Whole Exome Sequencing Identifies a Novel Frameshift Mutation of the WRN Gene in a Werner Syndrome Family and Functional Analysis by Hao Xiong, Haiqing Gao, Jianji Wan, Jieping Xiao, Xiaoqun Luo, Xiuqin Dong, Yueheng Wu, Tao Liu

“…Conclusions This study identified a frameshift mutation in the WRN gene, which was associated with WS. The subsequent functional analysis revealed the inefficiency of the mutated protein. …”
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Effects of Medium- and Short-Chain Fatty Acids on Growth Performance, Nutrient Digestibility, Gut Microbiota and Immune Function in Weaned Piglets by Shuang Dong, Nan Zhang, Jihua Wang, Yu Cao, Lee J. Johnston, Yongxi Ma

“…The aim of this study was to investigate the combination effects of α-glycerol monolaurate (GML) and glyceryl tributyrate (TB) on growth performance, nutrient digestibility, gut microbiota, and immune function in weaned piglets. …”
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Trimester Specific Effect of Pregnancy on Maternal Cognitive Function using Critical Flicker Fusion Frequency: A Cross-sectional Study by J Roshni, S Anu, M Ramji

“…Introduction: Critical Flicker Fusion Frequency (CFFF) measures cognitive function by detecting the threshold at which flickering light appears steady. …”
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Predicting upper limb motor dysfunction after ischemic stroke: a functional near-infrared spectroscopy-based nomogram model by Menghui Liu, Chunxiao Wan, Chunyan Wang, Xinyi Li

“…BackgroundThis study aimed to identify independent risk factors associated with upper limb motor functional recovery in ischemic stroke patients 3 months post-stroke and to construct a predictive model based on functional near-infrared spectroscopy (fNIRS) data.MethodsThe study included 114 patients with ischemic stroke, divided into a training group (n = 80) and a validation group (n = 34). …”
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Acupuncture Alters Brain’s Dynamic Functional Network Connectivity in Stroke Patients with Motor Dysfunction: A Randomised Controlled Neuroimaging Trial by Yahui Wang, Mengxin Lu, Ruoyi Liu, Liping Wang, Yue Wang, Lingling Xu, Kang Wu, Chen Chen, Tianzhu Chen, Xinyue Shi, Kuangshi Li, Yihuai Zou

“…But its effect on dynamic brain networks remains unclear. This study is aimed at investigating how acupuncture affected the brain’s dynamic functional network connectivity (dFNC) after ischemic stroke. …”
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Association of the Systemic Inflammation Response Index with Functional Outcome in Acute Large Vessel Occlusion Stroke Patients Receiving Mechanical Thrombectomy by Wu W, Zhang YP, Qu XG, Zhang ZH

“…This study aimed to investigate the potential of SIRI as an innovative, inflammation-based predictor of 90-day functional outcome.Methods: This retrospective cohort study consecutively recruited 604 Chinese patients with diagnosed ALVOS who underwent MT at the First College of Clinical Medical Science of China Three Gorges University between July 2017 and April 2023. …”
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The mediating effect of sleep quality in the relationship between nocturia and psychosocial functions in nurses: a cross-sectional survey based on TARGET by Na Wei, Xinyue Zhang, Guanglin Liu, Youjuan Zhang, Li Li, Xiaoyan Lv, Yingjuan Cao

“…Given that nurses are particularly susceptible to nocturia due to frequent shift work, poor urination habits, and heavy workloads, this study aims to investigate the prevalence of nocturia among nurses and its effects on their psychosocial functions, as well as the mediating role of sleep quality. …”
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Pathogenetic assessment of external respiratory function disturbance and is interrelation with BDNF gene polymorphism in military servicemen in extreme conditions of the Arctic zon... by Lemeshchenko A.V., Gurina O.I., Makarov A.B., Berg D.V.

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Mid-Term Functional Recovery After ACDF and ACCF in the Treatment of Adjacent Two-Level Cervical Spondylosis: A Comparative Study by Wang X, Huang D, Han J, Luo J, Wang Y

“…Xinyang Wang, Dingan Huang, Jianbang Han, Junjie Luo, Yingfeng Wang Department of Spine Surgery, Peoples’ Hospital of Huangshan City, Huangshan, Anhui, 245000, People’s Republic of ChinaCorrespondence: Yingfeng Wang, Department of Spine Surgery, Peoples’ Hospital of Huangshan City, No. 4 Liyuan Road, Tunxi District, Huangshan, Anhui, 245000, People’s Republic of China, Email wxyang315@163.comObjective: This study aims to comparatively analyze the mid-term functional recovery following anterior cervical discectomy and fusion (ACDF) versus anterior cervical corpectomy and fusion (ACCF) in the treatment of adjacent two-level cervical spondylosis.Methods: A retrospective analysis was conducted on the medical records of 123 patients with adjacent two-level cervical spondylosis treated at our hospital between January 1, 2018, and June 30, 2022. …”
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Analysis of urban–rural differences in cognitive function among empty nest older adult in China based on Blinder-Oaxaca decomposition by Xiao Pan, Gui-Ning Zhang, Li-Chong Lai, Li-Yan Zhang, Hui-Qiao Huang

“…Among the differences in cognitive function among empty-nest older adult, 47.64% were related to the place of residence itself. …”
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Long‐Term Function Recovery Following Upper Versus Lower Lobectomy for Lung Cancer: A Multicenter Longitudinal Cohort Study by Xing Wei, Hongfan Yu, Bellinda King‐Kallimanis, Yangjun Liu, Lin Huang, Wei Dai, Ding Yang, Xiangxi Zhou, Qiang Li, Qiuling Shi

“…ABSTRACT Background The effects of lobectomy at various lung sites on postoperative function and recovery vary. This study aimed at assessing the long‐term impact of upper versus lower lobectomy on patients' postoperative daily function by analyzing patient‐reported outcomes. …”
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Exposure to urinary polycyclic aromatic hydrocarbon metabolites for the effect of lung function among children and adolescents: Epidemiological study and mechanism exploration by Bin Liu, Xue Zhao, Hongqi He, Linwei Zhou, Yuhan Fan, Xu Chai, Xin Xu, Xinjie Gong, Shuli An, Xiaodong Ling, Xia Chu

“…Human are widely exposed to polycyclic aromatic hydrocarbon (PAHs), but existing evidence about exposure to urinary PAHs metabolites for pulmonary health in children and adolescents is limited. Our aim was to examine the effect of single and mixed exposure of urinary PAHs metabolites on lung function among children and adolescents. …”
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Effect of Renal and Left Ventricular Function on Serial Pulmonary Arterial Pressure Changes after Device Closure of Atrial Septal Defect by Chul Shin, Young Won Yoon, In-Soo Kim, Jong-Youn Kim, Pil-Ki Min, Byoung Kwon Lee, Bum-Kee Hong, Se-Joong Rim, Hyuck Moon Kwon, Eui-Young Choi

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Neural Compensatory Response During Complex Cognitive Function Tasks in Mild Cognitive Impairment: A Near-Infrared Spectroscopy Study by Jin A. Yoon, In Joo Kong, JongKwan Choi, Ji Yeong Baek, Eun Joo Kim, Yong-Il Shin, Myoug-Hwan Ko, Yong Beom Shin, Myung Jun Shin

“…The present pilot study was aimed at conducting a comparative analysis of the level of activation in the prefrontal cortex among a normal elderly group and amnestic and nonamnestic mild cognitive impairment (MCI) groups and investigating the presence of neural compensatory mechanisms according to types of MCI and different cognitive tasks. …”
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Executive Functions Assessment Based on Wireless EEG and 3D Gait Analysis During Dual-Task: A Feasibility Study by Pasquale Arpaia, Renato Cuocolo, Allegra Fullin, Ludovica Gargiulo, Francesca Mancino, Nicola Moccaldi, Ersilia Vallefuoco, Paolo De Blasiis

“…Executive functions (EFs) are neurocognitive processes planning and regulating daily life actions. …”
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Study of the Functional State of the Proximal Renal Tubules in Patients with Asymptomatic Chronic Heart Failure in Dyslipidemia and its Correction with Simvastatin Treatment by V. Yu. Kopylov

“…The exclusion criterion was a violation of the filtration capacity of the kidneys and the presence of gross dysfunction of organs and systems of the body. The functional state of the proximal renal tubules was assessed by the concentration of NAG and LAAP in dialized urine.Results. …”
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Changes in Respiratory Function Before and After Cardiopulmonary Bypass in Children with Congenital Heart Disease with Increased or Decreased Pulmonary Blood Flow by Liang L, Hou A, Xi H, Yang J, Liu C

“…Lijun Liang,1 Ang Hou,1 Hongwei Xi,2 Jinming Yang,1 Caixia Liu1 1Department of Cardiothoracic Surgery, Shanxi Children’s Hospital, Shanxi Women and Children Hospital, Taiyuan, Shanxi Province, 030025, People’s Republic of China; 2Department of General Surgery, Shanxi Children’s Hospital, Shanxi Women and Children Hospital, Taiyuan, Shanxi Province, 030025, People’s Republic of ChinaCorrespondence: Jinming Yang, Department of Cardiothoracic surgery, Shanxi Children’s Hospital, Shanxi Women and Children Hospital, No. 65 of Jinxi Street, Jinyuan District, Taiyuan, Shanxi Province, 030025, People’s Republic of China, Tel +8613453460527, Email jinmingyang_yjm@126.com Caixia Liu, Department of Cardiothoracic surgery, Shanxi Children’s Hospital, Shanxi Women and Children Hospital, No. 65 of Jinxi Street, Jinyuan District, Taiyuan, Shanxi Province, 030025, People’s Republic of China, Tel +8618634355391, Email liucaixialllcx@126.ocmObjective: Cardiopulmonary bypass (CPB) is a fundamental approach for managing complex congenital heart diseases (CHD). This study aims to examine the changes in respiratory function before and after CPB in children under 12 years diagnosed with CHD with different types of shunts.Methods: A retrospective analysis was conducted on the clinical data of 60 pediatric patients with CHD admitted to the hospital between January 2022 and December 2023. …”
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Influence of matrix nature on the functional efficacy of biomedical cell product for the regeneration of damaged liver (experimental model of acute liver failure) by S. V. Gautier, M. Yu. Shagidulin, N. A. Onishchenko, I. M. Iljinsky, V. I. Sevastianov

“…Aim. A comparative analysis of the functional efficacy of biomedical cell products (BMCP) for the regeneration of damaged liver based on biopolymer scaffolded porous and hydrogel matrices was performed on the experimental model of acute liver failure. …”
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Mapping neutron biological effectiveness for DNA damage induction as a function of incident energy and depth in a human sized phantom by Alice Mentana, Virgilio Quaresima, Pavel Kundrát, Isabella Guardamagna, Leonardo Lonati, Ombretta Iaria, Andrea Previtali, Giorgia Santi Amantini, Luca Lunati, Virginia Boretti, Livio Narici, Luca Di Fino, Luca Bocchini, Claudio Cipriani, Giorgio Baiocco

“…RBE is evaluated as a function of the incident neutron energy and of the depth inside a human-sized reference spherical phantom. …”
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Does Deltoid Ligament Repair Reduce Complications and Improve Functional Outcomes Measured by PROMIS Scores Following Ankle Fracture Surgery? by Steven M. Hadley BA, Rachel Bergman MD, John J. Peabody MD, Sarah J. Westvold MPH, Ryan Filler MD, Milap Patel DO, Anish R. Kadakia MD

“…Background: Deltoid repair (DR) in ankle fracture surgery remains controversial. This study aims to determine whether DR reduces complications and improves outcomes measured by Patient Reported Outcomes Measurement Information System (PROMIS) computerized adaptive tests (CATs) of physical function (PF) and pain interference (PI). …”
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