Assessment of photoreceptor recovery and visual function utilizing adaptive optics and microperimetry in patients with surgically closed macular holes by Yuanyuan Liu, Xueli Yang, Wei Zhou, Jinguo Yu, Song Chen, Tiangeng He, Caiyun You, Xiangda Meng, Mengyu Liao, Yi Lei, Hua Yan

“…Background: This study investigated the association between photoreceptor structural restoration and visual function outcomes in patients undergoing surgery for closed macular holes (MHs). …”
Get full text

Evaluation of Sensory and Motor Function in Spinal and Bulbar Muscular Atrophy Using Quiet Stance and Reactive Postural Control by Joseph A. Shrader, Ashwini Sansare, Allison C. Niemic, Rafael Jiménez-Silva, Joshua G. Woolstenhulme, Galen O. Joe, Uma Jacobs, Angela Kokkinis, Kenneth Fischbeck, Chris Grunseich, Cris Zampieri

Get full text

THE INFLUENCE OF HEART RATE VARIABILITY ON CLINICAL COURSE OF CHRONIC HEART FAILURE AND RENAL FUNCTION IN ATRIAL FIBRILLATION PATIENTS by E. A. Polyanskaya, S. V. Mironova, N. A. Koziolova

“…Aim. Evaluation of structural and functional condition of the left ventricle (LV) and kidneys in permanent atrial fibrillation patients (AF) with ischemic chronic heart failure (CHF) according to mean 24 hour heart rate and heart rate variability.Material and methods. …”
Get full text

Newly Isolated Priestia megaterium LAMA1607 for Enhanced Biological Phosphorus Removal: A Genomic and Functional Characterization by Maria Eduarda Castro do Nascimento, Letícia Coelho Montagna, Laíza Manfroi, Yan de Oliveira Laaf, Luigi Ferrazza Maiochi, Marcus Adonai Castro da Silva, André Oliveira de Souza Lima

“…Conclusions: Genomic analysis suggests that P. megaterium LAMA1607 possesses the mechanistic functions for phosphorus uptake, transport, and storage while also identifying additional biotechnologically relevant enzymes and capabilities. …”
Get full text

Natural ligand 3,3’-diindolylmethane functions as an AHR agonist to modulate angiogenesis and organ development in chicken embryos by Gee-yea Lim, Hao Chen, Woo-seon Song, Dong-hee Koh, Dong-ha Kim, Hisato Iwata, Eun-Young Kim

“…Aryl hydrocarbon receptor (AHR) is a ligand-dependent transcription factor that is crucial for regulating various toxicological responses and physiological functions. Recent studies have highlighted that interactions between AHR and certain natural ligands can modulate inflammation and immune responses, offering therapeutic potential for a wide range of diseases. …”
Get full text

Relationship of handgrip strength, asymmetries, and calf circumference with functional capacity in individuals with intellectual disabilities: an age group analysis by Justine Mendoza-Puelma, Julio B. Melo, Gerson Ferrari, Paloma Ferrero-Hernández, Alexis Espinoza-Salinas, Pedro Valdivia-Moral, Antonio Castillo-Paredes, Emilio Jofré-Saldía, Claudio Farías-Valenzuela

“…This study aimed to determine the relationship between absolute and relative HGS, upper-limb strength asymmetries, and CC with functional capacity in individuals with ID. …”
Get full text

Effects of Cerebellar Transcranial Magnetic Stimulation on the Motor Function of Patients With Stroke: A Systematic Review and Meta‐Analysis by Yongxin Zhu, Juncong Yang, Kun Wang, Xianwen Li, Jiahui Ling, Xie Wu, Lianhui Fu, Qi Qi

“…Conclusion cTMS effectively improves motor function in patients with stroke, particularly during the subacute phase with excitatory stimulation and moderate intensities (≤ 80%RMT). …”
Get full text

Morphological, functional and biochemical differences in cardiac adaptation to endurance exercise among male and female amateur marathon runners by Zofia Lasocka-Koriat, Zofia Lasocka-Koriat, Zuzanna Lewicka-Potocka, Zuzanna Lewicka-Potocka, Anna Kaleta-Duss, Nikola Bulman, Ewelina Marciniak, Leszek Kalinowski, Leszek Kalinowski, Ewa Lewicka, Alicja Dąbrowska-Kugacka

“…However, activities of high intensity such as marathon running may adversely affect cardiac morphology and function, especially in the heterogenous group of amateur athletes. …”
Get full text

The correlation between neutrophil/lymphocyte ratio and the MRI burden and cognitive function in patients with cerebral small vessel disease by Mengyao Zhao, Mengyao Zhao, Xiaohua Xie, Xiaohua Xie, Zhiwei Hao, Zhiwei Hao, Mengsi Ren, Zhenjie Teng, Zhenjie Teng, Jing Xu, Jing Xu, Chunhui Shan, Yanhong Dong, Yanhong Dong, Peiyuan Lv, Peiyuan Lv

“…ObjectiveAims to explore the relationship between neutrophil/lymphocyte ratio (NLR) and the total burden of imaging markers and cognitive function in patients with cerebral small vessel disease (CSVD).MethodsA retrospective study was conducted on 148 hospitalized CSVD patients at Hebei General Hospital from January 2022 to September 2024, with complete clinical and laboratory data. …”
Get full text

Optimizing oral 3-hydroxybutyrate dosage using pharmacokinetic model to improve cognitive function and mood in healthy subjects by Kentaro Nishioka, Kentaro Nishioka, Kentaro Nishioka, Takahiro Ishimoto, Mariko Sato, Ruki Yasuda, Yumi Nakamura, Hiroshi Watanabe, Toshihide Suzuki, Yudai Araragi, Yukio Kato, Ken-ichi Yoshida, Norihito Murayama

“…Previous studies indicated that achieving a maximum concentration (Cmax) of 3-HB in plasma at 0.28 mM could initiate ketone metabolism in the brain; we hypothesized that attaining this Cmax would improve brain health.MethodsWe aimed to demonstrate the efficacy of an optimized single oral dose of 3-HB on cognitive function and mood through two clinical studies: a pharmacokinetic study and an efficacy study. …”
Get full text

Transcranial photobiomodulation improves functional brain networks and working memory in healthy older adults: An fNIRS study by Qin Yang, Xiujuan Qu, Can Sheng, Xing Zhao, Guanqun Chen, Xiaoni Wang, Yuxia Li, Wenying Du, Xiaoqi Wang, Yu Sun, Xiaobo Li, Haijing Niu, Ying Han

“…Objective: This randomized, single-blind, sham-controlled crossover study aimed to investigate the hypothesis that tPBM improved working memory in healthy older adults through the mechanism of optimizing the properties of the resting-state functional brain networks. …”
Get full text

Auricular acupoint therapy for functional gastrointestinal disorders: a systematic review and meta-analysis of randomized clinical trials by Meng-Yuan Shen, Ze-Jiong Li, Shu-Han Wang, Tian-Chen Lin, Qin-Yi Lou, Shan Liu, Dan-Dan Feng, Dong-Dong Yang, Chen-Juan Wang, Zhe-Kai Ying, Rong Zhou, Jian-Nong Wu

“…IntroductionThis study aims to conduct a systematic review and meta-analysis of randomized controlled trials to evaluate the efficacy and safety of auricular acupoint therapy (AAT) for functional gastrointestinal disorders (FGIDs).MethodsWe conducted a thorough search across eight databases, including PubMed, EMBASE, Web of Science, the Cochrane Library, CNKI, Wanfang, VIP, and CBM. …”
Get full text

New insights into the function and mechanisms of piRNA PMLCPIR in promoting PM2.5-induced lung cancer by Lin Xu, Wanli Ma, Xiaoyu Huo, Jiao Luo, Ruoxi Li, Xiaoxiao Zhu, Xiangbin Kong, Kunming Zhao, Yuan Jin, Meihua Zhang, Xianshu Li, Ling Wang, Wei Han, Dianke Yu

“…In vitro proliferation, migration, and invasion assays were performed to study the function of piRNA. RNA-sequencing was used to elucidate the the mechanisms of how piRNA mediates cell functions. …”
Get full text

Can Biomarkers Predict Kidney Function Recovery and Mortality in Patients with Critical COVID-19 and Acute Kidney Injury? by Noemí Del Toro-Cisneros, José C. Páez-Franco, Miguel A. Martínez-Rojas, Isaac González-Soria, Juan Antonio Ortega-Trejo, Hilda Sánchez-Vidal, Norma A. Bobadilla, Alfredo Ulloa-Aguirre, Olynka Vega-Vega

“…<b>Results</b>: A total of 60 patients were recruited, of whom 29 (48%) survived hospitalization and recovered kidney function by day 90. In the survivors, 79% presented complete recovery (CRR) and the remaining (21%) recovered partially (PRR). …”
Get full text

Comparison of the effects of remimazolam and dexmedetomidine on the quality of recovery in functional endoscopic sinus surgery: a randomized clinical trial by Yaqiong Li, Hui Zhou, Fanfan Gao, Qianqian Guan, Shengbin Wang, Yvqing Tan, Shenghong Hu

“…Abstract Background Postoperative pain usually occur in patients who have undergone functional endoscopic sinus surgery (FESS). Remimazolam and dexmedetomidine could enhance the quality of recovery (QoR) after surgery. …”
Get full text

Kidney function is associated with plasma ATN biomarkers among Hispanics/Latinos: SOL-INCA and HCHS/SOL results by Natasha Z. Anita, Wassim Tarraf, Sayaka Kuwayama, Freddie Márquez, Charles DeCarli, Bharat Thyagarajan, Nora Franceschini, James P. Lash, Tanya Johns, Kevin A. González, Martha Daviglus, Haibo Zhou, Ariana M. Stickel, Frank J. Penedo, Tatjana Rundek, Doug Galasko, Hector M. González

“…Here, we examine the association between kidney function and plasma ATN markers among a diverse sample of Hispanic/Latino individuals living in the U.S. …”
Get full text

Abstract 062: N20 Potential And Imaging Biomarkers Of Functional Recovery In Acute Ischemic Stroke Patients And EVT by Alicia Martinez Piñeiro, Giuseppe Lucente, María Hernandez‐Perez, Jordi Cortés, Andrea Arbex, Meritxell Gomis Cortina, Laura Dorado Bouix, Natalia Pérez de la Ossa, Alba Ramos‐Fransi, Miriam Almendrote, Carlos Castaño, Sebastián Remollo, Maria Rosa García Sort, Patricia Cuadras Collsamata, Mónica Millán, Antoni Dávalos

“…Introduction PROMISE trial has shown high predictive accuracy of the N20 somatosensory evoked potential (SEP) response on functional recovery in patients with AIS undergoing endovascular thrombectomy (EVT). …”
Get full text

Metagenomic Analysis Identifies Sex‐Related Gut Microbial Functions and Bacterial Taxa Associated With Skeletal Muscle Mass by Hang A. Park, Joohon Sung, Yoosoo Chang, Seungho Ryu, Kyung Jae Yoon, Hyung‐Lae Kim, Han‐Na Kim

“…ABSTRACT Background This study aimed to explore the association between gut microbiota functional profiles and skeletal muscle mass, focusing on sex‐specific differences in a population under 65 years of age. …”
Get full text

Left atrium phasic function decreases in adult patients with repaired tetralogy of fallot: a case–control study by Keiya Sato, Ken Takahashi, Yusuke Akatsuka, Hiroyuki Sato, Hirohisa Kago, Azusa Akiya, Satoshi Akimoto, Mayumi Ifuku, Yu Hosono, Sachie Shigemitsu, Kotoko Matsui, Keisuke Nakanishi, Shiori Kawasaki, Toshiaki Shimizu

“…Recently, LA strains assessed using a speckle tracking system have been used as novel sensitive indicators of LA function. Therefore, we aimed to evaluate LA function and investigate changes with age in patients with rTOF using speckle-tracking echocardiography. …”
Get full text

Pragmatic questionnaire-based evaluation of auditory function in individuals with major neurocognitive disorders and hearing loss in diverse contexts by Panagiotis Alexopoulos, Panagiotis Alexopoulos, Panagiotis Alexopoulos, Panagiotis Alexopoulos, Antonios Alexandros Demertzis, Panagiotis Biris, Polychronis Economou, Eric Frison, Piers Dawes, Iracema Leroi

Get full text