Upper Limb Evaluation in Duchenne Muscular Dystrophy: Fat-Water Quantification by MRI, Muscle Force and Function Define Endpoints for Clinical Trials. by Valeria Ricotti, Matthew R B Evans, Christopher D J Sinclair, Jordan W Butler, Deborah A Ridout, Jean-Yves Hogrel, Ahmed Emira, Jasper M Morrow, Mary M Reilly, Michael G Hanna, Robert L Janiczek, Paul M Matthews, Tarek A Yousry, Francesco Muntoni, John S Thornton

“…The aims of our study were to explore the responsiveness of upper-limb MRI muscle-fat measurement as a non-invasive objective endpoint for clinical trials in non-ambulant DMD, and to investigate the relationship of these MRI measures to those of muscle force and function.…”
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Efficacy of two doses of intra-articular ozone therapy for pain and functional mobility in knee osteoarthritis: a double-blind randomized trial by Zahra Arjmanddoust, Ahmad Nazari, Azar Moezy

“…Abstract Aim This double-blind, trial sought to assess the effectiveness of intra-articular ozone therapy at concentrations of 20 µg/mL and 40 µg/mL in managing pain and enhancing functional mobility in patients with knee osteoarthritis (KOA). …”
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Thyroid function test profile in patients who have thyroid nodule and its correlation with ultrasound TIRAD scoring system and cytological results by Sama Atta Gitti, Saman Sarko Baha Al-den

“…These nodules are mostly benign but remain a source of concern for both physicians and patients due to the possibility of malignant transformation. The aim of this study was to assess the ability and usefulness of thyroid function tests in predicting ultrasound and FNA outcomes of thyroid nodules and therefore confirm or rule out the malignant potential of these nodules. …”
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Graph theory analysis reveals functional brain network alterations in HIV-associated asymptomatic neurocognitive impairment in virally suppressed homosexual males by Xire Aili, Shuai Han, Juming Ma, Jiaojiao Liu, Wei Wang, Chuanke Hou, Xingyuan Jiang, Haixia Luo, Fan Xu, Ruili Li, Hongjun Li

“…Abstract Background This study aimed to investigate the global and nodal functional network alterations, abnormal connections of brain regions, and potential imaging biomarkers in virally suppressed people living with HIV (PLH) with asymptomatic neurocognitive impairment (ANI) using graph theory analysis. …”
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Predictive Value of Epicardial Adipose Tissue for Hemorrhagic Transformation and Functional Outcomes in Acute Ischemic Stroke Patients Undergoing Intravenous Thrombolysis Therapy by Liu L, Jia C, Xing C, Fu X, Liu Z, Ma A

“…Epicardial adipose tissue (EAT) contributes to the development of AIS and the disruption of the blood-brain barrier. This study aims to investigate the relationship between EAT and the risk of HT, as well as functional outcomes, in AIS patients treated with IVT.Patients and Methods: 230 AIS patients were included. …”
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Analysis of the Clinical Efficacy of Interlock Detachable Coil Interventional Embolization on Pelvic Congestion Syndrome and Ovarian Reserve Function: A Retrospective Study by Wang P, Zheng XL, Wang YH, Tao Y, Wang WC

“…Compared with free coil embolization, this combination can effectively increase vascular tension, reduce congestion, inhibit ovarian function, reduce pelvic congestion, and relieve symptoms.Keywords: endocrine hormone therapy, interventional embolization, interlock detachable coil, ovarian reserve function, pelvic congestion syndrome…”
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Relationship of the expression of calcium-handling proteins in the sarcoplasmic reticulum with polymorphic variants of their genes and with structural and functional parameters of... by D. S. Kondratieva, S. A. Afanasiev, E. F. Muslimova, E. A. Archakov, R. E. Batalov

“…Aim. To investigate the relationship between the expression of Ca2+ handling proteins of the sarcoplasmic reticulum, polymorphic variants of their genes, and structural and functional parameters of the heart in patients with atrial fibrillation (AF).Materials and methods. …”
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Influence of CuO nanoparticles on photosystem II structural stability and functional activity of corn (Zea mays L.) under drought stress by Shakeel Ahmad, Abdul Razzaq, Ismat Umar, Binish Khaliq, Muhammad Javed, Muhammad Iqbal

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A Cross-sectional Study to Assess the Association between the Cognitive Function with Severity of Dependence and Motivation to Quit in Patients with Substance Use Disorder by Shivani Dua, Ramchandra Das, Sudipta Kumar Das

“…This is because the individual’s motivation to quit is linked to their cognitive functioning. Aim: To assess the association between cognitive function, the severity of dependence, and the motivation to quit in patients with Substance Use Disorder (SUD). …”
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Relationship between an ageing measure and chronic obstructive pulmonary disease, lung function: a cross-sectional study of NHANES, 2007–2010 by Di Huang, Dan li, Zhishen Ruan, Minghao Liang, Yifei Xu, Zhanjun Qiu, Xianhai Chen

“…Phenotypic age (PhenoAge) is a new indicator of biological ageing, and phenotypic age minus actual age is known as phenotypic age acceleration (PhenoAgeAccel). This research aimed to analyse the relationship between PhenoAgeAccel and lung function and COPD.Design A cross-sectional study.Participants Data for the study were obtained from the National Health and Nutrition Examination Survey (NHANES) 2007–2010. …”
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Electroacupuncture Improves Cardiac Function via Inhibiting Sympathetic Remodeling Mediated by Promoting Macrophage M2 Polarization in Myocardial Infarction Mice by Rou Peng, Junjing Shi, Minjiao Jiang, Danying Qian, Yuhang Yan, Hua Bai, Meiling Yu, Xin Cao, Shuping Fu, Shengfeng Lu

“…However, the mechanism in how EA affects sympathetic remodeling and improves cardiac function remains unclear. The aim of this study is to investigate the cardioprotective mechanism of EA after myocardial ischemic injury by improving sympathetic remodeling and promoting macrophage M2 polarization. …”
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Effectiveness of transcutaneous electrical nerve stimulation in improving cognitive function in older adults with cognitive impairment: a systematic review and meta-analysis by Nga Huen Chan, Nga Huen Chan, Shamay S. M. Ng, Shamay S. M. Ng

“…This study aimed to evaluate the efficacy of TENS in improving cognitive function in older adults with cognitive impairment.MethodsA systematic search was performed in six electronic databases (CINAHL, Cochrane Library, Embase, Medline, PubMed, and Web of Science) to identify relevant studies published until May 2024. …”
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Hepatic and renal functions of paediatric patients with thalassaemia: a cross-sectional study from two large thalassaemia centres in Sri Lanka by Meranthi Fernando, Anuja Premawardhena, Sachith Mettananda, Hashan Pathiraja, Wasana Wijenayake, Raveen Thennakoon, Dayananda Bandara, Roshitha De Silva

“…Although the endocrine and cardiac complications of thalassaemia are well-studied, hepatic and renal complications are understudied. This study aims to describe the hepatic and renal functions and to understand their determinants among paediatric patients with β-thalassaemia.Design Cross-sectional study.Setting Two largest thalassaemia centres in Sri Lanka.Participants All haematologically confirmed patients with β-thalassaemia aged 1–16 years attending the study sites were recruited between 1 January and 31 March 2023. …”
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The effect of cognitive function and central nervous system depressant use on mortality-A prospective observational study of previously hospitalised older patients. by Tahreem Ghazal Siddiqui, Maria Torheim Bjelkarøy, Socheat Cheng, Espen Saxhaug Kristoffersen, Ramune Grambaite, Christofer Lundqvist

“…The long-term effects of CNSD use and reduced cognitive function in older patients are unclear. The aim of this study was to examine whether cognitive function and CNSD use at baseline hospitalisation were associated with all-cause mortality two years after discharge.…”
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Affective disorders: eliminate WArning signs and REstore functioning—AWARE—a randomised controlled multimodule intervention study, presentation of design and intervention by Maj Vinberg, Lars Vedel Kessing, Kamilla Woznica Miskowiak, Ida Seeberg, Rasmus Schwarz, Lone Decker

“…Consequently, the field needs new intervention strategies especially targeting patient groups with impaired functioning. This study aims to improve functioning and QoL in patients with affective disorders using a comprehensive 360° intervention.Methods and analysis Affective disorders: eliminate WArning signs And REstore (AWARE) functioning is a randomised, controlled, parallel-group design study. …”
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Effect of taking a dietary supplement containing Lactobacillus delbrueckii subsp. bulgaricus on clinical manifestations of functional dyspepsia and patients’ quality of life by I.G. Paliy, S.V. Zaika, O.O. Ksenchyn, I.V. Chernova

“…There is growing evidence that small intestinal microbiota plays a certain role in the pathophysiology of functional dyspepsia. Research aim: to study the effect of a product containing lyophilized lactic acid bacteria Lactobacillus delbrueckii subsp. bulgaricus strain 9702 (IMV B-7085) and its metabolic products on the clinical manifestations of the disease and quality of life of patients with functional dyspepsia. …”
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The effectiveness of neuromuscular electrical stimulation on pain, function, and quadriceps muscle strength in adults with patellofemoral pain: A systematic review and meta-analysi... by Ahmed Ibrahim Abdelhamed, Hossam Mortada, Ahmed Hendawy, Amr Elfeky, Roshdy M. Kamel, Shorouk Elshennawy

“…This systematic review aimed to evaluate the efficacy of adding NMES to exercise programs for treating PFP. …”
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Effectiveness of Combined Whole-Body Vibration and Intensive Therapeutic Exercise on Functional Capacity in Children with Cerebral Palsy: A Randomized Controlled Trial by Iñigo Monzón-Tobalina, Rosa María Ortiz-Gutiérrez, Ángela Concepción Álvarez-Melcón, Álvaro Pérez-Somarriba, Patricia Martín-Casas, María José Díaz-Arribas

“…This study aimed to evaluate the effectiveness of adding WBV to an intensive therapeutic exercise and functional training program in improving lower limb functional capacity in children with spastic CP. …”
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Conceptual foundations of a REFRAME-based approach to discriminate across total knee implant designs based on the positions of functional centres of rotation by Adrian Sauer, Ariana Ortigas-Vásquez, Christoph Thorwaechter, Peter E. Müller, Henning Windhagen, Allan Maas, Thomas M. Grupp, William R. Taylor, Matthias Woiczinski

“…Abstract In modern knee arthroplasty, surgeons increasingly aim for individualised implant selection based on data-driven decisions to improve patient satisfaction rates. …”
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Logistic function explains the growth dynamics of different types of shoots of four olive cultivars grown in a super high-density orchard by Leonardo Costanza, Diego Maria Pinto, Luigi Pinto, Gaetano Alessandro Vivaldi, Salvatore Camposeo

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