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5161
Abnormal spontaneous regional brain activity in primary insomnia: a resting-state functional magnetic resonance imaging study
Published 2016-06-01“…Thus, the current study aimed to investigate functional specialization of PI using resting-state fMRI with amplitude of low frequency fluctuations (ALFFs) algorithm. …”
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5162
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5163
Dual functions of silibinin in attenuating aortic dissection via regulating iron homeostasis and endoplasmic reticulum stress against ferroptosis
Published 2024-12-01“…SIL treatment enhanced cell viability and mitochondrial function while reducing reactive oxygen species (ROS) generation and mitigating ferroptosis in primary human aortic smooth muscle cells (HASMCs) induced by RSL3 or IKE. …”
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5164
Correlation of the severity of the clinical presentation of SARS-CoV-2 pneumonia with respiratory function parameters in the post-COVID period
Published 2024-09-01“…The most prevalent symptoms are respiratory ones. This study aimed to present the correlation between the severity of the clinical presentation of the disease and the results of respiratory function tests conducted within 6 months after hospital discharge. …”
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5165
From Metagenomes to Functional Expression of Resistance: <i>floR</i> Gene Diversity in Bacteria from Salmon Farms
Published 2025-01-01“…Total DNA from bacterial communities was used as a template to recover <i>floR</i> gene variants, which were tested by heterologous expression and functional characterization of phenicol resistance. …”
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5166
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5167
A decline in renal function is associated with a reduction in myocardial mechano-energetic efficiency in individuals at high cardiometabolic risk
Published 2025-08-01“…Conclusions Our findings demonstrate that a consistent reduction in renal function across eGFR categories is independently associated with reduced myocardial MEEi in individuals with high cardiometabolic risk suggesting that even a mild decline in nearly normal renal function may contribute to altered myocardial energetics.…”
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5168
Trail Running vs. Adequate Physical Activity on Physical Fitness, Vascular Function, and Cognition in Middle-Aged Office Workers
Published 2025-05-01“…This information is particularly important for office workers who tend to remain sedentary during working hours. Aim: To evaluate a variety of health-related physical fitness, peripheral and cerebral vascular function, and cognition of middle-aged male office workers who had been regularly performing adequate physical activity or trail running. …”
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5169
Executive function at baseline and follow-up in opioid maintenance patients and its relation to psychiatric comorbidity and substance use patterns
Published 2025-04-01“…This study aimed to assess executive function in patients with opioid use disorder at treatment initiation and one-year follow-up, exploring its correlation with psychiatric comorbidity within the patient group. …”
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5170
Functional cortical changes in relapsing-remitting multiple sclerosis at amplitude configuration: a resting-state fMRI study
Published 2016-11-01“…Keywords: multiple sclerosis, amplitude of low-frequency fluctuation, receiver operating characteristic, functional magnetic resonance imaging, blood oxygen level dependent, resting state…”
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5171
Harnessing microalgae as a bioresource for nutraceuticals: advancing bioactive compound exploration and shaping the future of health and functional food innovation
Published 2025-04-01“…They have shown impressive health benefits due to their antioxidant, anti-inflammatory, antimicrobial, and anticancer properties, making them valuable for developing medicines, functional foods, and dietary supplements. Advances in technology, such as improved bioreactor systems, genetic engineering, and metabolic fine-tuning, have made it easier to grow microalgae and increase the production of beneficial compounds. …”
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5172
Ratio and interconnections of functional fitness structure key components of elite combat athletes at the stage of maximum realization of individual capabilities
Published 2020-10-01“…Background and Study Aim. The objective of the work consisted in studying the ratio and interconnections of functional fitness structure key components of elite combat athletes in the process of adaptation to physical loads at the stage of individual capacity maximum realization. …”
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5173
Effects of Functional Partial Body Weight Support Treadmill Training on Mobility in Children with Ataxia: A Randomized Controlled Trial
Published 2025-04-01“…The aim of this study is to assess the effectiveness of an intensive program of Functional Partial Body Weight Support Treadmill Training (FPBWSTT) on the mobility and functionality of children with ataxia. …”
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5174
Urinary Fetuin-A with Specific Post-Translational Modification in Type 1 Diabetes Patients with Normoalbuminuria and Preserved Kidney Function
Published 2025-02-01“…Above- and below-median-eGFR groups were considered as having normal and declining kidney function, respectively. <b>Results</b>: The median (IQR) uPTM3-FetA level was 11.7 (8.43–16.65 µg/24 h), with no significant difference between males and females, as well as normal and declining kidney function patients. …”
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5175
An expanded polyglutamine in ATAXIN1 results in a loss-of-function that exacerbates severity of Multiple Sclerosis in an EAE mouse model
Published 2025-04-01“…Understanding the functional role of ATXN1 in MS pathogenesis may open new avenues for therapeutic strategies aimed at mitigating disease progression.…”
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5176
Adaptation of the Upper Limb Functional Index (ULFI) to a Polish version and validation in patients with upper limb musculoskeletal disorders
Published 2025-05-01“…Abstract Background The Upper Limb Functional Index (ULFI) is a robust, widely used tool for assessing the functional status of the upper limbs (ULs) and the effectiveness of interventions in patients with musculoskeletal disorders (MSDs). …”
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5177
Integrating functional and techno-economic analyses to optimize black bean protein extraction: a holistic framework for process development
Published 2025-01-01“…This study aimed to develop aqueous (AEP) and enzyme-assisted extraction processes (EAEP) for black bean proteins using an optimization framework that integrates functionality and industrial-scale profitability. …”
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5178
Characterization of gut microbiota and metabolites in renal transplant recipients during COVID-19 and prediction of one-year allograft function
Published 2025-04-01“…GEE further identified 12 genera and 181 metabolites closely associated with these trajectories; a multivariable model incorporating gut metabolites of 1-Caffeoylquinic Acid and PMK was found to effectively predict one-year allograft function. Conclusions Our study indicates a possible interaction between the composition of the gut microbiota and metabolites community and COVID-19 in renal transplant recipients, particularly in relation to disease severity and the prediction of one-year allograft function.…”
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5179
The efficacy and safety of auricular acupoint therapy on treating functional dyspepsia with insomnia: study protocol for a randomized controlled trial
Published 2025-03-01“…BackgroundFunctional dyspepsia (FD) is a prevalent health issue currently lacking optimal treatment options, with its global incidence rate increasing in recent years. …”
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5180
Upcycling defatted rice bran into alginate based noodles via hydrocolloid assisted development and assessment of structural and functional properties
Published 2025-01-01“…Despite its nutritional potential, its coarse texture, low stability, and poor compatibility with food systems limit its direct application. This study aimed to valorize DRB by formulating functional noodles using alginate-based encapsulation and to investigate the effects of different hydrocolloids including gelatin, carrageenan, and agar on noodle structure, texture, in vitro digestion, and phenolic release. …”
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