The effects of anterior spaces on the intrusion of mandibular incisors with clear aligners in extraction cases: a finite-element analysis by Lei Liang, Lu Liu, Yuan Cao, Zhiwei Wang, Ni Li, Yanjiao Li, Fang Jin

“…Notably, moderate spacing optimized the distribution of Von Mises stress from the clear aligner in the anterior region, facilitating a more bodily movement pattern during intrusion rather than excessive tipping. …”
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Assessment of photoreceptor recovery and visual function utilizing adaptive optics and microperimetry in patients with surgically closed macular holes by Yuanyuan Liu, Xueli Yang, Wei Zhou, Jinguo Yu, Song Chen, Tiangeng He, Caiyun You, Xiangda Meng, Mengyu Liao, Yi Lei, Hua Yan

“…Using adaptive optics scanning laser ophthalmoscopy (AOSLO) and microperimetry, we aimed to provide a more detailed understanding of photoreceptor recovery and visual improvement in closed MHs. …”
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Increased autophagy activity regulated by LC3B gene promoter DNA methylation is associated with progression to active pulmonary tuberculosis disease by Yung-Che Chen, Ying-Tang Fang, Chao-Chien Wu, Tung-Ying Chao, Yi-Hsi Wang, Chia-Cheng Tseng, Sum-Yee Leung, Chiu-Ping Lee, Ting-Ya Wang, Po-Yuan Hsu, Jen-Chieh Chang, Meng-Chih Lin, Chang-Chun Hsiao

“…Abstract Background This study aims to explore the role of autophagy-associated genes (ATG) and their epigenetic markers in the progression of mycobacterium tuberculosis (M. tb) infection, and to test the effects of de-methylation agents on macrophage functions against TB. …”
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Biochemical recurrence prediction after robot-assited radical prostatectomy (BCR-PRARP) by Tanan Bejrananda, Kiyoshi Takahara, Dutsadee Sowanthip, Tomonari Motonaga, Kota Yagi, Wataru Nakamura, Masanobu Saruta, Takuhisa Nukaya, Masashi Takenaka, Kenji Zennami, Manabu Ichino, Hitomi Sasaki, Makoto Sumitomo, Ryoichi Shiroki

“…Objective: This study aimed to establish a robust predictive model for biochemical recurrence (BCR) in patients with prostate cancer who underwent robot-Assisted Radical Prostatectomy. …”
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Feasible and Rapid Screening of <i>IDH1/2</i> and <i>FLT3-TKD2</i> Mutations by High-Resolution Melting for Patients with Acute Myeloid Leukemia by José Vicente Gil, Sandra de las Heras, Alberto Miralles, Claudia Sargas, Marta Llop, Rebeca Rodríguez-Veiga, Laura Torres-Miñana, Blanca Boluda, Isabel Cano-Ferri, Evelyn Acuña-Cruz, Irene Navarro, Pilar Lloret-Madrid, Pau Montesinos, Eva Barragán

“…Rapid mutational analysis is crucial for timely and optimal therapy selection. This study aims to develop and validate a rapid, cost-effective, and sensitive screening method for detecting <i>IDH1</i>, <i>IDH2</i>, and <i>FLT3</i>-TKD2 mutations using polymerase chain reaction (PCR) and high-resolution melting curve analysis (HRM). …”
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Predicting the risk of postoperative avascular necrosis in patients with talar fractures based on an interpretable machine learning model by Jian Zhang, Jian Zhang, Jian Zhang, Jihai Xu, Jihai Xu, Jiapei Yu, Jiapei Yu, Jiapei Yu, Hong Chen, Hong Chen, Xin Hong, Songou Zhang, Xin Wang, Xin Wang, Chengchun Shen, Chengchun Shen, Chengchun Shen

“…The SHapley Additive exPlanations (SHAP) provided global and local explanations for the optimal model.ResultsA total of 207 patients with talar fractures were enrolled in our study, with 45 (21.74%) developed AVN, and 162 (78.26%) did not. …”
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A national survey of suicidality and non-suicidal self-injury in bipolar disorder: insights from network analysis by Lvchun Cui, Yuncheng Zhu, Yang Li, Jia Zhou, Guiyun Xu, Miao Pan, Zhiyu Chen, Wenfei Li, Zhian Jiao, Mingli Li, Yong Zhang, Jingxu Chen, Xiuzhe Chen, Na Li, Jing Sun, Jian Zhang, Shaohua Hu, Haishan Wu, Zhaoyu Gan, Yan Qin, Yumei Wang, Yantao Ma, Xiaoping Wang, Xiaohong Li, Chuangxin Wu, Yiyun Cai, Jiaye Chen, Baichuan Wu, Zuowei Wang, Daihui Peng, Yiru Fang

“…Understanding the nature of suicidality and NSSI in BD is an important way to inform optimal intervention for reducing suicide risk. We aimed to investigate the prevalence and correlates of SI, SA, and NSSI in patients with BD using data from a national survey. …”
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The efficacy and safety of first-line monotherapies in primary therapy of invasive aspergillosis: a systematic review by Yan Chen, Yan Chen, Jiaojiao Zhao, Jiaojiao Zhao, Yifei Wang, Yifei Wang, Long Ge, Long Ge, Joey Sum-wing Kwong, Junjie Lan, Rui Zhang, Huaye Zhao, Linfang Hu, Jiaxue Wang, Shuimei Sun, Songsong Tan, Xiaoqing Lin, Rui He, Wenyi Zheng, Xiaosi Li, Jiaxing Zhang

“…Furthermore, the risk of AEs and SAEs was comparable for the three triazoles, but the risk of SAEs was significantly higher for D-AmB than others.ConclusionThe efficacy and safety of triazoles are more favorable than D-AmB in the primary therapy of IA, with ISA being the optimal choice.Systematic Review RegistrationPROSPERO CRD42023407632.…”
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Atrial Fibrillation Termination Success During Ablation: Insights From Pooled Clinical Studies by Changjian He, Wenchang Zhang, Feng Li, Huaiqiang Wang, Xiongyi Han, Zihan Zhao, Guojie Ye, Tengfei Liu, Da Zhang, Haiyan Liu, Jie Liu, Jingning Zhao, Chunhua Ding

“…Background: The optimal endpoint for ablation in persistent atrial fibrillation (pers-AF) remains unclear. …”
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Dietary taurine supplementation can improve the growth, protein metabolism, immunity and muscle development of larval largemouth bass (Micropterus salmoides) by Qing Zhou, Siying Hu, Jiacheng Yu, Can Li, Xi Liu, Chen Zhou, Chengmin Zhao, Kai Luo, Weihua Gao, Chenglong Wu

“…This study aimed to explore the impact of dietary taurine supplementation on the growth, amino acid transport, protein metabolism, immunity, and muscle and skeletal development of larval largemouth bass (Micropterus salmoides). …”
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STOP-Colitis pilot trial protocol: a prospective, open-label, randomised pilot study to assess two possible routes of faecal microbiota transplant delivery in patients with ulcerat... by Ailsa L Hart, Christel McMullan, Jonathan Mathers, Laura Magill, Natalie J Ives, Tariq Iqbal, Mohammed Nabil Quraishi, Naveen Sharma, Jonathan Segal, Richard Hansen, Mehmet Yalchin, Clare Blackwell, Peter Hawkey, Victoria McCune, Daniel Gaya, Shrushma Loi, Konstantinos Gerasimidis, Nicholas James Loman, Christopher Quince, Nicola Crees

“…Patients will be followed up weekly for 8 weeks, and then at 12 weeks. The aims of this pilot study are (1) to determine which FMT administration route (NG or COLON) should be investigated in a randomised double-blind, placebo-controlled trial and (2) to determine if a full randomised controlled trial is feasible. …”
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Prophylactic VA-ECMO During Complex High-Risk PCI by Chenliang Pan, MD, Youqi Zhu, MD, Jing Zhao, MD, Bo Zhang, MD, Sixiong Hu, MD, Cunrui Zhao, MD, Xiaoxue Meng, MD, Xinghu Zhou, MD, Yurun Su, MD, Erkun Xing, MM, Peng Lei, MD, Nan Bai, MD, Juan Ma, MD, Xiaojuan Wang, MD, Andong Lu, MD, Ming Bai, MD

“…Objectives: The authors aimed to assess the safety and effectiveness of prophylactic VA-ECMO during PCI. …”
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Contribution of Human Resources for Health competence and skill mix on compliance with healthcare quality standards among Primary Healthcare Facilities in Tanzania: evidence from d... by Syabo M. Mwaisengela, Patricia A. Materu, Chrisogone J. German, Issa I. Mmbaga, Danny J. Temba, Raymond R. Kiwesa, Martin S. Mapunda, Erick S. Kinyenje, Nathanael Sirili, Pankras W. Luoga, Simon P. Ernest, Joseph M. Burra, Joseph C. Hokororo, Godfrey Kacholi, Ntuli A. Kapologwe, Mackfallen G. Anasel, Claud J. Kumalija, Michael Habtu, Grace E. Saguti, Janeth S. Masuma, Talhiya A. Yahya, Eliudi S. Eliakimu

“…Inadequate numbers with poor skill mix compromise health system functioning that negatively affect delivery of quality healthcare services. Objective This study aims to study the effect of HRH skills and competence mix on the compliance with healthcare quality standards (HCQS) among dispensaries in Tanzania. …”
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The Choice of Tactics for Surgical Treatment of Acute De Bakey Type I Aortic Dissection in a Multidisciplinary Surgical Hospital by A. V. Redkoborody, V. S. Selyaev, N. V. Rubtsov, L. S. Kokov, R. Sh. Muslimov, I. E. Popova, K. M. Torshkhoyev, L. G. Khutsishvili

“…Despite the improvement of surgical technologies, hospital mortality after emergency surgical interventions is 17–25%, in complicated cases it can reach 80–90%.AIM OF STUDY Description of the perioperative treatment tactics adopted at the N.V. …”
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Serum KL-6 levels predict clinical outcomes and are associated with MUC1 polymorphism in Japanese patients with COVID-19 by Takanori Kanai, Yukinori Okada, Yasunori Sato, Katsunori Masaki, Takanori Asakura, Kaori Sakurai, Yuko Kitagawa, Koichi Fukunaga, Hirofumi Kamata, Makoto Ishii, Naoki Hasegawa, Ryuji Koike, Ho Lee, Ryuya Edahiro, Shotaro Chubachi, Kensuke Nakagawara, Ho Namkoong, Hiromu Tanaka, Seiya Imoto, Shuhei Azekawa, Shiro Otake, Takahiro Fukushima, Mayuko Watase, Tatsuya Kusumoto, Akinori Kimura, Satoru Miyano, Seishi Ogawa

“…An optimal serum KL-6 level cut-off to predict critical outcomes was determined and used for multivariable logistic regression analysis. …”
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An urgent call for more ambitious ocean literacy strategies in marine protected areas: a collaboration project with small-scale fishers as a case study by Janire Salazar, Janire Salazar, Sílvia Gómez, Begoña Vendrell-Simón, Begoña Vendrell-Simón, Begoña Vendrell-Simón, Miroslav Pulgar, Núria Viladrich, Núria Viladrich, Núria Viladrich, Stefano Ambroso, Stefano Ambroso, Stefano Ambroso, Patricia Baena, Andreu Santín, Andreu Santín, Maria Montseny, Maria Montseny, Marina Biel-Cabanelas, Josep-Maria Gili

“…Furthermore, a list of recommendations is provided to optimize the multisector opportunities emerging from collaborative projects with marine scientists and fishers in MPAs.…”
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Limitations of human t-lymphotropic virus type 1 antibody testing in hospitals of endemic regions in China by Yi Chen, Yanxin Chen, Jing Zheng, Jiajie Yang, Jiajie Yang, Jiajie Yang, Yong Wu, Jianda Hu, Jianda Hu, Jianda Hu, Zhengjun Wu

“…A receiver operating characteristic (ROC) curve analysis determined that a threshold of 0.335 signal-to-cutoff (S/CO) was optimal for classifying positive antibody test results, yielding a sensitivity of 86.3% and a specificity of 94.4%.ConclusionThe Wantai HTLV-1 antibody test kit, when utilized in hospitals within endemic regions, exhibits a high level of specificity. …”
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Bio-Prospecting Xylose-Utilizing, Exopolysaccharide (EPS)-Producing Bacteria and EPS Quantification through Submerged Fermentation using Xylose as the Major Carbon Source by Antia, U., Stephen, N., Umoh, V., Bassey, M., Udo, I., Adeleke, A. J.

“…Bacterial isolates capable of utilizing xylose for EPS production were obtained from various sources, showing potential for further optimization…”
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Modeling human capital strategies with an emphasis on organizational structure change by Shahriyar Emamdoust Haredasht, Musa Rezvani Chaman Zamin, Morteza Hazrati

“…Therefore, a deep understanding of organizational theory and strategy is needed so that the organization can develop more optimally, and strategy design is a process of a set of activities aimed at creating the vision and mission of the organization (2021, Munawar). …”
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Designing a Smart Leadership Model for Education Managers by mehdi oliyaee, aliakbar ajam, Ahmad Akbari, turaj falah mehne

“…Abstract The aim of the present study is to design a smart leadership model for education managers. …”
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