Identification of depression and anxiety during pregnancy: A systematic review and meta‐analysis of test accuracy by Elisabet Rondung, Pamela Massoudi, Katri Nieminen, Birgitta Wickberg, Nathalie Peira, Rebecca Silverstein, Klas Moberg, Martina Lundqvist, Åke Grundberg, Monica Hultcrantz

“…Ten of the EPDS articles provided data for synthesis at cutoffs ≥10 to ≥14 for diagnosing major depressive disorder. Cutoff ≥10 gave the optimal combined sensitivity (0.84, 95% confidence interval [CI]: 0.75–0.90) and specificity (0.87, 95% CI: 0.79–0.92). …”
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DYNAMICS OF PROAND ANTI-INFLAMMATORY PROSTAGLANDINS IN CASES OF GENERALIZED PERIODONTITIS ACCOMPANIED BY DIFFERENT TYPES OF REACTIVITY OF THE BODY by Yu.Yu. Yarov, Yu.I. Silenko

“…Correction of altered parameters in patients with generalized periodontitis with impaired (hyperand hyporeactivity) of the body with bringing them to values, typical for normoreactivity is considered to be a condition for optimizing the healing of mucosal wounds after surgery and further stabilization of the process in periodontal tissues. …”
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ANTIMICROBIAL ACTIVITY OF WATER-ETHANOLIC EXTRACTIONS FROM QUERCUS ROBUR L. LEAVES AND BUDS by N. A. Ryabov, V. M. Ryzhov, V. A. Kurkin, S. D. Kolpakova, A. V. Zhestkov, A. V. Lyamin

“…Quercus robur L. is a promising plant object, medicinal plant raw materials of which can be used for the development of new antimicrobial drugs.The aim of the study is screening of the antimicrobial activity of water-ethanolic extractions from Quercus robur L leaves and buds.Materials and methods. …”
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Effects of sleep deprivation on heart rate variability: a systematic review and meta-analysis by Suling Zhang, Xiaodan Niu, Jinke Ma, Jinke Ma, Xin Wei, Xin Wei, Jun Zhang, Jun Zhang, Weiping Du

“…However, existing studies exhibit considerable heterogeneity due to inconsistencies in HRV measurement methods, variations in deprivation duration, and inadequate control of confounding factors.ObjectiveThis study aimed to comprehensively evaluate the impact of sleep deprivation on HRV through a systematic review and meta-analysis of randomized controlled trials (RCTs), to elucidate the potential mechanisms underlying sleep deprivation-induced cardiac autonomic dysfunction, and to provide insights for optimizing sleep-related interventions and preventing cardiovascular disease.MethodsA systematic search was conducted in PubMed, Embase, CNKI, Wanfang, and VIP databases for RCTs investigating the effects of sleep deprivation on HRV, covering the period from January 2010 to May 2024. …”
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Material Sustainability Information Disclosure and Company Performance: The Moderating Role of Business Strategy by Mehrdad Panahi Dorcheh, Hamzeh Didar, Gholamreza Mansourfar, Mehdi Heydari, Ali Ashtab

“…Therefore, this study aims to investigate the influence of material sustainability information disclosure on company performance, while also considering the moderating effect of business strategy. …”
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ED50 and ED95 of hypobaric ropivacaine during unilateral spinal anesthesia in older patients undergoing hip replacement surgery by Chao Lin, Chao Lin, Wen-Lin Xian, Jun Xu, Ting Zhao, Zhi-Qiang Wu, Fang-Jun Wang

“…ObjectiveThe spinal block was limited to the operative side during unilateral spinal anesthesia, which has less physiological interference and fewer complications for the patient. The optimal dose of ropivacaine for unilateral spinal anesthesia is still unclear. …”
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Unveiling the Spectrum of Nosocomial Candiduria: A Cross-Sectional Analysis in a Tertiary Care Hospital of Punjab, Pakistan by Syed Fatima Nadeem, Muhammad Shahbaz Hussain, Farhan Rasheed, Israr Ahmad, Syed Sohail Ahmad

“…With increasing resistance in non-albicans Candida species, early and accurate diagnosis is a must for optimal management. This study recommends targeted antifungal therapy and regular surveillance to combat the growing problem of candiduria in hospitals. …”
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Supporting Physical and Mental Health in Rural Veterans Living With Heart Failure: Protocol for a Nurse-Led Telephone Intervention Study by Lucinda J Graven, Laurie Abbott, Josef V Hodgkins, Thomas Ledermann, M Bryant Howren

“…Managing HF in the home is stressful and complex for rural veterans who experience unique barriers to optimal physical and mental health, necessitating adequate support and problem-solving skills. …”
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Research progress and application prospect of hydrogen storage technology in underground space by Mincong WANG, Lei HOU, Xueting WANG, Muqingyun YANG, Zicong XU, Yueqi LIU, Shuyan ZHU

“…Considering foreign experience of underground hydrogen storage and the identified risks and challenges, salt caverns can be regarded as the most mature and optimal option for underground hydrogen storage available today. …”
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Cross-evaluation of wearable data for use in Parkinson’s disease research: a free-living observational study on Empatica E4, Fitbit Sense, and Oura by Haakon Reithe, Brice Marty, Juan C. Torrado, Elise Førsund, Bettina S. Husebo, Ane Erdal, Simon U. Kverneng, Erika Sheard, Charalampos Tzoulis, Monica Patrascu

“…The three analyzed devices are not interchangeable and, based on data features, none were deemed optimal for PD research, but they all have the potential to provide suitable specifications in future iterations.…”
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Artemether-lumefantrine dosing for malaria treatment in young children and pregnant women: A pharmacokinetic-pharmacodynamic meta-analysis. by Frank Kloprogge, Lesley Workman, Steffen Borrmann, Mamadou Tékété, Gilbert Lefèvre, Kamal Hamed, Patrice Piola, Johan Ursing, Poul Erik Kofoed, Andreas Mårtensson, Billy Ngasala, Anders Björkman, Michael Ashton, Sofia Friberg Hietala, Francesca Aweeka, Sunil Parikh, Leah Mwai, Timothy M E Davis, Harin Karunajeewa, Sam Salman, Francesco Checchi, Carole Fogg, Paul N Newton, Mayfong Mayxay, Philippe Deloron, Jean François Faucher, François Nosten, Elizabeth A Ashley, Rose McGready, Michele van Vugt, Stephane Proux, Ric N Price, Juntra Karbwang, Farkad Ezzet, Rajesh Bakshi, Kasia Stepniewska, Nicholas J White, Philippe J Guerin, Karen I Barnes, Joel Tarning

“…Relatively lower cure rates and lumefantrine levels have been reported in young children and in pregnant women during their second and third trimester. The aim of this study was to investigate the pharmacokinetic and pharmacodynamic properties of lumefantrine and the pharmacokinetic properties of its metabolite, desbutyl-lumefantrine, in order to inform optimal dosing regimens in all patient populations.…”
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Future Site Suitability for Urban Waste Management in English Bazar and Old Malda Municipalities, West Bengal: A Geospatial and Machine Learning Approach by Suresh Mondal, Mst Tania Parveen, Asraful Alam, Rukhsana, Nazrul Islam, Beata Calka, Bashar Bashir, Mohamed Zhran

“…The findings provide crucial insights for urban planners and decision-makers, facilitating the identification of optimal locations for sustainable waste management in urban settings.…”
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HPLC-MS/MS method development and validation for the determination of tetradecapeptide in human plasma by M. A. Tokareva, E. S. Melnikov, M. V. Belova, E. N. Fisher, T. A. Rodina, I. E. Shohin

“…Peptide derivatization can help achieve optimal chromatographic separation and increase method sensitivity.Aim. …”
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Post-training breakdown: acute effects of different training types on body hydration status and performance by Erkan Demirkan, Mehmet İsmail Tosun, Abdurrahim Kaplan, Mert Ayrancı, Damian George Cosmin, Mustafa Arıcı, Mehmet Kutlu, Veysi Aslan, Michael Favre

“…Implementing enhanced hydration strategies during endurance-focused sessions may also help mitigate these acute impacts and optimize recovery and performance in young wrestlers.…”
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Review and Study of Water Mills in Darreh Shahr City by Akbar Sharifinia

“…Water availability and its usage could be regarded as one of the factors influencing the sustainability of the civilizations. Optimal use of water in the old water networks and the other associated installations indicates the sufficient knowledge of their creators about the principles and science of water. …”
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The published role of artificial intelligence in drug discovery and development: a bibliometric and social network analysis from 1990 to 2023 by Murat Koçak, Zafer Akçalı

“…Therefore, this study aims to systematically analyze the scientific literature on the application of AI in drug discovery and development to understand the evolution, trends, and key contributors within this rapidly growing field. …”
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Effectiveness of systemic treatments for advanced non-clear cell renal cell carcinoma: a systematic review and meta-analysis by Yaping Zhang, Jian Chen, Xiaoyan Wang, Hui Wang, Xiaoli Chen, Jianfeng Hong, Hongming Fang

“…BackgroundNon-clear cell renal cell carcinoma (nccRCC) represents a heterogeneous group of malignancies with substantial differences in morphology, genetic profiles, clinical behavior, and prognosis. Optimal treatment for nccRCC remains unclear, largely extrapolated from evidence available for clear cell renal cell carcinoma (ccRCC). …”
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Effect of planting geometry and chemical fertilizers on growth characteristics, essential oil yield and composition of Inula racemosa under cold desert conditions of western Himala... by Sakshi Vishvamitera, Sidharth Baghla, Varun Parmar, Romika Thakur, Sanatsujat Singh, Sachin Vashisath, Dinesh Kumar, Satbeer Singh, Ramesh Chauhan

“…Similarly, appropriate plant orientation significantly contributes to utilizing natural resources efficiently, leading to higher yields. Therefore, the study aimed to optimize the fertilizer dose for I. racemosa with a suitable planting geometry. …”
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Development of a Clinical Framework–Anastomotic Leakage Prediction Score (CF–ALPS) After Colorectal Surgery by Fırat Mülküt, Cem Batuhan Ofluoğlu

“…A cutoff score ≥7 demonstrated optimal risk stratification, classifying patients into high- and low-risk groups with a positive predictive value (PPV) of 72.0% and a negative predictive value (NPV) of 88.0%. …”
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Using Machine Learning Approaches on Dynamic Patient-Reported Outcomes to Cluster Cancer Treatment-Related Symptoms by Nora Asper, Hans Friedrich Witschel, Louise von Stockar, Emanuele Laurenzi, Hans Christian Kolberg, Marcus Vetter, Sven Roth, Gerd Kullak-Ublick, Andreas Trojan

“…In patients undergoing systemic treatment for cancer, symptom tracking via electronic patient-reported outcomes (ePROs) has been used to optimize communication and monitoring, and facilitate the early detection of adverse effects and to compare the side effects of similar drugs. …”
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