular targeted agent + PD-1 inhibitor + transarterial therapy) has emerged as a promising strategy for unresectable hepatocellular carcinoma (uHCC). However, the optimal molecular targeted agent choice within triple therapy remains unclear. …”
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Prognostic nutritional index in the prediction of adverse cardiac and cerebrovascular events in ST-segment elevation myocardial infarction patients with type 2 diabetes mellitus in... by Ling Zhao, Teng Yuan, Bang-Hao Zhao, Amanguli Ruze, Qiu-Lin Li, An-Xia Deng, Su Hu, Xiao-Ming Gao

“…The multivariate Cox regression analysis revealed that PNI was an independent predictor of MACCE (adjusted HR 0.95, 95% CI 0.93 to 0.97, p<0.001) and all-cause death (adjusted HR 0.93, 95% CI 0.90 to 0.97, p<0.001). The optimal PNI cut-off for predicting MACCE and all-cause death was 45.10 and 45.09, respectively. …”
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Characteristics and Outcome of Partial Liver Transplant among Pediatrics in a Referral Transplant Center in Iran from 2010 to 2020 by Pooya Vatankhah, Mohammad Bagher Khosravi, Mohammad Hossein Eghbal, Naeimehossadat Asmarian, Mohammad Ali Sahmeddini, Fatemeh Khalili, Samaneh Ghazanfar Tehran, Hamed Nikoupour, Alireza Shamsaeefar, Kourosh Kazemi, Sahar Sohrabi Nazari, Saman Nikeghbalian, Seyed Ali Malekhosseini

“…Background: Liver transplantation (LT) is a critical intervention for pediatric patients with advanced liver failure. This study aimed to assess the impact of perioperative factors on LT outcomes in pediatric patients.Methods: This retrospective cohort study, conducted from 2010-2020, included 563 pediatric patients who underwent LT in Shiraz, Iran. …”
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Fetal cardiovascular magnetic resonance feature tracking myocardial strain analysis in congenital heart disease by Thomas M. Vollbrecht, Christopher Hart, Christoph Katemann, Alexander Isaak, Claus C. Pieper, Daniel Kuetting, Ulrike Attenberger, Annegret Geipel, Brigitte Strizek, Julian A. Luetkens

“…ABSTRACT: Background: Cardiovascular magnetic resonance (CMR) is an emerging imaging modality for assessing the anatomy and function of the fetal heart in congenital heart disease (CHD). This study aimed to evaluate myocardial strain using fetal CMR feature tracking (FT) in different subtypes of CHD. …”
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Conservative treatments for women with stress urinary incontinence: a systematic review and network meta-analysis by Mengzhen Li, Mengzhen Li, Kexin Qiu, Kexin Qiu, Haoran Guo, Haoran Guo, Mengsi Fan, Mengsi Fan, Li Yan, Li Yan

“…ObjectiveThis study aimed to compare the effectiveness of various conservative treatment strategies for women with stress urinary incontinence.MethodsA comprehensive search of PubMed, Web of Science, Embase, and the Cochrane Library was conducted from their inception through March 2024, without restrictions on language or location. …”
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Guidance for the gastrointestinal evaluation and management of iron deficiency in Sub-Saharan Africa by W M Simmonds, Y Awuku, C Barrett, M Brand, K Davidson, D Epstein, E Fredericks, S Gabriel, S Grobler, C Gounden, L Katsidzira, V J Louw, V Naidoo, C Noel, E Ogutu, N Ramonate, N Seabi, M Setshedi, J Van Zyl, G Watermeyer, C Kassianides

“…Integration of the recommendations is intended to promote optimal evaluation and management of patients with ID, regardless of the presence of anaemia. …”
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Transcutaneous electrical nerve stimulation as an adjuvant treatment for thoracolumbar acute hyperesthesia in chondrodystrophic dogs: a prospective blinded controlled clinical stud... by Débora Gouveia, Débora Gouveia, Débora Gouveia, Ana Cardoso, Ana Cardoso, Carla Carvalho, Marina Moisés, André Coelho, André Coelho, André Coelho, Maria Manuel Balça, Maria Manuel Balça, Maria Manuel Balça, Rui Alvites, Rui Alvites, Rui Alvites, Rui Alvites, Ana Colette Maurício, Ana Colette Maurício, Ana Colette Maurício, António Ferreira, António Ferreira, Ângela Martins, Ângela Martins, Ângela Martins

“…Further research with objective outcome measures is necessary to validate these findings and optimize the integration of TENS in veterinary pain management protocols.…”
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CT-based radiomics deep learning signatures for non-invasive prediction of metastatic potential in pheochromocytoma and paraganglioma: a multicohort study by Yongjie Zhou, Yuan Zhan, Jinhong Zhao, Linhua Zhong, Fei Zou, Xuechao Zhu, Qiao Zeng, Jiayu Nan, Lianggeng Gong, Yongming Tan, Lan Liu

“…Abstract Objectives This study aimed to develop and validate CT-based radiomics deep learning signatures for the non-invasive prediction of metastatic potential in pheochromocytomas and paragangliomas (PPGLs). …”
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Reduction of mangrove carbon stock ecosystems due to illegal logging using a combination of unmanned aerial vehicle imagery and field surveys by M. Basyuni, R. Amelia, A.A. Aznawi, A. Wirasatriya, S.B. Iryanthony, B. Slamet, S.S. Al Mustaniroh, R. Rahmania, Y.I. Rahmila, E. Sumarga, S.H. Larekeng, S. Salmo III, T. Kajita, I. Sivaipram, H.M. Ali

“…Careful deployment of flight paths to obtain high accuracy in optimal image capture overlapped with 90 percent was conducted from August 5 to 8, 2023. …”
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A multicentre implementation trial of an Artificial Intelligence-driven biomarker to inform Shared decisions for androgen deprivation therapy in men undergoing prostate radiotherap... by Eric Wegener, Michael Ng, Mario Guerrieri, Timothy N. Showalter, Jeremy de Leon, Sagar Ramani, Marcus Dreosti, Tee Lim, Bradley Wong, Michael Chao, Kathryn Hogan, Avi Raman, Scott McClintock, Darren Foreman, Matthew Brown, Stephen McCombie, Kevin McMillan, Kieran Beattie, Mark Frydenberg, Lih-Ming Wong, Dickon Hayne, John Yaxley, Phillip Stricker, Jarad Martin

“…Methods This multicentre implementation trial aims to collect real-world data on the use of the previously validated Artera MMAI-driven prognostic and predictive biomarkers in men with intermediate-risk prostate cancer undergoing curative radiotherapy. …”
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Test accuracy of loop-mediated isothermal amplification for schistosomiasis in low endemicity areas: a systematic review and meta-analysis by Xinjie Zhou, Jiajia Li, Jiayin Qiu, Ting Feng, Chao Lv, Wangping Deng, Robert Bergquist, Jing Xu, Shizhu Li, Zhiqiang Qin

“…Subgroup analyses revealed optimal performance for S. japonicum and snail samples with lower heterogeneity (I 2  < 50%). …”
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CircEPDR1 regulates proliferation and differentiation of goat skeletal muscle satellite cells through miR-345-3p/Akirin1 axis by Song Shi, Diansong Duan, Jing Luo, Zihao Zhao, Tao Ma, Dinghui Dai, Siyuan Zhan, Jiaxue Cao, Jiazhong Guo, Tao Zhong, Linjie Wang, Hongping Zhang, Li Li

“…Objective Circular RNAs (circRNAs) play pivotal roles in regulating the growth and development of mammalian skeletal muscle This study aims to provide new insights into the molecular regulatory network that underlies skeletal muscle development, presenting valuable targets to enhance and optimize livestock production performance. …”
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The preoperative hemoglobin, albumin, lymphocyte, and platelet score (HALP) as a prognostic indicator in patients with non-small cell lung cancer by Qiteng Liu, Qiteng Liu, Qiteng Liu, Qiteng Liu, Hailun Xie, Hailun Xie, Hailun Xie, Wenjuan Cheng, Tong Liu, Tong Liu, Tong Liu, Chenan Liu, Chenan Liu, Chenan Liu, Heyang Zhang, Heyang Zhang, Heyang Zhang, Shiqi Lin, Shiqi Lin, Shiqi Lin, Xiaoyue Liu, Xiaoyue Liu, Xiaoyue Liu, Haiying Tian, Haiying Tian, Haiying Tian, Xiangrui Li, Xiangrui Li, Xiangrui Li, Xin Zheng, Xin Zheng, Xin Zheng, Yue Chen, Yue Chen, Yue Chen, Jinyu Shi, Jinyu Shi, Jinyu Shi, Hong Zhao, Hong Zhao, Hong Zhao, Hanping Shi, Hanping Shi, Hanping Shi

“…The 1-, 2-, 3-, and 5-year survival rates for patients with NSCLC were 68.6, 48.6, 37.4, and 30.9%, respectively. The optimal cut-off for HALP was determined to be 29.71, with a sensitivity of 53.1% and specificity of 62.9%, leading to the categorization of patients into low (&lt;29.71) (n = 963) and high (≥29.71) (n = 1,090) HALP groups. …”
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Local QSAR based on quantum chemistry calculations for the stability of nitrenium ions to reduce false positive outcomes from standard QSAR systems for the mutagenicity of primary... by Shigeharu Muto, Ayako Furuhama, Mika Yamamoto, Yasuteru Otagiri, Naoki Koyama, Seiji Hitaoka, Yusuke Nagato, Hirofumi Ouchi, Masahiro Ogawa, Kisako Shikano, Katsuya Yamada, Satoshi Ono, Minami Hoki, Fumiya Ishizuka, Soichiro Hagio, Chiaki Takeshita, Hisayoshi Omori, Kiyohiro Hashimoto, Satsuki Chikura, Masamitsu Honma, Kei-ichi Sugiyama, Masayuki Mishima

“…Moreover, ddE, a relative-energy based index derived from quantum chemistry calculations that measures the stability nitrenium ions, has been correlated with mutagenicity. This study aims to further examine the ability of the ddE-based approach in improving QSAR mutagenicity predictions for PAAs and to develop a refined method to decrease false positive predictions. …”
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In silico and in vivo evaluations of fisetin and fisetin-loaded nanosuspension on monoamine oxidase inhibition in Aβ(25–35) induced dementia in mice model by Siti Zaidathul Iman Zolkiffly, Mizaton Hazizul Hasan, Siti Azma Jusoh, Ashok Kumar Janakiraman, Sathesh Kumar Sukumaran, Noreen Husain, Yuslina Zakaria, Hanish Singh Jayasingh Chellammal

“…Conclusion: Fisetin with optimized bioavailability, effectively exhibits neuroprotection through molecular interactions of MAO enzymes. …”
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Age-specific protective effects of statins against cirrhosis in patients with chronic liver enzyme elevation associated with metabolic dysfunction: a retrospective cohort study of... by Ayako Suzuki, Georgia Sofia Karachaliou, Amy M. Perkins, Chad Dorn, Ruth M. Reeves, Timothy Arnold, Mustafa R. Bashir, Jimmy T. Efird, Manal F. Abdelmalek, Anna Mae Diehl

“…Summary: Background: The hepatoprotective effects of statins in chronic liver diseases are well-documented; however, variation by age, sex, and formulation remains unclear. The optimal regimen for cirrhosis prevention has yet to be defined. …”
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Pretreatment CT-based machine learning radiomics model predicts response in unresectable hepatocellular carcinoma treated with lenvatinib plus PD-1 inhibitors and interventional th... by Haihong Zhu, Xuan Luo, Zhixian Sun, Yonglin Hua, Yuxin Xiao, Huilong Li, Xiaowu Ma, Wenliang Tan, Zhiqin Xie, Ziyu Zhang, Chenwei Tang, Hongkai Zhuang, Weikai Xu, Yajin Chen, Changzhen Shang

“…Nine machine learning classifiers were tested and the multilayer perceptron classifier with optimal performance was used as the radiomics model. …”
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