Exploring the Willingness of Young and Middle-Aged CHD Patients to Participate in Home-Based Cardiac Rehabilitation: A Qualitative Study by Liu T, Yang S, Rong S, Liu M, Wang X, Ji Y

“…In-depth understanding of the subjective perception and willingness to participate in HBCR of patients with CHD is crucial to the precise formulation of rehabilitation programs and the promotion of the clinical application of HBCR. The aim of this study was to explore the factors influencing young and middle-aged CHD patients’ willingness to participate in HBCR.Patients and Methods: This study used the qualitative descriptive approach. …”
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HEALTH METHODOLOGY FOR REDUCING ANXIETY AND SUPPORTING THE FUNCTIONAL HEALTH OF CHILDREN by Shuba Liudmyla, Shuba Victoria, Shuba Victor

“…The purpose of the study – to develop the methodology of using health-improving exercises aimed at reducing the level of anxiety and maintaining the optimal level of the functional state for primary school children during a full-fledged war. …”
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Comparative cardiomyocyte differentiation potential of rat adipose-derived mesenchymal stem cells from two anatomical sites: metabolomic profiling and pathway analysis by Ahmed Farag, Ahmed Farag, Haney Samir, Sai Koung Ngeun, Masahiro Kaneda, Hanan Hendawy, Ken Takahashi, Ryou Tanaka

“…Such insights are critical for optimizing stem cell-based therapies for cardiac regeneration. …”
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Digital Physical Activity and Sedentary Behavior Interventions for Community-Living Adults: Umbrella Review by Eilidh Russell, Alison Kirk, Mark D Dunlop, William Hodgson, Mhairi Patience, Kieren Egan

“…ObjectiveThis umbrella review aimed to explore digital PA and SB interventions for community-living adults across effectiveness, key components, and methodological quality. …”
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Contradictions of judicial criminal policy by Yu. E. Pudovochkin, M. M. Babayev

“…The subject of the study is the criminal policy in the context of contradictions in the functioning of the courts.The purpose of the study is to investigate, which contradictions of criminal policy are generated by a multi-level system of courts, and which mechanisms for overcoming them in order to optimize criminal policy could be found out.The methodology. …”
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European Union: From social integration to social state by Brkić Luka

“…Redistribution across countries could also considerably change the optimal rate of tariff. The EU with its regional cohesion funds might be a good example of how those are used as a side-payment for diminishing the social divergence in the member countries. …”
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Correlation between Serum Levels of Some Immunological Biomarkers and Severity of Idiopathic Immune Thrombocytopenia by Ola A. Hashim, Rawaa N. Alchalabi, Bassam F. Matti, Yaseen I. Mamoori

“…ROC analysis demonstrated exceptional diagnostic performance for CD28, CTLA4, FoxO3, and IL-39, with AUC values of 1.0 in ND patients, achieving 100% sensitivity and specificity at optimal cut-off points. TNFAIP3 showed excellent discriminatory power in ND patients (AUC = 1.0), but limited diagnostic value in MD cases (AUC = 0.537). …”
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Dose-Dependent Cellular Phenotypic Change Induced by ¹⁷⁷Lu-Oxodotreotide Treatment in IMR-32 Cells by Shuai Xue, Xiaobei Zheng, Bingbing Pu, Xiao Li, Jun Li, Meng Huang, Jian Yang, Jingjing Lou

“…These findings underscore the necessity of optimizing dosing regimens to balance therapeutic efficacy and safety in clinical settings, providing a foundation for personalized β-emitter therapies.…”
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Integrated transcriptomic and metabolomic analyses reveal tissue-specific accumulation and expression patterns of monoterpene glycosides, gallaglycosides, and flavonoids in Paeonia... by Pan Xu, Jinghui Li, Cuiting Chen, Jing Chen, Meiping Yang, Huimin Deng, Xuechun Jiang, Kelang Lou, Xiaojun Wu, Rubing Chen, Yijuan Hu, Weiqing Liang, Jinbao Pu

“…The study provides a valuable theoretical foundation for future metabolic engineering aimed at optimizing the biosynthetic pathways of these primary active constituents in PL.…”
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The association between the American heart association’s new “Life’s Essential 8” and different types of arthritis: insights from a large population study by Erkai Pang, Xuxu Chen, Yu Zhu, Litian Shi, Tao Wang, Yuanbin Kou, Wei Wang, Jin Li, Hui Kang

“…Abstract Previous research has demonstrated an inverse relationship between optimal cardiovascular health (CVH) and the prevalence of osteoarthritis (OA). …”
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Analysis of treatment patterns and persistence on branded and generic medications in major depressive disorder using retrospective claims data by Solem CT, Shelbaya A, Wan Y, Deshpande CG, Alvir J, Pappadopulos E

“…., Global Health Outcomes, New York, NY, 3Epidemiology Department of Mailman’s School of Public Health, Columbia University Mailman School of Public Health, New York, NY, USA Background: In major depressive disorder (MDD), treatment persistence is critical to optimize symptom remission, functional recovery, and health care costs. …”
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Predictive Value of Varicocele Grade and Histopathology in Simultaneous Varicocelectomy and Sperm Retrieval in Non-Obstructive Azoospermia: A Retrospective Cohort Study by Aris Kaltsas, Fotios Dimitriadis, Michael Chrisofos, Nikolaos Sofikitis, Athanasios Zachariou

“…These findings provide valuable insights for optimizing fertility treatments in men with NOA undergoing varicocele repair.…”
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Novel Classification of Peroneal Tendon Disease Reveals Cellular and Molecular Phenotypes of the Tenosvnovium by Julia Matthias MD, Michael A. David PhD, Sara E. Buckley DO, Daniel J. Ross MD, Nathaniel Zona BA, Michael A. Hewitt B.A., Joshua Metzl MD, Daniel K. Moon MD, MS, MBA, Courtney Grimsrud MD, Douglas J. Adams PhD, Michael Zuscik PhD, Kenneth Hunt MD

“…Improved clarity in biological pathways and cellular characterization of the tenosynovium in each classification of PTD will help optimize surgical strategies and allow for personalized therapeutic intervention for PTD.…”
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Use of glycoprotein IIb/IIIa inhibitors in myocardial infarction in the Russian Federation, according to the Russian Registry of Acute Myocardial Infarction REGION-IM by N. S. Kostritca, R. M. Rabinovich, R. M. Shakhnovich, I. S. Yavelov, R. G. Gulyan, Yu. K. Rytova, S. N. Tereschenko, A. D. Erlikh, D. V. Pevzner

“…Aim. To analyze the frequency, indications, and outcomes of using glycoprotein IIb/IIIa inhibitors in patients with acute myocardial infarction (AMI) in Russia based on data from a multicenter registry.Material and methods. …”
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Comparative efficacy and safety of drug-coated balloons versus drug-eluting stents in small vessel coronary artery disease: an updated systematic review and meta-analysis of random... by Monisha Augustine, Mustafa Arain, Muhammad Saqlain Mustafa, Iman Moradi, Matthew Fredericks, Aaliya Rahman, Muhammad Afnan Ashraf, Glawish Sualeh, Rubab khan, Aqsa Saif, Haifa Arain, Dilip Baldevsingh Rajpurohit, Abdalkareem Nael Jameel Maslamani, Behrooz Shojai Rahnama, Javed Iqbal

“…Drug-coated balloons (DCBs) offer a potential alternative, but their efficacy compared to drug-eluting stents (DES) remains debated. This meta-analysis aims to provide updated insights into the comparative outcomes of DCBs versus DES in small coronary artery disease. …”
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Pre-Exercise Ingestion of Hydrogen-Rich Cold Water Enhances Endurance Performance and Lactate Response in Heat by Mariem Khlifi, Nidhal Jebabli, Nejmeddine Ouerghi, Fatma Hilal Yagin, Ashit Kumar Dutta, Reem Alwhaibi, Anissa Bouassida

“…To enhance heat loss and optimize athletic performance, pre-cooling interventions can be employed to accelerate body cooling. …”
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The clinical analysis and indications for exchange transfusion in 158 children with pertussis characterized by marked leukocytosis by Gaihuan Zheng, Qing Liu, Chuan Gan

“…Abstract Background Hyperleukocytosis (WBC ≥ 30 × 10⁹/L) strongly associated with fatal outcomes; evidence-based thresholds for initiating exchange transfusion (ET) remain undefined. This study aims to investigate the association between leukocyte elevation and disease severity, and define evidence-based thresholds for initiating exchange transfusion, to assist clinical doctors in determining evidence-based medical indications for ET therapy in pediatric patients with pertussis exhibiting marked leukocytosis (WBC ≥ 30 × 10⁹/L). …”
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Diurnal variations in gait parameters among older adults with early-stage knee osteoarthritis: insights from wearable sensor technology by Anuradhi Bandara, Hiroki Shimizu, Daiki Watanabe, Toyota Misa, Shota Suzuki, Kyoma Tanigawa, Momoko Nagai-Tanima, Tomoki Aoyama

“…Understanding its impact on gait dynamics throughout the day is crucial for optimizing management strategies. This study aimed to explore diurnal variations in gait parameters among older adults with KOA using an in-shoe motion sensor (IMS) system equipped with accelerometers and gyroscopes. …”
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Distinct Roles of HHLA2 and PD-L1 in the Immune Cell and Prognosis of Hepatocellular Carcinoma by Wang CH, Chen SL, Yang X, Wu T, Liu LL, Yun JP

“…The combined assessment of HHLA2 and PD-L1 expression facilitates risk stratification, providing a framework to optimize immunotherapy strategies. These findings contribute to the advancement of precision medicine in the management of HCC.Keywords: HHLA2, PD-L1, TILs, prognosis, HCC…”
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Presenting a Leadership Empowerment Model through Sense-making by Using the Cognitive and Behavioral Scripts by Hamid Zare, Aliasghar Pourezzat, Hasan Zareei Matin, Arezoo Salmani

“…This research initiative was undertaken with the aim of exploring how the sense-making process can significantly enhance leadership capabilities through the systematic deployment of behavioral scripts and cognitive scripts. …”
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