PEG-functionalized UiO-66 MOFs for targeted vincristine delivery: enhanced cytotoxicity in breast and ovarian cancer cell lines by Zahra Sadeghi Jam, Farzaneh Tafvizi, Parvin Khodarahmi, Parvaneh Jafari, Fahimeh Baghbani-Arani

“…Abstract Vincristine (VIN) inhibits microtubule formation in the mitotic spindle, effectively arresting cells in mitosis. This study aimed to develop a polyethylene glycol (PEG)-functionalized UiO-66 metal–organic framework (MOF) as a targeted drug delivery system for VIN in MDA-MB-231 (breast cancer) and A2780 (ovarian cancer) cell lines. …”
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Premenstrual syndrome and premenstrual dysphoric disorder: Symptoms severity, functional impairment, and associated factors: A Saudi cross-sectional study by Samiha Hamdi Sayed, Mohammed AL-Mohaithef, Enas Mohamed Ibrahim, Ebtesam A. Elsayed

“…BACKGROUND: Premenstrual syndrome (PMS) is a considerable health problem among women that negatively impacts their functionality and productivity. Thus, this study aims to assess PMS and premenstrual dysphoric disorder (PMDD) symptoms severity, functional impairment, and associated factors in Saudi Arabia. …”
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Isokinetic Training Program to Improve the Physical Function and Muscular Performance of an Individual with Partial Injury of the Medial Meniscus: A Case Report by Karen Obara, Pedro Silva, Mariana Silva, Fagner Mendes, Gabriel Santiago, Ihan Oliveira, Jefferson Cardoso

“…# Background and Purpose One of the best alternatives for the treatment of meniscal injuries in relation to surgical procedures, is exercise. This case report aimed to describe the effects of isokinetic training and a neuromuscular/proprioceptive exercise program on muscle performance and physical function in an individual after a rupture of the posterior horn of the medial meniscus…”
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The impact of Toll-like receptors on the immune system functioning and on the immunopathogenesis of chronic hepatitis C: a modern view (literature review) by L. M. Syzova, T. I. Koval, V. I. Ilchenko, I. M. Zviaholska, О. M. Iziumska

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The Effect of Enhanced External Counterpulsation Therapy and Improvement of Functional Capacity in Chronic Heart Failure patients: a Randomized Clinical Trial by Starry H Rampengan, Joedo Prihartono, Minarma Siagian, Suzanna Immanuel

“… Aim: to investigate the efficacy of enhanced external counterpulsation (EECP) therapy to improve functional capacity in patients with chronic heart failure (CHF). …”
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IGFBP2 Modulates Trophoblast Function and Epithelial–Mesenchymal Transition in Preeclampsia via the PI3K/AKT Signaling Pathway by Shengping Meng, Yanping Qin, Chunyan Lyu, Sumei Wang

“…Moreover, the gain- and loss-of-function assays were conducted in human trophoblast cell line HTR-8/SVneo, and cellular models exhibiting overexpression and the knockdown of IGFBP2 were established. …”
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Effect of Leap Motion-based 3D Immersive Virtual Reality Usage on Upper Extremity Function in Ischemic Stroke Patients by Muhammed Nur ÖGÜN, Ramazan KURUL, Mustafa Fatih YAŞAR, Sule Aydin TURKOGLU, Şebnem AVCI, Nebil YILDIZ

“…ABSTRACT Immersive virtual reality (VR) is a technology that provides a more realistic environmental design and object tracking than ordinary VR. The aim of this study was to investigate the effectiveness of immersive VR on upper extremity function in patients with ischemic stroke. …”
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An explanatory model of suicidal ideation based on family functionality and mental health problems: A cross-sectional study of medical students by Leslie Aguilar-Sigueñas, David Villarreal-Zegarra

“…Background: One of the mental health problems with the greatest impact on people's lives is suicidal behavior, a largely preventable public health problem that accounts for almost half of all violent deaths. The aim of the study is to propose a model that can explain and predict suicidal ideation based on mental health problems (stress-anxiety-depression) and family functionality (cohesion, flexibility, and cohesion). …”
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USE OF A NUMERICAL ANALYTICAL MODEL FOR ASSESSING THE FUNCTIONAL EFFECTIVENESS OF AN INFORMATION PROTECTION SYSTEM BY ANALYSING ITS PROBABILISTIC-TEMPORAL CHARACTERISTICS by V. P. Alferov, A. V. Butskikh, A. V. Krisilov, A. D. Popov, E. A. Rogozin

“…Abstract. Aim Currently, the implementation of computational experiments to determine the probabilistic-temporal characteristics of protection functions for automated information systems is a complex and costly task. …”
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Small world properties of schizophrenia and OCD patients derived from fNIRS based functional brain network connectivity metrics by Ata Akın, Emre Yorgancıgil, Ozan Cem Öztürk, Bernis Sütçübaşı, Ceyhun Kırımlı, Elçim Elgün Kırımlı, Seda Nilgün Dumlu, Gülnaz Yükselen, S. Burcu Erdoğan

“…A healthy brain at rest is known to exhibit small-world features with high clustering coefficients and shorter path lengths in contrast to random networks. The aim of this study was to compare the small-world properties of prefrontal cortical functional networks of healthy subjects with OCD and SCZ patient groups by use of hemodynamic data obtained with functional near infrared spectroscopy (fNIRS). 13 healthy subjects and 47 patients who were clinically diagnosed with either OCD (N = 21) or SCZ (N = 26) completed a Stroop test while their prefrontal cortex (PFC) hemodynamics were monitored with fNIRS. …”
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Leaf functional metabolic traits reveal the adaptation strategies of larch trees along the R/B ratio gradient at the stand level by Xiaoqian Song, Zhonghua Zhang, Haiyan Huang, Xin Guan, Lu Jin, Yu Shi, Wenjie Wang, Zhonghua Tang

“…Abstract Light is crucial for understory sapling regeneration, and understanding leaf functional traits (LFT) is key to saplings’ adaptation to different light conditions. …”
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Sleep deprivation disturbed regional brain activity in healthy subjects: evidence from a functional magnetic resonance-imaging study by Wang L, Chen Y, Yao Y, Pan Y, Sun Y

“…Mean ALFF of the dorsolateral prefrontal cortex showed a significant positive correlation with response time (r=0.675, P=0.016).Conclusion: SD disturbed the regional brain activity of the default-mode network, its anticorrelated “task-positive” network, and the advanced cognitive function brain areas. Keywords: sleep deprivation, amplitude of low-frequency fluctuation, default-mode network, functional magnetic resonance imaging…”
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Associated Mirror Therapy Enhances Motor Recovery of the Upper Extremity and Daily Function after Stroke: A Randomized Control Study by Jin-Yang Zhuang, Li Ding, Bei-Bei Shu, Dan Chen, Jie Jia

“…Bimanual cooperation plays a vital role in functions of the upper extremity and daily activities. …”
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Functional capacity testing in patients with pulmonary hypertension (PH) using the one-minute sit-to-stand test (1-min STST). by Christina Kronberger, Roya Anahita Mousavi, Begüm Öztürk, Robin Willixhofer, Theresa-Marie Dachs, René Rettl, Luciana Camuz-Ligios, Nima Rassoulpour, Christoph Krall, Brigitte Litschauer, Roza Badr Eslam

“…<h4>Background</h4>The one-minute sit-to-stand-test (1-min STST) is a quick, space saving test to evaluate functional capacity. Exercise testing plays an important role in the long-term follow-up of pulmonary hypertension (PH) patients and is currently evaluated using the six-minute-walk-test (6MWT). …”
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Isokinetic assessment of muscle function according to physical activity level and cardiovascular risk in asymptomatic adults aged 20 to 80 years by V.Z. Dourado, M.B. Nascimento, R.C. Navarro, R.P. da Silva, B.B. Gonze, K.M. Guedes, V.T. Lauria, W.O. Vieira, T.L.V.D.P. Ostolin

“…We aimed to describe the percentiles of normality of the isokinetic muscle function of the knee and elbow joints. …”
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ASSESSMENT OF SITAGLIPTIN INFLUENCE ON ARTERIAL WALL STIFFNESS, RENAL FUNCTION AND RENAL CIRCULATION IN CARDIOVSCULAR PATIENTS WITH DECOMPENSATED TYPE 2 DIABETES by E. V. Oskola, A. T. Shubina, A. R. Zairova, M. V. Andreevskaya, R. M. Bogieva, M. G. Bolotina, A. N. Rogoza, Yu. A. Karpov

“…Aim. To study dynamics of stiffness parameters in various type arteries, renal function and renal circulation in arterial hypertension (AH) and ischemic heart disease (CHD ) with decompensated 2 type diabetes mellitus (DM2) on the sitagliptin therapy during 24 weeks.Material and methods. …”
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Arthroscopic anterior cruciate ligament reconstruction: Comparison of functional outcome between femoral fixations by suspensory fixation versus aperture fixation by Las Jamal Khorsheed, Areewan Muhammed Saeed, Ziyad Serdar Ali, Aryan Jaza Hama Salih

“…The use of a hamstring tendon autograft has become a common choice among orthopedic surgeons because of less donor site problem. The aim of this study is to compare the functional outcome between suspensory fixation and aperture fixation of arthroscopic anterior cruciate ligament reconstruction. …”
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Using X-ray velocimetry to measure lung function and assess the efficacy of a pseudomonas aeruginosa bacteriophage therapy for cystic fibrosis by Stephanie A. Harker, Melissa Preissner, Rachel Yoon Chang, David Trevascus, Chengxi Liu, Yuncheng Wang, Michael Y. T. Chow, Patricia Cmielewski, Nicole Reyne, Ying Ying How, James A. Pollock, Mitzi Klein, Christopher A. Wright, Stephen Dubsky, Martin Donnelley, Hak-Kim Chan, Kaye S. Morgan

“…Current efficacy assessment in animal models is highly invasive, typically requiring histological assessment. We aim to use XV techniques as non-invasive alternatives to demonstrate efficacy of bacteriophage therapy for treating Pseudomonas aeruginosa CF lung infections, measuring functional changes post-treatment. …”
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Prioritisation of functional needs for ICU intelligent robots in China: a consensus study based on the national survey and nominal group technique by Hao Wang, Ying Bai, Fan Zhang, Shuya Wang, Zhen Cui, Xin Yuan, Liu Zhang, Xinbao Wu, Yufeng Yan, Miaomiao Yu, Bo Ouyang

“…Objective This study aims to define the prioritisation of the needs for an intelligent robot’s functions in the intensive care unit (ICU) from a clinical perspective.Design This study introduces a nominal group technique.Setting This study uses national setting.Participants This study includes a total of 851 respondents from 34 provinces in China who participated in the survey. …”
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Spontaneous neural activity alterations in medication-naïve primary blepharospasm: a resting-state functional magnetic resonance imaging study by Hua-Liang Li, Shu Wang, Xin-Xin Yao, Si-Yu Gu, Jian-Bin Hu, Ping-Lei Pan, Ping-Lei Pan

“…This study aimed to add to the increasing knowledge by examining abnormalities in local spontaneous neural activity in this disorder.MethodsResting-state functional magnetic resonance imaging data were acquired from 32 medication-naïve patients with BSP and 32 age- and sex-matched healthy controls in this study. …”
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