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43601
Efficacy of Dry Needling and Intramuscular Dry Needling Stimulation on Quadratus Lumborum in Patients with Mechanical Low Back Pain
Published 2025-04-01“…Outcome measures included pain threshold (assessed with a pressure algometer), postural sway (measured using a sway meter), and functional disability (evaluated using the Oswestry Disability Index, ODI). …”
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43602
MK-4 Ameliorates Diabetic Osteoporosis in Angiogenesis-Dependent Bone Formation by Promoting Mitophagy in Endothelial Cells
Published 2025-03-01“…In vitro, to evaluate the functional level and mitophagy of ECs under high glucose conditions, wound healing assay, tube formation assay, EdU assay and IF were employed. …”
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43603
Exploring the complex interplay between oral Fusobacterium nucleatum infection, periodontitis, and robust microRNA induction, including multiple known oncogenic miRNAs
Published 2025-07-01“…Recently, microRNAs have emerged as critical players in the interactions between host and microbes, and many host functions have been reported to be regulated by miRNAs during infection. …”
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43604
Influence of Urinary Incontinence Related Factors on Health-Related Quality of Life in Patients with Chronic Obstructive Pulmonary Disease: A Cross-Sectional Study
Published 2025-06-01“…Notably, greater UI severity corresponded to more substantial impairments in HRQoL, with severe cases reporting greater negative effects on daily functioning. These findings underscore the importance of routine screening for UI in COPD patients and the implementation of targeted continence care strategies to enhance overall quality of life.Plain Language Summary: This study highlights significant correlations between UI, HRQoL, and factors such as age, BMI, and breathlessness. …”
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43605
Impact of Di-(2-Ethylhexyl)-Phthalate on Metabolic Syndrome: Insights from Network Toxicology and Molecular Docking and Dynamics
Published 2025-07-01“…GO and KEGG pathway analyses were performed using the DAVID database to elucidate biological processes, cellular components, molecular functions, and key pathways (p< 0.05). In addition, molecular docking and molecular dynamics simulations were used to analyze the interactions between compounds and targets further.Results: 150 intersecting targets were identified between DEHP and MetS. …”
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43606
Combined Analysis of Transcriptome and Mendelian Randomization Reveals AKT1 and PPARG as Biomarkers Related to Glucose Metabolism in Sepsis
Published 2025-07-01“…A nomogram model was developed, and biomarker functions were explored through enrichment analysis, immunoinfiltration analysis, transcription factors (TFs) and microRNA (miRNA) prediction, and drug prediction. …”
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43607
Assessment of apoptosis and cell proliferation in patients with intrauterine pathology: A prospective study
Published 2025-01-01“…A decrease in the concentration of apoptosis trigger factors and an increase in soluble Fas, which functions as a "trap," is associated with abnormal induction of programmed death of endometrial cells. …”
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43608
Análisis espacial de datos para clasificar Musáceas en zonas Bananeras no tradicionales del Ecuador
Published 2011-05-01“…It is important to identify varieties of Musa in nontraditional banana´s areas of the country, in order to obtain from them new functions. As a contribution to the statistics on this issue, this project is carried out aimed at identifying physiological descriptors by plants (height of the pseudostem, leaf area, width of margins of the petiole, petiole length, leaf ratio) in areas where there are plants that have characteristics that may be easy to exploit. …”
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43609
Self-reported prevalence and associated factors of work related voice disorders among school teachers in Sekota town, Wag Himra zone, North Ethiopia, 2021: a cross-sectional survey
Published 2025-08-01“…Objectives This study aimed to investigate prevalence and associated factors of work-related voice disorders among school teachers in Sekota town wag himra zone, Ethiopia. …”
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43610
Participatory Intervention Development of a Peer-Guided Self-Help App for Anxiety Disorders: Mixed Methods Study
Published 2025-06-01“…In stage 2, feedback revealed unclear functionality, confusion in peer interaction, and safety concerns, leading to MVP revisions. …”
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43611
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43612
tRFAla-AGC-3-M8 attenuates neuroinflammation and neuronal damage in Alzheimer’s disease via the EphA7-ERK1/2-p70S6K signaling pathway
Published 2025-05-01“…The erythropoietin-producing hepatocellular (Eph) receptor family has recently drawn attention in the study of neurodegenerative diseases due to their role in regulating critical processes, including cell migration, neural development, angiogenesis, and tumor formation. This study aimed to investigate specific tsRNAs associated with AD by performing RNA sequencing on the cortex of APP/PS1 transgenic mice and to explore the relationship between tsRNAs and their target genes within the Eph receptor family, thereby elucidating insights into the specific regulatory functions of these molecules. …”
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43613
Idade e indicações de osteotomias para avanço frontofacial em pacientes com craniossinostoses sindrômicas Age and indications for osteotomy for frontofacial advancement in patients...
Published 2012-06-01“…CONCLUSIONS: In cases of severe craniosynostosis with functional problems, monobloc frontofacial advancement is still the best therapeutic option.…”
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43614
Network pharmacology integrated with molecular docking and experimental validation elucidates the therapeutic potential of Forsythiae Fructus extract against hepatitis B virus-rela...
Published 2025-06-01“…Notably, adenovirus-mediated overexpression experiments showed that ESR1 enhanced FF’s anti-HCC effects, whereas JUN and MMP9 partially counteracted them, confirming their roles as functional targets. In vivo studies further confirmed that FF suppressed tumor growth, reduced serum levels of ALT, AST, TNF-α, and IL-17B in mice, and modulated the expression of core target genes.ConclusionsThe therapeutic potential of FF in HBV-related HCC was demonstrated, with its mechanism likely involving the regulation of multiple components, targets, and pathways. …”
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43615
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43616
Results of Ranibizumab Treatment of the Myopic Choroidal Neovascular Membrane according to the Axial Length of the Eye
Published 2020-01-01“…The effect of ranibizumab treatment on the functional and morphological parameters of the affected eye was evaluated. …”
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43617
Meta-analysis of TB & HIV co-infection mortality rate in sub-Saharan African children, youth, and adolescents
Published 2025-07-01“…The final weighted inverse variance random-effect regression indicated WHO stages III and IV (pooled HR = 4.34), poor/ fair ART adherence (pooled HR = 3.11), missed Isoniazid preventive therapy (IPT) (pooled HR = 3.07), hemoglobin levels ≤ 10 mg/dL (pooled HR = 2.84), bedridden functional status (pooled HR = 3.19), below threshold CD4 count (pooled HR = 1.80), and missed cotrimoxazole preventive therapy (CPT) (pooled AOR = 1.58) were predictors of premature death during co-infection. …”
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43618
Brain Activation During Motor Preparation and Execution in Patients with Mild Cognitive Impairment: An fNIRS Study
Published 2025-03-01“…<b data-eusoft-scrollable-element="1">Objectives:</b> This study aimed to investigate how motor preparation impacted brain activation in individuals with differing cognitive statuses. …”
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43619
Enhanced fire hazard detection in solar power plants: an integrated UAV, AI, and SCADA-based approach
Published 2025-05-01“…This formal logic model intelligently fuses four key binary features, namely, primary defect cause (damage vs. soiling), visual evidence, thermal anomaly severity, and bypass diode functional status, to produce a definitive and context-aware fire risk assessment. …”
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43620
Vessel Wall-Derived Mesenchymal Stromal Cells Share Similar Differentiation Potential and Immunomodulatory Properties with Bone Marrow-Derived Stromal Cells
Published 2020-01-01“…Purpose. This study is aimed at investigating the phenotype, differentiation potential, immunomodulatory properties, and responsiveness of saphenous vein vessel wall-derived mesenchymal stromal cells (SV-MSCs) to various TLR ligands and proinflammatory cytokines, as well as comparing their features to those of their bone marrow-derived counterparts (BM-MSCs). …”
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