Associations of accelerated biological ageing with incident dementia, cognitive functions and brain structure: a prospective cohort study based on UK Biobank by Xiao Ren, Xiaowei Zheng, Yonghong Zhang, Zhengbao Zhu, Mengyao Shi, Pinni Yang, Lulu Sun, Ruirui Wang, Yiqun Li, Wenyang Han, Minglan Jiang, Yiming Jia

“…Background Several small-sample studies have suggested that biological processes of ageing are implicated with dementia and cognitive function. We aimed to prospectively investigate the associations of biological age with incident dementia, cognitive functions and brain structure based on the UK Biobank.Methods A total of 287 846 participants without dementia at baseline (followed until November 2022) were analysed. …”
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Dietary functional palatability enhancer improved growth and appetite in largemouth bass (Micropterus salmoides) fed a reduced fish meal diet by Xinyan Zhi, Yixin Gu, Wenli Zhao, Shichao Xie, Yangguang Bao, Sofia Morais, Dong Li, Maolong He, Min Jin, Qicun Zhou

“…This study aimed to investigate the feasibility of using a functional palatability enhancer (PE) to promote healthy growth of largemouth bass (Micropterus salmoides). …”
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Preliminary results of the EPIDIA4Kids study on brain function in children: multidimensional ADHD-related symptomatology screening using multimodality biometry by Yanice Guigou, Alexandre Hennequin, Théo Marchand, Théo Marchand, Mouna Chebli, Lucie Isoline Pisella, Pascal Staccini, Pascal Staccini, Vanessa Douet Vannucci, Vanessa Douet Vannucci

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CORRELATIONS OF DIFFERENT STRUCTURAL AND FUNCTIONAL CHARACTERISTICS OF ARTERIAL WALL WITH TRADITIONAL CARDIOVASCULAR RISK FACTORS IN HEALTHY PEOPLE OF DIFFERENT AGE. PART 2 by I. D. Strazhesko, O. N. Tkacheva, D. U. Akasheva, E. V. Dudinskaya, M. V. Agaltsov, A. S. Kruglikova, N. V. Brailova, V. S. Pykhtina, E. V. Plokhova, N. V. Sharashkina, O. Yu. Isaykina, V. A. Vygodin, S. A. Boytsov

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Spatiotemporal dynamic changes of meningeal microenvironment influence meningeal lymphatic function following subarachnoid hemorrhage: from inflammatory response to tissue remodeli... by Bingrui Zhu, Changming Liu, Ming Luo, Jiarui Chen, Sixuan Tian, Tiantong Zhan, Yibo Liu, Haocheng Zhang, Zhen Wang, Jianmin Zhang, Yuanjian Fang, Sheng Chen, Xiaoyu Wang

“…We aimed to investigate the meningeal transcriptional response post-SAH and elucidate the dynamic influence of meningeal microenvironment on meningeal lymphatic function. …”
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CORRELATIONS OF DIFFERENT STRUCTURAL AND FUNCTIONAL CHARACTERISTICS OF ARTERIAL WALL WITH TRADITIONAL CARDIOVASCULAR RISK FACTORS IN HEALTHY PEOPLE OF DIFFERENT AGE. PART 1 by I. D. Strazhesko, O. N. Tkacheva, D. U. Akasheva, E. V. Dudinskaya, M. V. Agaltsov, A. S. Kruglikova, N. V. Brailova, V. S. Pykhtina, E. V. Plokhova, N. V. Sharashkina, O. Yu. Isaykina, V. A. Vygodin, S. A. Boytsov

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MT1G promotes iron autophagy and inhibits the function of gastric cancer cell lines by intervening in GPX4/SQSTM1 by Kaiqiang Meng, Jian Song, Fan Qi, Jiamin Li, Zhichao Fang, Liang Song

“…However, the role and potential mechanisms of MT1G in GC have not been fully elucidated. This study aims to explore the biological functions and regulatory mechanisms of MT1G in GC. …”
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Changes in brain functional connectivity and clinical correlations in neuromyelitis optica spectrum disorder: a longitudinal resting-state fMRI study by Jiyuan Wang, Jing Huang, Xiong Kang, Huiqing Dong, Jie Lu

“…Abstract Objectives Neuromyelitis Optica Spectrum Disorder (NMOSD) affects the optic nerves and spinal cord, but its longitudinal effects on brain function remain unclear. This study aims to examine changes in brain functional connectivity over time in NMOSD patients and assess their correlation with clinical outcomes, and explore whether shifts in connectivity, especially within the default-mode hub Brodmann area 23 (BA23), are indicative of changes in clinical status. …”
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A Prospective Interventional Study to Assess Functional Outcomes of Suprapatellar vs Infrapatellar Approaches for Intramedullary Interlocking Nailing in Tibial Shaft Fractures by Santhosh Kumar Kesavan, Dilip Kumar Naidu, Sabari Vaasan L, Rajavel Kalirajan, Gowthaman Nambiraj, Kevin J Dhas

“…Even though infrapatellar nailing (IPN) is commonly done, suprapatellar nailing (SPN) has gained popularity in recent times, with conflicting evidence on their comparative efficacy. Aims and objectives: This prospective interventional study compared the functional outcomes of tibial fractures treated with suprapatellar (SP) vs infrapatellar (IP) intramedullary interlocking nailing (IMIL). …”
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A dynamic knee function scoring system for anterior cruciate ligament injuries based on normative six-degree-of-freedom gait pattern by Junqiao Li, Yunhe Mao, Tian Lan, Liang Huangfu, Yan Xiong, Jian Li

“…Hence, a dynamic scoring system for knee function is needed in clinical settings. This study aimed to propose a dynamic scoring system based on a large sample of normative six-degree-of-freedom (6-DOF) knee kinematics during gait, and validate its correlation with conventional outcome measurements in assessing ACL-injured knees. …”
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Exploring the interplay between pain processing mechanisms, psychosocial factors, and functional outcomes in patients with chronic low back pain: an exploratory study by Jaime Jordán-López, María D. Arguisuelas, Julio Doménech, M. Lourdes Peñalver-Barrios, Marta Miragall, Rocío Herrero, Rosa M. Baños, Juan J. Amer-Cuenca, Juan F. Lisón

“…This present study aimed to explore correlations between pain intensity and pain processing mechanisms (quantitative sensory testing [QST]), psychological factors (kinesiophobia, catastrophising, and anxiety), and functional outcomes (lumbar flexion-evoked pain thresholds and functional capacity) in individuals with CLBP.Methods In this exploratory study we recruited 50 patients with CLBP from a tertiary hospital in Valencia, Spain. …”
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Development and external validation of a dynamic nomogram for predicting the risk of functional outcome after 90 days in patients with acute intracerebral hemorrhage by Shaojie Li, Hongjian Li, Jiani Chen, Baofang Wu, Jiayin Wang, Chaocan Hong, Changhu Yan, Weizhi Qiu, Yasong Li, Hongzhi Gao

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A deep machine learning model development for the biomarkers of the anatomical and functional anti-VEGF therapy outcome detection on retinal OCT images by B.E. Malyugin, S.N. Sakhnov, L.E. Axenova, K.D. Axenov, E.V. Kozina, V.V. Vronskaya, V.V. Myasnikova

“…Predictors of this anatomical outcome, as well as predictors of functional outcome or final visual acuity, can be assessed using optical coherence tomography (OCT). …”
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The effect of the universal test and treat strategy on the kidney function in adults living with HIV in Zambia: A six-month multicenter cohort study. by Lukundo Siame, Matenge Mutalange, Chitalu Chanda, Morgan Sakala, Chilala Cheelo, Kingsley Kamvuma, Geofrey Mupeta, Martin Chakulya, Memory Ngosa, Michelo Haluuma Miyoba, Situmbeko Liweleya, Sepiso K Masenga, Benson M Hamooya

“…<h4>Conclusions</h4>This study found a 2.3% incidence of kidney function impairment among PLHIV within 6 months of initiating ART. …”
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Comprehensive prognostic gene identification and functional characterization of GRAMD1A in Wilms tumor: development of risk prediction models and therapeutic implications by Qiang Zeng, Junfeng Tao, Lilu Qin, Yong Zeng, Zhong Liu, Mingxian Xu, Linshan Zeng

“…Identified differentially expressed genes (DEGs) underwent Gene Ontology (GO) and KEGG pathway enrichment analysis to explore biological functions and pathways associated with WT progression. …”
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Safety and effectiveness of non-invasive brain stimulation on mobility and balance function in children with cerebral palsy: a systematic review and meta-analysis by Mengru Zhong, Yage Zhang, Jie Luo, Tingting Chen, Jingbo Zhang, Tingting Peng, Mingshan Han, Wen Le, Tingting Peng, Kaishou Xu

“…Nevertheless, the safety and effectiveness of NIBS in children with CP remain uncertain and require further investigation. This study aimed to evaluate the safety and effectiveness of NIBS in improving mobility and balance function in children with CP. …”
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Preoperative Botulinum Toxin A and Its Impact on Pulmonary Function in Giant Abdominal Wall Hernias: A Prospective Spirometry-Based Analysis by Maciej Śmietański, Maciej Śmietański, Mateusz Zamkowski, Mateusz Zamkowski, Irmina Anna Śmietańska, Michał Putko, Orest Lerchuk, Andriy Porytsky, Zhanna Ushnevych, Volodymyr Khomyak

“…While the muscular and anatomical benefits of this approach are well documented, the potential effects on pulmonary function remain poorly studied, despite the involvement of the targeted muscles in the process of breathing.ObjectiveThis study aimed to evaluate the impact of botulinum toxin type A on respiratory system function, using spirometry to assess whether any observed changes reflect true improvement, mechanical compensation, or potential impairment.MethodsThis prospective, observational study included 37 patients with large abdominal wall hernias and a Loss of Domain component. …”
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Alterations of gray matter volume and functional connectivity in patients with cognitive impairment induced by occupational aluminum exposure: a case-control study by Huaxing Meng, Bo Liu, Xiaoting Lu, Yan Tan, Shanshan Wang, Baolong Pan, Hui Zhang, Qiao Niu

“…There was no significant difference in functional connectivity (FC) between the left caudate and the whole brain between the two groups. …”
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Functional improvement by tendon transfer for residual wrist dysfunction after botulinum therapy for severe upper limb spasticity: a case report by Takatoshi Hara, Yuta Miyazaki, Daisuke Nishida, Naho Takahashi, Keiko Sone, Yuki Hara, Ayano Matsui, Masahiro Abo

“…This case illustrates the critical role of tendon transfer surgery as a complementary intervention to overcome the limitations of conservative treatments, leading to substantial functional recovery. Future studies should aim to establish clear criteria for selecting candidates for tendon transfer surgery to ensure optimal functional outcomes for patients with severe spasticity.…”
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Comparative effects of square-stepping and strengthening exercises on cognitive and balance functions in chronic obstructive pulmonary disease: a randomized clinical trial by Alp Özel, Eylem Tütün Yümin, Suat Konuk

“…Square-stepping exercise (SSE), a structured multitasking intervention involving progressive, multi-directional step patterns, combines cognitive and motor challenges. This study aimed to compare the effects of SSE and traditional strengthening exercises (SE) on cognitive function and balance in individuals with COPD through a telerehabilitation model. …”
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