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43781
Transcranial Direct Current Stimulation (tDCS) for Borderline Personality Disorder (BPD): Why and How?
Published 2025-05-01“…Pilot randomized controlled trials report moderate effect sizes for improvements in emotional regulation, inhibitory control, and rejection sensitivity, along with ancillary gains in executive functioning and reductions in depressive and substance-use symptoms when stimulating the left dorsolateral prefrontal cortex. …”
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43782
Incidence, causes and prognostic outcomes of acute coma: a nationwide population-based retrospective cohort study in Taiwan
Published 2025-05-01“…Secondary outcomes assessed were reversible coma, hospitalisation rates, 30-day mortality, 1-year medical utilisation and long-term functional outcomes. Cox regression models identified factors influencing long-term mortality.Results The overall event rate for acute coma was 4.23 per 1000 ED visits, and the incidence rate was 0.93 per 1000 person-years. …”
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43783
Cytokine Gene Variants as Predisposing Factors for the Development and Progression of Coronary Artery Disease: A Systematic Review
Published 2024-12-01“…Single nucleotide polymorphisms (SNPs), capable of generating functional modifications in IL genes, appear to be associated with CAD risk. …”
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43784
Mechanism of immune escape mediated by T cell depletion induced by TOX signaling pathway in cervical cancer microenvironment
Published 2025-07-01“…Therefore, this study aimed to explore the immune escape mechanism mediated by the depletion of CD8+ T cells induced by the SNX9/TOX signaling pathway in the CC microenvironment. …”
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43785
Pharmacological potential of 3,5-dimethyl-4-(3-(5-nitrofuran-2-yl)allylidenamino)-1-alkyl-1,2,4-triazolium bromides
Published 2024-06-01“…Indeed, the utilization of a diverse array of chemical transformations and functionalizations is crucial for obtaining bioactive molecules with desired properties. …”
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43786
Novel predictive biomarkers for atonic postpartum hemorrhage as explored by proteomics and metabolomics
Published 2025-01-01“…However, there is currently no effective prediction method to promote early management of PPH. In this study, we aimed to screen for potential predictive biomarkers for atonic PPH using combined omics approaches. …”
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43787
Optimal Coordinated Flood Control Scheduling of Three Gorges and Qingjiang Cascade Reservoirs
Published 2025-08-01“…By selecting combinations of different flood areas in the Three Gorges and Qingjiang river basins as model inputs, this study aims to establish a multi-objective joint flood control optimal scheduling model, with innovative optimization of the activation timing and utilization methods for the reservoir group’s flood control capacity. …”
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43788
Incidence of Delirium Tremens in Acute Poisoning by Psychopharmacological Drugs or Corrosive Substances and Its Prevention Using Intestinal Lavage: on the Pathogenesis of Delirium...
Published 2025-04-01“…The observed phenomenon of decreased risk of delirium tremens development in patients who underwent intestinal lavage suggests that the pathogenesis of delirium tremens is associated with morphological and functional disorders of the gastrointestinal tract, the key link of which is the excess proliferation of microflora, for the vital activity of which ethanol is necessary. …”
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43789
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43790
M1hot tumor-associated macrophages boost tissue-resident memory T cells infiltration and survival in human lung cancer
Published 2020-10-01“…Protein expression of genes characteristic of M1-like (chemokine (C-X-C motif) ligand 9) or M2-like (matrix metallopeptidase 12) functions was confirmed by confocal microscopy. Immunohistochemistry related the distribution of TAM transcriptomic signatures to density of CD8+ tissue-resident memory T cells (TRM) in tumors and survival data from an independent cohort of 393 patients with lung cancer.Results TAMs have significantly different transcriptomic profiles from NTAMs with >1000 differentially expressed genes. …”
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43791
Identification of Clusters in a Population With Obesity Using Machine Learning: Secondary Analysis of The Maastricht Study
Published 2025-02-01“…For cluster 3 (n=1149), the most significant continuous variable was overall higher cognitive functioning (mean 0.2349, SD 0.5702 vs mean –0.3088, SD 0.7212; P<.001), and educational level was the most significant categorical variable (P<.001). …”
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43792
Dexamethasone effects on the expression and content of glycosylated components of mouse brain tissue
Published 2023-04-01“…However, even a single use of Dex significantly increased the content of total as well as highly sulfated glycosaminoglycans in the mouse brain tissue, which can lead to the changes in the composition and structure of the brain tissue, as well as its functional characteristics.…”
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43793
Decision-Making Process of Home and Social Care Professionals Using Telemonitoring of Activities of Daily Living for Risk Assessment: Embedded Mixed Methods Multiple-Case Study
Published 2025-04-01“… BackgroundOlder adults with cognitive deficits face difficulties in recalling daily challenges and lack self-awareness, impeding home care clinicians from obtaining reliable information on functional decline and home care needs and possibly resulting in suboptimal service delivery. …”
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43794
Innovative treatment of toxic oily petroleum wastewater with magnetic sludge under UVA light
Published 2025-06-01“…The utilization of these diverse analytical methods provides robust evidence of the structural and functional integrity of the synthesized photocatalyst. …”
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43795
Evaluation of the Antistaphylococcal Activity of the Pyrimidine Derivative
Published 2023-09-01“…Also, the advantage of pyrimidines is the simplicity of the synthesis of new compounds based on them by attaching various functional groups to the heterocycle.Aim. Evaluation of antistaphylococcal activity of a new pyrimidine derivative in vitro and in vivo.Materials and methods. …”
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43796
Neuroprotective Activity of 5-ethoxy-2-ethylthiobenzimidazole (Etomerzol) and 2-ethylthiobenzimidazole (Bemitil) in a Model of Middle Cerebral Artery Occlusion
Published 2023-12-01“…The introduction of bemitil, etomerzol and DMF significantly reduced the neurological deficit 24 hours after OSMA and improved the psycho-functional state on the 7th day. Thus, in the etomerzol group on the first day after surgery, the neurological deficit was reduced by 1.9 times (p < 0.05), and by 3 and 2.0 times (p < 0.05) compared with the control group. …”
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43797
A gut microbiota-independent mechanism shapes the bile acid pool in mice with MASH
Published 2024-11-01“…Background & Aims: An imbalance between primary and secondary bile acids contributes to the development of metabolic dysfunction-associated steatohepatitis (MASH). …”
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43798
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43799
Immunoexpression of tumor suppressor genes p53, p21WAF1/CIP1 and p27KIP1 in humam astrocystic tumors Imuno-expressão dos genes supressores tumorais p53, p21WAF1/CIP1 e p27KIP1 em t...
Published 2007-12-01“…The aim of the present study was to evaluate the tumor suppressor genes p53, p21WAF1/CIP1 and p27KIP1 expression in astrocytic tumors, correlating the findings with the histopathological grade (WHO). …”
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43800
ASSESSMENT OF THE PARAMETERS OF THE INTEROCCLUSION RELATIONSHIP IN THE PROCESS OF MESIALIZATION OF THE LOWER MOLARS WITH THE USE OF T-SCAN
Published 2020-06-01“… The aim of the study. Conduct a digital analysis of the distribution of relative force occlusal load in the area of the second permanent mandibular molars before and after their mesialization. …”
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