Vascular Remodeling Markers in Patients with Essential Arterial Hypertension Depending on Presence of Type 2 Diabetes Mellitus by Yu. A. Danilogorskaya, E. A. Zheleznykh, E. A. Privalova, Yu. N. Belenkov, A. A. Shchendrigina, M. V. Kozhevnikova, G. A. Shakaryants, V. Y. Zektser, A. S. Lishuta, I. S. Ilgisonis

“…Aim. To study some vascular remodeling markers in hypertensive patients depending on the presence of type 2 diabetes mellitus.Material and methods. …”
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POLYMORPHISM OF THE TP53 GENE IN PATIENTS WITH GASTRIC CANCER IN PROSPECTIVE AND CLINICAL CASE-CONTROL STUDIES by A. V. Belkovets, S. A. Kurilovich, V. N. Maksimov, Yu. I. Ragino, L. V. Scherbakova, O. V. Cheremisina, N. V. Cherdyntseva, M. V. Parulikova, M. I. Voevoda

“…Background. A functionally significant TP53Arg72Pro polymorphism can contribute to the development of gastric cancer (GC).The aim: to study the associations of genotypes and alleles of the TP53Arg72Pro 4 polymorphism with GC and biomarkers of gastric ucosal atrophy in population-based prospective and case-control clinical trials among the population of Siberia.Material and methods. …”
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Cinnamaldehyde Alleviates Salmonellosis in Chicks by Regulating Gut Health by Lizi Yin, Luxin Li, Xue Lv, Fengsheng Sun, Yuyun Dai, Yingzi Guo, Shihao Peng, Chenyu Ye, Xiaoxia Liang, Changliang He, Gang Shu, Ping Ouyang

“…CA treatment was the most effective method for reducing PD intestinal colonization and maintaining better intestinal homeostasis, possibly by regulating intestinal microbiota and metabolic functions.…”
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Biochar-compost-based controlled-release nitrogen fertilizer intended for an active microbial community by Robiul Islam RUBEL, Lin WEI, Salman ALANAZI, Abdulkarim ALDEKHAIL, Anne C. M. CIDREIRA, Xufei YANG, Sanjita WASTI, Samarthya BHAGIA, Xianhui ZHAO

“…Fourier-transform infrared spectroscopy (FTIR) analysis revealed that no new functional groups were found in the release solution, indicating no new chemical hazards generated. …”
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The correlation of whole blood viscosity and outcome in mechanical thrombectomy for acute ischemic stroke by Monika Thapa, Jordyn Courville, Reese Leonhard, Prabandh Buchhanolla, Mohammad Abdurrehman Sheikh, Rahul Shah, Prashant Rai, Himanshu Chokhawala, Md Ismail Hossain, Mohammad Alfrad Nobel Bhuiyan, J. Dedrick Jordan, Roger E. Kelley

“…Our results revealed that WBV at high and low shear rates did not impact the functional outcome of mechanical thrombectomy. This result might be affected by the potential limitation of the formula used to derive the given shear rates. …”
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Characterization of the novel cross-genus phage vB_SmaS_QH3 and evaluation of its antibacterial efficacy against Stenotrophomonas maltophilia by Peng Cheng, Peng Cheng, Zian Li, Lanmin Liu, Ruizhe Li, Jianwu Zhou, Xiaoqin Luo, Xiaoqin Luo, Xiaoming Mu, Jingwei Sun, Jideng Ma, Jideng Ma, Xiangren A

“…Based on Illumina whole-genome sequencing data, bioinformatics tools were employed for gene annotation, functional prediction, and phylogenetic analysis. Antimicrobial activity was assessed using in vitro and in vivo models.ResultsA lytic phage vB_SmaS_QH3 was isolated from hospital sewage. …”
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Extracellular vesicles derived from bone marrow mesenchymal stem cells regulate SREBF2/HMGB1 axis by transporting miR-378a-3p to inhibit ferroptosis in intestinal ischemia-reperfus... by Zan Liu, Zitong Zhao, Zhenghui Xiao, Ming Li, Xiyang Wang, Yan Huang, Yong Li

“…Among these, miR-378a-3p was identified as a candidate for regulating ferroptosis. To confirm its functional role, we treated II/R mice with BMSC-EVs overexpressing miR-378a-3p and assessed the outcomes. …”
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Menstrual Morbidities, Menstrual Hygiene, Cultural Practices during Menstruation, and WASH Practices at Schools in Adolescent Girls of North Karnataka, India: A Cross-Sectional Pro... by Rajasri G. Yaliwal, Aruna M. Biradar, Shreedevi S. Kori, Subhashchandra R. Mudanur, Shivakumar U. Pujeri, Mohd Shannawaz

“…The burden of menstruation and cultural practices which the adolescent girls have to face has been less quantified. This study aims to assess the issues related to menstruation in school girls. …”
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Characterization of two novel chia (Salvia hispanica L.) white and black genotypes via DNA barcoding, physiological, and agronomic traits by Clara R. Azzam, Mokhtar Said Rizk, Soha Sayed Mohammad Mostafa, Ramadan A. Arafa, Mohamed Samy Al-Nabawi, Nahid Abdelaty Ali Morsi, Marwa Mahmoud Nasr El-Din, Enass Hassan Taher, Khaled Adly Khaled

“…Background: Chia (Salvia hispanica L.) is recognized for its nutritional value and health-promoting compounds, including flavonoids. Aim: This study utilized DNA barcoding to identify and differentiate two novel chia genotypes, CACH-W and CACH-B, providing insights for breeding programs and genetic resource conservation (CA refers to the developer and CH refer to Chia). …”
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Repetitive prefrontal tDCS activates VTA dopaminergic neurons, resulting in attenuation of Alzheimer’s Disease-like deficits in Tg2576 mice by Maria Luisa De Paolis, Gilda Loffredo, Paraskevi Krashia, Livia La Barbera, Annalisa Nobili, Emma Cauzzi, Lucy Babicola, Matteo Di Segni, Roberto Coccurello, Stefano Puglisi-Allegra, Emanuele Claudio Latagliata, Marcello D’Amelio

“…Moreover, decreased midbrain volume and functional VTA disconnection are identified as predictors of accelerated progression from Mild Cognitive Impairment to AD-dementia in clinical populations. …”
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Identification and validation of three diagnostic autophagy-related genes associated with advanced plaques and immune cell infiltration in carotid atherosclerosis based on integrat... by Tiegen Huang, Chen Su, Quanli Su, Yali Nie, Zhenni Xiao, Yao Tang, Jiahao Wang, Xiaotian Luo, Yixin Tang

“…Background Autophagy plays a key role in the development of carotid atherosclerosis (CAS). This study aimed to identify key autophagy-related genes (ATGs) related with CAS using bioinformatics analysis, in vivo AS mouse model, and in vitro experiments. …”
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Cytokine production by the bioptates of invasive non-specific breast carcinoma as a criterion for the use of acetylamide form of synthetic HLDF-6 peptide for differentiation therap... by E. D. Mangazeeva, A. A. Studenikina, E. S. Michailova, D. V. Morozov, S. L. Ryzhikova, Yu. G. Druzhinina, A. V. Proskura, A. P. Bogachuk, V. M. Lipkin, A. I. Autenshlyus

“…The effect of this peptide may be associated with altered functional activity of the tumour. The aim of our study was to investigate the effect of acetyl-amide form of synthetic HLDF-6 peptide on cytokine production by bioptates of invasive non-specific breast carcinoma. …”
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A real-life study of juvenile idiopathic arthritis from two Brazilian referral centers for pediatric rheumatology by Ana María Loroño Terrazas, Raúl Gutiérrez Suárez, Reinan Tavares Campos, Claudio Arnaldo Len, Nadia Emi Aikawa, Jade Dib Fernandez, Mayra Lisyer Dantas, Clóvis Artur Silva, Gleice Clemente, Maria Teresa Terreri

“…Abstract Background Juvenile idiopathic arthritis (JIA) is the most common rheumatic disease in childhood, but its outcomes are still difficult to determine. We aimed to obtain outcome measurements of disease activity, functional capacity, disease damage, and therapeutic response, at one-year follow-up study on a real-life basis. …”
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Knee-Sparing Resection and Reconstruction Surgery for Bone Sarcoma Using 3D-Surgical Approach: Average of 5-Year Follow-Up by Amit Benady, Noy Yehiel, Ortal Segal, Omri Merose, Amir Sterenheim, Osnat Sher, Ben Efrima, Eran Golden, Yair Gortzak, Solomon Dadia

“…In cases where the tumor arises in the distal femur or proximal tibia near the joint line, knee-sacrificing surgery is typically performed, followed by reconstruction with oncological megaprostheses. This study aims to evaluate the effectiveness of a precise 3D-based surgical approach for knee-sparing tumor resections, assessing its feasibility and its impact on surgical, oncological, and functional outcomes. …”
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Presenting the Model of Effective Factors on Smart Governance in the Country by Ghaem Gheiravani, Mohammad Montazeri, Shams Sadat Zahedi

“…The findings of this research showed that the Islamic Republic's thinker boards at the macro level can help to make the country's governance system smarter and knowledge-based, and in addition to the common functions; it can have functions such as the governing body, guiding and directing the country's macro policies, protection and supervision, explaining the basics, concepts and theoretical frameworks, discourse maker, observation and production of thought, strength of the internal structure of power, socialization and grounding of modern Islamic civilization, use of popular participation and mobilization in the matter of political research and decision making and consultation and problem solving. …”
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Identifying the Dimensions and Components of Virtual Arabic Language Education in Iraq by Abbas Taher Allavi Gharabat, Nasrolah Ghashghaeizadeh, Jalal Shanta Jabir, Faranak mosavi

“…Abstract The aim of this study is to identify the dimensions and components of virtual Arabic language education in Iraq. …”
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An Examination and Critique of Bottom-Up Causation in the Interpretation of Free Will, Focusing on the Non-Reductionist Approach by Tayybhe Gholami, Zahra khazaei

“…However, are human behaviors truly fully determined by the laws of physics or neurobiology? This study aims to examine and critique bottom-up causation in the interpretation of free will through a descriptive-analytical approach and from the perspective of a non-reductionist approach. …”
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Exploring Mortality and Prognostic Factors of Heart Failure with In-Hospital and Emergency Patients by Electronic Medical Records: A Machine Learning Approach by Yu CS, Wu JL, Shih CM, Chiu KL, Chen YD, Chang TH

“…., Taipei, 11049, Taiwan; 5Graduate Institute of Biomedical Informatics, College of Medical Science and Technology, Taipei Medical University, New Taipei City, 235603, Taiwan; 6Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 11031, Taiwan; 7Cardiovascular Research Center, Taipei Medical University Hospital, Taipei, 11031, Taiwan; 8Taipei Heart Institute, Taipei Medical University, Taipei, 11031, Taiwan; 9Department of Family Medicine, Taipei Medical University Hospital, Taipei, 11031, Taiwan; 10School of Medicine, College of Medicine, Taipei Medical University, Taipei, 11031, Taiwan; 11Clinical Big Data Research Center, Taipei Medical University Hospital, Taipei, 11031, Taiwan*These authors contributed equally to this workCorrespondence: Tzu-Hao Chang; Yu-Da Chen, Email kevinchang@tmu.edu.tw; 153072@h.tmu.edu.twPurpose: As HF progresses into advanced HF, patients experience a poor quality of life, distressing symptoms, intensive care use, social distress, and eventual hospital death. We aimed to investigate the relationship between morality and potential prognostic factors among in-patient and emergency patients with HF.Patients and Methods: A case series study: Data are collected from in-hospital and emergency care patients from 2014 to 2021, including their international classification of disease at admission, and laboratory data such as blood count, liver and renal functions, lipid profile, and other biochemistry from the hospital’s electrical medical records. …”
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Benefits and safety of gabapentinoids in chronic low back pain: A systematic review and meta-analysis of randomized controlled trials. by Harsha Shanthanna, Ian Gilron, Manikandan Rajarathinam, Rizq AlAmri, Sriganesh Kamath, Lehana Thabane, Philip J Devereaux, Mohit Bhandari

“…Recent guidelines from the National Health Service (NHS), England, expressed concerns on their off-label use, in addition to the risk of misuse. We aimed to assess the effectiveness and safety of gabapentinoids in adult CLBP patients.…”
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3D culturing as a promising strategy to enhance the angiogenic potential of adipose stem cell-derived secretome: insights into the role of miR-145-5p/ANGPT2 axis by G. Gerini, E. Mari, P. Pontecorvi, S. Camero, E. Romano, D. Ranieri, F. Megiorni, P. Fioramonti, A. Angeloni, C. Marchese, S. Ceccarelli

“…The composition and angiogenic potential of 3D-ASC-derived secretome was assessed by means of protein array and functional tube formation assay, respectively. We analyzed the expression profile of 92 angiogenesis-related genes in 2D versus 3D cultures through a qRT-PCR array, and GO term enrichment analysis followed by network analysis was applied to identify the top hub genes. …”
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