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Machine Learning for Predicting Postoperative Functional Disability and Mortality Among Older Patients With Cancer: Retrospective Cohort Study
Published 2025-05-01“…ObjectiveWe aimed to develop and validate machine-learning models to predict postoperative functional disability (≥5-point decrease in the Barthel Index) or in-hospital death in patients with cancer aged ≥ 65 years. …”
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4542
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4543
Changes in Brain Activity and Functional Connectivity During Spinal Nerve Stimulation in a Rat Model of Overactive Bladder
Published 2025-06-01“…Purpose Sacral neuromodulation is widely used for refractory overactive bladder; however, its mechanism of action remains unclear. This study aims to investigate real-time changes in brain activity and functional connectivity (FC) during neuromodulation in an overactive bladder (OAB) rat model using functional magnetic resonance imaging. …”
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4544
Relationship between central hemodynamic parameters and body composition and the functional state of neuro-autonomic regulation in young men
Published 2024-07-01“…The aim of the study is to examine the relationship between central hemodynamic parameters and body composition by considering baseline functional state of neuro-autonomic regulation according to the index of regulatory system activity (IRSA) in young men. …”
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4546
Development of an efficient expression system for human chaperone BiP in Pichia pastoris: production optimization and functional validation
Published 2025-03-01“…However, a growing amount of data also associates BiP with many distinct functions in subcellular locations outside the ER. …”
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4547
Effects of taxane-anthracycline and taxane only treatment on cardiac function in breast cancer—a retrospective cohort study
Published 2025-04-01“…Trajectories of ejection fraction and diastolic function associated markers over the follow-up periods were analysed by linear mixed models. …”
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4548
Identification of functional SNP associated with sperm quality in porcine ANXA5 that contributes to the growth of immature Sertoli cell
Published 2025-05-01“…AnnexinA5 (ANXA5) has been identified as a positional candidate gene for reproduction and fertility traits in boars, but its role in testicular tissue development, as well as genetic variations remain unclear. The aim of this study was to explore the effect of ANXA5 in the growth of swine Sertoli cells and identify its functional variations. …”
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4549
Insular Cortex Modulation by Repetitive Transcranial Magnetic Stimulation with Concurrent Functional Magnetic Resonance Imaging: Preliminary Findings
Published 2025-06-01“…Moreover, empirical evidence of target engagement of this region remains scarce. This study aimed to stimulate the insula with rTMS and assess blood oxygen level-dependent (BOLD) signal modulation using concurrent functional magnetic resonance imaging (fMRI). …”
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Bacillus vallismortis acts against ginseng root rot by modifying the composition and microecological functions of ginseng root endophytes
Published 2025-04-01“…IntroductionThe endophytic microbiome serves a crucial function as a secondary line of defense against pathogen invasion in plants. …”
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4551
The Effect of Tacrine on Functional Response of the Lower Oesophageal Sphincter Assessed by Endoscopic Luminal Impedance Planimetry in Experimental Pigs
Published 2024-11-01“…<b>Conclusions:</b> Endoscopic luminal impedance planimetry is a feasible method to evaluate functional response of the lower oesophageal sphincter to tacrine in experimental pigs. …”
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4552
Exploring the metabolic dynamics, storage stability, and functional potential of Lacticaseibacillus rhamnosus Probio-M9-fermented milk
Published 2025-02-01“…However, research on its efficacy as a starter culture for milk fermentation and the associated metabolic shifts remains limited. This study aimed to track the dynamic metabolomic changes of Probio-M9 during the fermentation process. …”
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4553
Variants in Neurotransmitter-Related Genes Are Associated with Alzheimer’s Disease Risk and Cognitive Functioning but Not Short-Term Treatment Response
Published 2025-04-01“…<i>BCHE</i> rs1803274 was associated with worse cognitive functioning. None of the genetic and non-genetic factors studied were associated with the response to pharmacological treatment. …”
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4554
Impaired lung function and associated risk factors in children born prematurely: a systematic review and meta-analysis
Published 2024-10-01“…This systematic review and meta-analysis aims to quantify lung function in preterm-born children and identify risk factors for a compromised lung function. …”
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4555
Assessment of the Abnormalities in Chest Computed Tomography and Pulmonary Function Test in Convalescents Six Months After COVID-19
Published 2025-04-01“…<i>Background:</i> Despite the multiple waves of the COVID-19 pandemic, follow-up strategies for recovered patients remain inconclusive. This study aimed to evaluate chest computed tomography (CT) and pulmonary function test (PFT) abnormalities in convalescents six months after COVID-19 and to compare these findings with those from a representative population cohort. …”
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4556
Personal exposure to PM2.5 and its chemical components in individuals with COPD: associations with lifestyle and lung function
Published 2025-07-01“…However, research examining how PM2.5 exposure and lifestyle influence disease severity remains limited. This study aimed to assess personal PM2.5 exposure levels and analyze its chemical composition among COPD patients in Atlanta, Georgia, along with investigating the association between exposure levels, lifestyles, and lung functions. …”
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Sex-Dependent Rhizosphere Microbial Dynamics and Function in <i>Idesia polycarpa</i> through Floral and Fruit Development
Published 2024-10-01“…Here, we investigate the differences in root bacterial community structures between male and female plants at different developmental stages, identifying bacterial strains associated with plant sex through functional predictions. This study aims to inform the optimal allocation of male and female plants during cultivation and provide a theoretical basis for sex identification and breeding. …”
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4559
Associations Between Postoperative Symptom Clusters and Functional Status in Lung Cancer Patients: A Cross-Sectional Study
Published 2025-06-01“…Yali Liu,1,&ast; Siya Lin,2,&ast; Meirong Bai,1 Huochun Yi3 1Department of Thoracic Surgery, Zhongshan Hospital Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, 361004, People’s Republic of China; 2School of Nursing, Fujian Medical University, Fuzhou, Fujian, 350122, People’s Republic of China; 3Center of Clinical Laboratory, Zhongshan Hospital Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, 361004, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Meirong Bai, Department of Thoracic Surgery, Zhongshan Hospital Xiamen University, School of Medicine, Xiamen University, 201 hubin South Road, Siming District, Xiamen, Fujian, 361004, People’s Republic of China, Email 157576198@qq.com Huochun Yi, Center of Clinical Laboratory, Zhongshan Hospital Xiamen University, School of Medicine, Xiamen University, 201 hubin South Road, Siming District, Xiamen, Fujian, 361004, People’s Republic of China, Email yhc1818@163.comBackground: Symptom clusters in cancer symptom management research, providing a scientific basis for developing effective strategies for symptom assessment and intervention aimed at improving patient quality of life and survival.Objective: To analyze symptom clusters in postoperative lung cancer patients, examine its influenced factor, and explore the relationship between postoperative symptom clusters and functional status in lung cancer patients.Methods: Between August 2023 and February 2024, 441 lung cancer patients who underwent surgical treatment in the Department of Thoracic Surgery at a tertiary hospital in Xiamen were selected. …”
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Comprehensive physical rehabilitation of patients with heart failure: impact on clinical and functional status and analysis of problems related to the enrollment
Published 2022-03-01“…Aim. To evaluate functional, clinical and psychological status of patients with class II-III heart failure, who underwent comprehensive cardiac rehabilitation program.Material and methods. …”
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