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4481
Comparison between Inhibition of CatSper and KSper Channels with NNC 55-0396 and Quinidine on Human Sperm Function
Published 2025-03-01“…These two channels regulate intracellular calcium concentration ([Ca2+]i) and membrane potential. Our study aims to investigate and compare the contributions of these channels in capacitated sperm function. …”
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4482
Prevalence and functional impact of flexible flatfoot in school-aged children: a cross-sectional clinical and postural assessment
Published 2025-08-01“…Objectives This study aimed to (1) determine the prevalence of flexible flatfoot among children aged 6–12 years using standardized clinical criteria and the Foot Posture Index-6 (FPI-6); and (2) evaluate its functional implications by analyzing associations with pain intensity, physical activity levels, and body mass index (BMI). …”
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4483
Pedotransfer functions for soil organic carbon stock and soil porosity interpretation in diverse palm oil plantation soils
Published 2025-06-01“…The accurate estimation of soil organic carbon stocks (SOCs) is crucial in sustainable oil palm plantation management. Pedotransfer functions (PTFs) serve as an essential predictive tool for enhancing the interpretation and estimation of soil organic carbon stocks (SOCs) and soil porosity. …”
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4484
Higher triglyceride-glucose index is associated with severe proteinuria and decreased renal function in patients with primary membranous nephropathy
Published 2025-03-01“…Abstract Background In recent years, the triglyceride-glucose (TyG) index has emerged as a reliable surrogate marker of insulin resistance (IR). This study aimed to investigate the association between the TyG index and severe proteinuria or decreased renal function in patients with primary membranous nephropathy (PMN). …”
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4485
Impact of gastrointestinal and psychological symptoms on disease activity and functional impairment in patients with spondyloarthritis: a cross-sectional study
Published 2025-03-01“…High disease activity and functional impairment were common. 65.3% reported ≥ 2 GI symptoms, predominantly abdominal pain and diarrhea. …”
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4486
The Role of Chemokine (C‐C Motif) Ligand 7 (CCL7) in Hepatocellular Carcinoma: Expression, Function, and Mechanisms
Published 2025-03-01“…ABSTRACT Aim AHepatocellular carcinoma (HCC) is a malignant neoplasm characterized by a poor prognosis, with its incidence rising globally. …”
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4487
Effects of sulforaphane on cognitive function in patients with frontal brain damage: study protocol for a randomised controlled trial
Published 2020-10-01“…Preclinical research has shown that sulforaphane can significantly improve spatial localisation and working memory impairment after brain injury. The primary aim of this double-blind randomised controlled clinical trial is to assess the efficacy of sulforaphane for improving cognitive function in patients with frontal brain damage.Methods and analysis Ninety eligible patients will be randomly allocated to an active treatment or a placebo group in a 2:1 ratio. …”
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4488
The Role of Endothelin‐1, Kidney Function and Diabetes in Patients With Coronary Artery Disease Underwent Percutaneous Coronary Intervention
Published 2025-07-01“…ABSTRACT Objective This study aimed to explore the association between plasma big endothelin‐1 (ET‐1) and major adverse cardiovascular events (MACE) in CAD patients who underwent PCI with a focus on the influence of kidney function and diabetes status in secondary prevention. …”
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4489
The Effects of Carotid Pathologies on Short-Term Functional Outcomes After First-Ever Small Vessel Occlusion Stroke
Published 2025-07-01“…<b>Background:</b> While carotid pathologies are well-established risk factors for stroke, their specific effects on outcomes following stroke that cannot be classified as atherosclerotic remain unclear. In this study, we aimed to determine whether carotid pathologies are associated with functional dependence (FD) 3 months after small vessel occlusion (SVO) stroke. …”
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4490
INFLUENCE OF THE COMBINATION DRUG PRESTANS (PERINDOPRIL A, AMLODIPINE) ON MORPHO-FUNCTIONAL PARAMETERS OF ARTERIAL BED IN ESSENTIAL HYPERTENSION
Published 2017-12-01“…Aim. Recently, the problem of endothelial dysfunction is in high interest. …”
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4491
Early Sport Specialization in a Pediatric Population: A Rapid Review of Injury, Function, Performance, and Psychological Outcomes
Published 2025-04-01“…Although numerous studies have explored early sport specialization, there has been no summative review on the topic in regard to the comprehensive impact on outcomes in these athletes. This study aims to systematically review the literature to determine the impacts of early specialization on injury, function, performance, sport success, and psychological outcomes. …”
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4492
Longitudinal Trajectories of Cognitive Function Among Chinese Middle-Aged and Older Adults: The Role of Sarcopenia and Depressive Symptoms
Published 2025-04-01“…Sarcopenia and depressive symptoms were associated with the “Low and Decline” trajectory of cognitive function [Overall: OR (95%CI) of 0.315 (0.259, 0.382) and 0.417 (0.380, 0.459)]. …”
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4493
Fatty infiltration predicts retear and functional impairment following rotator cuff repair: systematic review and meta-analysis
Published 2025-03-01“…But there remains controversy on the prognostic effects of FI in RC tears, especially for patients with moderate and severe FI. This study aims to systematically review the relationship between the severity of preoperative FI and risk of retear, and the association between preoperative FI and functional outcomes. …”
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4494
Pain, Physical Function, Radiographic Features, and Quality of Life in Knee Osteoarthritis Agricultural Workers Living in Rural Population
Published 2019-01-01“…Background. The aim of this study was to analyse the relationship between the clinical manifestations, disease severity based on radiography images, functional activity level, and quality of life in patients with knee osteoarthritis in a rural population living in Serbian enclaves in Kosovo, as well as to determine the correlation between the WOMAC and the EQ-5D questionnaire in this population. …”
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4495
Cognitive functioning in young adults after mild COVID-19: A case-control study from Iran
Published 2025-12-01“…Despite extensive research on the acute effects of COVID-19, the long-term psychological and neurological sequela remain inadequately explored. This study aimed to investigate cognitive function after COVID-19 infection compared to a control group of non-infected subjects. …”
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4496
A simple pedotransfer function to estimate fine fraction organic carbon contents of surface horizons in French soils
Published 2025-07-01“…., fine fraction organic carbon (OCfine) and coarse fraction organic carbon, to improve our ability to understand controlling factors and predict SOC contents and SOC stability. In this study, we aimed at building a simple pedotransfer function to estimate OCfine content measured using a size fractionation protocol in French soils. …”
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4497
Altered spontaneous brain activities in maintenance hemodialysis patients with cognitive impairment and the construction of cognitive function prediction models
Published 2023-12-01“…Objective The brain neuromechanism in maintenance hemodialysis patients (MHD) with cognitive impairment (CI) remains unclear. The study aimed to probe the relationship between spontaneous brain activity and CI by using resting-state functional magnetic resonance imaging (rs-fMRI) data.Methods Here, 55 MHD patients with CI and 28 healthy controls were recruited. …”
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4498
Characterising the metabolic functionality of the preterm neonatal gut microbiome prior to the onset of necrotising enterocolitis: a pilot study
Published 2024-12-01“…The aim of this pilot study was to characterise the metabolic functionality of the preterm gut microbiome prior to the onset of NEC compared with healthy controls. …”
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4499
Serum calprotectin and renal function decline in ANCA-associated vasculitides: a post hoc analysis of MAINRITSAN trial
Published 2023-10-01“…Objective Serum calprotectin appears to be an interesting biomarker associated with renal vascular disease activity in antineutrophil cytoplasm antibody (ANCA)-associated vasculitis (AAV). The aim of this study was to assess whether serum calprotectin levels can predict decline in renal function in AAV patients receiving maintenance therapy.Methods Serum calprotectin levels were assessed at inclusion and month 6 in AAV patients, in complete remission after induction therapy, randomly assigned to rituximab or azathioprine. …”
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4500
Differences in ankle stabilizing function between the upper and lower fiber bundles of the anterior talofibular ligament: an anatomical study
Published 2025-07-01“…Abstract This study aimed to clarify the differences in the stabilizing functions of the upper and lower fiber bundles of the anterior talofibular ligament (ATFL). …”
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