Functional analysis of two PLA2G2A variants associated with secretory phospholipase A2-IIA levels. by Holly J Exeter, Lasse Folkersen, Jutta Palmen, Anders Franco-Cereceda, Jackie A Cooper, Anastasia Z Kalea, Ferdinand Van't Hooft, Per Eriksson, Steve E Humphries, Philippa J Talmud

“…The protein is encoded by the PLA2G2A gene and the aim of this study was to test the functionality of two PLA2G2A non-coding SNPs, rs11573156 C>G and rs3767221 T>G where the rare alleles have been previously associated with higher and lower sPLA2-IIA levels respectively.…”
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Double‐blind, randomized, 8‐week multicenter study of the efficacy and safety of STW 5‐II versus placebo in functional dyspepsia by Bettina Vinson, Careen Fink, Manfred Wargenau, Nicholas J Talley, Gerald Holtmann

“…We evaluated the efficacy and safety of 8 weeks of treatment with the herbal combination product STW 5‐II for patients with functional dyspepsia (FD) meeting Rome II criteria. …”
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Effectiveness of Modified Holmich Protocol on strength, functional performance and injury prevention of groin injuries among U‑19 female footballers by Riya Gupta, Aditi Singh, Anu Bansal

“…Abstract Background Adductor-related groin pain syndrome is the most common problem for athletes in many sports which often significantly reduces athletic performance and activity. Objective This study aimed to investigate the effectiveness of the Modified Holmich protocol on hip adductor strength, functional performance, and injury prevention in U-19 female footballers with groin discomfort. …”
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Association between impairment of lung function and risk of anxiety and depression in patients with chronic obstructive pulmonary disease—a systematic review by Johanne Hermann Karlsen, Kirstine Hermann Jørgensen, Ulla Møller Weinreich

“…Abstract Background This systematic review aims to examine the association between impairment of lung function and risk of anxiety and depression, respectively, in patients with chronic obstructive pulmonary disease (COPD). …”
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Quality of life and parental stress related to executive functioning, sensory processing, and activities of daily living in children and adolescents with neurodevelopmental disorde... by Vanesa Lobato-Ruiz, Dulce Romero-Ayuso, Abel Toledano-González, José Matías Triviño-Juárez

“…Parental stress also affects family dynamics and QoL due to the additional demands of care, particularly focusing on the management of activities of daily living (ADLs). This study aimed to analyze the relationship between parents’ QoL and stress, involving 46 parents of children aged 3 to 12 years with neurodevelopmental disorders, while also examining the relationship with the performance in ADLs, sensory processing, and executive functioning of children with neurodevelopmental disorders. …”
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Quality of life and objective functional impairment in lumbar spinal stenosis: a protocol for a systematic review and meta-analysis of moderators by Andrea Pozza, Fabio Ferretti, Anna Coluccia, Roberto Gusinu, Giacomo Gualtieri, Vitaliano Francesco Muzii

“…Moderators will be investigated through meta-regression.Conclusions A summary of the evidence on quality of life and functional impairment in LSS may suggest clinical and occupational health medicine strategies aimed to timely detect and prevent these outcomes. …”
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How achievement of a stroke care pathway is associated with functional outcome after stroke: a national, register-based study by Elin Bergh, Torunn Askim, Ole Morten Rønning, Stian Lydersen, Hild Fjaertoft, Bente Thommessen

“…In the present study, we aimed to evaluate whether the achievement of key objectives within the recently implemented Norwegian stroke care pathway (SCP) was associated with functional outcome 3 months after stroke and to identify the characteristics of patients who achieved the recommended goals. …”
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Gait instability is a more specific predictor of corticospinal tract function than gait speed in clinically stable multiple sclerosis by Furkan Bilek, Arthur R. Chaves, Oleksandr Fesenko, Michelle Ploughman

“…Although gait speed, as measured using the Timed 25 Foot Walk Test, is used clinically to track MS progression, it is less useful in people with MS who do not have overt gait impairment. This study aimed to identify specific spatiotemporal gait parameters that predict corticospinal tract (CST) function in individuals with MS. …”
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The Short-Term Effect of Stent Size and Number on Left Ventricular Systolic Function Improvement After Elective Percutaneous Coronary Intervention by Sh. Mostafa, O. Sanad, M. Shawky, M. Magdy, E. Elkeshk

“…The effect of stent size and number on left ventricular systolic function improvement after percutaneous coronary intervention (PCI) using drug eluting stent is not clear enough.Aim. …”
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Effect of continuous theta burst stimulation on the glymphatic system, brain network and cognitive function in patients with cerebral small vessel disease by Pei Dai, Hui-xian Yu, Zhao-xia Wang, Si-hao Liu, Chang-bin Liu, Guang-qing Xu

“…ObjectiveWe aim to investigate the impact of continuous theta burst stimulation (cTBS) on glymphatic system (GS), brain network (BN) and cognition in cerebral small vessel disease (CSVD).MethodsThis exploratory study included a small cohort of 11 patients, divided into a cTBS group (6 patients) and a sham-cTBS group (5 patients). …”
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Paroxysmal Atrial Fibrillation during Spasm Provocation Test with Acetylcholine: Clinical Characteristics of Patients and Effect on Coronary Microvascular Function Measurements by Hiroki Teragawa, Chikage Oshita, Yu Hashimoto, Shuichi Nomura

“…Furthermore, the association of AF with the outcome of the coronary microvascular function test (CMFT) is unknown. This study aimed to evaluate whether patients with angina with non-obstructive coronary artery disease (ANOCA) who developed AF during SPT with ACh had any clinical characteristics. …”
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INFLUENCE OF CHRONIC NEUROGENIC PAIN ON THE DYNAMICS OF THE NO-SYSTEM FUNCTIONING DURING MELANOMA B16/F10 GROWTH IN MALE MICE by O. I. Kit, I. M. Kotieva, E. M. Frantsiyants, E. I. Surikova, I. V. Kaplieva, V. A. Bandovkina, L. K. Trepitaki, I. V. Neskubina, Ju. A. Pogorelova

“…Male mice with B16 melanoma growing in the presence of cnp demonstrated a more active functioning of the no-system already from week 1, compared to standard tumor growth, which might result in a greater rate of growth of melanoma with cnp. …”
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Evaluation of the functional state of mitochondria isolated from mononuclear leukocytes by flow cytometry in patients with chronic heart failure receiving ubidecarenone by O. A. Lobanova, L. B. Gaikovaya, V. A. Dadali, A. I. Ermakov, G. A. Kukharchik

“…Aim. To evaluate the functional state of mitochondria isolated from peripheral blood mononuclear leukocytes using flow cytometry in patients with chronic heart failure receiving ubidecarenone (coenzyme Q).Materials and methods. …”
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Androgen receptor gene CAG-trinucleotide repeat length affects function of endothelium in men with hypogonadism and type 2 diabetes mellitus by I. A. Khripun, R. S. Ismailov, I. I. Belousov, Kh. S. Ibishev, M. I. Kogan

“…The influence of the length of the number of CAG repeats in the androgen receptor gene (nCAG AR) on endothelial dysfunction (EnD) is currently understudied.Objective. The study aimed to evaluate the relationship between the nCAG AR and the dynamics of biochemical and ultrasound markers of EnD in men with functional hypogonadism and type 2 diabetes mellitus (T2DM) receiving testosterone replacement therapy (TRT).Materials & methods. …”
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Pan‐Immune‐Inflammation Value Predicts 3‐Month Functional Outcomes in Patients With Acute Ischemic Stroke Treated With Mechanical Thrombectomy by Meltem Karacan Gölen, Keziban Uçar Karabulut, Muhammed Kamiloğlu, Aynur Yonar

“…Severity of stroke was assessed using the National Institute of Health Stroke Scale (NIHSS) scores on admission. Poor 3‐month functional outcome was defined as Modified Rankin Scale (mRS) scores of >2. …”
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Improvement of persistent impairments in executive functions and attention following electroconvulsive therapy in a case control longitudinal follow up study by Åsa Hammar, Eivind Haga Ronold, Malene Alden Spurkeland, Rita Ueland, Ute Kessler, Ketil J. Oedegaard, Leif Oltedal

“…The development and etiology of neurocognitive impairment in MDD were examined by investigating the cognitive profile following ECT related to the state, scar, and trait perspectives, with the former predicting improvements parallel with depressive symptoms, while the two latter expected persisting impairments. Executive functions (EF) and attention are central to cognition and alterations in these functions could influence other domains like memory. …”
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Application of the Monaco-serial biological function for cardiac dose constraints in DIBH-IMRT treatment planning for left-sided breast cancer by Haili Hu, Haili Hu, Zhou Jueyi, Jiang Hao, Jianjun Lai, Jianjun Lai

“…BackgroundThe Serial function in the Monaco treatment planning system is essential for cardiac dose optimization in left breast cancer radiotherapy; however its optimal K-value for deep-inspiration breath-hold intensity-modulated radiotherapy (DIBH-IMRT) has not been established. …”
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The interrelationships between the microRNA miR-34a and the plant flavonoids apigenin and quercetin in the regulation of ovarian cell functions by Alexander V. Sirotkin, Zuzana Fabová, Barbora Loncová, Zuzana Kislíková, Abdel Halim Harrath

“…Abstract Our study aimed to examine the possible interrelationships between RNA interference and plant flavonoids in the regulation of ovarian functions. …”
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Formulation and phytochemical analysis of a potentially functional beverage from combining a leaf extract and pulp of Annona muricata (Annonaceae) by Yolanda Nolasco-González, María de Lourdes García-Magaña, Andrés Eloy León-Fernández, Juan L. Monribot-Villanueva, José A. Guerrero-Analco, Efigenia Montalvo González

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The effects of mediterranean and Persian diet on sexual function and semen parameters quality among infertile men: a randomized controlled trial by Ali Ghasemi, Amir Mohammad Jaladat, Mohammad Hossein Sharifi, Ali Tavakoli, Haleh Ghaem, Abdolreza Haghpanah

“…Abstract There is no consensus on which diet best for improving male reproductive health and published studies on the effect of diet on sexual function and semen quality are limited. The aim of this study was to investigate the effect of intervention based diet, namely Persian Medicine Diet (PMD) and Mediterranean Diet (MD), on sexual function and semen quality parameters. …”
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