Regulatory role of lnc-MAP3K13-3:1 on miR-6894-3p and SHROOM2 in modulating cellular dynamics in hepatocellular carcinoma by Kuai Chen, Manqin Zhu, Qinghua Hu, Hui Huang, Ka Chen, Xia Shuai, Jinshi Huang, Qiang Tao, Zhibin Guo

“…The miR-6894-3p mimic regulated the activity of lnc-MAP3K13-3:1. Functional assays showed that lnc-MAP3K13-3:1 overexpression inhibited proliferation in HuH-7 and Li-7 cells, promoted apoptosis, reduced migration in Li-7 cells, but enhanced migration in HuH-7 cells. …”
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Safety of Extended Sedation with Sevoflurane in Patients with Severe Traumatic Brain Injury by D. R. Safiullin, A. K. Shabanov, A. A. Grin, R. A. Cherpakov, A. K. Evseev, A. I. Evdokimov, S. S. Petrikov, O. A. Grebenchikov

“…In conditions of increased sensitivity of damaged brain tissue to disruption of homeostasis, it is important to achieve stabilization of the vital functions of the body as soon as possible. Given the excess afferent impulse, adequate sedation and analgesia are an integral component of intensive care for patients with traumatic brain injury. …”
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„Looduse universaal-biblioteek“: raamatusarja juhtumiuuring / Universal Library by Loodus (1927–1931): a case study of the book series by Piret Pärgma

“…In the article I give a short overview of the publishing house Loodus and its contribution to literary translations in Estonia, introduce the goals and expectations for the series, the marketing strategy, analyse what was published, and touch on the subject of translators and translations. Functioning as a popular series for a diverse readership, the aim of the series was to introduce Estonian readers to the latest foreign literature and create a habit of buying books; the latter was encouraged by low price. …”
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MYOCARDITIS AS A LEGITIMATE PHENOMENON IN NON-COMPACTION MYOCARDIUM: DIAGNOSTICS, MANAGEMENT AND INFLUENCE ON OUTCOMES by O. V. Blagova, E. V. Pavlenko, N. V. Varionchik, A. V. Nedostup, V. P. Sedov, Е. A. Kogan, V. А. Zaydenov, А. G. Kupriyanova, A. Е. Donnikov, V. V. Kadochnikova, N. V. Gagarina, E. A. Mershina, V. Е. Sinitsyn, М. Е. Polyak, E. V. Zaklyazminskaya

“…Aim. To evaluate the prevalence of myocarditis in adult patients with non-compaction myocardium (NCM) of the left ventricle (LV), and its influence on the disease course, results of treatment and outcomes.Material and methods. …”
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Integrated proteomics and transcriptomics analysis reveals key regulatory genes between ER-positive/PR-positive and ER-positive/PR-negative breast cancer by Zhengjia Lu, Jiao Yang, Yang Feng, Jia Ming

“…Additionally, there were differences in functional pathway enrichment analysis (galactose_metabolism, glycolysis_gluconeogenesis, jak_stat_signaling_pathway, pentose_phosphate_pathway, et al.) and immune cell infiltration (CD8 T cell, Macrophages M1, et al.) between the high-risk and low-risk groups. …”
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Divergence in physical, chemical, and biological soil properties caused by different long-term bare fallow management and natural succession by Steffen Schlüter, Mengqi Wu, Maxime Phalempin, Lena Philipp, Evgenia Blagodatskaya, Thomas Reitz, Carsten Simon, Oliver Lechtenfeld, Hans-Jörg Vogel, Martin Schädler, Ines Merbach

“…The absence of plants has profound effects on many ecosystem functions of soil. Long-term bare fallow trials are valuable tools for studying the dynamics in soil carbon decline and associated soil degradation. …”
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Memory Mining and Spatial Transformation of Daily Landscape in Renewal of Tianjin Old City by Chunyan ZHANG, Xinyi ZHANG, Tianying HOU

“…Consequently, redeveloped old urban areas often lose their unique cultural identity, exhibit issues of homogenization, functional inadequacy, and spatial fragmentation. To address these challenges, this research aims to explore various carriers of urban daily landscape memory across different historical periods, systematically excavate the embedded memories, and establish meaningful connections between these memories and the spatial characteristics of daily landscapes, so as to strengthen residents sense of cultural identity, facilitate the co-development of urban vitality through the empathetic power of daily landscapes.Methods1) Selection basis for landscape memory entities: The research is grounded in the integrated perception of landscape and human interaction articulated in the European Landscape Convention. …”
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Dendritic cells pulsed with multifunctional Wilms’ tumor 1 (WT1) peptides combined with multiagent chemotherapy modulate the tumor microenvironment and enable conversion surgery in... by Machi Suka, Hiroyuki Yanagisawa, Nobuhiro Sato, Shigetaka Shimodaira, Masayuki Saruta, Shigeo Koido, Junichi Taguchi, Masamori Shimabuku, Shin Kan, Tuuse Bito, Takeyuki Misawa, Zensho Ito, Kan Uchiyama, Shintaro Tsukinaga, Toshifumi Ohkusa, Haruo Sugiyama

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Integrated Network Analysis to Identify Key Modules and Potential Hub Genes Involved in Bovine Respiratory Disease: A Systems Biology Approach by Aliakbar Hasankhani, Abolfazl Bahrami, Abolfazl Bahrami, Negin Sheybani, Farhang Fatehi, Roxana Abadeh, Hamid Ghaem Maghami Farahani, Mohammad Reza Bahreini Behzadi, Ghazaleh Javanmard, Sadegh Isapour, Hosein Khadem, Herman W. Barkema

“…After identifying respective modules by the two mentioned methods of WGCNA, functional enrichment analysis was performed to extract the modules that are biologically related to BRD. …”
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Study of the Effectiveness of Drugs Based on Molecular Complexes of Adenosine-polymer on the Model of Thermal Burn by E. D. Semivelichenko, A. A. Ermolaeva, V. V. Ponomarenko, A. V. Novoselov, G. A. Plisko, D. Yu. Ivkin, V. G. Antonov, V. E. Karev, I. A. Titovich, A. V. Eremin

“…Potentiometric titration of the functional groups of the VP copolymer was performed using a PP-20 pH meter (Sartorius AG, Germany). …”
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SOURCES OF FINANCING INDUSTRIAL COMPLEX ENTERPRISES by Anzhela Zakhitovna Namitulina, Mikhail Nikolaevich Prokofiev, Nikolay Viktorovich Vorovsky

“…Under these circumstances, current CMO exit from the crisis is a problem of formation of an investment to ensure its development system. Objectives. The aim of the article is to study sources of financing and investment enterprises of the military-industrial complex, study and analysis of the financing of investment sphere of defense industry enterprises; Development of the best ways of functioning of the integrated companies with a view to achieving high economic efficiency in the military and economic cooperation on the basis of military technology, defense industry places on its analysis of the global market. …”
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Environmentally friendly synthesis of nanoporous silica materials using quercetin as a morphogenetic agent by A.R. Zare Hoseinabadi, E. Rafiei Taqanaki, S. Hafez Ghoran, A.M. Amani, H. Kamyab, A. Razmfarsa, E. Khalili, M. Yusuf, S. Rajendran

“…Furthermore, the Barrett-Joyner-Halenda analysis provided measurements of the pore size at 24.312 nm and the pore volume at 0.336 square centimeters per gram, respectively.CONCLUSION: The study results outcomes demonstrated that quercetin forms a macromolecular scaffold that functions as a template for the formation of mesoporous silica nanoparticles. …”
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Clinical and laboratory significance of soluble claudin-5 and VEGF in ovarian cancer by N. E. Kushlinskii, S. E. Kulikova, F. A. Gugnin, S. Yu. Nezhdanova, A. N. Gratchev, D. O. Utkin, D. A. Tsekatunov, I. B. Ryzhavskaya, D. N. Kushlinskiy, E. S. Gershtein, I. S. Stilidi

“…In addition to their physiological functions, claudin 5 and VEGF play an important role in pathogenesis of various diseases including malignant neoplasms.Aim. …”
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Comparative analysis of the integration of autologous and allogeneic cryopreserved tendons in the femoral canal on a model of laboratory animals by A. A. Budaev, N. S. Tropskaya, N. V. Borovkova, A. M. Fayn, G. P. Titova, M. S. Makarov, A. Yu. Vaza, I. V. Ponomarev, E. A. Kislyakova, O. S. Kislitsyna, A. A. Offitserov, D. A. Kisel', M. V. Storozheva, V. V. Slastinin, A. A. Kanibolotskiy

“…Cryopreserved allogeneic tendons were able to integrate into the body's own tissues without pronounced structural and functional disorders. According to the treadmill test, the distance covered by the animals of both experimental groups did not differ statistically significantly from the values in the control group (without tendon transplantation) after 3 and 6 weeks…”
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The impact of renal tubulointerstitial dysfunction on the early and long-term prognosis in chronic heart failure patients with preserved left ventricular ejection fraction by V. V. Syvolap, V. A. Lysenko

“…Aim. To study the dependence of the early-term (1 year) and long-term (5 years) prognosis in patients with chronic heart failure (CHF) of ischemic origin with preserved left ventricular ejection fraction (LVEF) depending on renal tubulointerstitial functional disorders. …”
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Thymic Microenvironment Remodeling in Cancer Cachexia as a Determinant of Checkpoint Inhibitor Efficacy and Toxicity by Run‐Kai Huang, Yan‐Fang Xing, Xiang‐Yuan Wu, Zhao‐Hui Shi, Li Wei, Xiao‐Tong Lv, Lin‐Jiao Peng, Xiu‐Qing Pang, Qin‐Tai Yang, Xing Li

“…The impact of cancer cachexia on thymic involution and its clinical significance remains unclear. This study aimed to investigate this effect and its association with immune checkpoint inhibitor (ICI) treatment. …”
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Early Childhood Nutrition and Development in Atopic Families from Northeastern Bulgaria by Albena Toneva, Antoniya Hachmeriyan, Rouzha Pancheva, Miglena Marinova-Achkar

“…Early allergic conditions and maternal behaviors are linked to cognitive and neurodevelopmental challenges. Our study aims to compare children from atopic families focusing on early nutrition and the neuropsychological development of children, especially in the presence of an allergic predisposition. …”
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SPECIFICS OF SUBFRACTIONAL SPECTRUM OF APOLIPOPROTEIN B RELATED LIPOPROTEINES IN CAROTID OR CORONARY ATHEROSCLEROSIS PATIENTS by N. E. Gavrilova, V. A. Metelskaya, I. N. Ozerova, E. B. Yarovaya, S. A. Boytsov

“…Apolipoprotein (apo)B-containing lipoproteines of low density are heterogeneous by their nature, and differ by their lipid and protein contents, charge, particle size and functional activity. High blood level of small dense particles of low-density lipoproteines (LDL) is related to higher risk of coronary heart disease 3-5 times irrelevant to cholesterol level they contain.Aim. …”
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A new method of assessing microcirculation of the central retina in patients with different stages of diabetic macular edema in type 2 diabetes by S.A. Suk, S.Yu. Mogilevskyy, M.I. Kovtun, B.B. Zhupan

“…Optical coherence tomography angiography is a non-invasive technique that allows for visualization of retinal vascular plexus layers, quantification of microvascular parameters and correlation with functional and morphological data. Research aimed at identifying early preclinical biomarkers of micro­vascular abnormalities in the diabetic retina is very important, as early treatment is associated with better outcomes. …”
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Clinical outcomes and genomic profiles of MAP2K1-mutated primary cutaneous melanocytic tumoursResearch in context by Chiel F. Ebbelaar, Anne M.L. Jansen, Leonie C.M. Speet, Frans Schutgens, Sietske Zoetemeyer, Anne-Marie Cleton-Jansen, Marijke R. van Dijk, Gerben E. Breimer, Lourens T. Bloem, Wendy W.J. de Leng, Remco van Doorn, Karijn P.M. Suijkerbuijk, Anne M.R. Schrader, Willeke A.M. Blokx

“…These mutations were categorised into three functional classes: Class I (RAF-dependent), Class II (RAF-regulated), and Class III (RAF-independent). …”
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