What factors are associated with informal carers’ psychological morbidity during end-of-life home care? A systematic review and thematic synthesis of observational quantitative stu... by Tracey Shield, Kerin Bayliss, Alexander Hodkinson, Maria Panagioti, Alison Wearden, Jackie Flynn, Christine Rowland, Penny Bee, Morag Farquhar, Danielle Harris, Gunn Grande

“…Patients’ other symptoms and functional impairment may relate to carer mental health, but findings were unclear. …”
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Analysis of the Causes of Urban Sprawl in Iran by keramatollah Ziari, Saeed Zanganeh Shahraki, Negin Rajabzadeh, Mohsen Abbas Nejad Jelogir

“…Based on the research findings, any planning aimed at controlling and managing urban sprawl must be framed within the context of government action. …”
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Uncovering the role of Gpr45 in obesity regulation by Eva O. Karolczak, Chia Li, Ivan C. Alcantara, Isabel M. Cohen, Claire Gao, Cuiying Xiao, Abigail I. Goldschmidt, Cynthia A. Pinkus, Junjie Li, Monica M. Li, Ryan M. Esquejo, Jean-Philippe Fortin, Kendra K. Bence, Marc L. Reitman, Michael J. Krashes

“…Methods: Three novel transgenic mouse models were engineered to investigate the functional contribution of Gpr45 to body weight and appetite regulation: 1) a global Gpr45 knockout, 2) a conditional floxed Gpr45 allele, and 3) a Gpr45-CreERT2 knock-in. …”
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Hsa_circ_0002238 promotes the malignant behavior of colorectal cancer by Lin-Ting Zhang, Yuejia Zhou, Tiantian Wang, Boran Chen, Zhigao Cai, Shubin Wang, Gangling Tong

“…Circular RNAs (circRNAs) have emerged as crucial players in the onset and progression of CRC. This research aims to investigate the expression levels of a novel circRNA, hsa_circ_0002238, in CRC and to explore its association with alterations in CRC functional phenotypes.MethodsHigh-throughput RNA sequencing identified abnormal circRNA expressions, and qRT-PCR validated hsa_circ_0002238 expression. …”
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Demand and Influencing factors for community health services during chemotherapy of patients with advanced cancer by Qianqian Li, Xunrui Chen, Wenying Zhang, Haihua Yuan, Yanjie Zhang, Bin Jiang, Feng Liu

“…Attention toward patients with advanced cancer undergoing chemotherapy is gradually increasing. This study aims to understand the primary care demands of such patients and the factors influencing these demands. …”
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Serum extracellular vesicle microRNAs as potential biomarkers to predict pembrolizumab response and prognosis in metastatic non-small cell lung cancer patients by Daniela Lamorte, Luciana De Luca, Alfredo Tartarone, Stefania Trino, Irene Giulivo, Angelo De Stradis, Maddalena Maietti, Antonella Caivano, Ilaria Laurenzana

“…In the context of Non-Small Cell Lung Cancer (NSCLC) immunotherapy there’s a great need for novel predictive and prognostic biomarkers. This study aims to analyze cEVs microRNAs in serum of advanced stage NSCLC patients with PD-L1 expression ≥50% at diagnosis, before first-line pembrolizumab, to evaluate their possible role as potential biomarkers for immunotherapy response prediction and outcomes.MethodscEVs were isolated from serum of healthy subjects and NSCLC patients at diagnosis. …”
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Standardization of epistemic trust/mistrust/credulity questionnaire: Examining validity and reliability among adolescents Standardization of ETMCQ among adolescents by Raziyeh Hashemi, Mehdi Reza Sarafraz, Habib Hadian Fard, Mohammad Reza Taghavi

“…Epistemic trust means validating and fitting information that comes from others and has relationships with pathological and therapeutic factors. Therefore, the aim of this study was to investigate the psychometric properties of the Persian version of the Trust/Distrust/Epistemic Validity Questionnaire (ETMCQ) in the general population. …”
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Delivery of miR-26a-5p by Subcutaneous Adipose Tissue-Derived Extracellular Vesicles Alleviates Acute Lung Injury in Mice Through CHUK/NF-κB Pathway by Xie Y, Ran L, Yue C, Wang C, Chen F, Su Y, Qin Y, Zhang Q, Liu J, Du N, Zhang L, Jiang Y, Liu G

“…Among these, adipose tissue-derived extracellular vesicles (EVs) have emerged as novel mediators of intercellular communication, capable of delivering bioactive molecules such as microRNAs to target cells. This study aimed to elucidate the immunomodulatory roles and underlying mechanisms of adipose tissue-derived EVs in the pathogenesis of ARDS.Methods: Subcutaneous adipose tissue extracellular vesicles (SAT-EVs) were collected from the mice via ultracentrifugation. …”
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Magnetically sensitive nanocomposites for targeted antitumor therapy with application of gemcitabine by N. M. Korniichuk, S. P. Turanska, A. L. Petranovska, M. V. Abramov, P. P. Gorbyk, N. Yu. Luk'yanova, N. V. Kusyak, V. F. Chekhun

“…The consequences of oxidative stress are induction of apoptosis, enhancement of lipid peroxidation processes, as well as structural and functional rearrangement of biological membranes. The prospects have been shown of further studies of Fe3O4@GEM/Ol.Na/PEG/HER2+PS MF in order to create on their basis a magnetically carried remedy for use in targeted antitumor therapy. …”
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Promoting the Integration of Public Perspective into Urban Design Decision-Making Based on Crowdsourced Visual Perception Method by Lu HUANG, Takuya (JPN) OKI

“…Thus, understanding and integrating public urban perception not only enhances design responsiveness to user needs but also fosters a harmonious balance of functional efficiency and humanistic care. Crowdsourced visual perception data and analysis methods, with their advantages of efficiency, broad representativeness, and low cost, have become key methodological tools in urban built environment research. …”
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CLINICAL ASPECTS OF PATIENTS WITH NON-REMOVABLE PROSTHESIS RESULTS OF ZRO2 COATED PROSTHESES by O.M. Yakovyn, Z.R. Ozhohan

“…Patients of 2nd and 3rd groups satisfied patients in terms of aesthetic and functional requirements. Shade, smoothness, integrity structures were remained unchanged. …”
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HMGB1 Inhibition Alleviates Chronic Nonbacterial Prostatitis by Suppressing M1 Polarization of Macrophages by Zhou J, Ding L, Chen J, Chen C, Jiang P, Mei Z, Jiang Q, Hua X

“…Co-immunofluorescence was used to analyze the functional phenotype of macrophages and spatial localization of HMGB1 in prostate of EAP mice. …”
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Development and Comparison of Interrupt-Based and Analog-to-Digital Converter Algorithms for Seed Counting in Precision Planters by A. Ghaffarnezhad, H. Navid, H. Karimi

“…IntroductionImproving field operations through precise spot planting rates depends on the accurate functioning of seed flow sensors within the working rows. …”
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Good Governance and Seigniorage in a Selected OPEC Countries and Iran by ALI Rashid Shamkhal, Kambiz Paykarjou, beitollah Akbari Moghaddam

“…Aim and Introduction Seigniorage, in addition to being a crucial economic tool, holds a significant position in terms of governance for governments. …”
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Exploring the nexus between hydroclimatic variability, population growth, land use land cover change, and long-term upper Nyong Basin River chemistry (Central Africa rainforest) by David Eric Komba, Gustave Raoul Nkoue Ndondo, Jean Riotte, Stéphane Audry, Bertil Nlend, Bernadette Nka Nnomo, Suzanne Ngo Boum-Nkot, Henriette Ateba Bessa, Enoh Jeanot Fongoh, Laurie Boithias, Christelle Lagane, Jules Rémy Ndam Ngoupayou, Marie Joseph Ntamak-Nida, Jacques Etame, Jean Jacques Braun

“…Abstract Hydrological and hydrogeochemical functioning of rivers depends on the relationship between climatic variability, land use and land cover change (LULCC), and population dynamics. …”
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Quantitative imaging datasets of surface micro- to mesoplankton communities and microplastic across the Pacific and North Atlantic oceans from the Tara Pacific expedition by Z. Mériguet, G. Bourdin, N. Kristan, L. Jalabert, O. Bun, M. Picheral, L. Caray-Counil, J. Maury, M.-L. Pedrotti, A. Elineau, D. A. Paz-Garcia, L. Karp-Boss, G. Gorsky, F. Lombard

“…In addition to describing and presenting the datasets, the complementary aim of this paper is to investigate and quantify the potential sampling biases associated with these two high-speed sampling systems and the different net types, in order to improve further ecological interpretations. …”
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Headache: A potential sequela of posterior reversible encephalopathy syndrome by M. Rodrigo-Gisbert, E. Caronna, A. Alpuente, M. Torres-Ferrús, P. Pozo-Rosich

“…However, there is a paucity of data that point to headache as a sequela of PRES. We aimed to explore its prevalence, characteristics, and impact. …”
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Phasic and periodic change of drought under greenhouse effect by Yang Li, Zhicheng Zheng, Yaochen Qin, Haifeng Tian, Zhixiang Xie, Peijun Rong

“…However, the phases and periodicity of drought changes in the ESAC remain largely unknown. Thus, this paper aims to identify the periodic characteristics of meteorological drought changes. …”
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Supply-Demand Matching Evaluation and Coupling Coordination of Cultural Ecosystem Services in Urban Park Green Spaces by Yang YU, Xian YANG, Xiang LI, Liyuan QIAN, Sixiang ZHOU

“…The spatial differentiation of supply-demand coordination relationships is evident within the main urban area.ConclusionBy overlaying the results of supply-demand matching types with coupling coordination levels, the research categorizes the service ranges of all park green spaces into three functional zones: efficient zones, transitional zones, potential zones, and proposes optimization strategies accordingly. …”
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The Effect of Iron Deficiency Stress on the Relative Expression of ZIP3, ZIP6, and ZIP7 Genes in Bread Wheat (Triticum aestivum L.) Cultivars by Saeed Rezaei Musa Dargh, Babak Abdollahi Mandoulakani, Raheleh Ghasemzadeh

“…Therefore, this research aimed to evaluate the expression of ZIP3, ZIP6, and ZIP7 genes in the leaves and roots of two Fe-efficient and -inefficient bread wheat cultivars at different growth stages under iron deficiency stress. …”
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