Evaluating the Opioid-Related Adverse Events of Oliceridine Versus Conventional Opioids in Patient-Controlled Analgesia After Thoracoscopic Lung Resection: A Retrospective Cohort S... by Huang C, Liu B, Xie S, Zhang Y, Liu K, Qiu Y, Wu J

“…However, the comparative incidence of opioid-related adverse events (ORADEs) in patient-controlled intravenous analgesia (PCIA) remains understudied. This study aims to elucidate the differences in ORADE rates between oliceridine and conventional opioids in PCIA.Methods: We conducted a population-based retrospective cohort study at Shanghai Chest Hospital, analyzing linked healthcare data. …”
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Comparative Analysis of Corneal Wound Healing: Differential Molecular Responses in Tears Following PRK, FS-LASIK, and SMILE Procedures by Dominika Janiszewska-Bil, Beniamin Oskar Grabarek, Anita Lyssek-Boroń, Aleksandra Kiełbasińska, Bernadeta Kuraszewska, Edward Wylęgała, Katarzyna Krysik

“…Background/Objectives: In this study, we aimed to analyze the changes in the expression profiles of selected messenger RNAs (mRNAs) and their encoded proteins in the tears of patients undergoing photorefractive keratectomy (PRK), femtosecond-assisted laser in situ keratomileusis (FS-LASIK), and small-incision lenticule extraction (SMILE) procedures. …”
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Lower 1-Year PROM Completion Rates and Need for Intensive Follow-Up in Inpatient Medicare THA Patients: Implications for the CMS PROM Policy by Khaled A. Elmenawi, MD, Ignacio Pasqualini, MD, Shujaa T. Khan, MD, Chao Zhang, MS, Matthew E. Deren, MD, Nicolas S. Piuzzi, MD, Cleveland Clinic Adult Reconstruction Research Group, Kurt P. Spindler, MD, Trevor G. Murray, MD, Robert M. Molloy, MD, Kim L. Stearns, MD, Viktor E. Krebs, MD, Nicholas R. Scarcella, MD, Michael Erossy, MD, Alexander L. Roth, MD, Michael R. Bloomfield, MD, Carlos A. Higuera, MD, John P. McLaughlin, DO, Peter A. Surace, MD

“…However, evidence is lacking in identifying patients who fail to respond to PROM collection efforts. This study aimed to (1) evaluate rates of successful PROM collection between inpatient and outpatient Medicare total hip arthroplasty (THA) patients and (2) identify patient-specific factors associated with active follow-up to obtain 1-year PROMs. …”
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Remote Monitoring of Chemotherapy-Induced Peripheral Neuropathy by the NeuroDetect iOS App: Observational Cohort Study of Patients With Cancer by Ciao-Sin Chen, Michael P Dorsch, Sarah Alsomairy, Jennifer J Griggs, Reshma Jagsi, Michael Sabel, Amro Stino, Brian Callaghan, Daniel L Hertz

“…ObjectiveThis prospective, longitudinal observational cohort study aimed to determine the feasibility and accuracy of app-based remote monitoring of CIPN in patients with cancer undergoing neurotoxic chemotherapeutic treatment and to conduct exploratory comparisons of app-based functional CIPN monitoring versus patient-reported outcome–only monitoring. …”
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Home-Based Intervention Tool for Cardiac Telerehabilitation: Protocol for a Controlled Trial by Francesca Mastorci, Maria Francesca Lodovica Lazzeri, Lamia Ait-Ali, Paolo Marcheschi, Paola Quadrelli, Massimiliano Mariani, Rafik Margaryan, Wanda Pennè, Marco Savino, Giuseppe Prencipe, Alina Sirbu, Paolo Ferragina, Corrado Priami, Alessandro Tommasi, Cesare Zavattari, Pierluigi Festa, Stefano Dalmiani, Alessandro Pingitore

“…As a branch of telehealth, CR can be optimized and facilitated using remote telemedicine devices. …”
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Evaluating the potential of graphene oxide to promote skeletal muscle complex regeneration by Yulu Chen, Zeyu Zhu, Yian Shen, Xuling Liu, Yushi He, Chengqi Lyu, Jiayu Lu

“…BackgroundRepair and regeneration of the musculoskeletal system are critical for maintaining mobility, physical function, and overall quality of life. This study aimed to optimize the size and concentration of graphene oxide (GO) to achieve a balance that enhances the proliferation and myogenic differentiation of C2C12 cells and investigate the underlying mechanisms, including the activation of key myogenic genes and signaling pathways. …”
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Comparison of efficacy and prognostic impact of adjuvant 131I therapy at 3.7 GBq and 5.55 GBq in DTC patients with unexplained sTg elevation by Nan Sun, Mengyue Liu, Chuang Xi, Quanyong Luo, Xiaoer Wei, Zhongling Qiu

“…Abstract Background The optimal dose of adjuvant radioiodine(131I) therapy for differentiated thyroid cancer (DTC) remains controversial. …”
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Effectiveness of clindamycin-based exposure strategies in experimental mature staphylococcal biofilms by S. C. J. van Dun, M. Verheul, B. G. C. W. Pijls, H. Scheper, A. M. van der Does, P. H. Nibbering, M. G. J. de Boer

“…ABSTRACT Due to increasing antimicrobial resistance and side effects caused by current standard antimicrobial regimens used for treatment of prosthetic joint infection (PJI), alternative options are urgently needed. We aimed to investigate the effect of clindamycin in different exposure strategies against Staphylococcus aureus in an in vitro mature biofilm model. …”
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Comparative assessment of biocompatibility of various fluoride agents in cell culture by Bengi Aydınel, Çağla Kayabaşı, Dilşah Çoğulu, Cumhur Gündüz

“…Abstract Objective This study aimed to evaluate the biocompatibility of various fluoride agents using L929 fibroblast and human gingival fibroblast (HGF) cell cultures. …”
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Potential categories of perceived recurrence risk in stroke patients and their relationship with self-management ability by Yihao Wu, Shitong Gong, Fei Long, Jie Yin

“…ObjectiveThis study aimed to identify latent profile categories of recurrence risk perception among stroke patients, analyze the factors influencing these categories, and examine their correlation with self-management ability. …”
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Lercanidipine in patients with chronic renal failure: the ZAFRA Study by N. R. Robles, J. Ocon, C. F. Gomez, M. Manjon, L. Pastor, J. Herrera, J. Villatoro, J. Calls, J. Torrijos, V. I. Rodríguez, M. M. A. Rodriguez, M. L. Mendez, A. Morey, F. I. Martinez, J. Marco, A. Liebana, B. Rincon, F. Tornero

“…Aim. To evaluate the safe use of a new calcium channel blocker, lercanidipine, in patients with chronic renal failure (CRF); the protective effect of calcium channel blocker on renal function in CRF patients previously treated with ACE inhibitors or angiotensin receptor blockers (ARB). …”
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L'Aprenentatge virtual com a una nova forma d'ensenyar i d'aprendre a través de les tecnologies de la informació i la comunicació by Elisenda López Fernández, Olatz López Fernández

“…Therefore, as it is observed in this article, the new research trends are aimed at two kinds of study: to optimize the e-learning system design and to analyze the distinctive aspects of elearners. …”
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Impact of Supercritical Carbon Dioxide on Pore Structure and Gas Transport in Bituminous Coal: An Integrated Experiment and Simulation by Kui Dong, Zhiyu Niu, Shaoqi Kong, Bingyi Jia

“…Understanding these changes is crucial for optimizing CH₄ extraction and improving CO₂ sequestration efficiency. …”
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Metabolic Profile Correction in Patients with Obstructive Sleep Apnea Depends on the Duration of CPAP Therapy Sessions by M. V. Gorbunova, S. L. Babak, O. Yu. Rebrova, M. A. Karnaushkina, A. G. Malyavin

“…However, the effects of long-term CPAP therapy with night sessions > 6 hours remain poorly understood. The aim of the study was to study the effects of different durations of night sessions of CPAP therapy on the “metabolic profile” of patients with severe OSA. …”
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Comparative evaluation of empagliflozin, canagliflozin and sitagliptin cardioprotective properties in rats with experimental type 2 diabetes mellitus by A. V. Simanenkova, S. M. Minasian, T. L. Karonova, T. D. Vlasov, N. V. Timkina, А. K. Khalzova, O. S. Fuks, A. A. Shimshilashvili, V. A. Timofeeva, Yu. Yu. Borshchev, M. M. Galagudza

“…Background: Myocardial infarction (MI) is one of the leading causes of mortality in patients with type 2 diabetes mellitus (DM), therefore it is essential to give preference to a glucose-lowering drug having optimal cardioprotective properties. A comparative study of the various sodium-glucose co-transporter inhibitors representatives’ protective effects in experimental MI was not carried out within the framework of one study.Aim: To evaluate the influence of empagliflozin (EMPA) and canagliflozin (CANA), in comparison with sitagliptin (SITA), on hemodynamic parameters and myocardial damage area in rats with diabetes type 2 model in experimental MI.Materials and methods: Type 2 DM was modelled in Wistar rats by means of 4-week high-fat diet followed by nicotinamide 230 mg/kg and streptozotocin 60 mg/kg administration. 4 weeks after DM induction the following groups were made: «DM+SITA» — treatment with SITA 50 mg/kg, «DM+EMPA» — treatment with EMPA 2 mg/kg, «DM+CANA» — treatment with CANA 25 mg/kg per os once daily for 8 weeks. …”
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Surgical treatment of patients with cerebral metastases in the motor area by D. M. Belov, V. B. Karakhan, A. Кh. Bekyashev, N. V. Sevyan, V. A. Aleshin, A. A. Mitrofanov, E. V. Prozorenko, D. V. Sashin, N. V. Garanina

“…In general, all efforts during surgical intervention should be aimed at restoring a good functional status, since severe neurological symptoms can deprive patients of the opportunity to continue complex treatment, which will negatively affect overall survival. …”
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Relationship between Lower Limb Flexibility, Power, Agility and Speed in Football Players: A Cross-sectional Study by Tresha Parmar, Neha Mukkamala

“…Aim: To examine the relationship between lower limb flexibility, power, agility, and speed in football players. …”
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An e-Learning Intervention for Professionals to Promote Family-Centered Cancer Care When a Significant Caregiver for Children Is at End of Life: Mixed Methods Evaluation Study by Cherith Jane Semple, Carla O'Neill, Sarah Sheehan, Tanya McCance, Amanda Drury, Jeffrey R Hanna

“…ConclusionsThe systematic and iterative person-based approach optimized the acceptability of a novel e-learning intervention, having the potential to promote family-centered supportive end-of-life cancer care. …”
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Development of fi lm forming formulation and technology of polymeric fi lm coating on Indotril tablets by L. I. Kucherenko

“…Received tablet cores should be covered by protective polymeric film with the purpose of unpleasant taste elimination, increase of tablets expiration date. Objective. The aim of our investigation was to develop the film forming composition and technology of polymeric film coating on «Indotril» tablets in pseudo-fluidized layer. …”
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Ultrasound-assisted green synthesis of silver nanoparticles using Ruta graveolens L. Extract and antitumor evaluation by Nikita Gandlevskiy, Altevir Rossato Viana, Gabriel Toneto Druzian, Daiana Kaminski Oliveira, Andre Passaglia Schuch, Alessandro Barge, Giancarlo Cravotto, Erico Marlon Moraes Flores

“…This study aims to evaluate the ultrasound-assisted synthesis of silver nanoparticles (AgNPs) based on an aqueous extract of Ruta graveolens L. to reduce Ag+ to Ag0. …”
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