Formulation and Optimization of Monolithic Fixed-Dose Combination of Metformin HCl and Glibenclamide Orodispersible Tablets by Anteneh Belayneh, Fantahun Molla, Getu Kahsay

“…However, the pill burden of this combination therapy combined with swallowing difficulties, occurring at a later stage of DM, has been the major challenge for successful treatment outcomes. This study was aimed at formulating and optimizing a monolithic fixed-dose combination (FDC) of metformin (MET) and glibenclamide (GLB) orodispersible tablets (ODTs) to overcome both the pill burden and swallowing problems. …”
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Unified Dynamic Dictionary and Projection Optimization With Full-Rank Representation for Hyperspectral Anomaly Detection by Hongran Li, Chao Wei, Yizhou Yang, Zhaoman Zhong, Ming Xu, Dongqing Yuan

“…Hyperspectral anomaly detection (HAD) aims to classify each pixel in a hyperspectral image as either background or anomaly without requiring labeled data. …”
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Accuracy Optimization of Robotic Machining Using Grey-Box Modeling and Simulation Planning Assistance by Minh Trinh, Michael Königs, Lukas Gründel, Marcel Beier, Oliver Petrovic, Christian Brecher

“…The aim of this paper is to develop an approach to increase the accuracy of industrial robots for machining processes. …”
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Land carrying capacity status and land utilization optimization strategy in South Sorong, Indonesia by Hendrik Kondong, Andri Kurniawan, Langgeng Wahyu Santosa

“…At its core, the issue is whether the available land can be used most effectively since lousy management can lead to land degradation. This study aimed to identify the status of land carrying capacity and various strategies that can be carried out to optimize land in South Sorong, Indonesia. …”
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Reducing drilling cost of geothermal wells by optimizing drilling operations: Cost effective study by M.Y. Amer, S.K. Salem, M.S. Farahat, A.M. Salem

“…Therefore, it is highly important to analyze the drilling operations in terms of costs and optimization. This study aims to investigate the drilling operations of one deepest oil well (well AG-119x) in the Abu Al-Gharadig Area, western desert of Egypt. …”
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G-OPTIMAL DESIGN OF NON-LINEAR MODEL TO INCREASE PURITY LEVELS OF SILICON DIOXIDE by Nindya Wulandari, Erfiani Erfiani, Irzaman Irzaman, Utami Dyah Syafitri

“…A purity procedure can raise the purity of low-quality silica by altering the temperature and rate of temperature rise. This study aims to obtain the best design for increasing SiO2 levels—the G-optimal design on a non-linear model using the Variable Neighborhood Search (VNS) algorithm. …”
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Optimizing the feeding frequency to maximize the production of sterile males in tsetse mass-rearing colonies. by Soumaïla Pagabeleguem, Ange Irénée Toé, Sié Hermann Pooda, Kiswendsida Mikhailou Dera, Abdou Salam Belem, Adrien Marie Gaston Belem, Gisèle Marie Sophie Ouedraogo/Sanou, Mamadou Ira, Bénéwendé Aristide Kaboré, Lassané Percoma, Issa Sidibé

“…The Insectarium de Bobo-Dioulasso (IBD) was created and equipped in the frame of Pan African Tsetse and Trypanosomosis Eradication Campaign (PATTEC) with the main goal to provide sterile males for the different eradication programs in West Africa which is already the case with the ongoing eradication program in Senegal. The aim of this study was to identify the best feeding regime in mass-rearing colonies of Glossina palpalis gambiensis to optimize the yield of sterile males. …”
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Extraction of Bioactive Compounds from Yellow Onion Peels: Taguchi-SAW Hybrid Optimization by Mehmet Güldane, Ali Cingöz

“…The aim of this study was to obtain an extract rich in bioactive components from yellow onion peels, which are generally considered waste material. …”
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Topology Optimization of Automotive Vibration Test Jig: Natural Frequency Maximization and Weight Reduction by Jun Won Choi, Min Gyu Kim, Jung Jin Kim, Jisun Kim

“…Vibration test jigs are essential components for evaluating the dynamic performance and durability of automotive parts, such as lamps. This study aimed to derive optimal jig configurations that simultaneously maximize natural frequency and minimize structural weight through topology optimization. …”
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Optimization of psychosocial rehabilitation of patients with schizoaffective disorder according to a typology of pathopersonological transformations by M. Ye. Khomitskyi

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Optimizing Farmers’ and Intermediaries’ Practices as Determinants of Food Waste Reduction Across the Supply Chain by Abdelrahman Ali, Yanwen Tan, Shilong Yang, Chunping Xia, Wenjun Long

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Review of Thermal Calculation Methods for Boilers—Perspectives on Thermal Optimization for Improving Ecological Parameters by Bartosz Ciupek, Andrzej Frąckowiak

“…Therefore, it should be recognized that activities aimed at improving the thermal parameters of boilers should directly improve the thermal efficiency of the device, and this will translate into fuel savings and reduce their negative impact on the environment.…”
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Optimizing land use for carbon neutrality: A scenario analysis in the Jakarta metropolitan area by Runsen Zhang, Chui Ying Lee, Marissa Malahayati, Yan Xu, Shin-ichi Onodera, Mitsuyo Saito, Iwan Ridwansyah, Ruci Wang

“…The model incorporated carbon dioxide (CO2) emission constraints to direct the structural optimization and spatial distribution of land use, with the aim of minimizing overall CO2 emissions. …”
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Strategy Design and Parameter Optimization of High-Frequency Resonance Suppression for Modular Multilevel Converter by Xiao ZHOU, Yuexi YANG, Longze KOU, Yunfeng LI, Xuewei QIAN, Jie HAO, Weizhe JING

“…This scheme aims to alter the impedance characteristics of the converter station from a passive perspective, thereby achieving reliable suppression of high-frequency oscillations. …”
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Optimizing Ordering Policies for Imperfect Inventory Systems Integrating Trade Credit and Carbon Emission by Sahil Bhardwaj, Sudhir Kumar Chauhan, Mandeep Mittal, Leopoldo Eduardo Cárdenas-Barrón, Riju Chaudhary

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Optimizing electrical output performance of triboelectric nanogenerators by micro-/nano-morphology design and fabrication by Jiaxin Han, Xingyi Dai, Long-Biao Huang, Jianhua Hao

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Evaluation of commuter perception and optimization of public transit routes in Hyderabad using TOD applications by Sania Rehman, Mir Aftab Hussain Talpur, Ali Raza Khoso, Imtiaz Ahmed Chandio, Furqan Javed Arain

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The Development of an Optimized Impact Pad for a Six-Strand Tundish Using CFD Simulations by Peter Demeter, Branislav Buľko, Róbert Dzurňák, Ivan Priesol, Slavomír Hubatka, Lukáš Fogaraš, Martina Hrubovčáková, Jaroslav Demeter

“…This paper presents a detailed numerical analysis aimed at designing an optimally shaped impact pad. …”
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Optimizing Patient Access to Orphan Medicinal Products: Lessons from Central and Eastern Europe by Tomasz Kluszczynski, Bertalan Nemeth, Magdalena Władysiuk, Marcin Czech, Maria Kamusheva, Nicolae Fotin, Sandra Rose, Tomáš Doležal, Rok Hren

“…While these jurisdictions have undergone rapid healthcare transformations, significant disparities in OMP access persist compared to Western Europe. This study aimed to address this gap by identifying barriers and enablers to optimize patient access to OMPs in a sustainable and equitable manner. …”
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Evaluation and Optimization Strategies for Forest Landscape Stability in Different Landform Types of the Loess Plateau by Mei Zhang, Peng Liu, Zhong Zhao

“…This study aims to develop a forest landscape stability assessment framework that integrates structure, function, and resilience to assess forest landscape stability under different landform types on the Loess Plateau, and to propose differentiated optimization strategies. …”
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