Predictive Potential of Contrast-Enhanced MRI-Based Delta-Radiomics for Chemoradiation Responsiveness in Muscle-Invasive Bladder Cancer by Kohei Isemoto, Yuma Waseda, Motohiro Fujiwara, Koichiro Kimura, Daisuke Hirahara, Tatsunori Saho, Eichi Takaya, Yuki Arita, Thomas C. Kwee, Shohei Fukuda, Hajime Tanaka, Soichiro Yoshida, Yasuhisa Fujii

“…The subtraction of radiological features between CE- and NE-T1WI yielded 112 delta-radiomics features, which were utilized in multiple machine-learning algorithms to construct optimal predictive models for CRT responsiveness. …”
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Self-DSNet: A Novel Self-ONNs Based Deep Learning Framework for Multimodal Driving Distraction Detection by Mamun Or Rashid, Md. Mosarrof Hossen, Mohammad Nashbat, Mazhar Hasan-Zia, Ali K. Ansaruddin Kunju, Amith Khandakar, Azad Ashraf, Molla Ehsanul Majid, Saad Bin Abul Kashem, Muhammad E. H. Chowdhury

“…We employed a publicly available multimodal dataset encompassing three data categories: physiological, vehicle dynamics, and vision-based data. Our approach aims to identify the normal state and three types of distractions: cognitive, emotional, and sensorimotor. …”
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Benefit of implantable cardioverter defibrillator use in Japanese patients based on modified MADIT‐ICD benefit score by Toshinori Chiba, Yusuke Kondo, Yuki Shiko, Masahiro Nakano, Kajiyama Takatsugu, Miyo Nakano, Ryo Ito, Masafumi Sugawara, Yutaka Yoshino, Satoko Ryuzaki, Yukiko Takanashi, Yuya Komai, Yoshio Kobayashi

“…Abstract Aims The MADIT‐ICD benefit score is used to stratify the risk of life‐threatening arrhythmia and non‐arrhythmic mortality. …”
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Seed Germination Responses to Temperature and Osmotic Stress Conditions in <i>Brachiaria</i> Forage Grasses by Francuois L. Müller, Jabulile E. Leroko, Clement F. Cupido, Igshaan Samuels, Nothando Ngcobo, Elizabeth L. Masemola, Fortune Manganyi-Valoyi, Tlou Julius Tjelele

“…<i>Brachiaria</i> forages are known to be drought-tolerant as mature plants, but no information about drought tolerance at the seed germination stage is currently available. This study aimed to determine the impacts of different temperature and moisture conditions on the seed germination characteristics of five <i>Brachiaria</i> genotypes. …”
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Impact of different soils and temperature in adsorption-desorption of herbicide butachlor by Deepika Bamal, Anil Duhan, Ravi Kumar Beniwal, Jayant Sindhu, Rahul Kumar Dhaka, Vidhi Dhanda, Ajay Pal, Sachin Dhanda, Virender Singh Hooda, Pankaj Kumar, Rajpaul Yadav

“…Both adsorption and desorption isotherm are well described by the Freundlich equation. Adsorption was optimal at 25 °C, followed by a sharp decline at higher temperatures. …”
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Unsupervised machine learning clustering approach for hospitalized COVID-19 pneumonia patients by Nuttinan Nalinthasnai, Ratchainant Thammasudjarit, Tanapat Tassaneyasin, Dararat Eksombatchai, Somnuek Sungkanuparph, Viboon Boonsarngsuk, Yuda Sutherasan, Detajin Junhasavasdikul, Pongdhep Theerawit, Tananchai Petnak

“…Abstract Background Identification of distinct clinical phenotypes of diseases can guide personalized treatment. This study aimed to classify hospitalized COVID-19 pneumonia subgroups using an unsupervised machine learning approach. …”
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Formulation and In Vitro Evaluation of Matrix Tablets Containing Ketoprofen–Beta Cyclodextrin Complex for Enhanced Rheumatoid Arthritis Therapy: Experimental and Computational Insi... by Monica Stamate Cretan, Lacramioara Ochiuz, Vlad Ghizdovat, Monica Molcalut, Maricel Agop, Carmen Anatolia Gafițanu, Alexandra Barsan (Bujor), Mousa Sha’at, Ciprian Stamate

“…<b>Background:</b> Rheumatoid arthritis is a chronic autoimmune disease that leads to severe disability and requires improved therapeutic strategies to optimize anti-inflammatory treatment. This study aimed to address this challenge by developing and characterizing an extended-release polymer matrix tablet containing ketoprofen and a ketoprofen–β-cyclodextrin complex with enhanced therapeutic properties. …”
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The blood lactate/serum albumin ratio might represent a good prognostic indicator of 28-day mortality in patients with acute respiratory distress syndrome: a retrospective observat... by Jiahao Chen, Chang Gao, Ling Yang, Lijuan Yang, Ying He, Shiqi Guo, Yuanxiao Sun, Siyu He, Qiang Guo

“…After grouping according to an LAR optimal cutoff value of 0.07, 28-day mortality was significantly higher in the high-LAR group than in the low-LAR group (47.18 vs. 12.69, P < 0.001). …”
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Bridging the gap: clinical translation of adipose-derived stem cells - a scoping review of clinical trials by Hankun Su, Hoksan Chau, Qilin Li, Fen Xiao, Yuanyuan Sun, Jingjing Chen, Yayi He, Jinyao Ning, Qin Hu, Yujie Xiao, Caiwen Li, Bixia Huang, Jing Zhao, Yanping Li, Hui Li

“…Objective This scoping review, complemented by bibliometric analysis, aims to map the landscape of randomized controlled trials (RCTs) evaluating ADSC therapies, identify gaps between basic research and clinical translation, and highlight emerging trends in the field. …”
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Comparison of admitting neutrophil/lymphocyte ratio with baseline NIH stroke scale score in discriminating poor 30-day stroke outcome among Nigerian Africans by Oladotun V. Olalusi, Oladotun V. Olalusi, Joseph Yaria, Akintomiwa Makanjuola, Rufus Akinyemi, Rufus Akinyemi, Rufus Akinyemi, Mayowa Owolabi, Mayowa Owolabi, Mayowa Owolabi, Mayowa Owolabi, Mayowa Owolabi, Adesola Ogunniyi, Adesola Ogunniyi

“…AimThe National Institutes of Health Stroke Scale (NIHSS) score is an established marker of stroke severity. …”
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Role of renin-angiotensin-aldosterone system gene polymorphisms in the development of diastolic dysfunction in female patients with hypertension by Mariya A. Grenaderova, Nadezhda V. Izmozherova, Elena V. Kudryavtseva, Muraz A. Shambatov, Danila L. Zornikov, Artem A. Popov, Anna A Vikhareva, Daniil O. Kornilov, Mikhail A. Tryapitsyn, Veronika M. Simarzina, Aleksey A. Bekhter

“…AIM: To assess the frequency of single-nucleotide polymorphisms in renin-angiotensin-aldosterone system genes and their contribution to the development of diastolic dysfunction. …”
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Comparative methodological studies of L-asparaginase encapsulation into erythrocytes by D. V. Borsakova, M. E. Plakhotnik, L. D. Koleva, E. A. Bovt, Yu. G. Alexandrovich, F. I. Ataullakhanov, E. I. Sinauridze

“…Activity of L-asparaginase, volume, hematocrit, hematological indices and osmotic cell fragility of erythrocytes were measured in the suspensions of erythrocytes before and after the enzyme encapsulation procedure.Results. An optimal osmolality of the hypotonic buffer for each method was selected and was equal to 90–110 mOsm/kg. …”
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Predictors of successful recanalization following endovascular intervention in non-acute basilar artery occlusion by Ying Liu, Zuoli Wu, Zuoli Wu, Shengwei Wei, Wenbo He, Weihao Ye, Shang Xu, Baozi Huang, Chao Qin, Wen Gao, Ziming Ye

“…The proposed scoring system can help screen patients suitable for treatment and optimize treatment strategies, but further validation in prospective cohorts is needed.…”
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Game on or game over? Gamification from 360-degree perspective, perception, confidence, and challenges in simulation based nursing education: mixed-method study by Mohamed Hashem Kotp, Hasan Ahmed Awad Bassyouny, Mohamed Ahmed Aly, Rasha Kadri Ibrahim, Abdelaziz Hendy, Ahmed Shaaban Attia, Ahmed Khalaf Mekdad, Ahmed Ali Hafez, Sally Mohammed Farghaly Abdelaliem, Nadiah A. Baghdadi, Ahmed Hendy, Hossam Ali Ismail

“…However, successful implementation requires institutional support, faculty training, and standardized evaluation tools to overcome existing challenges and optimize educational outcomes. The study provides validated tools and empirical insights into gamification in nursing education. …”
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Quantitative Measures of Pure Ground-Glass Nodules from an Artificial Intelligence Software for Predicting Invasiveness of Pulmonary Adenocarcinoma on Low-Dose CT: A Multicenter St... by Yu Long, Yong Li, Yongji Zheng, Wei Lin, Haomiao Qing, Peng Zhou, Jieke Liu

“…Among the quantitative measures of diameter, volume, attenuation, and mass, mass was the most optimal predictor of invasiveness in pulmonary adenocarcinomas on LDCT, which might be used to assist clinical decision of pGGNs during lung cancer screening.…”
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The Prognostic Value of Nutritional and Immune Indices for Stage IB Non‐Small Cell Lung Cancer Patients: Insights From a Retrospective Cohort Study by Jianqi Hao, Song He, Cong Chen, Wenying Xu, Xiaohu Hao, Nanzhi Luo, Chenglin Guo, Qiang Pu, Lunxu Liu

“…The nomogram model indicated that preoperative PNI was the optimal predictor for postoperative recurrence, achieving the highest C‐index (0.658). …”
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Research on the directional fracturing mechanism of multiborehole rock mass plasma blasting by Xue LI, Chuanbing WANG, Yanbing WANG, Hongjia MEI, Yanqing LI, Zhaoyang WANG, Diancai XIAO

“…At a 40-mm slot spacing, the precut groove rock specimens exhibited optimal energy convergence from plasma electric pulses, forming a coupling surface along the precut groove line. …”
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Clinical potential and experimental validation of prognostic genes in hepatocellular carcinoma revealed by risk modeling utilizing single cell and transcriptome constructs by Hang Deng, Xu Wang, Zi-Ang Jiang, Jian Xu, Yu Zhang, Yao Zhou, Jun Gong, Xiang-Yu Lu, Yi-Fu Hou, Hao Zhang

“…Subsequently, univariate Cox regression analysis and PH assumption test were performed, and a risk model was developed using an optimal algorithm from 101 combinations on the TCGA-LIHC dataset to pinpoint prognostic genes. …”
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Machine learning-based predictive model for acute pancreatitis-associated lung injury: a retrospective analysis by Zhaohui Du, Qiaoling Ying, Yisen Yang, Huicong Ma, Hongchang Zhao, Jie Yang, Zhenjie Wang, Chuanming Zheng, Shurui Wang, Qiang Tang

“…These two models were selected as the optimal models for the development of an online calculator for clinical applications and risk stratification.ConclusionWe developed and internally validated a machine learning model to predict APALI, showing strong performance in our study population. …”
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Evidence of high carbon biodegradability in the subsoil of Mediterranean croplands by W. Khairallah, D. Raclot, M. Annabi, G. Coulouma, B. Guenet, C. Rumpel, H. Bahri

“…Deep soil horizons are thought to contain mostly organic carbon stabilised at centennial or even millennia time scales. The present study aimed to investigate the common paradigm of high stability of soil carbon in deep soil horizons in semiarid Mediterranean cultivated environments. …”
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