Evaluation of continued 2-monthly or annual urate monitoring in gout: an extension of the GoutSMART randomised controlled feasibility trial by Philip L. Riches, Debbie Alexander, Clare Brown, Hawazin Abbas, Rowan Hart, Amrey Krause

“…Aim: Improved outcomes for patients with gout are associated with reduced urate levels and many guidelines recommend regular urate monitoring. …”
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Non-adherence to medication and its associations among type 2 diabetes patients following up with health coaches in primary healthcare centers, Makkah city, KSA by Ahmad Salah Alkathiri, Renad Turki Alghamdi, Abeer Ahmad Alamri, Haneen Hassan Alhazmi, Sarah Badr Alsharif, Sahab Muqbil Alharbi, Muath Aldomini, Baraa Sami Quronfulah, Mohamed O. Nour, Mohamed Osman Elamin, Abdullah Khalid Alafif, Saud Hasan Surbaya, Osama M. Hayat Noor

“…Understanding the factors contributing to non-adherence is crucial for developing effective interventions and improving patient care. Aim This study aimed to assess medication non-adherence among T2DM patients following up with health coaches in primary healthcare centers (PHCCs) in Makkah City and identify associated factors influencing adherence levels. …”
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Students’ Mastering of Structural Analysis of Substance as a Method to Form Future Specialists’ Scientific Thinking. Part II by L. A. Baikova, M. A. Kosareva, E. A. Nikonenko, V. V. Vaitner, A. Majee

“…The acquired competencies are the key to professional literacy, which is improved in master’s degree programme, when the previously compactified scientific knowledge in a contracted form is developed in the form suitable for an optimal solution of a particular research or practical aim. …”
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THE ROLE OF THE HUMANITIES AND SOCIAL SCIENCES IN HIGHER EDUCATION: INTERNATIONAL EXPERIENCE by N. Kliuchkovska

“…This experience demonstrates that optimizing the Social Sciences and Humanities in the European and American higher education exists to up-to-date their content on the basis of modern science; introduce new disciplines oriented to improve personal qualities; use innovative technologies, innovative methods and forms of education; introduce colloquial disciplines – public speaking, discussion in small groups, with the aim to develop critical analysis. …”
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Relationship between Patterned Grounds Evolutions and Spatial and Temporal Changes in the Chemical Compounds of SAHL ABAD Playa Salt Flats (Case Study: Khorasan province) by Mahdi Saghafi

“…In this study, percent changes in some of the chemical compounds such as sodium chloride, sodium and gypsum in the playa were calculated with the aim of satellite data for two periods. Besides, using texture and pattern analysis of the PCA1, percent changes in the surface pattern grounds of the playa was calculated. …”
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Machine learning based screening of biomarkers associated with cell death and immunosuppression of multiple life stages sepsis populations by Jie Yang, Fanyan Ou, Binbin Li, Lixiong Zeng, Qiuli Chen, Houyu Gan, Jianing Yu, Qian Guo, Jihua Feng, Jianfeng Zhang

“…Within the framework of computational biology and machine learning strategies, and against the backdrop of global multicenter sepsis cohort data, this study aims to deeply mine and screen specific biomarkers related to the immune microenvironment and programmed cell death in populations across different life stages (neonates, children, and adults). …”
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Evaluation of SSM-Wheat Model in Simulating the Growth and Development of Wheat (Triticum aestivum L.) Cultivars in Different Planting Densities by Ali Rahemi karizki, Faramarz Sayyedi, Habib allah Soghi, Arazqlych Marfy, Mojtaba Salehi SHaikhi, Saeed Bagherikia

“…Changing the density towards an optimal density can alter the ratio of soil evaporation to plant transpiration in such a way that water use efficiency improves. …”
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Geographical Spatial Pattern and Spatiotemporal Suitability Evolution of Cultural Heritage in the Liao River Basin by Jingcheng YUAN, Bijiao LI, Sifan QIU

“…Multivariate regression and path analysis are used to quantify the effects of climatic and institution on the heritage evolution .Results 1) Distribution determinants: The majority of heritage sites (95.2%) are located in optimal environmental conditions: elevation: below 500 m (mean value: 217.3±134.8 m); slope: less than 6° (84.7% ranging from 0° to 3°); distance to river: within 7 km. …”
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Right ventricular strain predicts outcome in patients receiving sacubitril/valsartan: A sub‐analysis of DISCOVER‐ARNI by Maria Concetta Pastore, Giulia Elena Mandoli, Alberto Giannoni, Francesca Rubina Ginetti, Michele Correale, Natale Daniele Brunetti, Andrea Igoren Guaricci, Laura Piscitelli, Anna Degiovanni, Giuseppe Patti, Alessandro Malagoli, Luca Moderato, Erberto Carluccio, Paolo N. Marino, Michele Emdin, Matteo Cameli

“…Abstract Aims Angiotensin receptor/neprilysin inhibitors (ARNI) have emerged as a pivotal medical treatment considerably improving the clinical outcome of patients with heart failure and reduced ejection fraction (HFrEF). …”
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Feasibility Study of Low- input Pistachio Production: Case Study of Dasht-e-Rabat Region- Shahr-e-Babak County by Farangissadat Hosseini Dana, Mehdi Nooripoor

“…However, on the other hand, given the nature of organic farming with emphasis on no use of chemicals in the production process, it is a bit difficult to reach, so one of the recent approaches that has been considered to protect the environment, especially in the field of agriculture, is the production of healthier goods with low usages of external inputs. Thus, the aim of this study was to investigate the feasibility of producing low-input pistachio in Dasht-e-Rabat region of Shahr-e-Babak County. …”
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Use of thermoplastically extruded cereal products in nutrition support of patients with chronic pancreatitis and metabolic disorders by I.M. Fomina, T.V. Gavrish, K.S. Malikov, Yu.V. Ivanova, T.I. Viun, S.V. Viun, K.V. Miasoiedov, S.Yu. Bytiak, Ye.B. Radzishevska

“…It allows creating products with high bioavailability, easy digestibility, and an optimal balance of proteins, fats, and carbohydrates. …”
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Development and validation of a nomogram for differentiating immune checkpoint inhibitor-related pneumonitis from pneumonia in patients undergoing immunochemotherapy: a multicenter... by Linli Duan, Guanglu Liu, Zijie Huang, Rong Chen, Di Mo, Yuxiao Xia, Jiazhu Hu, Mengzhang He

“…Utilizing the random forest machine learning method, optimal development and validation cohort allocation ratios (in a ratio of 8:2) were determined for the predictive model. …”
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Trastuzumab Rechallenge in HER2-Positive Metastatic Breast Cancer: A Promising Strategy for Enhanced Progression-Free Survival Post Ado-Trastuzumab Emtansine Progression by Yunus Emre Altıntaş, Oğuzcan Kınıkoğlu, Anıl Yıldız, Deniz Işık, Uğur Özkerim, Sıla Öksüz, Tuğba Başoğlu Tüylü, Heves Sürmeli, Nedim Turan, Hatice Odabaş

“…Further prospective studies are needed to confirm these findings and optimize treatment sequencing.…”
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ChatGPT-o1 Preview Outperforms ChatGPT-4 as a Diagnostic Support Tool for Ankle Pain Triage in Emergency Settings by Pooya Hosseini-Monfared, Shayan Amiri, Alireza Mirahmadi, Amirhossein Shahbazi, Aliasghar Alamian, Mohammad Azizi, Seyed Morteza Kazemi

“… Introduction: ChatGPT, a general-purpose language model, is not specifically optimized for medical applications. This study aimed to assess the performance of ChatGPT-4 and o1-preview in generating differential diagnoses for common cases of ankle pain in emergency settings. …”
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Deep brain stimulation versus vagus nerve stimulation for the motor function of poststroke hemiplegia: study protocol for a multicentre randomised controlled trial by Bin Liu, Xinguang Yu, Qing Chang, Di Liu, Yanyang Zhang, Junpeng Xu, Haonan Yang, Zhiqi Mao, Guosong Shang, Shuzhen Liu, Zhebin Feng, Chen Yuhan

“…These patients must receive necessary support at home and consent to participate. The aim is to evaluate the effectiveness and safety of DBS and VNS therapies. …”
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Sagittal Plane Kinematic Deviations and Spatio-Temporal Gait Characteristics in Children with Idiopathic Toe Walking: A Comparative Analysis Using Statistical Parametric Mapping by Rocio Pozuelo-Calvo, Almudena Serrano-Garcia, Yolanda Archilla-Bonilla, Angel Ruiz-Zafra, Manuel Noguera-Garcia, Kawtar Benghazi-Akhlaki, Miguel Membrilla-Mesa, Carla DiCaudo, Jose Heredia-Jimenez

“…Future research should explore the long-term musculoskeletal consequences of these deviations and optimize therapeutic strategies, such as physical therapy and orthotic interventions, to improve gait functionality and quality of life.…”
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Adaption of the Memorial Sloan Kettering Cancer Center Nomograms for the Prediction of Prostate Cancer–specific Death in Sweden: A Population-based Cohort Study by Renata Zelic, Marcus Westerberg, Pär Stattin, Hans Garmo, Lorenzo Richiardi, Olof Akre, Andreas Pettersson

“…Both the preoperative and the postoperative model showed high discrimination for prostate cancer–specific death (optimism-corrected C-index: 0.81 and 0.87, respectively), but not for other-cause mortality (0.67, both models). …”
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Impact of Preoperative Biliary Stenting on Intestinal Dysfunction and Perioperative Complications After Pylorus-Preserving Pancreaticoduodenectomy by Gelu Mihai Breaza, Florin Emil Hut, Octavian Cretu, Simona-Alina Abu-Awwad, Ahmed Abu-Awwad, Laurentiu Sima, Radu Gheorghe Dan, Cristina Ana-Maria Dan, Raluca Maria Closca, Flavia Zara

“…Limiting the PBS duration to 2–3 weeks, alongside optimized perioperative management, may help reduce postoperative morbidity and improve surgical outcomes.…”
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Awake versus intubated video-assisted thoracoscopic surgery for pleural disease: a retrospective cohort study from a single tertiary center by Omer Faruk Saglam, Burcu Kilic, Merve Ekinci Fidan, Nevzat Cem Sayilgan, H. Volkan Kara, Akif Turna, Kamil Kaynak, Ezel Ersen

“…Prospective randomized, patient matched larger and multiple study groups are needed and in our future plan to confirm these findings and optimize the perioperative and postoperative protocols for A-VATS.…”
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Clinical outcomes of transcatheter edge-to-edge repair in patients with acute mitral regurgitation complicated by cardiogenic shock: a systematic review and meta-analysis by Ashraf Ahmed, Rafael Contreras, Anoop Gurram, Parsa Saberian, Rasha Kaddoura, Kayla Boyea, Yussif Issaka, Seyyed Mohammad Hashemi, Daniyal Ameen, Sara Nobakht, Ehsan Amini-Salehi, Sandeep Samethadka Nayak

“…However, high heterogeneity and low certainty of evidence highlight the need for further high-quality prospective studies to validate long-term outcomes and optimize patient selection. Clinical trial number Not applicable. …”
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